Role of the β1 integrin molecule in T-cell activation and migration

References

• Hynes RO. Integrins: versatility, modulation, and signaling in cell adhesion. Cell 1992;69:11–25.
   PubMed Web of Science ®Google Scholar
• Schwartz MA, Lechene C, Ingber DE. Insoluble fibronectin acti-vates the Na/H antiporter by clustering and immobilizing integrin alpha 5 beta 1, independent of cell shape. Proc Natl Acad Sci USA 1991;88: 7849–53.
   Google Scholar
• Shattil SJ, Brugge JS. Protein tyrosine phosphorylation and the adhesive functions of platelets. Curr Opin Cell Biol 1991;3:869–79.
   PubMed Web of Science ®Google Scholar
• Sultan C, Plantavid M, Bachelot C, Grondin P, Breton M, Mauco G, et al. Involvement of platelet glycoprotein(alpha IIb-beta 3 integrin) in thrombin-induced synthesis of phosphatidy-linositol 3',4'-bisphosphate. J Biol Chem 1991;266:23554–7.
   PubMed Web of Science ®Google Scholar
• Matsuyama T, Yamada A, Kay J, Yamada KM, Akiyama SK, Schlossman SF, et al. Activation of CD4 cells by fibronectin and anti-CD3 antibody. A synergistic effect mediated by the VLA-5 fibronectin receptor complex. J Exp Med 1989;170:1133–48.
   Google Scholar
• Masuyama J, Berman JS, Cruikshank WW, Morimoto C, Center DM. Evidence for recent as well as long-term activation of T-cells migrating through endothelial cell monolayers in vitro. J Immunol 1992;148:1367–74.
   Google Scholar
• Nojima Y, Humphries MJ, Mould AP, Komoriya A, Yamada KM, Schlossman SF, et al. VLA-4 mediates CD3-dependent CD4+ T-cell activation via the CS1 alternatively spliced domain of fibronectin. J Exp Med 1990;172:1185–92.
   PubMed Web of Science ®Google Scholar
• Yamada A, Nojima Y, Sugita K, Dang NH, Schlossman SF, Morimoto C. Cross-linking of VLA/CD29 molecule has a co-mitogenic effect with anti-CD3 on CD4 cell activation in a serum-free culture system. Eur J Immunol 1991;21:319–25.
   PubMed Web of Science ®Google Scholar
• Yamada A, Nikaido T, Nojima Y, Schlossman SF, Morimoto C. Activation of human CD4 T-Iymophocytes. Interaction of fibronectin with VLA-5 receptor on CD4 cells induces the AP-1 transcription factor. J Immunol 1991;146: 53–6.
   Google Scholar
• Salomon DR, Mojcik CF, Chang AC, Wadsworth S, Adams DH, Coligan JE, et al. Constitutive activation of integrin alpha 4 beta 1 defines a unique stage of human thymocyte development. J Exp Med 1994;179:1573–84.
   PubMed Web of Science ®Google Scholar
• Williams DA, Rios M, Stephens C, Patel VP. Fibronectin and VLA-4 in haematopoietic stem cell-microenvironment interac-tions. Nature (London) 1991;352:438–41.
   PubMed Web of Science ®Google Scholar
• Morimoto C, Romain PL, Fox DA, Anderson P, DiMaggio M, Levine H, et al. Abnormalities in CD4+ T-Iymophocyte subsets in inflammatory rheumatic disease. Am J Med 1988;84:817–25.
   PubMed Web of Science ®Google Scholar
• Pitzalis C, Kingsley G, Murphy J, Panayi G. Abnormal distribution of helper-inducer and suppressor-inducer T-lymophocyte subsets in the rheumatoid joint. Chin Immunol Immunopathol 1987;45: 252–8.
   PubMedGoogle Scholar
• Sobel RA, Haller DA, Castro EE, Morimoto C, Weiner HL. Suppressor-inducer T-cells are selectively decreased in multiple sclerosis lesions. J Immunol 1988;140:2210–14.
   Google Scholar
• Hemler ME, Glass D, Coblyn JS, Jacobson JG. Very late activa-tion antigens on rheumatoid synovial fluid lymphocytes. Associa-tion with stages of T-cell activation. J Chin Invest 1986;78:696–702.
   Google Scholar
• Laffon A, Garcia-Vicuna R, Humbra A, Postigo AA, Corbi AL, deLandazuri MO, et al. Upregulated expression and function of VLA-4 fibronectin receptors on human activated T-cells in rheu-matoid arthritis. J Clin Invest 1991;88: 546–52.
   Google Scholar
• Takeuchi T, Amano K, Sekine H, Koide J, Abe T. Upregulated expression and function of integrin adhesive receptors in systemic lupus erythmatosno patents with vasailites. J Clin Invest 1993;92:3008–16.
