REFERENCES
- PhoenixCH.GoyRW.GerallAA.YoungWC.Organizing action of prenatally administered testosterone propionate on the tissues mediating mating behavior in the female guinea pig.Endocrinology.19596536938214432658
- Pfaff DW. Morphological changes in the brains of adult male rats after neonatal castration.J Endocrinol.1966364154165926956
- NottebohmF.ArnoldAP.Sexual dimorphism in vocal control areas of the songbird brain.Science.1976194211213959852
- RaismanG.FieldPM.Sexual dimorphism in the preoptic area of the rat.Science.19711737317335568506
- RaismanG.FieldPM.Sexual dimorphism in the neuropil of the preoptic area of the rat and its dependence on neonatal androgen.Brain Res.1973541294122682
- GorskiRA.GordonJH.ShryneJE.SouthamAM.Evidence for a morphological sex difference within the medial preoptic area of the rat brain.Brain Res.1978148333346656937
- RainbowTC.ParsonsB.McEwenBS.Sex differences in rat brain oestrogen and progestin receptors.Nature.19823006486497144917
- KendallDA.StancelGM.EnnaSJ.Imipramine: effect of ovarian steroids on modifications in serotonin receptor binding.Science.1981211118311856258229
- LuineVN.McEwenBS.Sex differences in cholinergic enzymes of diagonal band nuclei in the rat preoptic area.Neuroendocrinology.1983364754826877524
- ZhangL.LiPP.FengX.et al.Sex-related differences in neuronal cell survival and signaling in rats.Neurosci Lett.2003337656812527389
- ZhangL.LiB.hao W, et al. Sex-related differences in MAPKs activation in rat astrocytes: effects of estrogen on cell death.Moi Brain Res.200210311112106687
- GrossmanMl.KirsnerJB.GillespieIE.Basal and histalog-stimulated gastric secretion in control subjects and in patients with peptic ulcer or gastric cancer.Gastroenterology.196345142614046306
- TahirH.SumiiK.HarumaK.et al.A statistical evaluation on the age and sex distribution of basal serum gastrin and gastric acid secretion in subjects with or without peptic ulcer disease.Hiroshima J Med Sci.1984331251306480375
- KekkiM.SamloffIM.lhamakiT.VarisK.SiuralaM.Age- and sex-related behaviour of gastric acid secretion at the population level.Scand J Gastroenterol.1982177377437188552
- PoulsenJ.LovgreenNA.AmdrupE.Fasting and food-stimulated serum gastrin concentration in 151 duodenal ulcer patients and 41 non-dyspeptic volunteers. Significant sex differences.Scand J Gastroenterol.1986218818853775253
- LindahlA.UngellAL.KnutsonL.LennernesH.Characterization of fluids from the stomach and proximal jejunum in men and women.Pharm Res.1997144975029144738
- FeldmanM.RichardsonCT.WalshJH.Sex-related differences in gastrin release and parietal cell sensitivity to gastrin in healthy human beings.J Clin invest.1983717157206826731
- DressmanJB.BerardiRR.DermentzoglouLC.et al.Upper gastrointestinal (GI) pH in young, healthy men and women.Pharm Res.199077567612395805
- GraffJ.BrinchK.MadsenJL.Gastrointestinal mean transit times in young and middle-aged healthy subjects.Clin Physiol.20012125325911318834
- SadikR.AbrahamssonH.StotzerPO.Gender differences in gut transit shown with a newly developed radiological procedure.Scand J Gastroenterol.200338364212608462
- MadsenJL.Effects of gender, age, and body mass index on gastrointestinal transit times.Dig Dis Sci.199237154815531396002
- NimmoWS.Drugs, diseases and altered gastric emptying.Clin Pharmacokinet.19761189203797497
- HermanssonG.SivertssonR.Gender-related differences in gastric emptying rate of solid meals.Dig Dis Sci.199641199419988888713
- KnightLC.ParkmanHP.BrownKL.et al.Delayed gastric emptying and decreased antral contractility in normal premenopausal women compared with men.Am J Gastroenterol.1997929689759177512
- DatzFL.ChristianPE.MooreJ.Gender-related differences in gastric emptying.J Nucl Med.198728120412073598704
- BenninkR.PeetersM.Van denMaegdenbergh V.et al.Evaluation of small-bowel transit for solid and liquid test meal in healthy men and women.Eur J Nucl Med.1999261560156610638407
