22
Views
0
CrossRef citations to date
0
Altmetric
Miscellany

Nordic Netilmicin Symposium: Queens' College, Cambridge, England 13th-17th December, 1979

Pages 1-200 | Published online: 02 Jan 2015

References

  • Hartvig, P. & Nordbring, F.: Var rädd om antibiotikamiljön! Läkartidningen 76: 4630, 1979
  • Kourtopoulos, H. & Holm, S. E.: Intraventricular treatment of Serratia marcescens meningitis with gentamicin. Scand J Infect Dis 8: 57, 1976
  • Legakis, N. J., Tselentis, J., Courtis, K. J. & Papavassiliou, J.: Cross-resistance of clinical isolates of Pseudomonas aeruginosa to five aminoglycosides. J Antimicrob Chemother 5: 487, 1979
  • McCracken, G. H.: Lecture, Symposium on Use of antibiotics in neonates. 19th ICAAC, Boston, Oct. 1979
  • Mawer, G. E.: Aminoglycoside pharmacology. In: Recent advances in infection, p. 121 (ed. D. Reeves & A. Geddes). Churchill Livingstone, Edinburgh, 1979
  • Medical Letter: Hazard of intraventricular antibiotics in neonatal meningitis. Vol. 21, no. 12, p. 52, 1979
  • Moellering, R. C., Jr, Korzeniowski, O. M., Sande, M. A. & Wennersten, C. B.: Species-specific resistance to antimicrobial synergism in Streptococcus faecium and Streptococcus faecalis. J Infect Dis 140: 203, 1979
  • Olsen, L., Grotte, G. & Nordbring, F.: Successful treatment of Pseudomonas aeruginosa-ventriculitis with intraventricular gentamicin in a child with hydrocephalus. Scand J Infect Dis 9: 243, 1977
  • Roberts, N. J., Jr & Douglas, R. G., Jr: Gentamicin use and Pseudomonas and Serratia resistance: Effect of a surgical prophylaxis regimen. Antimicrob Agents Chemother 13: 214, 1978
  • Schentag, J. J., Plaut, M. E., Cerra, F. B., Wels, P. B., Walczak, P. & Buckley, R. J.: Aminoglycoside nephrotoxicity in critically ill surgical patients. J Surg Res 26: 270, 1979

References

  • Barza, M. : Comparative nephrotoxicity of newer cephalosporins and aminoglycosides alone and in combaination in a rat model. Current Chemother 2: 964, 1978
  • Bowman, R. L. : Comparison of the nephrotoxicity of netilmicin and gentamicin in rats. Antimicrob Agents Chemother 12: 474, 1977
  • Brummet, R. E. : Comparative ototoxic liability of netilmicin and gentamicin. Arch Otolaryngol 104: 579, 1978
  • Chiu, P. J. S. : Renal pharmacology of netilmicin. Antimicrobial Agents Chemother 11: 821, 1977
  • Daniels, P. J. L. & Rane, D.: Synthetic and mutasynthetic antibiotics related to sisomicin. Microbiology 314, 1979
  • Federspil, P. J.: Evaluation of the ototoxicity of netilmicin. Curren Chemother 2: 975, 1978
  • Frame, P. T. : Comparative nephrotoxicity of netilmicin and gentamicin in rabbits. Curr Ther Res 24: 344, 1978
  • Kawaguchi, H. : BB-K8, A new semisynthetic aminoglycoside antibiotic. J Antibiotics (Tokyo) 25: 695, 1972
  • Luft, F. C.: Netilmicin: A review of toxicity in laboratory animals. J Int Med Res G: 286, 1978
  • Luft, F. C.: Comparative nephrotoxicity of aminoglycoside antibiotics in rats. J Inf Dis 138: 541, 1978
  • Nagabhushan, T. L.: Interaction of vicinal and non-vicinal amino-hydroxy group pairs in aminoglycoside-aminocyclitol antibiotics with transition metal cations. Selective N protection. J Amer Chem Soc 100: 5253, 1978
  • Wright, J. J.: Synthesis of 1-N-ethylsisomicin. A broad-spectrum semisynthetic aminoglycoside antibiotic. J Chem Soc Chem Comm 6: 206, 1976

References

  • Briedis, D. J. & Robson, H. G.: Comparative activity of netilmicin, gentamicin, amikacin, and tobramycin against Pseudomonas aeruginosa and Enterobacteriaceae. Antimicrob Agents Chemother 10: 592, 1976
  • Closs, O. & Digranes, A.: Rapid identification of prompt lactose-fermenting genera within the family Enterobacteriaceae. Acta Pathol Microbiol Scand (B) 79: 673, 1971
  • Cowan, S. T. & Steel, K. J.: Manual for the identification of medical bacteria. Cambridge University Press, London 1970
  • Dhawan, V., Marso, E., Martin, W. J. & Young, L. S.: In vitro studies with netilmicin compared with amikacin, gentamicin, and tobramycin. Antimicrob Agents Chemother 11: 64, 1977
  • Digranes, A.: Bakterier isolert fra sykehuspasienter: Arter og antibiotikafölsomhet. Norsk gentamicin symposium, Ustaoset, January 18–20, 1977, 58–64
  • Eickhoff, T. C. & Ehret, J. M.: In vitro activity of netilmicin compared with gentamicin, tobramycin, amikacin, and kanamycin. Antimicrob Agents Chemother 11: 791, 1977
  • Ericsson, H. M. & Sherris, J. C.: Antibiotic sensitivity testing. Report of an international collaborative study. Acta Pathol Microbiol Scand (B), Suppl. 217, 1971
  • Fu, K. P. & Neu, H. C.: In vitro study of netilmicin compared with other aminoglycosides. Idem 10: 526, 1976
  • Gilbert, D. N., Kutscher, E., Ireland, P., Barnett, J. A. & Sanford, J. P.: Effect of the concentration of magnesium and calcium on the in-vitro susceptibility of Pseudomonas aeruginosa to gentamicin. J Infect Dis, Suppl. 124: 37, 1971
  • Kabins, S. A., Nathan, C. & Cohen, S.: In vitro comparison of netilmicin, a semisynthetic derivative of sisomicin, and four other aminoglycoside antibiotics. Antimicrob Agents Chemother 10: 139, 1976
  • Klastersky, J., Meunier-Carpentier, F., Coppens-Kahan, L., Daneau, D. & Prevost, J. M.: Clinical and bacteriological evaluation of netilmicin in Gram-negative infections. Antimicrob Agents Chemother 12: 503, 1977
  • Luft, F. C., Yum, M. N. & Kleit, S. A.: Comparative nephrotoxicities of netilmicin and gentamicin in rats. Antimicrob Agents Chemother 10: 845, 1976
  • Marks, M. I., Hammerberg, S., Greenstone, G. & Silver, B.: Activity of newer aminoglycosides and carbenicillin, alone and in combination, against gentamicin-resistant Pseudomonas aeruginosa. Antimicrob Agents Chemother 10: 399, 1976
  • Meyer, R. D., Lewis, R. P., Halter, J. & White, M.: Gentamicin-resistant Pseudomonas aeruginosa and Serratia marcescens in a general hospital. Lancet 1: 580, 1976
  • Miller, G. H., Arcieri, G., Weinstein, M. J. & Waitz, J. A.: Biological activity of netilmicin, a broad-spectrum semisynthetic aminoglycoside antibiotic. Antimicrob Agents Chemother 10: 827, 1976
  • Sandven, P., Lassen, J., Solberg, O. & Evandt, Ø.: Comparative in vitro activity of tobramycin and gentamicin on three different media. Chemotherapy: In press.
  • Snelling, C. F. T., Ronald, A. R., Cates, C. Y. & Forsythe, W. C.: Resistance of gram-negative bacilli to gentamicin. J Infect Dis, Suppl. 124: 264, 1971
  • Stewart, D., Bodey, G. P. & LeBlanc, B.: In vitro studies of netilmicin, a new aminoglycoside antibiotic. Antimicrob Agents Chemother 11: 1017, 1977
  • Watanakunakorn, C.: Comparative in vitro activity of Sch 20656, netilmicin, gentamicin, and tobramycin. Antimicrob Agents Chemother 10: 382, 1976
  • Wersäll, J. & Bjørkroth, B.: Netilmicin, an aminoglycoside antibiotic with low ototoxicity in animal experiments. In: Current chemotherapy (ed. W. Siegenthaler & R. Lüthy), pp. 976–977. Proceedings of the 10th International Congress of Chemotherapy, Zürich, September 1977, American Society for Microbiology, Washington D.C. 1978

References

  • Alfthan, O., Renkonen, O.-V. & Haeger, K.: Netilmicin therapy in patients with complicating gram-negative urinary tract infection: A report on 12 cases. Clin Trials J 15: 55, 1978
  • Chadwick, P., Bruce, A. W., Cooke, T. D. V. & Hardy, G. J.: Therapeutic experience with netilmicin. Can Med Assoc J 119: 1189, 1978
  • Christensson, P., Edén, T., Frolov, I., Jonsson, M., Juhlin, I., Julander, I., Nordström, L., Skånsberg, P., Tjernström, Ö., Tunevall, G. & Wallmark, E.: Efficacy and tolerance of netilmicin in moderate to severe infections. 10th Int. Congr. Chemother. In: Current Chemotherapy, vol. 2, p. 985. American Society for Microbiology, Washington D.C. 1978
  • Digranes, A., Östervold, B., Tschudi Madsen, S., Solberg, C. O. & Haeger, K.: Susceptibility of 327 clinical isolates to netilmicin. J Int Med Res 6: 406, 1978
  • Edén, T., Skånsberg, P. & Haeger, K.: Netilmicin in severe infections: A randomized comparison with gentamicin. Curr Ther Res 24: 96, 1978
  • Goldmann, D. A., Syriopoulou, G. P. & Semple, A. M.: Correlation of netilmicin agar dilution and disc diffusion susceptibilities. Antimicrob Agents Chemother 12: 288, 1977
  • Habwe, V. & Shadomy, S.: In vitro susceptibility studies with netilmicin: Comparison of a 10-μg disc with a standardized 10-μg gentamicin disc. Antimicrob Agents Chemother 13: 1046, 1978
  • Henriksson, P., Svenningsen, N., Juhlin, I. & Haeger, K.: Netilmicin in moderate to severe infections in neonates and infants: A study of efficacy, tolerance and pharmacokinetics. Curr Ther Res 24: 108, 1978
  • Humbert, G., Leroy, A., Fillastre, J. P. & Oksenhendler, G.: Pharmacokinetics of netilmicin in the presence of normal or impaired renal function. Antimicrob Agents Chemother 14: 40, 1978
  • Jepsen, O. B., Mortensen, I. & Rosdahl, V. Thamdrup: Screening methods for detection of β-lactamases in gram-negative bacteria. J Antimicrob Chemother 5: 383, 1979
  • Reyn, A., Bentzon, M. W. & Ericsson, H. M.: Comparative investigations of the sensitivity of N. gnorrhoeae to penicillin. Acta Pathol Microbiol Scand 57: 235, 1963
  • Solberg, C. O., Tschudi Madsen, S., Digranes, A., Stokstad, S., Hellum, K. B., Halvorsen, F. J. & Bakke, K.: High dose netilmicin therapy: Efficacy, tolerance and tissue penetration. 11th Int. Congr. Chemother. 1979. American Society for Microbiology, Abstract No. 672, Boston 1979
  • Thomsen, V. F.: Correlation of the plate-dilution method to the agar diffusion method (disc and tablet methods) with a special view to the importance of pre-diffusion. Acta Pathol Microbiol Scand 54: 107, 1962

