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Individual differences in the neuropsychopathology of addiction

Diferencias individuales en la neuropsicopatología de la adicción

Différences individuelles dans la neuro-psychopathologie de l'addiction

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REFERENCES

  • KoobGF.Le MoalM.Drug abuse: heclonic homeostaticdysregulation.Science.1997278533552589311926
  • KoobGF.VolkowND.Neurobiology of addiction: a neurocircuitry analysis.Lancet Psychiatry.20163876077327475769
  • KoobGF.Le MoalM.Drug addiction, dysregulation of reward, and allostasis.Neuropsychopharmacology.20012429712911120394
  • HeiligM.KoobGF.A key role for corticotropin-releasing factor in alcohol dependence.Trends Neurosci.200730839940617629579
  • KoobGF.Le MoalM.Addiction and the brain antireward system.Annu Rev Psychol.200859295318154498
  • KoobGF.Theoretical frameworks and mechanistic aspects of alcohol addiction: alcohol addiction as a reward deficit disorder.Curr Top Behav Neurosci.2013330
  • MoellerFG.BarrattES.DoughertyDM.SchmitzJM.SwannAC.Psychiatric aspects of impulsivity.Am J Psychiatry.2001158111783179311691682
  • BerlinGS.HollanderE.Compulsivity, impulsivity, and the DSM-5 process.CNS Spectr.2014191626824229702
  • SkinnerBF.The Behavior of Organisms: An Experimental Analysis. New York, NY: Apple-Century-Crofts. 1938
  • HebbDO.Textbook of Psychology, 3rd edition. Philadelphia, PA: WB Saunders.1972
  • SolomonRL.CorbitJD.An opponent-process theory of motivation: 1 . Temporal dynamics of affect.Psychol Rev.19748121191454817611
  • LaulinJP.CelerierE.LarcherA.Le Moal M Simonnet G Opiate tolerance to daily heroin administration: an apparent phenomenon associated with enhanced pain sensitivity.Neuroscience.199989363163610199599
  • KoobGF.BloomFE.Cellular and molecular mechanisms of drug dependence.Science.198824248797157232903550
  • KoobGF.EverittBJ.RobbinsTW.Reward, motivation, and addiction. In: Squire LG, Berg D, Bloom FE, Du Lac S, Ghosh A, Spitzer N, eds.Fundamental Neuroscience. 3rd edition. Amsterdam, the Netherlands: Academic Press.20089871016
  • WiseRA.The role of reward pathways in the development of drug dependence.Pharmacol Then.1987351-2227263
  • RobinsonTE.BerridgeKC.The neural basis of drug craving: an incentive-sensitization theory of addiction.Brain Res Rev.19931832472918401595
  • GoldsteinRZ.CraigAD.BecharaA.et alThe neurocircuitry of impaired insight in drug addiction.Trends Cogn Sci.200913937238019716751
  • MitchellJM.O'NeilJP.JanabiM.MarksSM.JagustWJ.Fields HL Alcohol consumption induces endogenous opioid release in the human orbitofrontal cortex and nucleus accumbensSci Transl Med.20124116116ra116
  • VolkowND.FowlerJS.WangGJ.The addicted human brain: insights from imaging studies.J Clin Invest.2003111101444145112750391
  • EttenbergA.PettitHO.BloomFE.KoobGF.Heroin and cocaine intravenous self-administration in rats: mediation by separate neural systems.Psychopharmacology (Berl).19827832042096296898
  • PettitHO.EttenbergA.BloomFE.KoobGF.Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats.Psychopharmacology (Berl).19848421671736438676
  • RassnickS.StinusL.KoobGF.The effects of 6-hydroxydopamine lesions of the nucleus accumbens and the mesolimbic dopamine system on oral self-administration of ethanol in the rat.Brain Res.1993623116248221085
  • SchultzW.StaufferWR.LakA.The phasic dopamine signal maturing: from reward via behavioural activation to formal economic utility.Curr Opin Neurobiol.20174313914828390863
  • RobbinsTW.Relationship between reward-enhancing and stereotypical effects of psychomotor stimulant drugs.Nature.19762645581575912471
  • SchultzW.DayanP.MontaguePR.A neural substrate of prediction and reward.Science.19972755306159315999054347
  • SchultzW.Dopamine reward prediction error coding.Dialogues Clin Neurosci.2016181233227069377