- BenninkR.PeetersM.Van den MaegdenberghV.et al.Comparison of total and compartmental gastric emptying and antral motility between healthy men and women.Eur J Nucl Med.199825129312999724379
- NotivolR.CarrioI.CanoL.EstorchM.VilardellF.Gastric emptying of solid and liquid meals in healthy young subjects.Scand J Gastroenterol.198419110711136533779
- HutsonWR.RoehrkasseRL.WaldA.Influence of gender and menopause on gastric emptying and motility.Gastroenterology.19899611172909416
- GrybackP.HermanssonG.LyrenasE.et al.Nationwide standardisation and evaluation of scintigraphic gastric emptying: reference values and comparisons between subgroups in a multicentre trial.Eur J Nucl Mled.200027647655
- Caballero-PlasenciaAM.Valenzuela-BarrancoM.Martin-RuizJL.HerreriasGutierrezJM.Esteban-CarreteroJM.Are there changes in gastric emptying during the menstrual cycle?Scand J Gastroenterol.19993477277610499477
- WedmannB.SchmidtG.WegenerM.et al.Effects of age and gender on fat-induced gallbladder contraction and gastric emptying of a caloric liquid meal: a sonographic study.Am J Gastroenterol.199186176517701962620
- KlotzU.Pathophysiological and disease-induced changes in drug distribution volume: pharmacokinetic implications.Clin Pharmacokinet.19761204218797498
- GleiterCH.Gundert-RemyU.Gender differences in pharmacokinetics.Eur J Drug Metab Pharmacokinet.1996211231288839685
- HashimotoS.MiwaM.AkasofuK.NishidaE.Changes in 40 serum proteins of postmenopausal women.Maturitas.19911323331861640
- BlainPG.MucklowJC.RawlinsMD.et al.Determinants of plasma alpha 1-acld glycoprotein (AAG) concentrations in health.Br J Clin Pharmacol.1985205005024074621
- KishinoS.NomuraA.ItohS.et al.Age- and gender-related differences in carbohydrate concentrations of alphal-acid glycoprotein variants and the effects of glycoforms on their drug-binding capacities.Eur J Clin Pharmacol.20025862162812483455
- FeelyJ.GrimmT.A comparison of drug protein binding and alpha 1acid glycoprotein concentration in Chinese and Caucasians.Br J Clin Pharmacol.1991315515521888624
- TuckCH.HolleranS.BerglundL.Hormonal regulation of lipoprotein(a) levels: effects of estrogen replacement therapy on lipoprotein(a) and acute phase reactant in postmenopausal women.Arterioscl Throrn Vas Biol.19971718221829
- PollockBG.Gender differences in psychotropic drug metabolism.Psychopharmacol Bull.1997332352419230636
- IsrailiZH.DaytonPG.Human alpha-1-glycoprotein and its interactions with drugs.Drug Metab Rev.20013316123511495502
- KishinoS.NomuraA.DiZS.et al.Alpha-1-acid glycoprotein concentration and the protein binding of disopyramide in healthy subjects.J Clin Pharmacol.1995355105147657852
- KeefeD.YeeY.KatesR.Verapamil protein binding in patients and in normal subjects.Clin Pharmacol Ther.19812921266970111
- Krecic-ShepardME.ParkK.BarnasC.et al.Race and sex influence clearance of nifedipine: results of a population study.Clin Pharmacol Ther.20006813014210976544
- Report to the Medical Research Council by its Clinical Psychiatry Committee. Clinical trial of the treatment of depressive illness.BMJ.1965188188614257398
- BjôrntorpP.BengtssonC.BlohméG.et al.Adipose tissue fat cell size and number in relation to metabolism in randomly selected middle-aged men and women.Metabolism.1971209279355097682
- NovakLP.Aging, total body potassium, fat-free mass, and cell mass in males and females between ages 18 and 85 years.J Gerontol.1972274384434627605
- BickelWK.OlivetoAH.KamienJB.HigginsST.HughesJR.A novel response procedure enhances the specificity and sensitivity of a triazolam discrimination in humans.J Pharmacol Exp Ther.19932643603678423538
- RasmussenBB.BrixTH.KyvikKO.BrosenK.The interindividual differences in the 3-demethylation of caffeine alias CYP1A2 is determined by both genetic and environmental factors.Pharmacogenetics.20021247347812172216
- RellingMV.LinJS.AyersGD.EvansWE.Racial and gender differences in W-acetyltransferase, xanthine oxidase, and CYP1A2 activities.Clin Pharmacol Ther.1992526436581458773
- VistisenK.PoulsenHE.LoftS.Foreign compound metabolism capacity in man measured from metabolites of dietary caffeine.Carcinogenesis.199213156115681394840
