References
- Eigler A, Sinha B, Hartmann G, Endres S. Taming TNF: strate-gies to restrain this proinflammatory cytokine. Immunol Today. 1997;18:487–92.
- Keffer J, Probert L, Cazlaris H, Georgopoulos S, Kaslaris E, Kioussis D, et al. Transgenic mise expressing human tumor necrosis factor: predictive genetic model of arthritis. EMBO J. 1991;10:4025–31.
- Khanna D, Wu H, Park G, Gersuk V, Gold RH, Nepom GT, et al. Association of tumor necrosis factor a polymorphism, but not the shared epitope, with increased radiographic progression in a seropositive rheumatoid arthritis inception cohort. Arthritis Rheum. 2006;54:1105–16.
- Higuchi T, Seki N, Kamizono S, Yamada A, Kimura A, Kato H, et al. Polymorphism of the 5'-flanking region of the human tumor necrosis factor (TNF)- a gene in Japanese. Tissue Antigens. 1998;51:605–12.
- Seki N, Kamizono S, Yamada A, Higuchi T, Matsumoto H, Niiya F, et al. Polymorphisms in the 5'-flanking region of the tumor necrosis factor (TNF)- a gene in patients with rheumatoid arthritis. Tissue Antigens. 1999;54:194–7.
- Shibue T, Tsuchiya N, Komata T, Matsushita M, Shiota M, Ohashi J, et al. Tumor necrosis factor a 5'-flanking region, tumor necrosis factor receptor II, and HLA-DRB1 polymorphisms in Japanese patients with rheumatoid arthritis. Arthritis Rheum. 2000;43:753–7.
- Higami K, Hakoda M, Matsuda Y, Ueda H, Kashiwazaki S. Lack of association of HLA-DRB1 genotype with radiologic progres-sion in Japanese patients with early rheumatoid arthritis. Arthritis Rheum. 1997;40: 2241–7.
- Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 1988;31:315–24.
- Furuya T, Hakoda M, Ichikawa N, Higami K, Nanke Y, Yago T, et al. Associations between HLA-DRB1, RANK, RANKL, OPG, and IL-17 genotypes and disease severity phenotypes in Japanese patients with early rheumatoid arthritis. Clin Rheumatol. 2007;26:2137–41.
- Matsushita M, Tsuchiya N, Nakayama T, Ohashi J, Shibue T, Shiota M, et al. Allele typing of human TNFA 5'-flanking region using polymerase chain reaction-preferential homoduplex for-mation assay (PCR-PHFA): linkage disequilibrium with HLA class I and II gene in Japanese. Tissue Antigens. 1999;54:478–84.
- Kitamura Y, Moriguchi M, Kaneko H, Morisaki H, Morisaki T, Toyama K, et al. Determination of probability distribution of diplotype configuration (diplotype distribution) for each subject from genotype data using the EM algorithm. Ann Hum Genet. 2002;66:183–93.
- Udalova IA, Richardson A, Denys A, Smith C, Ackerman H, Foxwell B, et al. Functional consequences of a polymorphism affecting NF-KB p50-p50 binding to the TNF promoter region. Mol Cell Biol. 2000;20:9113–9.
- Udalova IA, Richardson A, Ackerman H, Wordsworth P, Kwiatkowski D. Association of accelerated erosive rheumatoid arthritis with a polymorphism that alters NF-KB binding to the TNF promoter region. Rheumatology. 2002;41:830–1.
- Van Heel DA, Udalova IA, De Silva AP, McGovern DP, Kinouchi Y, Hull J, et al. Inflammatory bowel disease is asso-ciated with a TNF polymorphism that affects an interaction between the OCT! and NFKB transcription factors. Hum Mol Genet. 2002;11:1281–9.
- Van Krugten MV, Kaijzel EL, Bakker AM, Drossaers-Bakker KW, Huizinga TWJ, Hazes JMW, et al. Definition of a TNF haplotype that is associated with protection from erosive disease in RA. Arthritis Rheum. 1999;42:5282.
- Kang CP, Lee KW, Yoo DH, Kang C, Bae SC. The influence of a polymorphism at position -857 of the tumor necrosis factor a gene on clinical response to etanercept therapy in rheumatoid arthritis. Rheumatology. 2005;44: 547–52.
- Skoog T, van't Hooft FM, Kallin B, Jovinge S, Boquist S, Nilsson J, et al. A common functional polymorphism(C-A substitution at position -863) in the promoter region of the tumor necrosis factor-a (TNF-) gene associated with reduced circulating levels of TNF-a. Hum Mol Genet. 1999;8: 1443–9.
- Kaltenhauser S, Wagner U, Schuster E, Wassmuth R, Arnold S, Seidel W, et al. Immunogenetic markers and seropositivity pre-dict radiological progression in early rheumatoid arthritis independent of disease activity. J Rheumatol. 2001;28:735–44.
- Mattey DL, Hassell AB, Dawes PT, Cheung NT, Poilton KV, Thomson W, et al. Independent association of rheumatoid factor and the HLA-DRB1 shared epitope with radiographic outcome in rheumatoid arthritis. Arthritis Rheum. 2001;44:1529–33.
- Valenzuela-Castano A, Garcia-Lopez A, Perez-Vilches D, Rodriguez-Perez R, Gonzalez-Escribano MF, Nunez-Roldan A. The predictive value of the HLA shared epitope for severity of radiological joint damage in patients with rheumatoid arthritis. A 10 year observational prospective study. J Rheumatol. 2000;27:571–4.