   Google Scholar
• Mojcik CF, Shevach EM. Adhesion molecules: a rheumatologic perspective. Arthritis Ftheumatal 1997;40:991–1004.
   PubMed Web of Science ®Google Scholar
• Nojima Y, Rothstein DM, Sugita K, Schlossman SF, Morimoto C. Ligation of VLA-4 on T-cells stimulates tyrosine phosphorylation of a 105-kD protein. J Exp Med 1992;175: 1045–53.
   Google Scholar
• Sato T, Tachibana K, Nojima Y, D'Avirro N, Morimoto C. Role of the VLA-4 molecule in T-cell co-stimulation. Identification of the tyrosine phosphorylation pattern induced by the ligation of VLA-4. J Immunol 1995;155: 2938–47.
   Google Scholar
• Nojima Y, Tachibana T, Sato T, Schlossman SF, Morimoto C. Focal adhesion kinase (pp125FAK) is tyrosine phosphorylated after engagement of ct4(31 and ct5(31 integrins on human T-lymphoblastic cells. Cell Immunol 1995;161: 8–13.
   Google Scholar
• Minegishi M, Tachibana K, Sato T, Iwata S, Nojima Y, Morimoto C. Structure and function of Cas-L, a 105-kD Crk-associated sub-strate-related protein that is involved in beta 1 integrin-mediated signaling in lymphocytes. J Exp Med 1996;184:1365–75.
   PubMed Web of Science ®Google Scholar
• Tachibana K, Sato T, D'Avirro N, Morimoto C. Direct association of pp125FAK with paxillin, the focal adhesion-targeting mecha-nism of pp125FAK. J Exp Med 1995;182: 1089–99.
   Google Scholar
• Polte TR, Hanks SK. Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas. Proc Natl Acad Sci USA 1995;92:10678–82.
   PubMed Web of Science ®Google Scholar
• Songyang Z, Shoelson SE, Chaudhuri M, Gish G, Pawson T, Haser WG, et al. 5H2 domains recognize specific phosphopeptide sequences. Cell 1993;72:767–78.
   PubMed Web of Science ®Google Scholar
• Ishino M, Ohba T, Sasaki H, Sasaki T. Molecular cloning of a cDNA encoding a phosphoprotein, Efs, which contains a Src homology 3 domain and associates with Fyn. Oncogene 1995;11: 2331–8.
   PubMed Web of Science ®Google Scholar
• Sakai R, Iwamatsu A, Hirano N, Ogawa S, Tanaka T, Mano H, et al. A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner. EMB O (Eur Mol Biol Organ) J 1994;13:3748–56.
   PubMed Web of Science ®Google Scholar
• Tachibana K, Urano T, Fujita H, Ohashi Y, Kamiguchi K, Iwata S, et al. Tyrosine phosphorylation of Crk-associated substrates by focal adhesion kinase: a putative mechanism for the integrin-mediated tyrosine phosphorylation of Crk-associated substrates. J Biol Chem 1997;272:29083–90.
   PubMed Web of Science ®Google Scholar
• Ohashi Y, Tachibana K, Kamiguchi K, Fujita H, Morimoto C. T-een receptor-mediated tyrosine phosphorylation of Cas-L, a 105kDa Crk-associated substrate-related protein, and its associa-tion of Crk and C3G. J Biol Chem 1998;273: 6446–51.
   Google Scholar
• Tanaka S, Morishita T, Hashimoto Y, Hattori S, Nakamura S, Shibuya M, et al. C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CFtK and GRB2/ASH proteins. Proc Natl Acad Sci USA 1994;91:3443–7.
   PubMed Web of Science ®Google Scholar
• Gotoh T, Hattori S, Nakamura S, Kitayama H, Noda M, Takai Y, et al. Identification of Rapl as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G. Mol Cell Biol 1995;15:6746–53.
   PubMed Web of Science ®Google Scholar
• Udagwa T, Woodside DG, McIntyre BW. ct4(31 (CD49d/CD29) integrin co-stimulation of human T-cells enhances transcription factor and cytokine induction in the absence of altered sensitivity to anti-CD3 stimulation. J Immunol 1996;157: 1965–72.
   Google Scholar
• Ennis E, Isberg RR, Shimizu Y. Very late antigen 4-dependent adhesion and co-stimulation of resting human T-cells by the bacterial beta 1 integrin ligand invasin. J Exp Med 1993;177: 207–212.
   Google Scholar
• Kamiguchi K, Tachibana K, Iwata S, Ohashi Y, Morimoto C. Cas- L is required for (31 integrin-mediated co-stimulation in human T-eens. J Immunol 1999;163: 563–8.