- RasmussenBB.BrosenK.Determination of urinary metabolites of caffeine for the assessment of cytochrome P4501 A2, xanthine oxidase, and Wacetyltransferase activity in humans.Ther Drug Monit.1996182542628738764
- Tantcheva-PoorI.ZaiglerM.RietbrockS.FuhrU.Estimation of cytochrome P-450 CYP1 A2 activity in 863 healthy Caucasians using a salivabased caffeine test.Pharmacogenetics.1999913114410376760
- JenningsTS.NafzigerAN.DavidsonL.BertinoJS.JrGender differences in hepatic induction and inhibition of theophylline pharmacokinetics and metabolism.J Lab Clin Med.19931222082168340707
- NafzigerAN.BertinoJS.JrSex-related differences in theophylline pharmacokinetics.Eur J Clin Pharmacol.198937971002591473
- BockKW.SchrenkD.ForsterA.et al.The influence of environmental and genetic factors on CYP2D6, CYP1 A2 and UDP-glucuronosyltransferases in man using sparteine, caffeine, and paracetamol as probes.Pharmacogenetics.199442092187987405
- Ou-YangDS.HuangSL.WangW.et al.Phenotypic polymorphism and gender-related differences of CYP1 A2 activity in a Chinese population.Br J Clin Pharmacol.20004914515110671909
- ZaiglerM.RietbrockS.SzymanskiJ.et al.Variation of CYP1 A2-dependent caffeine metabolism during menstrual cycle in healthy women.IntJ Clin Pharmacol Ther.20003823524410839467
- PantuckEJ.KuntzmanR.ConneyAH.Decreased concentration of phenacetin in plasma of cigarette smokers.Science.1972175124812505061244
- KalowW.TangBK.Use of caffeine metabolite ratios to explore CYP1A2 and xanthine oxidase activities.Clin Pharmacol Ther.1991505085191934864
- SchrenkD.BrockmeierD.MorikeK.BockKW.EichelbaumM.A distribution study of CYP1A2 phenotypes among smokers and non-smokers in a cohort of healthy Caucasian volunteers.Eur J Clin Pharmacol.1998533613679516038
- CaubetMS.LaplanteA.CailleJ.BrazierJL.[13C] Aminopyrine and [13C]caffeine breath test: influence of gender, cigarette smoking and oral contraceptives intake.Isotopes Environ Health Stud.200238717712219983
- AndersonGD.Sex differences in drug metabolism: cytochrome P-450 and uridine diphosphate glucuronosyltransferase.J Gend Specif Med.20025253311859684
- ChouWH.YanFX.Robbins-WeilertDK.et al.Comparison of two CYP2D6 genotyping methods and assessment of genotype-phenotype relationships.Clin Chern.200349542551
- SchwartzJB.The influence of sex on pharmacokinetics.Clin Pharmacokinet.20034210712112537512
- LinY.AndersonGD.KantorE.OjemannLM.WilenskyAJ.Differences in the urinary excretion of 6-beta-hydroxycortisol/cortisol between Asian and Caucasian women.J Clin Pharmacol.19993957858210354961
- KharaschED.MautzD.SennT.LentzG.CoxK.Menstrual cycle variability in midazolam pharmacokinetics.J Clin Pharmacol.19993927528010073327
- KashubaAD.NafzigerAN.KearnsGL.et al.Quantification of intraindividual variability and the influence of menstrual cycle phase on CYP2D6 activity as measured by dextromethorphan phenotyping.Pharmacogenetics.199884034109825832
- BelleDJ.CallaghanJT.GorskiJC.et al.The effects of an oral contraceptive containing ethinyloestradiol and norgestrel on CYP3A activity.Br J Clin Pharmacol.200253677411849197
- BartoliA.XiaodongS.GattiG.et al.The influence of ethnic factors and gender on CYP1A2-mediated drug disposition: a comparative study in Caucasian and Chinese subjects using phenacetin as a marker substrate.Ther Drug Monit.1996185865918885124
- CampbellEA.LintonEA.WolfeCD.et al.Plasma corticotropin-releasing hormone concentrations during pregnancy and parturition.J Clin Endocrinol Metab.198764105410593494036
- PatwardhanRV.DesmondPV.JohnsonRF.SchenkerS.Impaired elimination of caffeine by oral contraceptive steroids.J Lab Clin Med.1980956036087359014
- LabbeL.SiroisC.PiloteS.et al.Effects of gender, sex hormones, time variables and physiological urinary pH on apparent CYP2D6 activity as assessed by metabolic ratios of marker substrates.Pharmacogenetics.20001042543810898112
- HaggS.Spigset0.DahlqvistR.Influence of gender and oral contraceptives on CYP2D6 and CYP2C19 activity in healthy volunteers.Br J Clin Pharmacol.20015116917311259990
