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Scandinavian Journal of Infectious Diseases Volume 15, 1983 - Issue 3
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Main Article

Influence of Doxycycline on the Normal Human Flora and Colonization of the Oral Cavity and Colon

Anders Heimdahl Department of Oral Surgery and Microbiology, Huddinge University Hospital, Karolinska Institute, and the National Bacteriological Laboratory, Stockholm, Sweden
&
Carl Erik Nord Department of Oral Surgery and Microbiology, Huddinge University Hospital, Karolinska Institute, and the National Bacteriological Laboratory, Stockholm, Sweden
Pages 293-302 | Published online: 02 Jan 2015

References

  • . Alestig K. Studies on the intestinal excretion of doxycycline. Scand J Infect Dis 6: 265, 1974.
  • . Alestig K, Lidin-Janson G. The effect of doxycycline and tetracycline hydrochloride on the aerobic fecal flora. Scand J Infect Dis 7: 265, 1975.
  • . Bartlett JG, Bustetter LA, Gorbach SL, Onderdonk A. Comparative effect of tetracycline and doxycycline on the occurrence of resistant Escherichia coli in the fecal flora. Antimicrob Agents Chemother 7: 55, 1975.
  • . Burnett GW, Sharp HW, Schuster GS. Oral microbiology and infectious disease, 4th ed. Baltimore: Williams & Wilkins, 1976.
  • . Bystedt H, Dahlbäck A, Dornbusch K, Nord CE. Concentrations of azidocillin, erythromycin, doxycycline and clindamycin in human mandibular bone. Int J Oral Surg 7: 442, 1978.
  • . Caruso LJ. The effects of doxycycline and tetracycline on fecal flora. In: Proc 7th Int Congress Chemother, Prague 1971. München, Berlin and Wien: Urban & Schwarzenberg, 1393, 1972.
  • . Donta ST. The risk of diarrhoea and colitis with antibiotic therapy. Geriatrics 32: 103, 1977.
  • . Dornbusch K, Nord CE, Wadström T. Biochemical characterization and in vitro determination of antibiotic susceptibility of clinical isolates of Bacteroides fragilis. Scand J Infect Dis 6: 253, 1974.
  • . Drasar BS, Hill MJ. Human intestinal flora. London: Academic Press, 1974.
  • . Ericsson HM, Sherris J. Antibiotic sensitivity testing. Report of an international collaborative study. Acta Pathol Microbiol Scand, Suppl. 217, 1971.
  • . Fabre J, Pitton JS, Kunz JP. Distribution and excretion of doxycycline in man. Chemotherapia 11: 73, 1966.
  • . Gordon JM, Walker CB, Goodson JM, Socransky SS. Sensitive assay for measuring tetracycline levels in gingival crevice fluid. Antimicrob Agents Chemother 17: 193, 1980.
  • . Heimdahl A, Nord CE. Effect of phenoxymethylpenicillin and clindamycin on the oral, throat and faecal microflora of man. Scand J Infect Dis 11: 233, 1979.
  • . Heimdahl A, Nord CE, Okuda K. Effect of tinidazole on the oral, throat and colon microflora of man. Med Microbiol Immunol (Berl) 168: 1, 1980.
  • . Heimdahl A, von Konow L, Nord CE. Betalactamase-producing Bacteroides species in the oral cavity in relation to penicillin therapy. J Antimicrob Chemother 8: 225, 1981.
  • . Heimdahl A, Nord CE. Effect of erythromycin and clindamycin on the indigenous human anaerobic flora and new colonization of the gastrointestinal tract. Eur J Clin Microbiol 1: 39, 1982.
  • . Holdeman LV, Cato EC, Moore WEC. Anaerobe laboratory manual. Blacksburg: Virginia Polytechnic Institute, 1977.
  • . Jailing B, Malmborg AS, Lindman A, Boréus LO. Evaluation of a micromethod for determination of antibiotic concentrations in plasma. Eur J Clin Pharmacol 4: 150, 1972.
  • . Jonsson M. Antibiotic resistance and R factors in gram-negative bacteria isolated in a hospital for infectious diseases. Scand J Infect Dis 5: 41, 1973.
  • . Jonsson M, Tunevall G. Selective pressure of tetracyclines on the faecal flora. Scand J Infect Dis, Suppl. 9: 89, 1976.
  • . Kurrle E, Bhadari S, Krieger D, Gans W, Heimpel H, Pfleiger H, Arnold R, Vanek E. Risk factors for infections of the oropharynx and the respiratory tract in patients with acute leukemia. J Infect Dis 144: 128, 1981.
  • . Malamy MH, Tally FP. Mechanism of drug-resistance transfer in Bacteroides fragilis. J Antimicrob Chemother 8, Suppl. D: 59, 1981.
  • . Mays TD, Smith CJ, Welch RA, Delfini C, Macrina LM. Novel antibiotic resistance transfer in Bacteroides. Antimicrob Agents Chemother 21: 110, 1982.
  • . Möllby R, Nord CE, Aronsson B. Diagnosis of Clostridium difficile-associated enterocolitis in Sweden. Laboratory and epidemiological aspects. Scand J Infect Dis, Suppl. 22: 30, 1980.
  • . Schach von Witteman M, Twomey TM. The disposition of doxycycline by man and dog. Chemotherapy. 16: 217, 1971.
  • . Schach von Witteman M. Pharmacokinetics of doxycycline. Opuscula Med, Suppl. 33: 5, 1974.

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