References

  • Denneberg, T., Haeger, K. & Juhlin, I.: Netilmicin therapy of serious renal and urinary tract infections in patients with normal and impaired renal function. Scand J Infect Dis.
  • Digranes, A., Östervold, B., Madsen, S., Solberg, C. & Haeger, K.: Susceptibility of 327 clinical isolates to netilmicin. J Int Med Res 6: 409, 1978
  • Ericsson, H. M. & Sherris, J. C.: Antibiotic sensitivity testing. Report of an international collaborative study. Acta Path Microbiol Scand section B, Suppl. 217
  • Jonsson, M., Julander, J. Tunevall, G. & Haeger, K.: Netilmicin treatment of serious infections in patients with renal insufficiency. J Int Med Res 6: 226, 1978
  • Fu, K. P. & Neu, H. C.: In vitro study of netilmicin compared with other aminoglycosides. Antimicrob Agents Chemother 10: 526, 1976
  • Nordström, L., Christensson, P., Haeger, K., Juhlin, I., Tjernström, Ö. & Wallmark, E.: Netilmicin: Clinical evaluation of efficacy and toxicity of a new aminoglycoside. J Int Med Res 7: 117, 1979
  • Phillips, I., Smith, A. & Shannon, K.: Antibacterial activity of netilmicin, a new aminoglycoside antibiotic, compared with that of gentamicin. Antimicrob Agents Chemother 11: 402, 1977
  • Watanakunakorn, C.: Comparative in vitro activity of Sch 20656, netilmicin, gentamicin and tobramycin, Antimicrob Agents Chemother 10: 382, 1976

References

  • Brown, K. N., Benedictson, J. & Swanby, S.: In vitro comparison of gentamicin, tobramycin, sisomicin and netilmicin. Antimicrob Agents Chemother 10: 768, 1976
  • Ericsson, H. M. & Sherris, J. C.: Antibiotic sensitivity testing. Report of an international collaborative study. Acta Pathol Microbiol Scand (B), Suppl. 217, 1971
  • Fu, K. P. & Neu, H. C.: In vitro study of netilmicin compared with other aminoglycosides. Antimicrob Agents Chemother 10: 526, 1976
  • Garrod, L. P. & Waterworth, P. M.: Effect of medium composition on the apparent sensitivity of Pseudomonas aeruginosa to gentamicin. J Clin Pathol 22: 534, 1969
  • Gilbert, D. N., Kutscher, E., Ireland, P., Barnett, J. A. & Sanford, J. P.: Effect of the concentrations of magnesium and calcium on the in vitro susceptibility of Pseudomonas to gentamicin. J Inf Dis 124: 37, 1971
  • Kenny, M. A., Pollock, H. M., Minshew, B. H., Casillas, E. & Schoenknecht, F. D.: Cation components of Mueller-Hinton agar affecting susceptibility testing of Pseudomonas with gentamicin. Antimicrob Agents Chemother 1980. In press.
  • Lennette, E. H., Spaulding, E. H. & Truant, J. P. (eds.): Manual of clinical microbiology, 2nd ed., 1976. American Society for Microbiology
  • Medeiros, A. A., O'Brien, T. F., Wacker, N. E. C. & Yulug, N. F.: Effect of salt concentration on the apparent in vitro susceptibility of Pseudomonas and other gram-negative bacilli to gentamicin. J Inf Dis 124: 559, 1971
  • Miller, G. H., Arcieri, G., Weinstein, M. J. & Waitz, J. A.: Biological activity of netilmicin, a broad-spectrum semisynthetic aminoglycoside antibiotic. Antimicrob Agents Chemother 10: 827, 1976
  • Minshew, B. H., Pollock, H. M., Schoenknecht, F. D. & Sherris, J. C.: Emergence in a burn center of populations of bacteria resistant to gentamicin, tobramycin and amikacin: Evidence for the need for changes in zone diameter interpretative standard. Antimicrob Agents Chemother 12: 688, 1977
  • Pollock, H. M., Minshew, B. H., Kenny, M. A. & Schoenknecht, F. D.: Effect of different lots of Mueller-Hinton agar on the interpretation of the gentamicin susceptibility of Pseudomonas aeruginosa. Antimicrob Agents Chemother 14: 360, 1978
  • Reller, L. B., Schoenknecht, F. D., Kenny, M. A. & Sherris, J. C.: Antibiotic susceptibility testing of Pseudomonas aeruginosa: Selection of a control strain and criteria for magnesium and calcium content in media. J Inf Dis 130: 454, 1974
  • Steers, E., Foltz, E. L. & Graves, B. S.: An inocula replicating apparatus for routine testing of bacterial susceptibility to antibiotics. Antibiot Chemother 9: 307, 1959
  • Wallmark, G., Alestig, K., Dornbusch, K., Ericson, C., Kallings, L. O., Kamme, C., Nordbring, F. & Norrby, R.: Resistance determination of bacteria. A new classification into sensitivity groups S, I and R. Läkartidningen 75: 4346, 1978. (In Swedish, Summary in English.)
  • Washington, J. A., III, Snyder, R. J., Kohner, P. C., Wiltse, C. G., Ilstrup, D. M. & McCall, J. T.: Effect of cation content of agar on the activity of gentamicin, tobramycin and amikacin against Pseudomonas aeruginosa. J Inf Dis 137: 103, 1978
  • Waterworth, P. M.: The aminoglycosides. In: Laboratory methods in antimicrobial chemotherapy eds. D. S. Reeves, I. Phillips, J. D. Williams & R. Wise), Part I, pp. 85–87. Churchill Livingstone, New York

References

  • Davies, J. & Smith, D. I.: Plasmid-determined resistance to antimicrobial agents. Ann Rev Microbiol 32: 469, 1978
  • Miller, G. H., Sabatelli, F. J., Hare, R. S. & Waitz, J. A.: Survey of aminoglycoside resistance patterns. Developm Industr Microbiol 21, 1980

References

  • Carrizosa, J. & Kaye, D.: Penicillin and netilmicin in treatment of experimental enterococcal endocarditis. Antimicrob Agents Chemother 13: 505, 1978
  • Finney, D. J.: Statistical methods in biological assay. 2nd ed. Charles Griffin, London 1964
  • Gutschik, E., Jepsen, O. B. & Mortensen, I.: Effect of combinations of penicillin and aminoglycosides on Streptococcus faecalis: A comparative study of seven aminoglycoside antibiotics. J Infect Dis 135: 832, 1977
  • Moellering, R. C., Jr, Wennersten, C., Medrek, T. & Weinberg, A. N.: Prevalence of high-level resistance to aminoglycosides in clinical isolates of enterococci. Antimicrob Agents Chemother 1970: 335, 1971
  • Reyn, A., Bentzon, M. W. & Ericsson, H.: Comparative investigations of the sensitivity of N. gonorrhoeae to penicillin. Acta Pathol Microbiol Scand 57: 235, 1963
  • Sanders, C. C.: Synergy of penicillin-netilmicin combinations against enterococci including strains highly resistant to streptomycin or kanamycin. Antimicrob Agents Chemother 12: 195, 1977
  • Standiford, H. D., de Maine, J. B. & Kirby, W. M. M.: Antibiotic synergism of enterococci. Arch Intern Med 126: 255, 1970
  • Thomsen, V. F.: Resistensbestemmelse. Dissertation. Nyt Nordisk Forlag, Arnold Busck, København 1967
  • Watanakunakorn, C.: Penicillin combined with gentamicin or streptomycin: Synergism against enterococci. J Infect Dis 124: 581, 1971

References

  • Devaud, M., Kayser, F. H. & Huber, U.: Resistance of bacteria to the newer aminoglycoside antibiotics: An epidemiological and enzymatic study. J Antibiot 30: 655, 1977
  • Kabins, S. A., Nathan, C. & Cohen, S.: In vitro comparison of netilmicin, a semisynthetic derivative of sisomicin, and four other aminoglycoside antibiotics. Antimicrob Agents Chemother 10: 139, 1976
  • Meyer, R. D., Kraus, L. L. & Pasiecznik, K. A.: In vitro susceptibility of gentamicin-resistant Enterobacteriaceae and Pseudomonas aeruginosa to netilmicin and selected aminoglycoside antibiotics. Antimicrob Agents Chemother 10: 677, 1976
  • Miller, G. H., Arcieri, G., Weinstein, M. J. & Waitz, J. A.: Biological activity of netilmicin, a broad-spectrum semisynthetic aminoglycoside antibiotic. Antimicrob Agents Chemother 10: 827, 1976
  • Miller, G. H., Sabatelli, F. J., Hare, R. S. & Waitz, J. A.: Survey of aminoglycoside resistance patterns. Accepted for publication in Devel Ind Microb 21, 1980
  • Minshew, B. H., Pollock, H. M., Schoenknecht, F. D. & Sherris, J. C.: Emergence in a Burn Center of populations of bacteria resistant to gentamicin, tobramycin, and amikacin: Evidence for the need for changes in zone diameter interpretative standards. Antimicrob Agents Chemother 12: 688, 1977
  • Rahal, J. J., Jr, Simberkoff, M. S., Kagan, K. & Moldover, N. H.: Bactericidal efficacy of Sch 20569 and amikacin against gentamicin-sensitive and -resistant organisms. Antimicrob Agents Chemother 9: 595, 1976
  • Phillips, I., Smith, A. & Shannon, K.: Antibacterial activity of netilmicin, a new aminoglycoside antibiotic, compared with that of gentamicin. Antimicrob Agents Chemother 11: 402, 1977
  • Schering-Plough Research Division, USA. Netilmicin: Investigator's Brochure. April 1978
  • Wright, J. J.: Synthesis of 1-N-ethylsisomicin: A broad-spectrum semisynthetic aminoglycoside antibiotic. J Chem Soc Chem Commun 206, 1976

