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ORIGINAL ARTICLE

TGFβ1 genetic variants are associated with an increased risk of acute brucellosis

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Pages 458-464 | Received 10 Oct 2014, Accepted 04 Feb 2015, Published online: 04 Mar 2015

References

  • Pappas G, Memish ZA. Brucellosis in the middle East: a persistent medical, socioeconomic and political issue. J Chemother 2007;19:243–8.
  • Ko J, Gendron-Fitzpatrick A, Splitter GA. Susceptibility of IFN regulatory factor-1 and IFN consensus sequence binding protein-deficient mice to brucellosis. J Immunol 2002; 168:2433–40.
  • Rodriguez-Zapata M, Matias MJ, Prieto A, Jonde MA, Monserrat J, Sanchez L, et al. Human brucellosis is characterized by an intense Th1 profile associated with a defective monocyte function. Infect Immun 2010;78:3272–9.
  • Karaoglan I, Pehlivan S, Namiduru M, Pehlivan M, Kilincarslan C, Balkan Y, et al. TNF-alpha, TGF-beta, IL-10, IL-6 and IFN-gamma gene polymorphisms as risk factors for brucellosis. New Microbiol 2009;32:173–8.
  • Kumar S, Naqvi RA, Khanna N, Pathak P, Rao DN. Th3 immune responses in the progression of leprosy via molecular cross-talks of TGF-beta, CTLA-4 and Cbl-b. Clin Immunol 2011;141:133–42.
  • Bravo MJ, Colmenero JD, Queipo-Ortuno MI, Alonso A, Caballero A. TGF-beta1 and IL-6 gene polymorphism in Spanish brucellosis patients. Cytokine 2008;44:18–21.
  • Xu L, Zeng Z, Chen B, Wu X, Yu J, Xue L, et al. Association between the TGFB1 –509C/T and TGFBR2 –875A/G polymorphisms and gastric cancer: a case-control study. Oncol Lett 2011;2:371–7.
  • Pooja S, Francis A, Rajender S, Tamang R, Rajkumar R, Saini KS, et al. Strong impact of TGF-beta1 gene polymorphisms on breast cancer risk in Indian women: a case-control and population-based study. PLoS One 2013;8:e75979.
  • Amirzargar AA, Rezaei N, Jabbari H, Danesh AA, Khosravi F, Hajabdolbaghi M, et al. Cytokine single nucleotide polymorphisms in Iranian patients with pulmonary tuberculosis. Eur Cytokine Netw 2006;17:84–9.
  • Abbas Z, Moatter T, Hussainy A, Jafri W. Effect of cytokine gene polymorphism on histological activity index, viral load and response to treatment in patients with chronic hepatitis C genotype 3. World J Gastroenterol 2005;11:6656–61.
  • Budak F, Goral G, Heper Y, Yilmaz E, Aymak F, Basturk B, et al. IL-10 and IL-6 gene polymorphisms as potential host susceptibility factors in Brucellosis. Cytokine 2007;38: 32–6.
  • Rafiei A, Hajilooi M, Shakib RJ, Alavi SA. Transforming growth factor-beta1 polymorphisms in patients with brucellosis: an association between codon 10 and 25 polymorphisms and brucellosis. Clin Microbiol Infect 2007; 13:97–100.
  • Eskandari-Nasab E, Moghadampour M, Asadi-Saghandi A, Kharazi-Nejad E, Rezaeifar A, Pourmasoumi H. Levels of interleukin-(IL)-12p40 are markedly increased in Brucellosis among patients with specific IL-12B genotypes. Scand J Immunol 2013;78:85–91.
  • Eskandari-Nasab E, Moghadampour M, Hasani SS, Hadadi-fishani M, Mirghanizadeh-Bafghi SA, Asadi- Saghandi A, et al. Relationship between gamma-interferon gene polymorphisms and susceptibility to brucellosis infection. Microbiol Immunol 2013;57:785–91.
  • El-Koumi MA, Afify M, Al-Zahrani SH. A prospective study of brucellosis in children: relative frequency of pancytopenia. Mediterr J Hematol Infect Dis 2013;5:e2013011.
