Advanced search
Publication Cover
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration Volume 14, 2013 - Issue 4
Submit an article Journal homepage
656
Views
30
CrossRef citations to date
0
Altmetric
Original Articles

Statins and amyotrophic lateral sclerosis: a systematic review and meta-analysis

Zhenzhen ZhengDepartment of Neurology, West China Hospital of Sichuan University, Chengdu, Sichuan, China
,
Liqin ShengDepartment of Neurology, West China Hospital of Sichuan University, Chengdu, Sichuan, China
&
Huifang ShangDepartment of Neurology, West China Hospital of Sichuan University, Chengdu, Sichuan, ChinaCorrespondence[email protected]
Pages 241-245 | Received 05 Jun 2012, Accepted 15 Sep 2012, Published online: 24 Oct 2012

References

  • John L, Zeller CL, Richard M. Amyotrophic lateral sclerosis. JAMA 2007;298:248.
  • Beltowski J. Statins and ALS: The possible role of impaired LXR signaling. Med Sci Monit. 2010;16:RA73–RA8.
  • Edwards IR, Star K, Kiuru A. Statins, neuromuscular degenerative disease and an amyotrophic lateral sclerosis-like syndrome: an analysis of individual case safety reports from vigibase. Drug Saf. 2007;30:515–25.
  • Harper CR, Jacobson TA. The broad spectrum of statin myopathy: from myalgia to rhabdomyolysis. Curr Opin Lipidol 2007;18:401–8.
  • Chong PHBA, Stevkovic N, et al. Statin-associated peripheral neuropathy: review of the literatures. Pharmacotherapy 2004;24:1194–203.
  • Kiortsis DN, Filippatos TD, Mikhailidis DP, Elisaf MS, Liberopoulos EN. Statin-associated adverse effects beyond muscle and liver toxicity. Atherosclerosis 2007; 195:7–16.
  • Dupuis L, Corcia P, Fergani A, Gonzalez De Aguilar JL, Bonnefont-Rousselot D, Bittar R, et al. Dyslipidemia is a protective factor in amyotrophic lateral sclerosis. Neurology 2008;70:1004–9.
  • Yoshii Y, Hadano S, Otomo A, Kawabe K, Ikeda K, Iwasaki Y. Lower serum lipid levels are related to respiratory impairment in patients with ALS. Neurology 2010;74: 2027–8.
  • Colman E, Szarfman A, Wyeth J, Mosholder A, Jillapalli D, Levine J, et al. An evaluation of a data mining signal for amyotrophic lateral sclerosis and statins detected in FDA’s spontaneous adverse event reporting system. Pharmacoepidemiol Drug Saf. 2008;17:1068–76.
  • Arvanitakis Z, Schneider JA, Wilson RK, Bienias JL, Kelly JF, Evans DA, et al. Statins, incident Alzheimer disease, change in cognitive function, and neuropathology. Neurology 2008;70:1795–802. Epub 2008 Jan 16.
  • Wahner AD, Bronstein JM, Bordelon YM, Ritz B. Statin use and the risk of Parkinson disease. Neurology 2008;70: 1418–22. Epub 2008 Jan 9.
  • Iwamoto K, Yoshii Y, Ikeda K. Atorvastatin treatment attenuates motor neuron degeneration in wobbler mice. Amyotroph Lateral Scler 2009;10:405–9.
  • Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ 2003;327:557–60.
  • Nelson L, Van Den Eeden S, Tanner C, Albers K, McGuire V, Leimpeter A, et al. Cholesterol-lowering drugs and risk of amyotrophic lateral sclerosis: A population-based case-control study. Neuroepidemiology 2009;33:77.
  • Sorensen HT, Riis AH, Lash TL, Pedersen L. Statin use and risk of amyotrophic lateral sclerosis and other motor neuron disorders. Circ Cardiovasc Qual Outcomes. 2010;3:413–7.
  • Drory VE, Bronipolsky T, Artamonov I, Nefussy B. Influence of statins treatment on survival in patients with amyotrophic lateral sclerosis. J Neurol Sci. 2008;273:81–3.
  • Zinman L, Sadeghi R, Gawel M, Patton D, Kiss A. Are statin medications safe in patients with ALS?Amyotroph Lateral Scler 2008;9:223–8.
  • Nefussy B, Hirsch J, Cudkowicz ME, Drory VE. Gender-based effect of statins on functional decline in amyotrophic lateral sclerosis. J Neurol Sci. 2011;300:23–7.
  • Bouteloup C, Desport JC, Clavelous P, Guy N, Derumeaux-Burel H, Ferrier A, et al. Hypermetabolism in ALS patients: an early and persistent phenomenon. J Neurol 2009;256: 1236–42. Epub 2009 Mar 22.
  • Dupuis L, Oudart H, Rene F, Gonzalez De Aguilar JL, Loeffler JP. Evidence for defective energy homeostasis in amyotrophic lateral sclerosis: benefit of a high-energy diet in a transgenic mouse model. Proc Natl Acad Sci USA 2004; 101:11159–64. Epub 2004 Jul 19.
  • Karl F, Per L, Richard W, Phillip R, Li-Jun X, Chun-Qu Y, et al. Lovastatin decreases coenzyme Q levels in humans. Med Sci. 1990;87:8931–34.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.