References

  • Arant, B. S., Jr: Developmental patterns of renal functional maturation compared in the human neonate. J Ped 92: 705, 1978
  • Baumueller, A. & Madsen, P. P.: Safety and efficacy of netilmicin in the treatment of patients with complicated urinary tract infections. Clin Ther 4: 244, 1978
  • Carbon, C., Contrepois, A. & Lamotte-Barrillon, S.: Comparative distribution of gentamicin, tobramycin, sisomicin, netilmicin and amikacin in interstitial fluid in rabbits. Antimicrob Agents Chemother 13: 368, 1978
  • Chiu, P. J. S., Brown, A., Miller, G. H. & Long, J. F.: Renal extraction of gentamicin in anaesthetized dogs. Antimicrob Agents Chemother 10: 277, 1976
  • Chiu, P. J. S., Miller, G. H., Brown, A. D., Long, J. F. & Waitz, J. A.: Renal pharmacology of netilmicin. Antimicrob Agents Chemother 11: 821, 1977
  • Follath, F., Spring, P., Wenk, M., Benet, L. Z. & Dettli, I.: Comparative pharmacokinetics of sisomicin and netilmicin in healthy volunteers. In: Proceedings of the 10th International Congress of Chemotherapy, Zürich 1977. Curr Chemother 2: 979, 1978.
  • Gordon, R. C., Regamey, C. & Kirby, W. M. M.: Serum protein binding of the aminoglycoside antibiotics. Antimicrob Agents Chemother 2: 214, 1972
  • Henriksson, P., Svenningsen, N., Kahlmeter, G. & Haeger, K.: Sisomicin treatment of serious neonatal infections. Acta Paed Scand 66: 317, 1977
  • Humbert, G., Leroy, A., Fillastre, J. P. & Oksenhendler, G.: Pharmacokinetics of netilmicin in the presence of normal or impaired renal function. Antimicrob Agents Chemother 14: 40, 1978
  • Jahre, J. A., Fu, K. P. & Neu, H. C.: Kinetics of netilmicin and gentamicin. Clin Pharmacol Ther 23: 303, 1978
  • Jonsson, M., Juhlander, I., Tunevall, G. & Haeger, K.: Netilmicin treatment of serious infections in patients with renal insufficiency. J Int Med Res 6: 226, 1978
  • Kahlmeter, G.: Gentamicin and tobramycin. Clinical pharmacokinetics and nephrotoxicity. Aspects on assay techniques. Scand J Infect Dis, Suppl. 18, 1979
  • Kahlmeter, G., Hallberg, T. & Kamme, C.: Gentamicin and tobramycin in patients with various infections—concentrations in serum and urinary excretion. J Antimicr Chemother 4 ( Suppl. A): 47, 1978
  • Kahlmeter, G., Jonsson, S. & Kamme, C.: Longstanding posttherapeutic gentamicin serum and urine concentrations in patients with unimpaired renal function. A pharmacokinetic evaluation. J Antimicr Chemother 4: 143, 1978
  • Kahlmeter, G., Jonsson, S. & Kamme, C.: Multiple-compartment pharmacokinetics of tobramycin. J Antimicr Chemother 4 ( Suppl. A): 5, 1978
  • Kahlmeter, G. & Kamme, C.: Prolonged excretion of gentamicin in a patient with unimpaired renal function. Lancet i: 286, 1975
  • Kahlmeter, G. & Nilsson-Ehle, P.: To be published.
  • Leroy, A., Humbert, G., Oksenhendler, G. & Fillastre, J. P.: Pharmacokinetics of aminoglycosides in subjects with normal and impaired renal function. Antibiotics Chemother 25: 163, 1978
  • Luft, F. C., Brannon, D. R., Stropes, L. L., Costello, R. J., Sloan, R. S. & Maxwell, D. R.: Pharmacokinetics of netilmicin in patients with renal impairment and in patients on dialysis. Antimicrob Agents Chemother 14: 403, 1978
  • Lode, G., Kemmerich, B. & Koeppe, P.: Comparative clinical pharmacology of gentamicin, sisomicin and tobramycin. Antimicrob Agents Chemother 8: 396, 1975
  • Meyers, B. R., Hirschman, S. Z., Wormser, G. & Siegel, D.: Pharmacokinetic study of netilmicin. Antimicrob Agents Chemother 12: 122, 1977
  • Neu, H. C.: Tobramycin: An overview. J Infect Dis 134 ( Suppl.): 206, 1976
  • Nordström, L., Christensson, P., Haeger, K., Juhlin, I., Tjernström, Ö. & Wallmark, E.: Netilmicin: Clinical evaluation of efficacy and toxicity of a new aminoglycoside. J Int Med Res 7: 117, 1979
  • Norrby, R., Holm, S. E., Rylander, M. & Brorsson, J.-E.: Pharmacokinetics of three cephalosporins, cefoxitin, and four aminoglycosides in rabbits, using subcutaneous steel cages and silicon cylinders. In: Proceedings of the 10th International Congress of Chemotherapy, Zürich, 1977. Curr Chemother 1: 381, 1978.
  • Pechere, J.-C., Dugal, R. & Pechere, M.-M.: Kinetics of netilmicin in man. Clin Pharmacol Ther 23: 677, 1978
  • Pechere, J.-C., Dugal, R. & Pechere, M.-M.: Pharmacokinetics of netilmicin in renal insufficiency and hemodialysis. Clin Pharmacokin 3: 395, 1978
  • Ramirez-Ronda, C. H., Holmes, R. K. & Sandford, J. P.: Effects of divalent cations on binding of aminoglycoside antibiotics to human serum-proteins and to bacteria. Antimicrob Agents Chemother 7: 239, 1975
  • Regamey, C., Gordon, R. C. & Kirby, W. M. M.: Comparative pharmacokinetics of tobramycin and gentamicin. Clin Pharmacol Ther 14: 396, 1973
  • Rubio, T., Wirth, F. & Wellman, L.: Pharmacokinetics of netilmicin in newborn infants. In: Proceedings of the 10th International Congress of Chemotherapy, Zürich, 1977. Curr Chemother 2: 977, 1978.
  • Scheld, W. M., Brown, R. S., Jr & Sande, M. A.: Comparison of netilmicin with gentamicin in the therapy of experimental Escherichia coli meningitis. Antimicrob Agents Chemother 13: 899, 1978
  • Schentag, J. J. & Jusko, W. J.: Renal clearance and tissue accumulation of gentamicin. Clin Pharmacol Ther 22: 364, 1977
  • Siber, G. R., Echeverria, P., Smith, A. L., Paisley, J. W. & Smith, D. H.: Pharmacokinetics of gentamicin in children and adults. J Infect Dis 132: 637, 1975
  • Siegel, J. D., McCracken, G. H., Jr, Thomas, M. L., & Threlkeld, N.: Pharmacokinetic properties of netilmicin in newborn infants. Antimicrob Agents Chemother 15: 246, 1979
  • Welling, P. G., Baumueller, A., Lau, C. C. & Madsen, P. O.: Netilmicin pharmacokinetics after single intravenous doses to elderly male patients. Antimicrob Agents Chemother 12: 328, 1977

References

  • Appel, G. B. & Neu, H. C.: The nephrotoxicity of antimicrobial agents. N Engl J Med 296: 722, 1977
  • Aubert-Tulkens, G., VanHoof, F. & Tulkens, P.: Gentamicin-induced lysosomal phospholipidosis in cultured rat fibroblasts. Lab Invest 40: 481, 1979
  • Baylis, C., Rennke, H. R. & Brenner, B. M.: Mechanisms of the defect in glomerular ultrafiltration associated with gentamicin administration. Kidney Int 12: 344, 1977
  • Bloch, R., Luft, F. C., Rankin, L. I., Sloan, R. S., Yum, M. N. & Maxwell, D. R.: Protection from gentamicin nephrotoxicity by cephalothin and carbenicillin. Antimicrob Agents Chemother 15: 46, 1979
  • Bowman, R. L., Silverblatt, F. J. & Kaloyanides, G. J.: Comparison of netilmicin and gentamicin in rats. Antimicrob Agents Chemother 12: 474, 1977
  • Brier, G. L., Wolney, J. & Smith, J. W.: Serum bioassay for antimicrobial agents. In: Technical Improvement Service, No. 21, p. 57. American Society of Clinical Pathologists publication, Chicago, Il. 1975
  • Chiu, P. J. S., Miller, G. H., Brown, A. D., Long, J. F. & Waitz, J. A.: Renal pharmacology of netilmicin. Antimicrob Agents Chemother 11: 821, 1977
  • Chonko, A., Savin, V., Stewart, R., Karniski, L., Cuppage, F. & Hodges, G.: The effects of gentamicin on renal function in the mature vs. immature rabbit. Proc Am Soc Nephrol 12: 2, 1979
  • Collier, V. U., Lietman, P. S. & Mitch, W. E.: Evidence for luminal uptake of gentamicin in the perfused rat kidney. J Pharmacol Exp Ther 210: 247, 1979
  • Cronin, R. E., Bulger, R. E., Southern, P. & Henrich, W. L.: Natural history of aminoglycoside nephrotoxicity in the dog. J Lab Clin Med (in press)
  • Diack, S. L.: The determination of surface area in the white rat. J Nutr 3: 289, 1930
  • Evan, A. P., Huser, J., Avasthi, P. S., Rankin, L. I. & Luft, F. C.: Gentamicin induced glomerular injury. Proc Intersci Conf Antimicrob Agents Chemother. In: Current Chemotherapy p. 590 (ed. J. Nelson & C. Grassi) American Society of Microbiology publication, Washington D.C. 1980
  • Hagstrom, G. L., Luft, F. C., Yum, M. N., Sloan, R. S. & Maxwell, D. R.: Nephrotoxicity of netilmicin in combination with non-aminoglycoside antibiotics. Antimicrob Agents Chemother 13: 490, 1978
  • Houghton, D. C., Hartnett, M., Campbell-Boswell, M. Porter, G. & Bennett, W. A.: A light and microscopic analysis of gentamicin nephrotoxicity in rats. Am J Pathol 82: 589, 1976
  • Just, M., Erdmann, G. & Habermann, E.: The renal handling of polybasic drugs: I. Gentamicin and aprotinin in intact animals. Naunyn-Schmedeberg's Arch Pharmacol 300: 57, 1977
  • Kosek, J. C., Mazze, R. I. & Cousins, M. J.: Nephrotoxicity of gentamicin. Lab Invest 30: 48, 1974
  • Luft, F. C.: Netilmicin: A review of toxicity in laboratory animals. J Int Med Res 6: 286, 1978
  • Luft, F. C., Bloch, R., Sloan, R. S., Yum, M. N., Costello, R. & Maxwell, D. R.: Comparative nephrotoxicity of aminoglycoside antibiotics in rats. J Infect Dis 138: 541, 1978
  • Luft, F. C. & Kleit, S. A.: Renal parenchymal accumulation of aminoglycoside antibiotics in rats. J Infect Dis 130: 656, 1974
  • Luft, F. C., Patel, V., Yum, M. N., Patel, B. & Kleit, S. A.: Experimental aminoglycoside nephrotoxicity. J Lab Clin Med 86: 213, 1975
  • Luft, F. C., Rankin, L. I., Sloan, R. S. & Yum, M. N.: Recovery from aminoglycoside nephrotoxicity with continued drug administration. Antimicrob Agents Chemother 14: 284, 1979
  • Luft, F. C., Yum, M. N. & Kleit, S. A.: Comparative nephrotoxicities of netilmicin and gentamicin in rats. Antimicrob Agents Chemother 10: 845, 1976
  • Luft, F. C., Yum, M. N., Walker, P. D. & Kleit, S. A.: Gentamicin gradient patterns and morphologic changes in human kidneys. Nephron 18: 167, 1977
  • Marsh, W. H., Fingerhut, B. & Miller, H.: Automated and manual direct methods for the determination of blood urea. Clin Chem 11: 624, 1965
  • Mondorf, A. W., Zegelman, M., Klose, J., Hendus, J. & Breier, J.: Comparative studies on the action of aminoglycosides and cephalosporins on the proximal tubule of the human kidney. In: Current Chemotherapy, p. 966 (ed. W. Siegenthaler & R. Lüthy). American Society of Microbiology publication, Washington, D.C., 1978
  • Morin, J. P., Fillastre, J. P. & Vaillant, R.: Prediction of aminoglycoside-cephalosporin nephrotoxicity. In: Current Chemotherapy, p. 960 (ed. W. Siegenthaler & R. Lüthy). American Society of Microbiology publication, Washington, D.C., 1978
  • Natelson, S. In: Techniques of clinical chemistry, p. 606. Charles C. Thomas, Springfield, Il., 1971
  • Pastoriza-Muñoz, E., Bowman, R. L. & Kalayanides, G. L.: Renal tubular transport of gentamicin in the rat. Kidney Int 16: 440, 1979
  • Patel, V., Luft, F. C., Yum, M. N., Patel, B., Zeman, W. & Kleit, S. A.: Enzymuria in gentamicin-induced kidney damage. Antimicrob Agents Chemother 7: 364, 1975
  • Roos, R. & Jackson, G. G.: Protective effect of cephalosporin on gentamicin nephrotoxicity: Effect of cephalothin anion, not sodium cation. In: Current Chemotherapy, p. 962 (ed. W. Siegenthaler & R. Lüthy). American Society of Microbiology publication, Washington, D.C. 1978
  • Silverblatt, F. J. & Knehn, C.: Autoradiography of gentamicin uptake by the rat proximal tubule cell. Kidney Int 15: 335, 1979
  • Simmons, C. F., Bogusky, R. T. & Humes, H. D.: Inhibitory effects of gentamicin on renal cortical mitochondrial oxidative phosphorylation: A primary pathogenetic event in gentamicin nephrotoxicity. Proc Am Soc Nephrol 12: 6, 1979
  • Soberon, L., Bowman, R. L., Pastoriza-Muñoz, E. & Kalyanides, G. L.: Comparative nephrotoxicities of gentamicin, netilmicin, and tobramycin in the rat. J Pharmacol Exp Ther 210: 334, 1979
  • Wade, J. C., Smith, C. R., Petty, B. G., Lipsky, J. J., Conrad, G., Ellner, J. & Lietman, P. S.: Cephalothin plus an aminoglycoside is more nephrotoxic than methicillin plus an aminoglycoside. Lancet iii: 604, 1978