  • RobinsonMJ.FischerAM.AhujaA.LesserEN.ManiatesH.Roles of “wanting” and “liking” in motivating behavior: gambling, food, and drug addictions.Curr Top Behav Neurosci.20162710513626407959
  • BerridgeKC.RobinsonTE.Liking, wanting, and the incentive-sensitization theory of addiction.Am Psychol.201671867067927977239
  • BoileauI.DagherA.LeytonM.et alModeling sensitization to stimulants in humans: an [11C]raclopride/positron emission tomography study in healthy men.Arch Gen Psychiatry.200663121386139517146013
  • UnglessMA.WhistlerJL.MalenkaRC.BonciA.Single cocaine exposure in vivo induces long-term potentiation in dopamine neurons.Nature.2001411683758358711385572
  • HausknechtK.ShenYL.WangRX.Haj-DahmaneS.ShenRY.Prenatal ethanol exposure persistently alters endocannabinoid signaling and endocannabinoid-mediated excitatory synaptic plasticity in ventral tegmental area dopamine neurons.J Neurosci.201737245798580828476947
  • BocklischC.PascoliV.WongJC.et alCocaine disinhibits dopamine neurons by potentiation of GABA transmission in the ventral tegmental area.Science.201334161531521152524072923
  • MaoD.GallagherK.McGeheeDS.Nicotine potentiation of excitatory inputs to ventral tegmental area dopamine neurons.J Neurosci.201131186710672021543600
  • ChenBT.BowersMS.MartinM.et alCocaine but not natural reward self-administration nor passive cocaine infusion produces persistent LTP in the VTA.Neuron.200859228829718667156
  • PanB.HillardCJ.LiuQS.Endocannabinoid signaling mediates cocaine-induced inhibitory synaptic plasticity in midbrain dopamine neurons.J Neurosci.20082861385139718256258
  • SartiF.BorglandSL.KharaziaVN.BonciA.Acute cocaine exposure alters spine density and long-term potentiation in the ventral tegmental area.Eur J Neurosci.200726374975617686047
  • MelisM.CatnariniR.UnglessMA.BonciA.Long-lasting potentiation of GABAergic synapses in dopamine neurons after a single in vivo ethanol exposure.J Neurosci.20022262074208211896147
  • MansvelderHD.McGeheeDS.Long-term potentiation of excitatory inputs to brain reward areas by nicotine.Neuron.20002723493S710985354
  • CoxSM.YauY.LarcherK.et alCocaine cue-induced dopamine release in recreational cocaine users.Sci Rep. 2017;7:46665. doi:10.1038/ srep46665.
  • FurlongTM.CorbitLH.BrownRA.BalleineBW.Methamphetamine promotes habitual action and alters the density of striatal glutamate receptor and vesicular proteins in dorsal striatum.Addict Biol. 2017 Jul 14. Epub ahead of print. doi:10.1 1 1 1/adb.1 2534.
  • CorbitLH.NieH.JanakPH.Habitual responding for alcohol depends upon both AMPA and D2 receptor signaling in the dorsolateral striatum.Front Behav Neurosci.2014830125228865
  • PalmS.NylanderI.Dopamine release dynamics change during adolescence and after voluntary alcohol intake.PLoS One.201495e9633724788731
  • FanelliRR.KleinJT.ReeseRM.RobinsonDL.Dorsomedial and dorsolateral striatum exhibit distinct phasic neuronal activity during alcohol self-administration in rats.Eur J Neurosci.20133842637264823763702
  • CorbitLH.NieH.JanakPH.Habitual alcohol seeking: time course and the contribution of subregions of the dorsal striatum.Biol Psychiatry.201272538939522440617
  • BelinD.EverittBJ.Cocaine seeking habits depend upon dopamine-dependent serial connectivity linking the ventral with the dorsal striatum.Neuron.200857343244118255035
  • VanderschurenLJ.Di CianoP.EverittBJ.Involvement of the dorsal striatum in cue-controlled cocaine seeking.J Neurosci.200525388665867016177034
  • ItoR.DalleyJW.RobbinsTW.EverittBJ.Dopamine release in the dorsal striatum during cocaine-seeking behavior under the control of a drug-associated cue.J Neurosci.200222146247625312122083
  • WilluhnI.BurgenoLM.GroblewskiPA.PhillipsPE.Excessive cocaine use results from decreased phasic dopamine signaling in the striatum.Nat Neurosci.201417570470924705184
  • WilluhnI.BurgenoLM.EverittBJ.PhillipsPE.Hierarchical recruitment of phasic dopamine signaling in the striatum during the progression of cocaine use.Proc Natl Acad Sci U S A.201210950207032070823184975
