REFERENCES

• BrainSeq: A Human Brain Genomics Consortium. BrainSeq: neurogenomics to drive novel target discovery for neuropsychiatric disorders.Neuron.20158861078108326687217
   PubMed Web of Science ®Google Scholar
• SweattJD.Experience-dependent epigenetic modifications in the central nervous system.Biol Psychiatry.200965319119719006788
   PubMed Web of Science ®Google Scholar
• Baker-AndresenD.RatnuVS.BredyTW.Dynamic DNA methylation: a prime candidate for genomic metaplasticity and behavioral adaptation.Trends Neurosci.201336131323041052
   PubMed Web of Science ®Google Scholar
• SweattJD.The emerging field of neuroepigenetics.Neuron.201380362463224183015
   PubMed Web of Science ®Google Scholar
• MooreDS.The Developing Genome: An Introduction to Behavioral Epigenetics. New York, NY: Oxford University Press;2015
   Google Scholar
• FrancisRC.Epigenetics: How Environment Shapes Our Genes. New York, NY: Norton;2012
   Google Scholar
• MeaneyMJ.SzyfM.Environmental programming of stress responses through DNA methylation: life at the interface between a dynamic environment and a fixed genome.Dialogues Clin Neurosci.20057210312316262207
   PubMedGoogle Scholar
• WoodMA.HawkJD.AbelT.Combinatorial chromatin modifications and memory storage: a code for memory?Learn Mem.200613324124416741277
   PubMed Web of Science ®Google Scholar
• LevensonJM.SweattJD.Epigenetic mechanisms in memory formation.Nat Rev Neurosci.20056210811815654323
   PubMed Web of Science ®Google Scholar
• HoustonI.PeterCJ.MitchellA.et alEpigenetics in the human brain.Neuropsychopharmacology201338118319722643929
   PubMed Web of Science ®Google Scholar
• JiangY.LangleyB.LubinFD.et alEpigenetics in the nervous system.J Neurosci.20088461175311759
   Google Scholar
• CrickF.Memory and molecular turnover.Nature.198431259901016504122
   PubMed Web of Science ®Google Scholar
• GraffJ.MansuyIM.Epigenetic codes in cognition and behaviour.Behav Brain Res.20081921708718353453
   PubMed Web of Science ®Google Scholar
• BarrettRM.WoodMA.Beyond transcription factors: the role of chromatin modifying enzymes in regulating transcription required for memory.Learn Mem.200815746046718583646
   PubMed Web of Science ®Google Scholar
• ZovkicIB.PaulukaitisBS.DayJJ.EtikalaDM.SweattJD.Histone H2A.Z subunit exchange controls consolidation of recent and remote memory.Nature.2014515752858258625219850
   PubMed Web of Science ®Google Scholar
• KorzusE.RosenfeldMG.MayfordM.CBP histone acetyltransferase activity is a critical component of memory consolidation.Neuron.200442696197215207240
   PubMed Web of Science ®Google Scholar
• LevensonJM.O'RiordanKJ.BrownKD.et alRegulation of histone acetylation during memory formation in the hippocampus.J Biol Chem.200427939405454055915273246
   PubMed Web of Science ®Google Scholar
• MillerCA.SweattJD.Covalent modification of DNA regulates memory formation.Neuron.200753685786917359920
   PubMed Web of Science ®Google Scholar
• HellerEA.CatesHM.PenaCJ.et alLocus-specific epigenetic remodeling controls addiction- and depression-related behaviors.Nat Neurosci.201417121720172725347353
   PubMed Web of Science ®Google Scholar
• TsankovaNM.BertonO.RenthalW.et alSustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action.Nat Neurosci.20069451952516501568
   PubMed Web of Science ®Google Scholar
• KumarA.ChoiKH.RenthalW.et alChromatin remodeling is a key mechanism underlying cocaine-induced plasticity in striatum.Neuron.200548230331416242410
   PubMed Web of Science ®Google Scholar
• MeaneyMJ.SzyfM.Environmental programming of stress responses through DNA methylation: life at the interface between a dynamic environment and a fixed genome.Dialogues Clin Neurosci.20057210312316262207
   PubMedGoogle Scholar
• WeaverIC.ChampagneFA.BrownSE.et alReversal of maternal programming of stress responses in adult offspring through methyl supplementation: altering epigenetic marking later in life.J Neurosci.20052547110451105416306417
   PubMed Web of Science ®Google Scholar
• AlarconJM.MalleretG.TouzaniK.et alChromatin acetylation, memory, and LTP are impaired in CBP+/- mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration.Neuron.200442694795915207239