References

  • Thompson, W. L., Reiner, N. E. & Bloxham, D. D.: Nephrotoxicity of amphotericin B and aminoglycoside antibiotics in dogs. Proceedings of the Pharmacology-Toxicylogy Symposium of the National Institutes of Health, 1977
  • Reiner, N. E., Bloxham, D. D. & Thompson, W. L.: Nephrotoxicity of gentamicin and tobramycin given once daily or continuously in dogs. J Antimicrobial Chemotherapy 4: 85, 1978
  • Bloxham, D. D., Meliere, C. C. & Thompson, W. L.: Aminoglycoside nephrotoxicity: Effects of dosage regimen and cephalothin. Clin Res 26: 286A, 1978
  • Powell, S. H., Gorden, D. L., Thompson, W. L. & Stern, R. C.: Aminoglycoside efficacy and toxicity: Once daily versus continuous dosing. Clin Res 27: 353A, 1979
  • Powell, S. H., Stern, R. C. & Thompson, W. L.: Safety of once daily therapy with highdose tobramycin. Ped Res 13: 466, 1977 (abstract no 842)

References

  • Adelman, R. D., Spangler, W., Beasom, F. & Ischizaki, G.: A comparison of the nephrotoxicity of gentamicin and netilmicin when given with furosemide. Clin Res 27: 96 (abstract), 1979
  • Alfthan, O., Renkonen, O. & Haeger, K.: Netilmicin therapy in patients with complicating gram-negative urinary tract infection. Clin Trial J 15: 55, 1978
  • Aubert-Tulkens, G., VanHoof, F., & Tulkens, P.: Gentamicin-induced lysosomal phospholipidosis in cultured rat fibroblasts. Lab Invest 40: 481, 1979
  • Barza, M., Pinn, V., Tanguay, P. & Murray, T.: Nephrotoxicity of newer cephalosporins and aminoglycosides alone and in combination in a rat model. J Antimicrob Chemother 4: Suppl 59, 1978
  • Baylis, C., Rennke, H. R. & Brenner, B. M.: Mechanisms of the defect in glomerular ultrafiltration associated with gentamicin administration. Kidney Int 2: 344, 1977
  • Bloxham, D. D., Meliere, C. C. & Thompson, W. L.: Aminoglycoside nephrotoxicity: Effects of dosage regimen and cephalothin. Clinical Res 26: 286A (abstract). 1978
  • Bowman, R. L., Silverblatt, F. J. & Kaloyanides, G. J.: Comparison of the nephrotoxicity of Netilmicin and Gentamicin in rats. Antimicrob Agents Chemother 12: 474, 1977
  • Brandenhoff, P., Stafanger, G., Gammelgaard, P. A., Rasmussen, F., Holm-Jensen, S., Bretlau, P. & Frølund Thomsen. V.: Netilmicin therapy of patients with septicaemia and other severe infections. Preliminary results. Scand J Infects Dis. Suppl. 23: 181, 1980
  • Buckwold, F. J., Ronald, A. R., Lank, B., Thompson, L., Fox, L. & Harding, G. K. M.: Clinical efficacy and toxicity of netilmicin in the treatment of gram-negative infections. CMA Journal 120: 161, 1979
  • Chiu, P. J. S., Brown, A. D., Miller, G. H. & Long, J. F.: Renal extraction of gentamicin in anesthetized dogs. Antimicrob Agents Chemother 10: 277, 1976
  • Chiu, P. J. S., Miller, G. H., Brown, A. D., Long, J. F. & Waitz, J. A.: Renal pharmacology of Netilmicin. Antimicrob Agents Chemother 11: 821, 1977
  • Denneberg, T., Haeger, K. & Juhlin, I.: Netilmicin therapy of serious renal and urinary tract infections in patients with normal and impaired renal function. Scand J Infect Dis. Suppl. 23: 135, 1980
  • Dikman, S., Bosch, J., Churg, J. & Kahn, T.: Gentamicin and Netilmicin nephrotoxicity. Clinical Res 25: 429A (abstract), 1977
  • Edelstein, P. H. & Meyer, R. D.: Netilmicin therapy of serious gram-negative bacillary infections. Proc. loth Int. Congress of Chemotherapy, Zürich, Switzerland 1977. Current Chemother 2: 982, 1978
  • Engle, J. E., Abt, A. B. & Schoolwerth, A. C.: Comparison of nephrotoxicity of netilmicin and tobramycin in dogs. Kidney Int 12: 466 (abstract), 1977
  • Engle, J. E., Abt. A. B., Schneck, D. W. & Schoolwerth, A. C.: Submitted for publication 1979
  • Evan, A. P., Huser, J., Arasthi, P. S., Rankin, L. I. & Luft, F. C.: Gentamicin induced glomerular injury. Proc Intersc Conf Antimicrob Agents Chemother 19: 933, 1979
  • Fabre, J., Rudhardi, M., Blanchard, P. & Regamey, C.: Persistence of sisomicin and gentamicin in renal cortex and medulla compared with other organs and serum of rats. Kidney Int 10: 444, 1976
  • Frame, P. T., Watanakunakorn, C. & Cluxton, R. J.: Comparative nephrotoxicity of netilmicin and gentamicin in rabbits. Curr Therap Res 24: 344, 1978
  • Geisler, C., Mørk Hansen, M. & Mortensen, N.: Netilmicin therapy of patients with leukemia and malignant lymphoma. Scand J Infect Dis, Suppl. 23: 176, 1980
  • Gingell, J. C., Chisholm, G. D., Calnan, J. S. & Waterworth, P. M.: The dose, distribution, and excretion of gentamicin with special reference to renal failure. J Inf Dis 119: 396, 1969
  • Hagstrom, G. L., Luft, F. C., Yum, M. N., Sloan, R. S. & Maxwell, D. R.: Nephrotoxicity of Netilmicin in combination with non-aminoglycoside antibiotics. Antimicrob Agents Chemother 13: 490, 1978
  • Hellum, K. B., Madsen, S. T., Digranes, A., Stokstad, S. & Solberg, C. O.: High-dose netilmicin therapy of severe or chronic infections. Scand J Infect Dis, Suppl. 23: 189, 1980
  • Houghton, D. C., Hartnett, M., Campbell-Boswell, M., Porter, G. & Bennett, W.: A light and electron microscopic analysis of Gentamicin nephrotoxicity in rats. Am J Pathol 82: 591, 1976
  • Igarashi, M., Levy, J. K. & Jerger, J.: Comparative toxicity of netilmicin and gentamicin in squirrel monkeys (Saimiri sciureus). J Inf Dis 137: 476, 1978
  • Jahre, J. A., Fu, K. P. & Neu, H. C.: Clinical evaluation of netilmicin therapy in serious infections. JAMA 66: 67, 1979
  • Jonsson, M., Julander, I., Tunewall, G. & Haeger, K.: Netilmicin treatment of serious infections in patients with renal insufficiency. J Int Med Res 6: 226, 1978
  • Kahlmeter, G.: Gentamicin and tobramycin. Clinical pharmacokinetics and nephrotoxicity. Aspects on Assay Techniques. Diss., Lund 1979
  • Kahn, T.: Effect of furosemide on gentamicin and netilmicin nephrotoxicity. Kidney Int 12: 527 (abstract), 1977
  • Klastersky, J., Meunier-Carpentier, F., Coppens-Kaham, L., Daneau, D. & Prevost, J. M.: Clinical and bacteriological evaluation of netilmicin in gram-negative infections. Antimicrob Agents Chemother 12: 503, 1977
  • Kornguth, M. L. & Kunin, C. M.: Distribution of Gentamicin and amikacin in rabbit tissues. Antimicrob Agents Chemother 11: 974, 1977
  • Kosek, J. C., Mazze, R. I. & Cousins, M. J.: Nephrotoxicity of Gentamicin. Lab Invest 30: 48, 1974
  • Luft, F. C.: Netilmicin: A review of toxicity in laboratory animals. J Int Med Res 6, 286, 1978
  • Luft, F. C., Bloch, R., Sloan, R. S., Yum, M. N., Costello, R. & Maxwell, D. R.: Comparative nephrotoxicity of aminoglycoside antibiotics in rats. J Infect Dis 138: 541, 1978
  • Luft, F. C. & Kleit, S. A.: Renal parenchymal accumulation of aminoglycoside antibiotics in rats. J Infect Dis 130: 656, 1974
  • Luft, F. C., Rankin, L. I., Sloan, R. S. & Yum, M. N.: Recovery from aminoglycoside nephrotoxicity with continued drug administration. Antimicrob Agents Chemother 3: 284, 1978
  • Luft, F. C., Yum, M. N. & Kleit, S. A.: Comparative nephrotoxicities of Netilmicin and Gentamicin in rats. Antimicrob Agents Chemother 10: 845, 1976
  • Maigaard, S., Frimodt-Møller, N. & Madsen, P. O.: Comparison of netilmicin and amikacin in treatment of complicated urinary tract infections. Antimicrob Agents Chemother 14: 544, 1978
  • Mondorf, A. W., Zegelman, M., Klose, J., Hendus, J. & Breier, J.: Comparative studies on the action of aminoglycosides and cephalosporins on the proximal tubule of the human kidney. J Antimicrob. Chemother: 4 ( suppl. A), 53, 1978
  • Nordström, L., Christensson, P., Haeger, K., Juhlin, I., Tjernström, O. & Wallmark, E.: Netilmicin: Clinical evaluation of efficacy and toxicity of a new aminoglycoxide. J Int Med Res 7: 117, 1979
  • Ormsby, A. M., Parker, R. A., Plamp, C. E., Stevens, P., Houghton, D. C., Gilbert, D. N. & Bennett, W. M.: Comparison of the nephrotoxic potential of Gentamicin, tobramycin and Netilmicin in the rat. Curr Ther Res 25: 335, 1979
  • Panwalker, A. P., Malow, J. B., Zimelis, V. M. & Jackson, G. G.: Netilmicin: Clinical efficacy, tolerance and toxicity. Antimicr Agents Chemother 13: 170, 1978
  • Pastoriza-Munoz, E., Bowman, R. L. & Kaloyanides, G. J.: Renal tubular transport of gentamicin in the rat. Kidnev Int 16: 440, 1979
  • Raab, W. P.: Nephrotoxicity of various aminoglycoside antibiotics, evaluated by renal enzyme excretion studies. Current Chemother 2: 938, 1978
  • Silverblatt, F. J. & Kuehn, C.: Autoradiography of gentamicin uptake by the rat proximal tubule cell. Kidney In 15: 335, 1979
  • Smith, C. R., Lipsky, J. J., Laskin, O. L., Hellmann, D. B., Mellits, E. D., Longstreth, J. & Lietman, P. S.: Double-blind comparison of the nephrotoxicity and auditory toxicity of gentamicin and tobramycin. New Engl J Med 302: 1106, 1980
  • Snydman, D. R., Tally, F. P., Landesman, S. H., Barza, M. & Corbach, J. L.: Netilmicin in gram-negative bacterial infections. Antimicr Agents Chemother 15: 50, 1979
  • Soberon, L., Bowman, R. L., Pastoriza-Munoz, E. & Kaloyanides G. J.: Comparative nephrotoxicities of gentamicin, netilmicin and tobramycin in the rat. J Pharmacol Exp Therap 210: 334, 1979
  • Svare, J., Johnsen, N. J., Vesterhauge, S., Lund, F., Thomsen, J. & Vejlsgaard, R.: Netilmicin in urinary tract infections. Scand J Infect Dis, Suppl. 23: 132, 1980
  • Szot, R., Weinberg, E., McCormick, G., Christie, B. & Schwarts, E.: Submitted for publication 1979
  • Trestman, I., Parsons, J., Santoro, J., Goodhart, G. & Kaye, D.: Pharmacology and efficacy of netilmicin. Antimicr Agents Chemother 13: 832, 1978
  • Whelton, A., Carter, G. G., Craig, T. J., Bryant, H. H., Herbst, D. V. & Walker, W. G.: Comparison of the intrarenal disposition of tobramycin and gentamicin: Therapeutic and toxicologic answers. J Antimicrob Chemother 4: suppl. A, 13, 1978
  • Whelton, A. & Walker, W. G.: Intratenal antibiotic distribution in health and disease. Kidney Int 6: 131, 1974
  • Weinberg, E. H., Robbins, G. R. & Schwarts, E.: Preclinical toxicologic studies of netilmicin. Toxicol., Appl. Pharmacol. 1978
  • Weinberg, E. H., Field, W. E., Gray, W. D., Klein, M. F., Robbins, G. R. & Schwarts, E.: Toxicol Appl. Pharmacol. Submitted for publication, 1979