  • CaineSB.ThomsenM.GabrielKl.et alLack of self-administration of cocaine in dopamine D1 receptor knock-out mice.J Neurosci.20072748131401315018045908
  • CaineSB.NegusSS.MelloNK.et alRole of dopamine D2-like receptors in cocaine self-administration: studies with D2 receptor mutant mice and novel D2 receptor antagonists.J Neurosci.20022272977298811923462
  • RobertsAJ.McDonaldJS.HeyserCJ.et alμ-Opioid receptor knockout mice do not self-administer alcohol.J Pharmacol Exp Ther.200029331002100810869404
  • KallupiM.ScuppaG.de GuglielmoG.et alGenetic deletion of the nociceptin/orphanin FQ receptor in the rat confers resilience to the development of drug addiction.Neuropsychopharmacology.201742369570627562376
  • CunninghamKA.AnastasioNC.Serotonin at the nexus of impulsivity and cue reactivity in cocaine addiction.Neuropharmacology.201476pt B46047823850573
  • VashchinkinaE.PanhelainenA.Aitta-ahoT.KorpiER.GABAa receptor drugs and neuronal plasticity in reward and aversion: focus on the ventral tegmental area.Front Pharmacol.2014525625625505414
  • BuczynskiMW.HermanMA.HsuKL.et alDiacylglycerol lipase disinhibits VTA dopamine neurons during chronic nicotine exposure.Proc Natl Acad Sci U S A.201611341086109126755579
  • MelisM.SaghedduC.De FeliceM.et alEnhanced endocannabinoid-mediated modulation of rostromedial tegmental nucleus drive onto dopamine neurons in Sardinian alcohol-preferring rats.J Neurosci.20143438127161272425232109
  • Rashidy-PourA.PahlevaniP.VaziriA.et alInvolvement of CB1 receptors in the ventral tegmental area in the potentiation of morphine rewarding properties in acquisition but not expression in the conditioned place preference model.Behav Brain Res.201324725926723511249
  • MalinenH.HyytiaP.Ethanol self-administration is regulated by CB1 receptors in the nucleus accumbens and ventral tegmental area in alcohol-preferring AA rats.Alcohol Clin Exp Res.200832111976198318782338
  • HyytiaP.KoobGF.GABAA receptor antagonism in the extended amygdala decreases ethanol self-administration in rats.Eur J Pharmacol.19952831-31511597498304
  • KoobGF.Le Moal M Plasticity of reward neurocircuitry and the “dark side” of drug addiction.Nat Neurosci.20058111442144416251985
  • WeissF.MarkouA.LorangMT.KoobGF.Basal extracellular dopamine levels in the nucleus accumbens are decreased during cocaine withdrawal after unlimited-access self-administration.Brain Res.199259323143181450939
  • MartinezD.NarendranR.FoltinRW.et alAmphetamine-induced dopamine release: markedly blunted in cocaine dependence and predictive of the choice to self-administer cocaine.Am J Psychiatry.2007164462262917403976
  • VolkowND.WangGJ.TelangF.et alProfound decreases in dopamine release in striatum in detoxified alcoholics: possible orbitofrontal involvement.J Neurosci.20072746127001270618003850
  • VolkowND.TomasiD.WangGJ.et alStimulant-induced dopamine increases are markedly blunted in active cocaine abusers.Mol Psychiatry.20141991037104324912491
  • VolkowND.WangGJ.FowlerJS.et alDecreased striatal dopaminergic responsiveness in detoxified cocaine-dependent subjects.Nature.199738666278308339126741
  • StinusL.KoobGF.Le MoalM.Nucleus accumbens and amygdala are possible substrates for the aversive stimulus effects of opiate withdrawal.Neuroscience.19903737677732247222
  • MinkowskiCP.EpsteinD.FrostJJ.GorelickDA.Differential response to IV carfentanil in chronic cocaine users and healthy controls.Addict Biol.201217114915521054687
  • DavidsonM.ShanleyB.WilceP.Increased NMDA-induced excitability during ethanol withdrawal: a behavioural and histological study.Brain Res.1995674191967773699
  • DahchourA.de WitteP.BoloN.et alCentral effects of acamprosate: Part 1. Acamprosate blocks the glutamate increase in the nucleus accumbens microdialysate in ethanol withdrawn rats.Psychiatry Res.19988221071149754453
  • DaniJA.HeinemannS.Molecular and cellular aspects of incotine abuse.Neuron.19961659059088630247