- TammingaWJ.WernerJ.OosterhuisB.et al.CYP2D6 and CYP2C19 activity in a large population of Dutch healthy volunteers: indications for oral contraceptive-related gender differences.Eur J Clin Pharmacol.19995517718410379632
- WadeliusM.DarjE.PrenneG.RaneA.Induction of CYP2D6 in pregnancy.Clin Pharmacol Ther.1997624004079357391
- LlerenaA.CobaledaJ.MartinezC.BenitezJ.Interethnic differences in drug metabolism: influence of genetic and environmental factors on debrisoquine hydroxylation phenotype.Eur J Drug Metab Pharmacokinet.1996211291388839686
- McCuneJS.LindleyC.DeckerJL.et al.Lack of gender differences and large intrasubject variability in cytochrome P450 activity measured by phenotyping with dextromethorphan.J Clin Pharmacol.20014172373111452704
- HerrlingerC.KlotzU.Drug metabolism and drug interactions in the elderly.Best Pract Res Clin Gastroenterol.20011589791811866484
- EvansDA.KrahnP.NarayananN.The mephenytoin (cytochrome P450 2C19) and dextromethorphan (cytochrome P450 2D6) polymorphisms in Saudi Arabians and Filipinos.Pharmacogenetics.1995564717663530
- BertilssonL.Geographical/interracial differences in polymorphic drug oxidation. Current state of knowledge of cytochromes P450 (CYP) 2D6 and 2C19.Clin Pharmacokinet.1995291922098521680
- TassaneeyakulW.TawaleeA.TassaneeyakulW.et al.Analysis of the CYP2C19 polymorphism in a North-eastern Thai population.Pharmacogenetics.20021222122511927837
- ScriptureC.PieperJ.Clinical pharmacokinetics of fluvastatin.Clin Pharmacokinet.20014026328111368292
- TabriziAR.ZehnbauerBA.BoreckiIB.et al.The frequency and effects of cytochrome P450 (CYP) 2C9 polymorphisms in patients receiving warfarin.J Am Coll Surg.200219426727311893129
- WessonLG.Renal hemodynamics in physiological states.Physiology of the Human Kidney. New York, NY: Grune and Stratton196996108
- JamesGD.SealeyJE.AldermanM.et al.A longitudinal study of urinary creatinine and creatinine clearance in normal subjects. Race, sex, and age differences.Am J Hypertens.198811241313401350
- SlackTK.WilsonDM.Normal renal function: CIN and CPAH in healthy donors before and after nephrectomy.Mayo Clin Proc.1976512963001263599
- FinneyH.NewmanDJ.PriceCP.Adult reference ranges for serum cystatin C, creatinine and predicted creatinine clearance.Ann Clin Biochem.200037495910672373
- MasareiJRL.Validity of corrections for creatinine excretion and creatinine clearance.NZMedJ.197582197198
- HolazoAA.WinklerMB.PatelIH.Effects of age, gender and oral contraceptives on intramuscular midazolam pharmacokinetics.J Clin Pharmacol.198828104010453243917
- BaumgartnerMG.CautreelsW.LangenbahnH.Biotransformation and pharmacokinetics of tetrazepam in man.Arzneimittelforschung Drug Res.1984347247296148954
- KristjanssonF.ThorsteinssonSB.Disposition of alprazolam in human volunteers. Differences between genders.Acta Pharm Nord.199132492501781916
- van SteveninckAL.WallnoferAE.SchoemakerRC.et al.A study of the effects of long-term use on individual sensitivity to temazepam and lorazepam in a clinical population.Br J Clin Pharmacol.1997442672759296321
- SmithRB.DivollM.GillespieWR.GreenblattDJ.Effect of subject age and gender on the pharmacokinetics of oral triazolam and temazepam.J Clin Psychopharmacol.198331721766135721
- ShaderRl.GreenblattDJ.CirauloDA.et al.Effect of age and sex on disposition of desmethyldiazepam formed from its precursor clorazepate.Psychopharmacology.1981751931976119726
- DivollM.GreenblattDJ.OchsHR.ShaderRl.Absolute bioavailability of oral and intramuscular diazepam: effects of age and sex.Anesth Analg.198362186849499
- OchsHR.OttenH.GreenblattDJ.DenglerHJ.Diazepam absorption: effects of age, sex, and Billroth gastrectomy.Dig Dis Sci.1982272252307075421
- GreenblattDJ.DivollMK.AbernethyDR.et al.Age and gender effects on chlordiazepoxide kinetics: relation to antipyrine disposition.Pharmacology.1989383273342762375
- DivollM.GreenblattDJ.HarmatzJS.ShaderRl.Effect of age and gender on disposition of temazepam.J Pharm Sci.198170110411076117653
