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Review Article

Hughes syndrome (the antiphospholipid syndrome): 25 years old

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Pages 119-124 | Received 18 Oct 2007, Accepted 11 Dec 2007, Published online: 02 Jan 2014

References

  • Hughes GR. Thrombosis, abortion, cerebral disease, and the lupus anticoagulant. Br Med J (Clin Res Ed). 1983;287(6399): 1088–9.
  • Harris EN, Gharavi AE, Patel SP, Hughes GR. Evaluation of the anti-cardiofipin antibody test: report of an international workshop held 4 April 1986. Clin Exp Immunol. 1987;68(1):215–22.
  • Bertolaccini ML, Gomez S, Pareja JF, Theodoridou A, Sanna G, Hughes GR, et al. Antiphospholipid antibody tests: spreading the net. Ann Rheum Dis. 2005;64(11):1639–43.
  • Mackworth-Young CG. Antiphospholipid syndrome: multiple mechanisms. Clin Exp Immunol. 2004;136(3):393–401.
  • Wilson WA, Cucurull E. Ethnic and geographic variation in an-tiphospholipid syndrome. In: Khamashta M (editor) Hughes syndrome: antiphospholipid syndrome. 2nd ed. Springer; 2006.
  • Edwards CJ, Lian TY, Badsha H, Teh CL, Arden N, Chng HH. Hospitalization of individuals with systemic lupus erythematosus: characteristics and predictors of outcome. Lupus. 2003;12(9): 672–6.
  • Wilson WA, Gharavi AE, Koike T, Lockshin MD, Branch DW, Piette JC, et al. International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: report of an international workshop. Arthritis Rheum. 1999;42(7):1309–11.
  • Miyakis S, Lockshin MD, Atsumi T, Branch DW, Brey RL, Cervera R, et al. International consensus statement on an update of the classification criteria for definite antiphospholipid syn-drome (APS). J Thromb Haemost. 2006;4(2):295–306.
  • Montalban J, Rio J, Khamastha M, Davalos A, Codina M, Swana GT, et al. Value of immunologic testing in stroke patients. A prospective multicenter study. Stroke. 1994;25(12):2412–5.
  • Nencini P, Baruffi MC, Abbate R, Massai G, Amaducci L, Inz-itari D. Lupus anticoagulant and anticardiolipin antibodies in young adults with cerebral ischemia. Stroke. 1992;23(2):189–93.
  • Levine SR, Brey RL, Tilley BC, Thompson JL, Sacco RL, Sciacca RR, et al. Antiphospholipid antibodies and subsequent thrombo-occlusive events in patients with ischemic stroke. JAMA. 2004;291(5):576–84.
  • Hughes GR. Migraine, memory loss, and "multiple sclerosis". Neurological features of the antiphospholipid (Hughes's) syn-drome. Postgrad Med J. 2003;79(928):81–3.
  • Mackworth-Young CG, Hughes GR. Epilepsy: an early symptom of systemic lupus erythematosus. J Neurol Neurosurg Psychiatry. 1985;48(2):185.
  • Cimaz R, Meroni PL, Shoenfeld Y. Epilepsy as part of systemic lupus erythematosus and systemic antiphospholipid syndrome (Hughes syndrome). Lupus. 2006;15(4):191–7.
  • Lampropoulos CE, Koutroumanidis M, Reynolds PP, Manidakis I, Hughes GR, D'Cruz DP. Electroencephalography in the assessment of neuropsychiatric manifestations in antiphospholi-pid syndrome and systemic lupus erythematosus. Arthritis Rheum. 2005;52(3):841–6.
  • Asherson RA, Cervera R, Piette JC, Font J, Lie JT, Burcoglu A, et al. Catastrophic antiphospholipid syndrome. Clinical and lab-oratory features of 50 patients. Medicine (Baltimore). 1998;77(3): 195–207.
  • Font J, Cervera R. Cardiac manifestations of the antiphospholipid syndrome. In: Khamashta M (editors) Hughes syndrome: anti-phospholipid syndrome. 1st ed. London: Springer; 2000.
  • Williams EL, Endean AL, Edwards CJ. Myocardial infarction in a young man with antiphospholipid syndrome and cocaine use. Lupus. 2007;16(6):444–6.
  • Nair S, Khamashta MA, Hughes GR. Syndrome X and Hughes syndrome. Lupus. 2002;11(5):332.