  • ToluS.EddineR.MartiF.et alCo-activation of VTA DA and GABA neurons mediates nicotine reinforcement.Mol Psychiatry.201318338239322751493
  • WalkerBM.KoobGF.Pharmacological evidence for a motivational role of k-opioid systems in ethanol dependence.Neuropsychopharmacology.200833364365217473837
  • SchlosburgJE.Whitfield TWJr.ParkPE.et alLong-term antagonism of opioid receptors prevents escalation of and increased motivation for heroin intake.J Neurosci.20133349193841939224305833
  • Whitfield TWJr.SchlosburgJ.WeeS.et alOpioid receptors in the nucleus accumbens shell mediate escalation of methamphetamine intake.J Neurosci.201535104296430525762676
  • KoobGF.BuckCL.CohenA.et alAddiction as a stress surfeit disorder.Neuropharmacology.201476pt B37038223747571
  • RivierC.BruhnT.ValeW.Effect of ethanol on the hypothalamic-pituitary-adrenal axis in the rat: role of corticotropin-releasing factor (CRF).J Pharmacol Exp Then.19842291127131
  • Merlo-PichE.LorangM.YeganehM.et alIncrease of extracellular corticotropin-releasing factor-like immunoreactivity levels in the amygdala of awake rats during restraint stress and ethanol withdrawal as measured by microdialysis.J Neurosci.1995158543954477643193
  • KoobGF.HeinrichsSC.MenzaghiF.PichEM.BrittonKT.Corticotropin releasing factor, stress and behavior.Semin Neurosci.199464221229
  • RasmussenDD.BoldtBM.BryantCA.MittonDR.LarsenSA.WilkinsonCW.Chronic daily ethanol and withdrawal: 1. Long-term changes in the hypotha lamo-pituitary-adrena I axis.Alcohol Clin Exp Res.200024121836184911141043
  • OliveMF.KoenigHN.NanniniMA.HodgeCW.Elevated extracellular CRF levels in the bed nucleus of the stria terminalis during ethanol withdrawal and reduction by subsequent ethanol intake.Pharmacol Biochem Behav.199360512532
  • DelfsJM.ZhuY.DruhanJP.Aston-JonesG.Noradrenaline in the ventral forebrain is critical for opiate withdrawal-induced aversion.Nature.2000403676843043410667795
  • KoobGF.Brain stress systems in the amygdala and addiction.Brain Res.20091293617519332030
  • HeimerL.AlheidG.Piecing together the puzzle of basal forebrain anatomy. In: Napier TC, Kalivas PW, Hanin I, eds.The Basal Forebrain: Anatomy to Function. New York, NY: Plenum Press. Advances in Experimental Medicine and Biology; vol 295.1991142
  • RichterRM.WeissF.In vivo CRF release in rat amygdala is increased during cocaine withdrawal in self-administering rats.Synapse.199932425426110332801
  • GeorgeO.GhozlandS.AzarMR.et alCRF-CRF, system activation mediates withdrawal-induced increases in nicotine self-administration in nicotine-dependent rats.Proc Natl Acad Sci USA.200710443171981720317921249
  • SarnyaiZ.BiroE.GardiJ.VecsernyesM.JuleszJ.TelegdyG.Brain corticotropin-releasing factor mediates “anxiety-like” behavior induced by cocaine withdrawal in rats.Brain Res.19956751-289977796157
  • BassoAM.SpinaM.RivierJ.ValeW.KoobGF.Corticotropin-releasing factor antagonist attenuates the “anxiogenic-like” effect in the defensive burying paradigm but not in the elevated plus-maze following chronic cocaine in rats.Psychopharmacology (Berl).19991451213010445369
  • CohenA.TreweekJ.EdwardsS.et alExtended access to nicotine leads to a CRF, receptor dependent increase in anxiety-like behavior and hyperalgesia in rats.Addict Biol.2015201566823869743
  • GriederTE.HermanMA.ContetC.et alVTA CRF neurons mediate the aversive effects of nicotine withdrawal and promote intake escalation.Nat Neurosci.201417121751175825402857
  • RassnickS.HeinrichsSC.BrittonKT.KoobGF.Microinjection of a corticotropin-releasing factor antagonist into the central nucleus of the amygdala reverses anxiogenic-like effects of ethanol withdrawal.Brain Res.1993605125328467387
  • HeinrichsSC.MenzaghiF.SchulteisG.KoobGF.StinusL.Suppression of corticotropin-releasing factor in the amygdala attenuates aversive consequences of morphine withdrawal.Behav Pharmacol.199561748011224314