References

  • Bernard, A., Pechere, J. C. & Jequier, J. C.: Detection of tobramycin and netilmicin induced ototoxicity in guinea pigs with evoked action potentials. J Infect Dis 139: 418, 1979
  • Brummett, R. E., Fox, K. E., Brown, R. T. & Humes, D. L.: Comparative ototoxic liability of netilmicin and gentamicin. Arch Otolaryngol 104: 579, 1978
  • Ernstson, S.: Cochlear physiology and hair cell population in a strain of the waltzing guinea pig. Acta Otolaryngol (Stockh.), Suppl. 297, 1972
  • Federspil, P.: Das Cochleogramm des normalen Meerschweinchens. Arch Klin Exp Ohren Nasen Kehlkopfheilkd 201: 283, 1972
  • Federspil, P.: ototoxicity and nephrotoxicity of netilmicin. Infection 4: 211, 1976
  • Igarashi, M., Levy, J. K. & Jerger, J.: Comparative toxicity of netilmicin and gentamicin in squirrel monkeys. J Infect Dis 137: 476, 1978
  • Miller, G. H., Arcieri, G., Weistein, M. J. & Waitz, J. A.: Biological activity of netilmicin, a broad-spectrum semisynthetic aminoglycoside antibiotic. Antimicrob Agents Chemother 10: 827, 1976
  • Weinberg, E. H., Robbins, G. R. & Schwartz, E. Preclinical toxicologic studies of netilmicin. Toxicology and Applied Pharmacology, 1978
  • Wersäll, J.: Studies on the structure and innervation of the sensory epithelium of the cristae ampullares in the guinea pig. A light and electron microscopic investigation. Thesis. Acta Otolaryngol (Stockh.), Suppl. 126: 1–85, 1956
  • Wersäll, J. & Björkroth, B.: Netilmicin, an aminoglycoside antibiotic with low ototoxicity in animal experiments. International Society of Chemotherapy Published by American Society for Microbiology Reprinted from Current Chemotherapy, pp. 976–977, 1978
  • Wersäll, J., Björkroth, B., Flock, Å. & Lundquist, P.-G.: Sensory hair fusion in vestibular sensory cells after gentamycin exposure. A transmission in scanning electron microscope study. Arch Klin Exp Ohren Nasen Kehlkopfheilkd 200: 1, 1971
  • Úhlelóva, L. & Voldrich, L.: Idiopathic hair cell loss in the guinea pig. Arch Oto-rhinolaryngol 221: 7, 1978

References

  • Bergström, L. W., Jenkins, P., Sando, I. & English, G. M.: Hearing Loss in renal disease: Clinical and pathological studies. Ann Otol (St. Louis) 82: 555, 1973
  • Black, R. E., Lau, W. K., Weinstein, R. J., Young, L. S. & Hewitt, W. L.: Ototoxicity of Amicacin. Antimicrob Agents Chemother 9: 956, 1976
  • Eggermont, J. J.: Electrocochleography. In: Handbook of sensory physiology, vol. V/3 ed. W. E. Keidel & W. D. Neff). Springer- Verlag, Berlin, Heidelberg, New York
  • Jørgensen, M. B.: The inner ear in diabetes mellitus. Arch Otolaryngol 74: 373, 1961
  • Nordström, L.: Personal experience of Gentamicin ototoxicity. In: Round table discussion on Gentamicin and Tobramycin, p. 39 (ed. R. G. Richardson). The Royal Society of Medicine, International Congress and Symposium Series 4, Academic Press, London. Grune & Stratton, New York 1978
  • Reeves, D.: The frequency of ototoxicity—a review of the literature. In: Round table discussion on Gentamicin and Tobramycin, p. 45 (ed. R. G. Richardson). The Royal Society of Medicine, International Congress and Sumposium Series 4, Academic Press, London; Grune & Stratton, New York 1978
  • Stockard, J. J., Stockard, J. E. & Sharbrough, F. W.: Detection and localization of occult leasions with brain stem auditory responses. Mayo Clinic Proc 52: 761, 1977
  • Suga, F., Preston, J. & Snow, J. B.: Experimental microembolization of cochlear vessels. Arch Otolaryngol 92: 213, 1970
  • Tjernström, O., Banck, G., Belfrage, S., Juhlin, I., Nordström, L. & Toremalm, N. G.: The ototoxicity of Gentamicin. Acta Pathol Microbiol Scand B 81, Suppl. 241: 73, 1973

References

  • Brummet, R. E., Fox, K. E., Brown, R. T. & Himes, D. L.: Comparative ototoxic liability of netilmicin and gentamicin. Arch Otolaryng 104: 579, 1979
  • Jerger, J., Burney, P., Maudlin, L. & Crump, B.: Predicting hearing loss from the acoustic reflex. J Speech Hearing Dis 18: 11, 1974
  • Johnsen, N. J., Osterhammel, D., Terkildsen, K., Osterhammel, P. & Huis in't Veld, F.: The white noise middle ear muscle reflex threshold in patients with sensorineural hearing impairment. Scand Audiol 5: 131, 1976
  • Johnsen, N. J. & Terkildsen, K.: The normal middle ear reflex thresholds towards white noise and acoustic clicks in young adults. Scand Audiol, in press, 1979
  • Jonsson, M., Julander, I., Tunevall, G. & Haeger, K.: Netilmicin treatment of serious infections in patients with renal insufficiency. J Int Med Res 6: 226, 1978
  • Löwenstein, O. & Sand, A.: The mechanism of the semicircular canal. Proc Roy Soc Med B 129: 256, 1940
  • Møller, N. E., Koch, C., Vesterhauge, S. & Jensen, K.: Treatment of pulmonary Pseudomonas aeruginosa-infection in cystic fibrosis with a new cephalosporin; CGP-7174 (cefsulodinr). Submitted for publication in The Lancet.
  • Schmaltz, G.: The physical phenomena occurring in the semicircular canals during rotatory and thermic stimulation. Proc Roy Soc Med 25: 339, 1932
  • Sills, W., Honrubia, V. & Kumley, W. E.: Algorithm for the multi-parameter analysis of nystagmus using a digital computer. Aviat Space Environ Med 46: 934, 1975
  • Svare, J., Vesterhauge, S., Johnsen, N. J., Vejlsgård, R., Thomsen, J. & Lund, F.: Netilmicin in urinary tract infection. Scand J Infect Dis, Suppl. 23: 132, 1980
  • Vesterhauge, S., Runge, B., Månsson, A. & Zilstorff, K.: Computer analysis of electronystagmographic data. Accepted for publication in Clin Otolaryngol.
  • Wersäll, J. & Björkroth, B.: Netilmicin, an aminoglycoside antibiotic with low ototoxicity in experimental animals. 10th International Congress of Chemotherapy, p. 381, Zürich, 1977

References

  • Brummet, R. E., Kaye, E. F., Brown, R. T. & Hines, L.: Comparative ototoxic liability of netilmicin and gentamicin. Arch Otolaryngol 104: 579, 1978
  • Buckwold, B. J., Ronald, A. R., Lank, B., Thompson, L., Fox, L. & Harding, G. K. M.: Clinical efficacy and toxicity of netilmicin in the treatment of gram-negative infections. CMA Journal 120: 161, 1979
  • Jonsson, M., Julander, I., Tunewall, G. & Haeger, K.: Netilmicin treatment of serious infections in patients with renal insufficiency. J Int Med Res 6: 226, 1978
  • Nordström, L., Banck, G., Belfrage, S., Juhlin, I., Tjernström, Ö. & Toremalm, N. G.: Prospective study of the ototoxicity of gentamicin. Acta Pathol Microbiol Scand, Suppl 241: 58, 1973
  • Nordström, L.: Personal experience of gentamicin ototoxicity. Round table discussion on gentamicin and tobramicin. The Royal Society of Medicine. International Congress and Symposium Series No. 4, 1978
  • Schering Corporation Limited: Informational material for the investigational drug netilmicin. Bloomfield, N. J., 1977

References

  • Bauer, A. W., Kirby, W. M., Sherris, J. E. & Turck, M.: Antibiotic susceptibility testing by a standardized single disk method. Am J Clin Pathol 36: 439, 1966
  • Baumueller, A. & Madsen, P. O.: Safety and efficacy of netilmicin in the treatment of patients with complicated urinary tract infection. Clinical Therapeutics 1: 244, 1978
  • Brøchner-Mortensen, J.: Routine methods and their reliability for assessment of glomerular filtration rate in adults—with special reference to total [51Cr] EDTA plasma clearance. Laegeforeningens Forlag, Copenhagen, Denmark, 1978 (thesis)
  • Frimodt-Møller, N., Maigaard, S. & Madsen, P. O.: Netilmicin treatment of complicated urinary tract infection in patients with renal function impairment. Antimicrob Agents Chemother 16: 406, 1979
  • Hoyme, U. & Madsen, P. O.: Netilmicin and tobramycin in the therapy of complicated urinary tract infections. Current Chemotherapy, p. 987, 1978
  • Maigaard, S., Frimodt-Møller, N. & Madsen, P. P.: Comparison of netilmicin and amikacin in treatment of complicated urinary tract infections. Antimicrob Agents Chemother 14: 544, 1978
  • Siersbaeck-Nielsen, K., Mölholm Hansen, J., Kampmann, J. & Kristensen, M.: Rapid evaluation of creatinine clearance. Lancet 1: 1133–1134, 1971
  • Welling, P. G., Baumueller, A., Lau, C. C. & Madsen, P. O.: Netilmicin pharmacokinetics after single intravenous doses to elderly male patients. Antimicrob Agents Chemother 12: 328, 1977

References

  • Alfthan, O., Renkonen, O. & Haeger, K.: Netilmicin therapy in patients with complicating gram-negative urinary tract infection. Clinical Trials Journal 15: no. 2, 1978
  • Brodey, M. V., Bundtzen, R. & Craig, W.: Comparative efficacy and toxicity of gentamicin and netilmicin in serious gram-negative infections. 11th Int. Congress of Chemotherapy. Abstract no. 674.
  • Cox, C. E.: Double blind comparison of netilmicin and gentamicin in the treatment of bacteriaemia associated with genito-urinary tract infections. 11th Int. Congress of Chemotherapy. Abstract no. 675.
  • Falisevac, J., Schønwald, S., Car, V., Genojmicki, B. & Stritof, M.: Clinical experience with netilmicin. 11th Int. Congress of Chemotherapy. Abstract no. 671.
  • Henriksson, P., Svenningsen, N., Juhlin, I. & Haeger, K.: Netilmicin in moderate to severe infections in neonates and infants. To be published.
  • Information brochure on netilmicin. Schering Corp 1976
  • Jonsson, M., Julander, I., Tunewall, G. & Haeger, K. Netilmicin treatment of serious infections in patients with renal insufficiency. Int Med Res. 6: 226, 1978
  • Rahal, J. J.: Bacterial efficacy of Sch. 20569 and amikacin against gentamicin sensitive and resistant organisms. Antimicrob Agents Chemother 9: 595, 1976
  • Rosdahl, V. T., Vejlsgaard, V., Rosdahl, N. & Vejlsgaard, R.: A micromethod for determination of antibiotics in serum. Dan Med Bull 16: 133, 1969
  • Solberg, C. O., Madsen, S., Digranes, A., Stokstad, S., Hellum, K., Halvorsen, F. & Bakke, K. High dose netilmicin therapy, efficacy, tolerance and tissue penetration. 11th Int. Congress of Chemotherapy. Abstract no. 672.
  • Vesterhauge, S., Johnsen, N. J., Thomsen, J. & Svare, J.: Netilmicin treatment followed by monitoring of vestibular and auditory function, using highly sensitive methods. Scand J Infect Dis, Suppl. 23: 117, 1980