   Google Scholar
• Law SF, Estojak J, Wang B, Mysliwiec T, Kruh G, Golemis EA. Human enhancer of filamentation 1, a novel p130cas-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiae. Mol Cell Biol 1996;16:3327–37.
   PubMed Web of Science ®Google Scholar
• Ohashi Y, Iwata S, Kamiguchi K, Morimoto C. Tyrosine phospho-rylation of Cas-L is a critical element for T-cell receptor- and 31 integrin-induced T-Iymophocyte migration. J Immunol 1999;163: 3727–34.
   PubMed Web of Science ®Google Scholar
• Weiss A, Littman DR. Signal transduction by lymphocyte antigen receptors. Cell 1994;76:263–74.
   PubMed Web of Science ®Google Scholar
• Wange RL, Samelson LE. Complex complexes: signaling at the TCR. Immunity 1996;5:197–205.
   PubMed Web of Science ®Google Scholar
• Ftibon V, Satiel AR. Nerve growth factor stimulates the tyrosine phosphorylation of endogenous Crk-II and augments its associa-tion with p130Cas in PC-12 cells. J Biol Chem 1996;13:7375–80.
   Google Scholar
• Schraw W, Richmond A. Melanoma growth stimulatory activity signaling through the class II interleukin-8 receptor enhances the tyrosine phosphorylation of Crk-associated substrate, p130, and a 70-kilodalton protein. Biochem 1995;34:13760–7.
   PubMed Web of Science ®Google Scholar
• Ingham RJ, Krebs DL, Barbazuk SM, Turck CW, Hirai H, Matsuda M, et al. B-cell antigen receptor signaling induces the formation of complexes containing the Crk adapter proteins. J Biol Chem 1996;50:32306–14.
   Web of Science ®Google Scholar
• Manie SN, Beck AR, Astier A, Law SF, Canty T, Hirai H, et al. The related adhesion focal tyrosine kinase differentially phospho-rylates p130Cas and the Cas-like protein, p105HEF1. J Biol Chem 1997;272:4230–6.
   PubMed Web of Science ®Google Scholar
• Schlaepfer DD, Broome MA, Hunter T. Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins. Mol Cell Biol 1997;17: 1702–713.
   Google Scholar
• Alexandropoulos K, Baltimore D. Coordinate activation of c-Src by 5H3- and 5H2-binding sites on a novel p130Cas-related protein, Sin. Genes Dev 1996;10:1341–55.
   PubMed Web of Science ®Google Scholar
• Hasegawa H, Kiyokawa E, Tanaka S, Nagashima K, Gotoh N, Shibuya M, et al. DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane. Mol Cell Biol 1996;16:1770–6.
   PubMed Web of Science ®Google Scholar
• Feller SM, Knudsen B, Hanafusa H. Cellular proteins binding to the first Src homology 3 (5H3) domain of the proto-oncogene product c-Crk indicate Crk-specific signaling pathways. Oncogene 1995;10: 1465–73.
   Google Scholar
• Ren R, Ye ZS, Baltimore D. Abl protein-tyrosine kinase selects the Crk adapter as a substrate using 5H3-binding sites. Genes Dev 1994;8: 783–95.
   Google Scholar
• Kitayama H, Sugimoto Y, Matsuzaki T, Ikawa Y, Noda M. A ras-related gene with transformation suppressor activity. Cell 1989;56:77–84.
   Google Scholar
• Hu CD, Kariya K, Shirouzu M, Yokoyama S, Kataoka T. Coassociation of RaplA and Ha-Ras with Raf-1 N-terminal region interferes with ras-dependent activation of Raf-1. J Biol Chem 1997;272: 11702–705.
   Google Scholar
• Tanaka S, Ouchi T, Hanafusa H. Downstream of Crk adaptor signaling pathway: activation of Jun kinase by v-Crk through the guanine nucleotide exchange protein C3G. Proc Natl Acad Sci USA 1997;94: 2356–61.
   Google Scholar
• Su B, Jacinto E, Hibi M, Kallunki T, Karin M, Ben-Neriah Y. JNK is involved in signal integration during co-stimulation of T-lymophocytes. Cell 1994;77:727–36.
   Google Scholar
• Bennett AM, Hausdorff SF, O'Reilly AM, Freeman RM, Neel BG. Multiple requirements for SHPTP2 in epidermal growth factor-mediated cell cycle progression. Mol Cell Biol 1996;16: 1189–202.
   Google Scholar
• Owaki H, Varma R, Gillis B, Bruder JT, Rapp UR, Davis LS, et al. Raf-1 is required for T cell IL2 production. EMBO J 1993;12:4367–73.
   PubMed Web of Science ®Google Scholar