- GreenblattDJ.HarmatzJS.Von MoltkeLL.et al.Comparative kinetics and response to the benzodiazepine agonists triazolam and Zolpidem: evaluation of sex-dependent differences.J Pharmacol Exp Ther.200029343544310773013
- GreenblattDJ.DivollM.HarmatzJS.ShaderRl.Oxazepam kinetics: effects of age and sex.J Pharmacol Exp Ther.198021 586917452494
- GreenblattDJ.AbernetyDR.LocniskarA.et al.Age, sex, and nitrazepam kinetics: relation to antipyrine disposition.Clin Pharmacol Ther.1985386977034064471
- OchsHR.GreenblattDJ.FriedmanH.et al.Bromazepam pharmacokinetics: influence of age, gender, oral contraceptives, cimetidine, and propranolol.Clin Pharmacol Ther.1987415625702882883
- OchsHR.GreenblattDJ.OttenH.Disposition of oxazepam in relation to age, sex, and cigarette smoking.Klin Wochenschr.1981598999037278081
- YeatesRA.LaufenH.RaderK.LeitoldM.Preliminary study of the pharmacokinetics of desmethyldiazepam administered as drops or tablets.Arzneimittelforschung.1986361381403082341
- GreenblattDJ.AbernetyDR.LocniskarA.et al.Effect of age, gender, and obesity on midazolam kinetics.Anesthesiology.19846127356742481
- DivollM.GreenblattDJ.Effect of age and sex on lorazepam protein binding.1 Pharmi Pharmacol.198234122123
- GreenblattDJ.AllenMD.HarmatzJS.ShaderRl.Diazepam disposition determinants.Clin Pharmacol Ther.1980273013127357789
- GilesHG.SellersEM.NaranjoCA.FreckerRC.GreenblattDJ.Disposition of intravenous diazepam in young men and women.Eur J Clin Pharmacol.1981202072137286038
- MacLeodSM.GilesHG.BengertB.LiuFF.SellersEM.Age- and genderrelated differences in diazepam pharmacokinetics.J Clin Pharmacol.1979191519762252
- KirkwoodC.MooreA.HayesP.DeVaneCL.PeloneroA.Influence of menstrual cycle and gender on alprazolam pharmacokinetics.Clin Pharmacol Ther.1991504044091914376
- GreenblattDJ.ShaderRI.FrankeK.et al.Kinetics of intravenous chlordiazepoxide: sex differences in drug distribution.Clin Pharmacol Ther.197722893903923184
- RobertsRK.DesmondPV.WilkinsonGR.SchenkerS.Disposition of chlordiazepoxide: sex differences and effects of oral contraceptives.Clin Pharmacol Ther.197925826831445949
- RoutledgePA.StargelWW.KitchellBB.BarchowskyA.ShandDG.Sexrelated differences in the plasma protein binding of lignocaine and diazepam.Br J Clin Pharmacol.1981112452507213526
- GilesHG.RobertsEA.OrregoH.SellersEM.Disposition of intravenous propylthiouracil.J Clin Pharmacol.1981214664717334138
- StoehrGP.KrobothPD.JuhlRP.et al.Effect of oral contraceptives on triazolam, temazepam, alprazolam, and lorazepam kinetics.Clin Pharmacol Ther.1984366836906149030
- KrobothPD.SmithRB.StoehrGP.JuhlRP.Pharmacodynamic evaluation of the benzodiazepine-oral contraceptive interaction.Clin Pharmacol Ther.1985385255322865026
- McAuleyJW.FriedmanCI.Influence of endogenous progesterone on alprazolam pharmacodynamics.J Clin Psychopharmacol.19991923323910350029
- RukstalisM.de WitH.Effects of triazolam at three phases of the menstrual cycle.J Clin Psychopharmacol.19991945045810505587
- KamimoriGH.SirisuthN.GreenblattDJ.EddingtonND.The influence of the menstrual cycle on triazolam and indocyanine green pharmacokinetics.J Clin Pharmacol.20004073974410883415
- BaylissPF.CaseDE.Blood level studies with viloxazine hydrochloride in man.Br J Clin Pharmacol.197522092141234502
- MaguireKP.NormanTR.MclntyreI.BurrowsGD.Clinical pharmacokinetics of dothiepin single-dose kinetics in patients and prediction of steadystate concentrations.Clin Pharmacokinet.198381791856851370
- BarbhaiyaRH.ShuklaUA.NatarajanCS.et al.Single- and multiple-dose pharmacokinetics of nefazodone in patients with hepatic cirrhosis.Clin Pharmacol Ther.1995583903987586930
- GreenblattDJ.FriedmanH.BursteinES.et al.Trazodone kinetics: effect of age, gender, and obesity.Clin Pharmacol Ther.1987421932003608351
- LachatreG.PivaC.RicheC.et al.Single-dose pharmacokinetics of amineptine and of its main metabolite in healthy young adults.Fundarn Clin Pharmacol.198931926
