References
- Menninger H, Herborn G, Sander 0, Blechschmidt J, Rau R. A 36 month comparative trial of methotrexate and gold sodium thio-malate in the treatment of early active and erosive rheumatoid ar-thritis. Br J Ftheumatol 1998;37: 1060–8.
- Dougados M, Combe B, Cantagrel A, Goupille P, Olive P, Schattenkirchner M, et al. Combination therapy in early rheuma-toid arthritis: a randomized, controlled, double blind 52 week clini-cal trial of sulphasalazine and methotrexate compared with the single components. Ann Rheum Dis 1999;58:220–5.
- Bathon JM, Martin RW, Fleischmann RM, Tesser JR, Schiff MH, Keystone EC, et al. Comparison of etanercept and methotrexate in patients with early rheumatoid arthritis. N Engl J Med 2000;343:1586–93.
- Emery P, Breedveld FC, Lemmel EM, Kaltwasser JP, Dawes PT, Gomor B, et al. A comparison of the efficacy and safety of lefluno-mide and methotrexate for the treatment of rheumatoid arthritis. Ftheumatology 2000;159:2542–50.
- Rau R, Herborn G, Karger T, Werdier D. Retardation of radio-graphic progression and clinical results with disease modifying antirheumatic drugs. Arthritis Rheum 1991;34:1236–44.
- Choi HK, Hernan MA, Seeger JD, Robins JM, Wolfe F. Metho-trexate and mortality in patients with rheumatoid arthritis: a pro-spective study. Lancet 2002;359:1173–7.
- Shiozawa K, Tanaka Y, Yoshihara R, Imura S, Murata M, Yamane T, et al. Serum levels and pharmacodynamics of methotrexate and its metabolite 7-hydroxy methotrexate in Japanese patients with rheumatoid arthritis treated with 2-mg capsule of methotrexate three times per week. Mod Ftheumatol 2006;15:405–9.
- Hiraga Y, Yuhki Y, Itoh K, Tadano K, Takahashi Y, Mukai M. Pharmacokinetics and efficacy of low-dose methotrexate in pa-tients with rheumatoid arthritis. Mod Ftheumatol 2004;14:135–42.
- Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Cooper NS, Healey LA, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Ar-thritis Rheum 1988;31:315–24.
- Kremer JM, Petrillo GF, Hamilton RA. Pharmacokinetics and re-nal function in patients with rheumatoid arthritis receiving a stan-dard dose of oral weekly methotrexate: association with significant decreases in creatinine clearance and renal clearance of the drug after 6 months of therapy. J Ftheumatol 1995;22: 38–40.
- Marshall PS, Gertner E. Oral administration of an easily prepared solution of injectable methotrexate diluted in water: a comparison of serum concentrations vs methotrexate tablets and clinical utility. J Rheumatol 1996;23:455–8.
- Robert A, Hamilton RA, Kremer JM. The effects of food on methotrexate absorption. J Rheumatol 1995;22:630–2.
- Oguey D, Kolliker F, Gerber NJ, Reichen J. Effect of food on the bioavailability of low-dose methotrexate in patients with rheuma-toid arthritis. Arthritis Rheum 1992;35:611–4.
- Lafforgue P, Mouterde SM, Durand A, Catalin J, Acquaviva PC. Is there an interaction between low doses of corticosteroids and methotrexate in patients with rheumatoid arthritis? A pharmaco-kinetic study in 33 patients. J Rheumatol 1993;20: 263–7.
- Combe B, Edno L, Lafforgue P, Bologna C, Bernard JC, Acqua-viva PC, et al. Total and free methotrexate pharmacokinetics, with and without piroxicam, in rheumatoid arthritis patients. Br J Rheu-matol 1995;34:421–8.
- Anaya JM, Fabre D, Bressolle F, Bologna C, Alric R, Cocciglio M, et al. Effect of etodolac on methotrexate pharmacokinetics in patients with rheumatoid arthritis. J Rheumatol 1994;21:203–8.