References

  • Alfthan, O., Renkonen, O.-V. & Haeger, K.: Netilmicin therapy in patient with complicating gram-negative tract infections. Clin Trials J 15: 55, 1978
  • Doolan, P. D., Alpen, E. L. & Theil, G. B.: A clinical appraisal of the plasma concentration and endogenous clearance of creatinine. Amer J Med 32: 65, 1962
  • Edén, T., Skånsberg, P. & Haeger, K.: Netilmicin in severe infections: A randomized comparison with Gentamycin. Curr Ther Res 24: 96, 1978
  • Ericsson, H. M. & Sherris, J. C.: Antibiotic sensitivity-testing. Acta Pathol Microbiol Scand (B), Suppl. 217, 1971
  • Frimodt-Møller, N., Maigaard, S. & Madsen, P. O.: Netilmicin treatment of complicated urinary tract infection in patients with renal function impairment. Antimicrob Agents Chemother 16: 406, 1979
  • Hagström, G. L., Luft, S. C., Nahm Yum, M., Sloan, R. S. & Maxwell, D. R.: Nephrotoxicity of Netilmicin in combination with non aminoglycoside antibiotics. Antimicrob Agents Chemother 13: 490, 1978
  • Henriksson, P., Svenningsen, N., Juhlin, I. & Haeger, K.: Netilmicin in moderate to severe infections in neonates and infants. Scand J Infect Dis, Suppl 23: 155, 1980
  • Hewitt, W. L.: Gentamicin: Toxicity in perspective. Postgrad Med J 50: Suppl 7: 55, 1974
  • Hodson, C. J.: Discussion on pyelonephritis. The radiological diagnosis of pyelonephritis. Proc Roy Soc Med 52: 669, 1959
  • Jonsson, M., Julander, I., Thunevall, E. & Haeger, K.: Netilmicin treatment of serious infections in patients with renal insufficiency. J Int Med Res 6: 226, 1978
  • Jonsson, M. & Hæger, K.: Nuläget för amino-glykosiderna. Läkartidningen 1980, to be published. (In Swedish.)
  • Juhlin, I.: Compiled data on Netilmicin susceptibility of bacterial strains. Scand J Infect Dis., Suppl 23: 39, 1980
  • Kahlmeter, G., Jonsson, S. & Kamme, C.: Multiple-compartment pharmacokinetics of tobramycin. J Antimicrob Chemother 4 ( Suppl. A): 5, 1978
  • Luft, F. C.: Netilmicin: A review of toxicity in laboratory animals. J Int Med Res 6: 286, 1978
  • Nordström, L., Christensson, P., Haeger, K., Juhlin, I., Tjernström, O. & Wallmark, E.: Netilmicin: Clinical evaluation of efficacy and toxicity of a new aminoglycoside. J Int Med Res 7: 117, 1979
  • Panwalker, A. P., Malow, J. B., Zimelis, V. M. & Jackson, G. G.: Netilmicin: Clinical efficacy, tolerance and toxicity. Antimicrob Agents Chemother 13: 170, 1978
  • Solberg, C. O., Tschudi Madsen, S., Digranes, A., Stockstad, S., Hellum, K. B., Halvorsen, F. J. & Bakke, K.: High dose netilmicin therapy: Efficacy, tolerance and tissue penetration. J Antimicrob Chemother 6: 133, 1980
  • Tjernström, Ö.: Prospective evaluation of vestibular and auditory function in the treatment of 76 patients with a new aminoglycoside antibiotic, Netilmicin. Scand J Infect Dis, Suppl 23: 122, 1980
  • Trestman, I., Parsons, J., Santoro, J., Goodhart, G. & Kaye, D.: Pharmacology and efficacy of Netilmicin. Antimicrob Agents Chemother 13: 832, 1978
  • Örsten, P. Å.: Asymmetry of renal function. Acta Med Scand, Suppl. 447, 1966

References

  • Adler, S. M. & Denton, R. L.: The erythrocyte sedimentation rate in the newborn period. J Pediat 86: 942, 1975
  • Boyle, R. J., Chandler, B. D., Stonestreet, B. S. & Oh, W.: Early identification of sepsis in infants with respiratory distress. Pediatrics 62: 744, 1978
  • Böttinger, E. L. & Svedberg, C. A.: Normal erythrocyte sedimentation rate and age. Brit Med J 11: 85, 1967
  • Davies, P. A.: Bacterial infection in the foetus and newborn. Arch Dis Child 46: 1, 1971
  • Editorial: Neonatal bacteriaemia: Diagnosis and management. Brit Med J II: 1385, 1979
  • Fåhræus, R.: The suspension stability of the blood. Acta Med Scand 55: 1, 1921
  • Ibsen, K. Kaas & Kirk, L.: Sænkningsreaktion og behandling med neuroleptika. Ugeskr Læg 136: 1572, 1974
  • Lascari, A.: The erythrocyte sedimentation rate. Pediatr Clin North Am 19: 1115, 1972
  • Page, L. B. & Culver, P. J.: A syllabus of laboratory examinations in clinical diagnosis. 2nd ed. Harvard University Press, Cambridge, 1962
  • Westergren, A.: Studies of the suspension stability of the blood in pulmonary tuberculosis. Acta Med Scand 54: 247, 1921

References

  • Alfthan, O., Renkonen, O.-V. & Haeger, K.: Netilmicin therapy in patients with complicating gram-negative urinary tract infections. Clin Trials J 15: 55, 1978
  • Bergan, T. & Michalsen, H.: Pharmacokinetic assessment of netilmicin in newborns and older children. In press.
  • Briedis, D. J. & Robson, H. G.: Comparative activity of netilmicin, gentamicin, amikacin, and tobramycin against Pseudomonas aeruginosa and Enterobacteriaceae. Antimicrob Agents Chemother 10: 592, 1976
  • Chiu, P. J. S., Miller, G. H., Brown, A. D., Long, J. F. & Waitz, J. A.: Renal pharmacology of netilmicin. Antimicrob Agents Chemother 11: 821, 1977
  • Fu, K. P. & Neu, H. C.: In vitro studies of netilmicin compared with other aminoglycosides. Antimicrob Agents Chemother 10: 626, 1976
  • Henriksson, P., Svenningsen, N., Juhlin, I. & Haeger, K.: Netilmicin in moderate to severe infections in neonates and infants: A study of efficacy, tolerance and pharmacokinetics. Curr Ther Res 24: 108, 1978
  • Jonsson, M., Julander, I., Tunevall, G. & Haeger, K.: Netilmicin treatment of serious infections in patients with renal insufficiency. J Int Med Res 6: 226, 1978
  • Kabins, S. A., Nathan, C. & Cohen, S.: In vitro comparison of netilmicin, a semisynthetic derivative of sisomycin, and four other aminoglycoside antibiotics. Antimicrob Agents Chemother 10: 139, 1976
  • Luft, F. L., Yum, M. N. & Kleit, S. A.: Comparative nephrotoxicities of netilmicin and gentamicin in rats. Antimicrob Agents Chemother 10: 845, 1976
  • Rahal, J. J., Simberkoff, M. S., Kagan, K. & Moldover, N. H.: Bactericidal efficacy of Sch 20569 and amikacin against gentamicin-sensitive and -resistant organisms. Antimicrob Agents Chemother 9: 595, 1976
  • Watanakunakorn, C.: Comparative in vitro activity of Sch 20656, netilmicin, gentamicin, and tobramycin. Antimicrob Agents Chemother 10: 382, 1976
  • Wersäll, J. & Björkroth, B.: Netilmicin, an aminoglycoside with low ototoxicity in animal experiments. 10th Intern Congr Chemother, Zürich, Switzerland, Abstract no. 329, 1977
  • McCracken, G. H., Jr. & Nelson, J. D.: Antimicrobial therapy for newborns. Grune & Stratton, New York, 1977

References

  • Brown, K. N., Benedictson, J. & Swanby, S.: In vitro comparison of gentamycin, tobramicin, sisomicin and netilmicin. Antimicrob Agents Chemother 10: 768, 1976
  • Buchwold, F. J., Ronald, A. R., Lank, B. A., Fox, L., Harding, G. K. M. & Gurwith, M. J.: Clinical trial of netilmicin. Curr Chemother, 984, 1978. Amer. Soc. Microbiol., Washington
  • Edelstein, P. H. & Meyer, R. D.: Netilmicin therapy of serious Gram-negative bacillary infections. Curr Chemother, 982, 1978. Amer. Soc. Microbiol., Washington
  • Edén, T., Skånsberg, P. & Haeger, K.: Netilmicin in severe infections: A randomized comparison with gentamicin. Curr Ther Res 24: 96, 1978
  • Eichoff, T. C., Klein, J. D. & Daly, A. K.: Neonatal sepsis and other infections due to group B beta-hemolytic streptococci. N Engl J Med 271: 1221, 1964
  • Frame, P. T., Watanakunakorn, C. & Cluxton, R. J., Jr: Comparative nephrotoxicity of netilmicin and gentamicin in rabbits. Curr Ther Res 24: 344, 1978
  • Fu, K. P. & Neu, H. C.: In vitro synergistic effect of netilmicin, a new aminoglycoside antibiotic. Antimicrob Agents Chemother 10: 511, 1976
  • Geraci, J. E.: Antibiotic therapy of bacterial endocarditis. Heart Bull 12: 90, 1963
  • Henriksson, P., Svenningsen, N., Juhlin, I. & Haeger, K.: Netilmicin in moderate to severe infections in neonates and infants. Curr Ther Res 24: 108, 1978
  • Luft, F. C., Yum, M. N. & Kleit, S. A.: Comparative nephrotoxicity of netilmicin and gentamicin in rats. Antimicrob Agents Chemother 10: 845, 1976
  • Miller, G. H., Arcieri, G., Weinstein, M. J. & Waitz, J. A.: Biological activity of netilmicin, a broad-spectrum semisynthetic aminoglycoside antibiotic. Antimicrob Agents Chemother 10: 827, 1976
  • Rahal, J. J.: Bacterial efficacy of netilmicin and amikacin against gentamicin-sensitive and resistant organisms. Antimicrob AGents Chemother 9: 595, 1976
  • Rosdahl, V. T., Vejlsgaard, V., Rosdahl, N. & Vejlsgaard, R.: A micromethod for determination of antibiotics in serum. Dan Med Bull 16: 133, 1969
  • Siegel, J.: Pharmacokinetic properties of netilmicin in newborn infants. Antimicrob Agents Chemother 15: 246, 1979
  • Soussy, C. J. & Duval, J.: Activité antibactérienne comparée de sept aminosides. Med Mal Infect 6: 211, 1976

References

  • Ericsson, H. M. & Sherris, J. C.: Antibiotic sensitivity testing. Report of an international collaborative study. Acta Pathol Microbiol Scand (B), Suppl. 217, 1971
  • Henriksson, P., Svenningsen, N., Kahlmeter, G. & Haeger, K.: Sisomicin treatment of serious neonatal infections. A clinical and pharmacokinetic study. Acta Paediatr Scand 66: 317, 1977
  • Jonsson, M., Julander, O., Tunevall, G. & Haeger, K.: Netilmicin treatment of serious infections in patients with renal insufficiency. J Int Med Res 6: 226, 1978
  • Luft, F. C., Yum, M. N. & Kleit, S. A.: Comparative nephrotoxicity of netilmicin and gentamicin in rats. Antimicrob Agents Chemother 10: 845, 1976
  • Marks, M. I., Hammerberg, S., Greenstone, G. & Silver, B.: Activity of newer aminoglycosides and carbenicillin, alone and in combination, against gentamicin-resistant Pseudomonas aeruginosa. Antimicrob Agents Chemother 10: 399, 1976
  • McCracken, G. H. & Echinwald, H. F.: Antimicrobial therapy: Therapeutic recommendations and a review of the newer drugs. J Pediatr 85: 451, 1974
  • McCracken, G. H. & Nelson, J. D.: Antimicrobial therapy for newborns. Practical application of pharmacology to clinical usage. Monographs in Neonatology, Grune & Stratton, New York 1977
  • Moellering, R. C., Jr, Wennersten, C. & Weinstein, A. J.: Penicillin-Tobramycin synergism against Enterococci: A comparison with penicillin and gentamicin. Antimicrob Agents Chemother 13: 526, 1973
  • Rosdahl, N. & Frölund-Thomsen, V.: In vitro activity of gentamicin, alone and in combination with other antibiotics. Acta Pathol Microbiol Scand (B) 79: 333, 1971