- VandelB.VandelS.JounetJM.BlumD.Pharmacokinetics of viloxazine hydrochloride in man.Eur J Drug Metab Pharmacokinet.1982765687067726
- KlamerusKJ.ParkerVD.RudolphRL.DerivanAT.ChiangST.Effects of age and gender on venlafaxine and O-desmethylvenlafaxine pharmacokinetics.Pharmacotherapy.1996169159238888087
- StewartJJ.BerkelHJ.ParishRC.et al.Single-dose pharmacokinetics of bupropion in adolescents: effects of smoking status and gender.J Clin Pharmacol.20014177077811452710
- BarbhaiyaRH.ShuklaUA.GreeneDS.Single-dose pharmacokinetics of nefazodone in healthy young and elderly subjects and in subjects with renal or hepatic impairment.Eur J Clin Pharmacol.1995492212288665999
- BarbhaiyaRH.BuchAB.GreeneDS.A study of the effect of age and gender on the pharmacokinetics of nefazodone after single and multiple doses.J Clin Psychopharmacol.19961619258834414
- RonfeldRA.TremaineLM.WilnerKD.Pharmacokinetics of sertraline and its N-demethyl metabolite in elderly and young male and female volunteers.Clin Pharmacokinet.19973222309068932
- WarringtonSJ.Clinical implications of the pharmacology of sertraline.Int Clin Psychopharmacol.19916(suppl 2)1 121
- HsyuPH.SinghA.GiargiariTD.et al.Pharmacokinetics of bupropion and its metabolites in cigarette smokers versus nonsmokers.J Clin Pharmacol.1997377377439378846
- AmsterdamJD.FawcettJ.QutkinFM.et al.Fluoxetine and norfluoxetine plasma concentrations in major depression: a multicenter study.Am J Psychiatry.19971549639699210747
- WilnerKD.TensfeldtTG.BarisB.et al.Single- and multiple-dose pharmacokinetics of ziprasidone in healthy young and elderly volunteers.Br J Clin Pharmacol.20004915S20S10771449
- SimpsonGM.YadalamKG.LevinsonDF.et al.Single-dose pharmacokinetics of fluphenazine after fluphenazine decanoate administration.J Clin Psychopharmacol.1990104174212286711
- WongSL.CaoG.MackRJ.GrannemanGR.Pharmacokinetics of sertindole in healthy young and elderly male and female subjects.Clin Pharmacol Ther.1997621571649284851
- KellyDL.ConleyRR.TammingaCA.Differential olanzapine plasma concentrations by sex in a fixed-dose study.Schizophr Res.19994010110410593449
- JerlingM.MerleY.MentreF.MalletA.Population pharmacokinetics of clozapine evaluated with the nonparametric maximum likelihood method.Br J Clin Pharmacol.1997444474539384461
- EreshefskyL.SakladSR.WatanabeMD.DavisCM.JannMW.Thiothixene pharmacokinetic interactions: a study of hepatic enzyme inducers, clearance inhibitors, and demographic variables.J Clin Psychopharmacol.1991112963011765572
- CallaghanJT.BergstromRF.PtakLR.BeasleyCM.Olanzapine. Pharmacokinetic and pharmacodynamic profile.Clin Pharmacokinet.19993717719310511917
- LaneHY.ChangYC.ChangWH.et al.Effects of gender and age on plasma levels of clozapine and its metabolites: analyzed by critical statistics.J Clin Psychiatry.199960364010074876
- HaringC.MeiseU.HumpelC.et al.Dose-related plasma levels of clozapine: influence of smoking behaviour, sex and age.Psyche/pharmacology (Berl).198999(suppl)S38S40
- JannMW.CrabtreeBL.PittsWM.LamYWF.CarterJG.Plasma alphaone acid glycoprotein and haloperidol concentrations in schizophrenic patients.Neuropsychobioiogy.1997363236
- FabrazzoM.EspositoG.FuscoR.MajM.Effect of treatment duration on plasma levels of clozapine and N-desmethylclozapine in men and women.Psychopharmacology.19961241972008935816
- KellySJ.OstrowskiNL.WilsonMA.Gender differences in brain and behavior: hormonal and neural bases.Pharmacol Biochem Behav.19996465566410593187
- SchmidtPJ.NiemanLK.DanaceauMA.AdamsLF.RubinowDR.Differential behavioral effects of gonadal steroids in women with and in those without premenstrual syndrome. “Engl J Med.1998338209216
- GlassmanAH.PerelJM.ShostakM.KantorSJ.FleissJL.Clinical implications of imipramine plasma levels for depressive illness.Arch Gen Psychiatry.197734197204843179
- WilsonIC.RabonAM.BuffaloeWJ.Imipramine therapy in depressive syndromes: prediction of therapeutic outcome.Psychosomatics.19678203207
- RaskinA.Age-sex differences in response to antidepressant drugs.J Nerv Ment Dis.19741591201304850465