  • Christodoulou C, Zain M, Bertolaccini ML, Sangle S, Khamashta MA, Hughes GR, et al. Prevalence of an abnormal ankle-brachial index in patients with antiphospholipid syndrome with pregnancy loss but without thrombosis: a controlled study. Ann Rheum Dis. 2006;65(5):683–4.
  • Doria A, Shoenfeld Y, Wu R, Gambari PF, Puato M, Ghirardello A, et al. Risk factors for subclinical atherosclerosis in a pro-spective cohort of patients with systemic lupus erythematosus. Ann Rheum Dis. 2003;62(11):1071–7.
  • Sangle S, D'Cruz D, Khamashta M, Tungekar MF, Abbs I, Hughes G. Goldblatt's kidney, Hughes syndrome and hyperten-sion. Lupus. 2002;11(11):699–703.
  • Asherson RA, Hughes GR. Addison's disease and primary anti-phospholipid syndrome. Lancet. 1989;2(8667):874.
  • Sangle S, Jan W, Lau I, Bennett A, Rankin SC, Hughes GR. Coeliac artery stenosis in patients with antiphospholipid syndrome/anti-phospholipid antibodies. Arthritis Rheum. 2005;52:5569.
  • Mangia A, Margaglione M, Cascavilla I, Gentile R, Cappucci G, Facciorusso D, et al. Anticardiolipin antibodies in patients with liver disease. Am J Gastroenterol. 1999;94(10):2983–7.
  • Toubi E. The ear and antiphospholipid syndrome. In: Khamashta M (editors) Hughes syndrome: antiphospholipid syndrome. 1st ed. London: Springer; 2000.
  • Asherson RA, Mackworth-Young CG, Boey ML, Hull RG, Saunders A, Gharavi AE, et al. Pulmonary hypertension in sys-temic lupus erythematosus. Br Med J (Clin Res Ed). 1983; 287(6398):1024–5.
  • Bizzaro N, Brandafise M. EDTA-dependent pseudothrombocy-topenia. Association with antiplatelet and antiphospholipid antibodies. Am J Clin Pathol. 1995;103(1):103–7.
  • Macchi L, Rispal P, Clofent-Sanchez G, Pellegrin JL, Nurden P, Leng B, et al. Anti-platelet antibodies in patients with systemic lupus erythematosus and the antiphospholipid syndrome: their relationship with the observed thrombocytopneia. Br J Haematol. 1997;98(2):336–41.
  • Montecucco C, Caporali R. Haemocytopaenias in antiphosphol-ipid syndrome. In: Khamashta M (editor). Hughes syndrome: antiphospholipid syndrome. 2nd ed. London: Springer; 2007.
  • Moore J, Ma DD, Concannon A. Non-malignant bone marrow necrosis: a report of two cases. Pathology. 1998;30(3):318–20.
  • Vasoo S, Sangle S, Zain M, D'Cruz D, Hughes G. Orthopaedic manifestations of the antiphospholipid (Hughes) syndrome. Lupus. 2005;14(5):339–45.
  • Sangle S, D'Cruz DP, Khamashta MA, Hughes GR. Antiphosp-holipid antibodies, systemic lupus erythematosus, and non-traumatic metatarsal fractures. Ann Rheum Dis. 2004;63(10): 1241–3.
  • Williams FM, Chinn S, Hughes GR, Leach RM. Critical illness in systemic lupus erythematosus and the antiphospholipid syndrome. Ann Rheum Dis. 2002;61(5):414–21.
  • Asherson RA, Cervera R, de Groot PG, Erkan D, Boffa MC, Piette JC, et al. Catastrophic antiphospholipid syndrome: international consensus statement on classification criteria and treatment guidelines. Lupus. 2003;12(7):530–4.
  • Derksen RH, Khamashta MA, Branch DW. Management of the obstetric antiphospholipid syndrome. Arthritis Rheum. 2004;50(4): 1028–39.
  • Letelfier E, Hughes GR. "Listen to the patient"—anticoagulation is critical in the antiphospholipid (Hughes's) syndrome. J Rheu-matol. 2003;30(4):897.
  • Veneri D, Ambrosetti A, Franchini M, Mosna F, Poli G, Pizzolo G. Remission of severe antiphospholipid syndrome associated with non-Hodgkin's B-cell lymphoma after combined treatment with rituximab and chemotherapy. Haematologica. 2005;90(Suppl): ECR37.
  • Rubenstein E, Arkfeld DG, Metyas S, Shinada S, Ehresmann S, Liebman HA. Rituximab treatment for resistant antiphospholipid syndrome. J Rheumatol. 2006;33(2):355–7.
  • Sherer Y, Shoenfeld Y. Intravenous immunoglobulin for immu-nomodulation of systemic lupus erythematosus. Autoimmun Rev. 2006;5(2):153–5.

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