References

  • Barza, M., Pinn, V., Tanguay, P. & Murray, T.: Nephrotoxicity of newer cephalosporins and aminoglycosides alone and in combination in a rat model. J Antimicrob Chemother 4 ( Suppl. A): 59, 1978
  • Bodey, G. P.: Infections in cancer patients. Current Treatment Reviews 2: 89, 1975
  • Feld, R., Valdivieso, M., Bodey, G. P. & Rodriguez, V.: A comparative trial of sisomicin therapy by intermittent versus continuous infusion. Am J Med Sci 274: 179, 1977
  • Gaya, H., Klastersky, J. & Schimpff, S. C.: Nephrotoxicity during combined treatment with gentamicin and cephalothin. Fifteenth Interscience Conference on Antibiotics and Chemotherapy, Washington, 1975, Abstract 401.
  • Rodrigues, V. & Bodey, G. P.: Antibacterial therapy—special considerations in neutropenic patients. Clin Haematol 5: 347, 1976
  • Schimpff, S. C., Greene, W. H., Young, V. M. & Wiernik, P. H.: Europ J Cancer 9: 440, 1973
  • Winston, D. J., Gale, R. P., Meyer, D. V. & Young, L. S.: Infectious complications of human bone marrow transplantation. Medicine 58: 1, 1979

References

  • Jackson, G. G.: Present status of aminoglycosides antibiotics and their safe, effective use. Clin Therap 1: 200, 1977
  • Jackson, G. G.: The Toxicity of Antibiotic Combinations. In: Antibiotic interactions (ed. J. D. Williams), pp. 151–170, Academic Press, London 1979
  • Jackson, G. G. & Riff, L. J.: Pseudomonas bacteremia. Pharmacologic and other bases for failure of treatment with gentamicin. J Infect Dis 124 ( S): 185, 1971
  • Kreger, B. E., Craven, D. E. & McCabe, W. R.: Gram-negative bacteremia. IV. Reevaluation of clinical features and treatment in 612 patients. Am J Med Mar 1980 (personal communication)
  • McCabe, W. R. & Jackson, G. G.: Gram-negative bacteremia. II. Clinical, laboratory and therapeutic observations. Arch Int Med 110: 856, 1962
  • Moellering, R. C., Jr, Murray, B. L., Schoenbaum, S. C., Adler, J. & Wennersten, C. B.: A novel mechanism of resistance to penicillin—gentamicin synergism in Streptococcus fecalis. J Infect Dis 141: 81, 1980
  • Panwalker, A. P., Malow, J. P., Zimelis, V. M. & Jackson, G. G.: Netilmicin: Clinical efficacy, tolerance and toxicity. Antimicrob Agents Chemother 13: 170, 1978
  • The EORTC International Antimicrobial Therapy Project Group. Three antibiotic regimens in the treatment of infection in febrile granulocytopenic patients with cancer. J Infect Dis 137: 14, 1978

References

  • Bodey, G. P., Buckley, M., Sathe, Y. S. & Freireich, E.: Quantitative relationships between circulating granulocytes and infections in patients with acute leukemia. Ann Int Med 64: 328, 1966
  • Brodey, M. V., Bundtzen, R. W. & Craig, W. A.: Comparative efficacy and toxicity of netilmicin and gentamycin in serious Gram-negative infections. 11th International Congress of Chemotherapy 1979. Abstracts No. 674.
  • Cox, C. E.: Double-blind comparison of netilmicin and gentamycin in the treatment of bacteraemia associated with genitourinary tract infections. 11th International Congress of Chemotherapy, 1979, Abstracts No. 675.
  • The EORTC International Therapy Project Group: Three antibiotic regimens in the treatment of infection in febrile granulocytopenic patients with cancer. J Inf Dis 137, 1: 14, 1978
  • Garrod, L. P.: On antimicrobial activity. In: Gentamycin: Review and commentary on selected world literature, p. 11 (ed. G. G. Jackson). Schering Corp., New Jersey 1974
  • Jonsson, M., Julander, I., Tunevall, G. & Haeger, K.: Netilmicin treatment of serious infections in patients with renal insufficiency. J Int Med Res 6: 226, 1978
  • Justesen, T.: A rapid micro-assay of gentamycin, kanamycin or streptomycin in serum containing penicillins or cephalosporins. Acta Pathol Microbiol Scand (B), Suppl. 241: 111, 1973
  • Mortensen, B. T., Mortensen, N. & Nissen, N. I.: Clinical experience with bacteraemia in patients with leukaemia and allied neoplastic diseases. Chemotherapy 24: 179, 1978
  • Mørk Hansen, M. & Kaaber, K.: Nephrotoxicity in combined cephalothin and gentamycin therapy. Acta Med Scand 201: 463, 1977
  • Rosdahl, V. T., Vejlsgaard, V., Rosdahl, N. & Vejlsgaard, R.: A micromethod for determination of antibiotics in serum. Dan Med Bull 16: 133, 1969
  • Sanford, J. P.: On septicemia. In: Gentamycin: Review and commentary on selected world litterature, pp. 115–117 (ed. G. G. Jackson). Schering Corp, New Jersey 1974
  • Schering Corp.: Investigational brochure on netilmicin. New Jersey 1976
  • Weissenbacher, E. R.: A double-blind comparison of netilmicin and gentamycin in the treatment of obstetric-gynecological infections. 11th International Congress of Chemotherapy 1979. Abstracts. No. 673.
  • Winkel, O., Mørk Hansen, M., Kaaber, K. & Rozarth, K.: A prospective study of gentamycin ototoxicity. Acta Otolaryngol 86: 212, 1978

References

  • Alfthan, O., Renkonen, O. V. & Haeger, K.: Netilmicin therapy in patients with complicating Gram-negative urinary tract infections. Clin Trial J 15: 55, 1978
  • Edén, T., Skånsberg, P. & Haeger, K.: Netilmicin in severe infections: A randomized comparison with gentamicin. Curr Ther Res 24: 1978
  • Ericsson, H. M. & Sherris, J. C.: Antibiotic sensitivity testing. Report of an international collaborative study. Acta Pathol Microbiol Scand, Section B, Suppl. 217, 1971
  • Jonsson, M., Julander, I., Tunevall, G. & Haeger, K.: Netilmicin treatment of serious infections in patients with renal insufficiency. J Int Med Res 6: 226, 1978
  • Luft, F. C.: Netilmicin: A review of toxicity in laboratory animals. J Int Med Res 6: 286, 1978
  • Maigaard, S., Frimodt-Möller, N. & Madsen, P. O.: Comparison of netilmicin and amikacin in treatment of complicated urinary tract infections. Antimicrob Agents Chemother 14: 544, 1978
  • Panwalker, A. P., Malow, J. B., Zimelis, V. M. & Jackson, G. G.: Netilmicin: Clinical efficacy, tolerance, and toxicity. Antimicrob Agents Chemother 13: 170, 1978

References

  • Cowan, S. T. & Steel, K. J.: Manual for the identification of medical bacteria. Cambridge University Press, London 1974
  • Holdeman, L. V. & Moore, W. E. C.: Anaerobic laboratory manual of the Virginia Polytechnic Institute, Blacksburg, Virginia 1975
  • Noone, P., Pattison, J. R. & Slack, R. C. B.: A simple, rapid assay for the measurement of antibiotic concentrations. In: Human serum in some methods for microbiological assay, Technical Series 8, p. 153 (ed. R. G. Board & D. W. Lovelock). Academic Press, London 1975
  • Noone, P., Pattison, J. R. & Garfield-Davies, D.: The effective use of gentamicin in life-threatening sepsis. Postgrad Med J 50: ( Suppl. 7) 9, 1974

References

  • Alfthan, O., Renkonen, O.-V. & Haeger, K.: Netilmicin therapy in patients with complicating Gram-negative urinary tract infections. Clin Trials J 15: 55, 1978
  • Bennett, J. V., Brodie, L. J., Benner, E. J. & Kirby, W. M. M.: Simplified, accurate method for antibiotic assay of clinical specimens. Appl Microbiol 14: 170, 1966
  • Bowmann, R. L., Silverblatt, F. J. & Kaloyanides, G. J.: Comparison of the nephrotoxicity of netilmicin and gentamicin in rats. Antimicrob Agents Chemother 12: 474, 1977
  • Dahlgren, J. G., Anderson, E. T. & Hewitt, W. L.: Gentamicin blood levels: A guide to nephrotoxicity. Antimicrob Agents Chemother 8: 58, 1975
  • Digranes, A., Østervold, B., Madsen, S. T., Solberg, C. O. & Haeger, K.: Susceptibility of 327 clinical isolates to netilmicin. J Int Med Res 6: 409, 1978
  • Eickhoff, T. C. & Ehret, J. M.: In vitro activity of netilmicin compared with gentamicin, tobramycin, amikacin and kanamycin. Antimicrob Agents Chemother 11: 791, 1977
  • Ericsson, H. M. & Sherris, J. C.: Antibiotic sensitivity testing. Report of an international collaborative study. Acta Path Microbiol Scand (B) 217 ( Suppl.), 1971
  • Fu, K. P. & Neu, H. C.: In vitro study of netilmicin compared with other aminoglycosides. Antimicrob Agents Chemother 10: 526, 1976
  • Hellum, K. B., Schreiner, A., Digranes, A. & Bergman, I.: Skin blisters produced by suction: A new model for studies of penetration of antibiotics in humans. In: Current Chemotherapy, Proceedings of the 10th International Congress of Chemotherapy, p. 620 (ed. W. Siegenthaler & R. Lüthy). American Society for Microbiology, Washington D.C. 1978
  • Hewitt, W. L.: Gentamicin: Toxicity in perspective. Postgrad Med J 50 ( Suppl. 7): 55, 1974
  • Jackson, G. G. & Arcieri, G.: Ototoxicity of gentamicin in man: A survey and controlled analysis of clinical experience in the United States. J Infect Dis 124 ( Suppl.): S130, 1971
  • Jonsson, M., Julander, I., Tunevall, G. & Haeger, K.: Netilmicin treatment of serious infections in patients with renal insufficiency. J Int Med Res 6: 226, 1978
  • Kabins, S. A., Nathan, C. & Cohen, S.: In vitro comparison of netilmicin, a semisynthetic derivative of sisomicin, and four other aminoglycoside antibiotics. Antimicrob Agents Chemother 10: 139, 1976
  • Klastersky, J., Meunier-Carpentier, F., Coppens-Kahan, L., Daneau, D. & Prevost, J. M.: Clinical and bacteriological evaluation of netilmicin in Gram-negative infections. Antimicrob Agents Chemother 12: 503, 1977
  • Luft, F. C., Yum, M. N. & Kleit, S. A.: Comparative nephrotoxicities of netilmicin and gentamicin in rats. Antimicrob Agents Chemother 10: 845, 1976
  • Meyers, R. M.: Ototoxic effects of gentamicin. Arch Otolaryngol 92: 160, 1970
  • Miller, G. H., Arcieri, G., Weinstein, M. J. & Waitz, J. A.: Biological activity of netilmicin, a broad spectrum semisynthetic aminoglycoside antibiotic. Antimicrob Agents Chemother 10: 827, 1976
  • Panwalker, A. P., Malow, J. B., Zimelis, V. M. & Jackson, G. G.: Netilmicin: Clinical efficacy, tolerance, and toxicity. Antimicrob Agents Chemother 13: 170, 1978
  • Solberg, C. O. & Schreiner, A.: Gentamicin therapy of severe infections. Acta Path Microbiol Scand (B) 81 ( Suppl. 241): 164, 1973
  • Trestman, I., Parsons, J., Santoro, J., Goodheart, G. & Kaye, D.: Pharmacology and efficacy of netilmicin. Antimicrob Agents Chemother 13: 832, 1978