- FrankE.CarpenterLL.KupferDJ.Sex differences in recurrent depression: are there any that are significant?Am J Psychiatry.198814541453337291
- AbrahamHC.KanterVB.RosenI.StandenJL.A controlled clinical trial of imipramine (tofranil) with out-patients.Br J Psychiatry.196310928629314010726
- ImlahNW.FahyPT.HarringtonJA.A comparison of two antidepressant drugs.Psychopharmacologia.196464724745830964
- AsbergM.CronholmB.SjoqvistF.TuckD.Relationship between plasma level and therapeutic effect of nortriptyline.BMJ.197133313345558186
- WalkerJM.BowenWD.AtkinsST.HemstreetMK.CoyDH.μ-Opiate binding and morphine antagonism by octapeptide analogs of somatostatin.Peptides.198788698752893361
- ResibyN.GramLF.BechP.et al.Imipramine: clinical effects and pharmacokinetic variability.Psychopharmacology.197754263272413143
- KornsteinSG.SchatzbergAF.ThaseME.et al.Gender differences in treatment response to sertraline versus imipramine in chronic depression.Am J Psychiatry.20001571445145210964861
- JoycePR.MulderRT.LutySE.et al.Patterns and predictors of remission, response and recovery in major depression treated with fluoxetine or nortriptyline.Aust Nil Psychiatry.200236384391
- Lewis-HallFC.WilsonMG.TepnerRG.KokeSC.Fluoxetine vs tricyclic antidepressants in women with major depressive disorder.J Womens Health.199763373439201668
- ThaseME.RushAJ.HowlandRH.et al.Double-blind switch study of imipramine or sertraline treatment of antidepressant-resistant chronic depression.Arch Gen Psychiatry.20025923323911879161
- FrankE.ThaseME.SpanierCA.ReynoldsCF.IIIKupferDJ.Gender-specific response to depression treatment.J Gend Specif Med.19992404411252842
- MartenyiF.DossenbachM.MrazK.MetcalfeS.Gender differences in the efficacy of fluoxetine and maprotiline in depressed patients: a doubleblind trial of antidepressants with serotonergic or norepinephrinergic reuptake inhibition profile.Eur Neuropsychopharmacol.20011122723211418283
- BurnsRA.LockT.EdwardsDR.et al.Predictors of response to aminespecific antidepressants.J Affect Disord.199535971068749837
- EntsuahAR.HuangH.ThaseME.Response and remission rates in different subpopulations with major depressive disorder administered venlafaxine, selective serotonin reuptake inhibitors, or placebo.J Clin Psychiatry.20016286987711775046
- QuitkinFM.StewartJW.McGrathPJ.et al.Are there differences between women's and men's antidepressant responses?Am J Psychiatry.20021591848185412411218
- DavidsonJ.PeltonS.Forms of atypical depression and their response to antidepressant drugs.Psychiatry Res.19861787953083445
- MoralesAJ.NolanJJ.NelsonJC.YenSSC.Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age.J Clin Endocrinol Metab.199478136013677515387
- DavidsonJR.GillerEL.ZisookS.HelmsMJ.Predictors of response to monoamine oxidase inhibitors: do they exist?Eur Arch Psychiatry Clin Neurosci.19912411811861824048
- SecundaSK.KatzMM.SwannA.et al.Mania. Diagnosis, state measurement and prediction of treatment response.J Affect Disord.198581131213157719
- VigueraAC.TondoL.BaldessariniRJ.Sex differences in response to lithium treatment.Am J Psychiatry.20001571509151110964872
- VigueraAC.BaldessariniRJ.TondoL.Response to lithium maintenance treatment in bipolar disorders: comparison of women and men.Bipolar Disord.2001324525211903207
- DenberHCB.BirdEG.Chlorpromazine in the treatment of mental illness. IV: final results with analysis of data on 1523 patients.Am J Psychiatry.195711397297813411275
- ChouinardG.AnnableL.Pimozide in the treatment of newly admitted schizophrenic patients.Psychopharmacology.19827613196805002
- HogartyGE.GoldbergSC.SchoolerNR.Drug and sociotherapy in the aftercare of schizophrenic patients. III. Adjustment of nonrelapsed patients.Arch Gen Psychiatry.1974316096184374156
- GoldbergSC.SchollerNR.DavidsonEM.KayceMM.Sex and race differences in response to drug treatment among schizophrenics.Psychopharmacologia.1966931475989102
- KolakowskaT.WilliamsA0.JamborK.ArdernM.Schizophrenia with good and poor outcome. III. Neurological “soft” signs, cognitive impairment and their clinical significance.Br J Psychiatry.19851463483574016437