  • Eskandari-Nasab E, Hashemi M, Rezaei H, Fazaeli A, Mashhadi MA, Moghaddam SS, et al. Evaluation of UDP-glucuronosyltransferase 2B17 (UGT2B17) and dihydrofolate reductase (DHFR) genes deletion and the expression level of NGX6 mRNA in breast cancer. Mol Biol Rep 2012;39:10531–9.
  • Hashemi M, Eskandari-Nasab E, Fazaeli A, Taheri M, Rezaei H, Mashhadi M, et al. Association between polymorphisms of glutathione S-transferase genes (GSTM1, GSTP1 and GSTT1) and breast cancer risk in a sample Iranian population. Biomark Med 2012;6:797–803.
  • Heidari Z, Mahmoudzadeh-Sagheb H, Rigi-Ladiz MA, Taheri M, Moazenni-Roodi A, Hashemi M. Association of TGF-beta1 -509 C/T, 29 C/T and 788 C/T gene polymorphisms with chronic periodontitis: a case-control study. Gene 2013;518:330–4.
  • Arkwright PD, Chase JM, Babbage S, Pravica V, David TJ, Hutchinson IV. Atopic dermatitis is associated with a low-producer transforming growth factor beta(1) cytokine genotype. J Allergy Clin Immunol 2001;108:281–4.
  • Sole X, Guino E, Valls J, Iniesta R, Moreno V. SNPStats: a web tool for the analysis of association studies. Bioinformatics 2006;22:1928–9.
  • Delpino MV, Barrionuevo P, Macedo GC, Oliveira SC, Genaro SD, Scian R, et al. Macrophage-elicited osteoclastogenesis in response to Brucella abortus infection requires TLR2/MyD88-dependent TNF-alpha production. J Leukoc Biol 2012;91:285–98.
  • Reed SG. TGF-beta in infections and infectious diseases. Microbes Infect 1999;1:1313–25.
  • Fiorenza G, Rateni L, Farroni MA, Bogue C, Dlugovitzky DG. TNF-alpha, TGF-beta and NO relationship in sera from tuberculosis (TB) patients of different severity. Immunol Lett 2005;98:45–8.
  • Murthy AK, Sharma J, Coalson JJ, Zhong G, Arulanandam BP. Chlamydia trachomatis pulmonary infection induces greater inflammatory pathology in immunoglobulin A deficient mice. Cell Immunol 2004;230:56–64.
  • Raitala A, Karjalainen J, Oja SS, Kosunen TU, Hurme M. Helicobacter pylori-induced indoleamine 2,3-dioxygenase activity in vivo is regulated by TGFB1 and CTLA4 polymorphisms. Mol Immunol 2007;44:1011–14.
  • Bravo MJ, de Dios Colmenero J, Alonso A, Caballero A. Polymorphisms of the interferon gamma and interleukin 10 genes in human brucellosis. Eur J Immunogenet 2003;30:433–5.
  • Sie MP, Mattace-Raso FU, Uitterlinden AG, Arp PP, Hofman A, Hoeks AP, et al. TGF-beta1 polymorphisms and arterial stiffness; the Rotterdam Study. J Hum Hypertens 2007;21:431–7.
  • Ferrero MC, Fossati CA, Rumbo M, Baldi PC. Brucella invasion of human intestinal epithelial cells elicits a weak proinflammatory response but a significant CCL20 secretion. FEMS Immunol Med Microbiol 2012;66:45–57.
  • Elfaki MG, Al-Hokail AA. Transforming growth factor beta production correlates with depressed lymphocytes function in humans with chronic brucellosis. Microbes Infect 2009;11:1089–96.
  • Rafiei A, Hajilooi M, Shakib RJ, Alavi SA. Transforming growth factor-beta1 polymorphisms in patients with brucellosis: an association between codon 10 and 25 polymorphisms and brucellosis. Clin Microbiol Infect 2007;13:97–100.
  • Suzuki S, Tanaka Y, Orito E, Sugauchi F, Hasegawa I, Sakurai M, et al. Transforming growth factor-beta-1 genetic polymorphism in Japanese patients with chronic hepatitis C virus infection. J Gastroenterol Hepatol 2003; 18:1139–43.

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