   PubMed Web of Science ®Google Scholar
• AbdolmalekyHM.ChengK.RussoA.et alHypermethylation of the reelin (RELN) promoter in the brain of schizophrenic patients: a preliminary report.Am J Med Genet B Neuropsychiatr Genet.2005134B1606615717292
   PubMed Web of Science ®Google Scholar
• AkbarianS.HuangHS.Molecular and cellular mechanisms of altered GAD1/GAD67 expression in schizophrenia and related disorders.Brain Res Rev.200652229330416759710
   PubMedGoogle Scholar
• BorgholN.SudermanM.McArdleW.et alAssociations with early-life socio-economic position in adult DNA methylation.Int J Epidemiol.2012411627422422449
   PubMed Web of Science ®Google Scholar
• ChahrourM.JungSY.ShawC.et alMeCP2, a key contributor to neurological disease, activates and represses transcription.Science.200832058801224122918511691
   PubMed Web of Science ®Google Scholar
• ChenY.DongE.GraysonDR.Analysis of the GAD1 promoter: transacting factors and DNA methylation converge on the 5' untranslated region.Neuropharmacology.2011607-81075108720869372
   PubMed Web of Science ®Google Scholar
• CostaE.DavisJM.DongE.et alA GABAergic cortical deficit dominates schizophrenia pathophysiology.Crit Rev Neurobiol.2004161-212315581395
   PubMedGoogle Scholar
• DaviesMN.VoltaM.PidsleyR.et alFunctional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood.Genome Biol.2012136R4322703893
   PubMed Web of Science ®Google Scholar
• DayJJ.SweattJD.Epigenetic mechanisms in cognition.Neuron.201170581382921658577
   PubMed Web of Science ®Google Scholar
• EastwoodSL.HarrisonPJ.Interstitial white matter neurons express less reelin and are abnormally distributed in schizophrenia: towards an integration of molecular and morphologic aspects of the neurodevelopmental hypothesis.Mol Psychiatry.200389769,82183112931209
   PubMed Web of Science ®Google Scholar
• EssexMJ.Thomas BoyceW.HertzmanC.et alEpigenetic vestiges of early developmental adversity: childhood stress exposure and DNA methylation in adolescence.Child Dev.2011841587521883162
   PubMed Web of Science ®Google Scholar
• FragaMF.BallestarE.PazMF.et alEpigenetic differences arise during the lifetime of monozygotic twins.Proc Natl Acad Sci USA.200510230106041060916009939
   PubMed Web of Science ®Google Scholar
• GluckmanPD.HansonMA.Living with the past: evolution, development, and patterns of disease.Science.200430556911733173615375258
   PubMed Web of Science ®Google Scholar
• GraysonDR.JiaX.ChenY.et alReelin promoter hypermethylation in schizophrenia.Proc Natl Acad Sci U S A.2005102269341934615961543
   PubMed Web of Science ®Google Scholar
• HuangHS.AkbarianS.GAD1 mRNA expression and DNA methylation in prefrontal cortex of subjects with schizophrenia.PLoS One.200728e80917726539
   PubMed Web of Science ®Google Scholar
• HuangHS.MatevossianA.WhittleC.et alPrefrontal dysfunction in schizophrenia involves mixed-lineage leukemia 1-regulated histone methylation at GABAergic gene promoters.J Neurosci.20072742112541126217942719
   PubMed Web of Science ®Google Scholar
• KaminskyZA.TangT.WangSC.et alDNA methylation profiles in monozygotic and dizygotic twins.Nat Genet.200941224024519151718
   PubMed Web of Science ®Google Scholar
• MazeI.FengJ.WilkinsonMB.SunHS.ShenL.NestlerEJ.Cocaine dynamically regulates heterochromatin and repetitive element unsilencing in nucleus accumbens.Proc Natl Acad Sci U S A.201110873035304021300862
   PubMed Web of Science ®Google Scholar
• McGowanPO.SasakiA.D'AlessioAC.et alEpigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse.Nat Neurosci.200912334234819234457
   PubMed Web of Science ®Google Scholar
• MeaneyMJ.Ferguson-SmithAC.Epigenetic regulation of the neural transcriptome: the meaning of the marks.Nat Neurosci.201013111313131820975754
   PubMed Web of Science ®Google Scholar
• MillJ.DempsterE.CaspiA.WilliamsB.MoffittT.CraigI.Evidence for monozygotic twin (MZ) discordance in methylation level at two CpG sites in the promoter region of the catechol-O-methyltransferase (COMT) gene.Am J Med Genet B Neuropsychiatr Genet.2006141B442142516583437
   PubMed Web of Science ®Google Scholar