- MeltzerHY.BuschDA.FangVS.Serum neuroleptic and prolactin levels in schizophrenic patients and clinical response.Psychiatry Res.198392712836580660
- RobinsonDG.WoernerMG.AlvirJM.et al.Predictors of treatment response from a first episode of schizophrenia or schizoaffective disorder.Am J Psychiatry.199915654454910200732
- GoldsteinJM.CohenLS.HortonNJ.et al.Sex differences in clinical response to olanzapine compared with haloperidol.Psychiatry Res.2002110273712007591
- GoldsteinMJ.RodnickEH.EvansJR.MayPR.SteinbergMR.Drug and family therapy in the aftercare of acute schizophrenics.Arch Gen Psychiatry.19783511691177211983
- LieberrnanJ.JodyD.GeislerS.et al.Time course and biologic correlates of treatment response in first-episode schizophrenia.Arch Gen Psychiatry.1993503693768098203
- SzymanskiS.LieberrnanJA.AlvirJM.et al.Gender differences in onset of illness, treatment response, course, and biologic indexes in first-episode schizophrenic-patients.Am J Psychiatry.19951526987037726309
- GlickM.MazureCM.BowersMB.ZiglerE.Premorbid social competence and the effectiveness of early neuroleptic treatment.Compr Psychiatry.1993343964017907536
- PinalsDA.MalhotraAK.MissarCD.PickarD.BreierA.Lack of gender differences in neuroleptic response in patients with schizophrenia.Schizophr Res.1996222152229000318
- LabelleA.LightM.DunbarF.Risperidone treatment of outpatients with schizophrenia: no evidence of sex differences in treatment response.Can J Psychiatry.20014653454111526810
- JesteDV.LinnoilaM.WagnerRL.WyattRJ.Serum neuroleptic concentrations and tardive dyskinesia.Psychopharmacology.1982763773806126895
- SzymanskiS.LieberrnanJ.PollackS.et al.Gender differences in neuroleptic nonresponsive clozapine-treated schizophrenics.Biol Psychiatry.1996392492548645771
- LieberrnanJA.KaneJM.SaffermanAZ.et al.Predictors of response to clozapine.J Clin Psychiatry.1994551261287961556
- SimpsonGM.JosiassenRC.StanillaJK.et al.Double-blind study of clozapine dose response in chronic schizophrenia.Am J Psychiatry.19991561744175010553738
- YoungMA.MeltzerHY.The relationship of demographic, clinical, and outcome variables to neuroleptic treatment requirements.Schizophr Bull.19806881016102797
- PerryPJ.LundBC.SangerT.BeasleyC.Olanzapine plasma concentrations and clinical response: acute phase results of the North American Olanzapine Trial.J Clin Psychopharmacol.200121142011199942
- ZitoJM.CraigTJ.WanderlingJ.SiegelC.Pharmaco-epidemiology in 136 hospitalized schizophrenic patients.Am J Psychiatry.19871447787823592000
- MaghariousW.GoffDC.ArnicoE.Relationship of gender and menstrual status to symptoms and medication side effects in patients with schizophrenia.Psychiatry Res.1998771591669707298
- JesteDV.LindamerLA.EvansJ.LacroJP.Relationship of ethnicity and gender to schizophrenia and pharmacology of neuroleptics.Psychopharmacol Bull.1996322432518783894
- ChouinardG.AnnableL.SteinbergS.A controlled clinical trial of fluspirilene, a long-acting injectable neuroleptic, in schizophrenic patients with acute exacerbation.J Clin Psychopharmacol.1986621263512622
- Riecher-RosslerA.HafnerH.Schizophrenia and oestrogens - is there an association?Eur Arch Psychiatry Clin Neurosci.19932423233288323981
- SalokangasRK.Gender and the use of neuroleptics in schizophrenia. Further testing of the oestrogen hypothesis.Schizophr Res.1995167167547647
- SeemanMV.Interaction of sex, age and neuroleptic dose.Compr Psychiatry.1983241251286133698
- Riecher-RosslerA.HafnerH.Gender aspects in schizophrenia: bridging the border between social and biological psychiatry.Acta Psychiatr Scand Suppl.2000102586211261642
- Committee on Understanding the Biology of Sex and Gender DifferencesExploring the Biological Contributions to Human Health: Does Sex Matter?Washington, DC: National Academy Press200118
- CaspiA.SugdenK.MoffittTE.et al.Influence of life stress on depression: moderation by a polymorphism in the5-HTT gene. Science.2003301291293