References

  • Alfthan, O., Renkonen, O.-V. & Haeger, K.: Netilmicin therapy in patients with complicating Gram-negative urinary tract infections. Clin Trial J 15: 55, 1978
  • Bang, J. & Mortensen, I.: In vitro comparison of gentamicin and netilmicin including a regression line for netilmicin. Scand J Infect Dis, Suppl. 23: 34, 1980
  • Bergan, T. & Michalsen, H.: Pharmacokinetics of netilmicin in newborns. Personal communication
  • Bowman, R. L., Silverblatt, F. J. & Kaloyanides, G. J.: Comparison of the nephrotoxicity of netilmicin and gentamicin in rats. Antimicrob Agents Chemother 12: 474, 1977
  • Brandenhoff, P., Stafanger, G., Gammelgaard, P. A., Rasmussen, F., Holm-Jensen, S., Bretlau, P. & Frølund Thomsen, V.: Netilmicin therapy of patients with septicaemia and other severe infections. Preliminary results. Scand J Infect Dis, Suppl. 23: 181, 1980
  • Briedis, D. & Robeson, H. G.: Comparative activity of netilmicin, gentamicin, amikacin, and tobramycin against Pseudomonas aeruginosa and Enterobacteriaceae. Antimicrob Agents Chemother 10: 592, 1976
  • Brown, K. N., Benetictson, J. & Swanby, S.: In vitro comparison of gentamicin, tobramycin, sisomicin, and netilmicin. Antimicrob Agents Chemother 10: 768, 1976
  • Chiu, P. J. S., Miller, G. H., Brown, A. D., Long, J. F. & Waitz, J. A.: Renal pharmacology of netilmicin. Antimicrob Agents Chemother 11: 821, 1977
  • Dahlager, J. I.: The effect of netilmicin and other aminoglycosides on renal function. A survey of the literature on the nephrotoxicity of netilmicin. Scand J Infect Dis, Suppl. 23: 96, 1980
  • Denneberg, T., Haeger, K. & Juhlin, I.: Netilmicin therapy of serious renal and urinary tract infections in patients with normal and impaired renal function. Scand J Infect Dis, Suppl. 23: 135, 1980
  • Digranes, A. & Dibb, W. L.: The in vitro activity of netilmicin against 357 clinical isolates of Enterobacteriaceae, Pseudomonas aeruginosa and Staphylococcus aureus. Scand J Infect Dis, Suppl. 23: 30, 1980
  • Digranes, A. Østervold, B., Madsen, S. T., Solberg, C. O. & Haeger, K.: Susceptibility of 327 clinical isolates to netilmicin. J Int Med Res 6: 409, 1978
  • Eickhoff, T. C. & Ehret, J. M.: In vitro activity of netilmicin compared with gentamicin, tobramycin, amikacin, and kanamycin. Antimicrob Agents Chemother 11: 791, 1977
  • Fu, K. P. & Neu, H.: In vitro study of netilmicin compared with other aminoglycosides. Antimicrob Agents Chemother 10: 526, 1976
  • Geddes, A. M.: The compromised host and antibacterial treatment. Scand J Infect Dis, Suppl. 23: 161, 1980
  • Geisler, C., Mørk Hansen, M. & Mortensen, N.: Netilmicin therapy of patients with leukemia and malignant lymphoma. Scand J Infect Dis, Suppl. 23: 176, 1980
  • Hellum, K. B., Madsen, S. T., Digranes, A., Stokstad, S. & Solberg, C. O.: High-dose netilmicin therapy of severe or chronic infections. Scand J Infect Dis, Suppl. 23: 189, 1980
  • Henriksson, P., Svenningsen, N., Juhlin, I. & Haeger, K.: Netilmicin in moderate to severe infections in newborns and infants. A study of efficacy, tolerance and pharmacokinetics. Scand J Infect Dis, Suppl. 23: 155, 1980
  • Herting, R. L., Lane, A. Z. & Lorber, R. R.: Netilmicin—Chemical development and overview of clinical research. Scand J Infect Dis, Suppl. 23: 20, 1980
  • Jackson, G. G.: Present status of aminoglycoside antibiotics and their safe, effective use. Clinical therapeutics 1: 200, 1977
  • Jackson, G. G.: Clinical assessment of newer antibiotics. Effect in compromised hosts and drug combinations. Scand J Infect Dis, Suppl. 23: 167, 1980
  • Jonsson, M. & Haeger, K.: Aminoglycosides—the current situation. In press.
  • Juhlin, I. & Tunevall, G.: Compiled data on aminoglucoside, foremost netilmicin susceptibility of bacterial strains. Scand J Infect Dis, Suppl. 23: 39, 1980
  • Kabins, S. A., Nathan, C. & Cohen, S.: In vitro comparison of netilmicin, a semisynthetic derivative of sisomicin, and four other aminoglycosid antibiotics. Antimicrob Agents Chemother 10: 139, 1976
  • Kahlmeter, G.: Netilmicin—clinical pharmacokinetics and aspects on dosage schedules. An overview. Scand J Infect Dis, Suppl. 23: 74, 1980
  • Kallings, L. O.: Resistance factors: Influence on netilmicin activity. Scand J Infect Dis, Suppl. 23: 54, 1980
  • Klastersky, J., Meunier-Carpentier, F., Coppens-Kahan, L., Daneau, D. & Prevost, J. M.: Clinical and bacteriological evaluation of netilmicin in gram-negative infections. Antimicrob Agents Chemother 12: 503, 1977
  • Luft, F. C.: The nephrotoxic potential of netilmicin as determined in a rat model. Scand J Infect Dis, Suppl. 23: 82, 1980
  • Luft, F. C., Yum, M. N. & Kleit, S. A.: Comparative nephrotoxicities of netilmicin and gentamicin. Antimicrob Agents Chemother 10: 845, 1976
  • Madsen, P. O., Baumueller, A., Frimodt-Møller, N., Hoyme, K., Lau, C., Maigaard, S., Nielsen, O. S. & Welling, P. G.: Netilmicin treatment of complicated urinary tract infections. Scand J Infect Dis, Suppl. 23: 128, 1980
  • Meyer, R. D., Kraus, L. L. & Pasiecznik, K. A.: In vitro susceptibility of gentamicin-resistant Enterobacteriaceae and Pseudomonas aeruginosa to netilmicin and selected aminoglycoside antibiotics. Antimicrob Agents Chemother 10: 677, 1976
  • Meyers, B. M. & Hirschman, S. Z.: Antimicrobial activity in vitro of netilmicin and comparison with sisomicin, gentamicin and tobramycin. Antimicrob Agents Chemother 11: 118, 1977
  • Miller, G. H., Hare, R. S., Moss, Jr, E. L., Sabatelli, F. J., Schafer, T. W. & Waitz, J. A.: Evaluation of netilmicin susceptibility discs using bacteria with known aminoglycoside resistance patterns: Correlation of in vitro and in vivo test results. Scand J Infect Dis, Suppl. 23: 62, 1980
  • Miller, G. H., Arcieri, G., Weinstein, M. J. & Waitz, J. A.: Biological activity of netilmicin, a broad-spectrum semisynthetic aminoglycoside antibiotic. Antimicrob Agents Chemother 10: 827, 1976
  • Mortensen, I.: Combined effect of benzylpenicillin and gentamicin/netilmicin on Streptococcus faecalis. Scand J Infect Dis, Suppl. 23: 59, 1980
  • Nielsen, M., Kaas Ibsen, K., Prag, J. Hørlyk, H., Vrang, C., Korner, B. & Peitersen, B.: The value of the microerythrocyte sedimentation rate in the diagnosis of infections in newborns. Scand J Infect Dis, Suppl. 23: 143, 1980
  • Nordbring, F.: Clinical review of the aminoglycosides. Scand J Infect Dis, Suppl. 23: 15, 1980
  • Panwalker, A. P., Malow, J. B., Zimelis, V. M. & Jackson, G. G.: Netilmicin: Clinical efficacy, tolerance, and toxicity. Antimicrob Agents Chemother 13: 170, 1978
  • Peitersen, B., Korner, B. & Peitersen, E.: Netilmicin, efficacy and tolerance in the treatment of systemic infections in neonates. Scand J Infect Dis, Suppl. 23: 151, 1980
  • Peitersen, E.: The influence of examination technique and patient status on aminoglycoside toxicity. Scand J Infect Dis, Suppl. 23: 114, 1980
  • Perera, M. R., Amirak, I. D. & Noone, P.: Netilmicin 200 mg twice a day for adult patients with life threatening infections. Scand J Infect Dis, Suppl. 23: 186, 1980
  • Phillips, I., Smith, A. & Shannon, K.: Antibacterial activity of netilmicin, a new aminoglycoside antibiotic, compared with that of gentamicin. Antimicrob Agents Chemother 11: 402, 1977
  • Rahal, J. J., Jr, Simberkoff, M. J., Kagan, K. & Moldover, N. H.: Bactericidal efficacy of Sch 20569 and amikacin against gentamicin-sensitive and -resistant organisms. Antimicrob Agents Chemother 9: 595, 1976
  • Rankin, L. I., Luft, F. C., Yum, M. N., Sloan, R. S., Dinwiddie, C. B., Jr & Isaacs, L. L.: Comparative nephrotoxicity of Sch 21420 and amikacin in rats. Antimicrob Agents Chemother 16: 491, 1979
  • Riff, L. & Moreschi, G.: Netilmicin and gentamicin: Comparative pharmacology in humans. Antimicrob Agents Chemother 11: 609, 1977
  • Sanders, C. C.: Synergy of penicillin-netilmicin combinations against enterococci including strains highly resistant to streptomycin or kanamycin. Antimicrob Agents Chemother 12: 195, 1977
  • Schering Corporation: Netilmicin sulfate injection. Schering Corp., Bloomfield, N. J., June 1978 (Vol 1.)
  • Solberg, C. O., Madsen, S. T., Digranes, A., Stokstad, S., Hellum, K. B., Halvorsen, F. J. & Bakke, K.: High-dose netilmicin therapy of patients with septicaemia and pyelonephritis. Proceedings of the 11th international congress of chemotherapy and 19th interscience conference on antimicrobial agents and chemotherapy. Amer Soc Microbiol, Boston, 1980, pp. 378–380.
  • Solberg, C. O., Madsen, S. T., Digranes, A., Stokstad, S., Hellum, K. B., Halvorsen, F. J. & Bakke, K.: High-dose netilmicin therapy: Efficacy, tolerance and tissue penetration. J Antimicrob Chemother 6: 133, 1980
  • Svare, J., Johnsen, N. J., Vesterhauge, S., Lund, F., Thomsen, J. & Vejlsgaard, R.: Netilmicin in urinary tract infections. Scand J Infect Dis, Suppl. 23: 132, 1980
  • Thompson, W. L.: Aminoglycoside nephrotoxicity in dogs: Influence of drug and dosage regimen. Scand J Infect Dis, Suppl. 23: 91, 1980
  • Tjernström, Ö.: Prospective evaluation of vestibular and auditory function in 76 patients treated with netilmicin. Scand J Infect Dis, Suppl. 23: 122, 1980
  • Trestman, I., Parsons, J., Santoro, J., Goodhart, G. & Kaye, D.: Pharmacology and efficacy of netilmicin. Antimicrob Agents Chemother 13: 832, 1978
  • Vesterhauge, S., Johnsen, N. J., Thomsen, J. & Svare, J.: Netilmicin treatment followed by monitoring of vestibular and auditory function, using highly sensitive methods. Scand J Infect Dis, Suppl. 23: 117, 1980
  • Watanakunakorn, C.: Comparative in vitro activity of SCH 20656, netilmicin, gentamicin, and tobramycin. Antimicrob Agents Chemother 10: 382, 1976
  • Welling, P. G., Baumueller, A., Lan C. C. & Madsen, P. O.: Netilmicin pharmacokinetics after single intravenous doses to elderly male patients. Antimicrob Agents Chemother 12: 328, 1977
  • Wersäll, J.: The ototoxic potential of netilmicin compared with amikacin. An animal study in guinea pigs. Scand J Infect Dis, Suppl. 23: 117, 1980

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.