• NgJW.LauraM.BarrettLM.et alThe role of longitudinal cohort studies in epigenetic epidemiology: challenges and opportunities.Genome Biol.201213624622747597
   PubMed Web of Science ®Google Scholar
• PetronisA.Epigenetics as a unifying principle in the aetiology of complex traits and diseases.Nature.2010465729972172720535201
   PubMed Web of Science ®Google Scholar
• RenthalW.MazeI.KrishnanV.et alHistone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli.Neuron.200756351752917988634
   PubMed Web of Science ®Google Scholar
• SiegmundKD.ConnorCM.CampanM.et alDNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons.PLoS One.200729e89517878930
   PubMed Web of Science ®Google Scholar
• TangB.DeanB.ThomasEA.Disease- and age-related changes in histone acetylation at gene promoters in psychiatric disorders.Transl Psychiatry.20111e6422832356
   PubMed Web of Science ®Google Scholar
• TyrkaAR.PrinceLH.MarsitC.WaltersOC.CarpenterLL.Childhood adversity and epigenetic modulation of the leukocyte glucocorticoid receptor: preliminary findings in healthy adults.PloS One.201271e3014822295073
   PubMed Web of Science ®Google Scholar
• NestlerEJ.Epigenetic mechanisms of drug addiction.Neuropharmacology.201476pt B25926823643695
   PubMed Web of Science ®Google Scholar
• AkbarianS.Epigenetics of schizophrenia.Curr Top Behav Neurosciences.20104611628
   PubMedGoogle Scholar
• JaffeAE.GaoY.Deep-SoboslayA.et alMapping DNA methylation across development, genotype and schizophrenia in the human frontal cortex.Nat Neurosci.2016191404726619358
   PubMed Web of Science ®Google Scholar
• WocknerLF.NobleEP.LawfordBR.et alGenome-wide DNA methylation analysis of human brain tissue from schizophrenia patients.Transl Psychiatry.20144e33924399042
   PubMed Web of Science ®Google Scholar
• GraysonDR.GuidottiA.The dynamics of DNA methylation in schizophrenia and related psychiatric disorders.Neuropsychopharmacology.201338113816622948975
   PubMed Web of Science ®Google Scholar
• KumarG.ClarkSL.McClayJL.et alRefinement of schizophrenia GWAS loci using methylome-wide association data.Hum Genet.201513417787
   Web of Science ®Google Scholar
• GavinDP.FloreaniC.Epigenetics of schizophrenia: an open and shut case.Int Rev Neurobiol.201411515520125131545
   PubMed Web of Science ®Google Scholar
• GuidottiA.AutaJ.DavisJM.et alToward the identification of peripheral epigenetic biomarkers of schizophrenia.J Neurogenet.20142812415224702539
   PubMedGoogle Scholar
• AbdolmalekyHM.NohesaraS.GhadirivasfiM.et alDNA hypermethylation of serotonin transporter gene promoter in drug naive patients with schizophrenia.Schizophr Res.20141522-337338024411530
   PubMed Web of Science ®Google Scholar
• AbergKA.McClayJL.NerellaS.et alMethylome-wide association study of schizophrenia: identifying blood biomarker signatures of environmental insults.JAMA. Psychiatry.201471325526424402055
   PubMed Web of Science ®Google Scholar
• AutaJ.SmithRC.DongE.et alDNA-methylation gene network dysregulation in peripheral blood lymphocytes of schizophrenia patients.Schizophr Res.2013150131231823938174
   PubMed Web of Science ®Google Scholar
• DayJJ.KennedyAJ.SweattJD.DNA methylation and its implications and accessibility for neuropsychiatric therapeutics.Annu Rev Pharmacol Toxicol.20155559161125340930
   PubMed Web of Science ®Google Scholar
• FrankeB.SteinJL.RipkeS.et alGenetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept.Nat Neurosci.201619342043126854805
   PubMed Web of Science ®Google Scholar
• ClementzBA.SweeneyJA.HammJP.et alIdentification of distinct psychosis biotypes using brain-based biomarkers.Am J Psychiatry.2016173437338426651391
   PubMed Web of Science ®Google Scholar
• CuthbertBN.InselTR.Toward new approaches to psychotic disorders: the NIMH Research Domain Criteria project.Schizophr Bull.20103661061106220929969
   PubMed Web of Science ®Google Scholar
• InselT.CuthbertB.GarveyM.et alResearch domain criteria (RDoC): toward a new classification framework for research on mental disorders.Am J Psychiatry.2010167774875120595427
   PubMed Web of Science ®Google Scholar
• LombardiLM.BakerSA.ZoghbiHY.MeCP2 disorders: from the clinic to mice and back.J Clin Invest.201512582914292326237041
   PubMed Web of Science ®Google Scholar