  • SchulteisG.MarkouA.GoldLH.StinusL.KoobGF.Relative sensitivity to naloxone of multiple indices of opiate withdrawal: a quantitative dose-response analysis.J Pharmacol Exp Ther.19942713139113987996451
  • GoedersNE.GuerinGF.Effects of the CRH receptor antagonist CP154,526 on intravenous cocaine self-administration in rats.Neuropsychopharmacology.200023557758611027923
  • GreenwellTN.FunkCK.CottoneP.et alCorticotropin-releasing factor-1 receptor antagonists decrease heroin self-administration in long-, but not short-access rats.Addict Biol.200914213014319291009
  • KwakoLE.SpagnoloPA.SchwandtML.et alThe corticotropin releasing hormone-1 (CRH1) receptor antagonist pexacerfont in alcohol dependence: a randomized controlled experimental medicine study.Neuropsychopharmacology.20154051053106325409596
  • SchwandtML.CortesCR.KwakoLE.et alThe CRF1 antagonist verucerfont in anxious alcohol-dependent women: translation of neuroendocrine, but not of anti-craving effects.Neuropsychopharmacology.201641122818282927109623
  • SpierlingSR.ZorrillaEP.Don't stress about CRF: assessing the translational failures of CRF, antagonists.Psychopharmacology (Berl).20172349101467148128265716
  • Carlezon WAJr.NestlerEJ.NeveRL.Herpes simplex virus-mediated gene transfer as a tool for neuropsychiatric research.Crit Rev Neurobiol.2000141476711253955
  • KoobGF.The dark side of emotion: the addiction perspective.Eur J Pharmacol.2015753738725583178
  • ChavkinC.KoobGF.Dynorphin, dysphoria and dependence: the stress of addiction.Neuropsychopharmacology.2016411373374
  • HikosakaO.The habenula: from stress evasion to value-based decision-making.Nat Rev Neurosci.201011750351320559337
  • MatsumotoM.HikosakaO.Lateral habenula as a source of negative reward signals in dopamine neurons.Nature.200744771481111111517522629
  • FowlerCD.LuQ.JohnsonPM.MarksMJ.KennyPJ.Habenular 5 nicotinic receptor subunit signalling controls nicotine intake.Nature.2011471734059760121278726
  • SalasR.SturmR.BoulterJ.De BiasiM.Nicotinic receptors in the habenulo-interpeduncular system are necessary for nicotine withdrawal in mice.J Neurosci.200929103014301819279237
  • Zhao-SheaR.DeGrootSR.LiuL.et alIncreased CRF signalling in a ventral tegmental area-interpeduncular nucleus-medial habenula circuit induces anxiety during nicotine withdrawal.Nat Commun.201566770
  • BonsonKR.GrantSJ.ContoreggiCS.et alNeural systems and cue-induced cocaine craving.Neuropsychopharmacology.200226337638611850152
  • PelchatML.JohnsonA.ChanR.ValdezJ.RaglandJD.Images of desire: food-craving activation during fMRI.Neuroimage.20042341486149315589112
  • WangZ.FaithM.PattersonF.et alNeural substrates of abstinence-induced cigarette cravings in chronic smokers.J Neurosci.20072751140351404018094242
  • NaqviNH.RudraufD.DamasioH.BecharaA.Damage to the insula disrupts addiction to cigarette smoking.Science.2007315581153153417255515
  • NaqviNH.BecharaA.The hidden island of addiction: the insula.Trends Neurosci.2009321566718986715
  • SanchezMM.YoungLJ.PlotskyPM.InselTR.Autoradiographic and in situ hybridization localization of corticotropin-releasing factor 1 and 2 receptors in nonhuman primate brain.J Comp Neurol.1999408336537710340512
  • GoudriaanAE.De RuiterMB.van den BrinkW.OosterlaanJ.VeltmanDJ.Brain activation patterns associated with cue reactivity and craving in abstinent problem gamblers, heavy smokers and healthy controls: an fMRI study.Addict Biol.201015449150320840335
  • JanesAC.PizzagalliDA.RichardtS.et alBrain reactivity to smoking cues prior to smoking cessation predicts ability to maintain tobacco abstinence.Biol Psychiatry.201067872272920172508
  • JentschJD.TaylorJR.Impulsivity resulting from frontostriatal dysfunction in drug abuse: implications for the control of behavior by reward-related stimuli.Psychopharmacology.1999146437339010550488
  • Oscar-BermanM.HutnerN.Frontal lobe changes after chronic alcohol ingestion. In: Hunt WA, Nixon SJ, eds. Alcohol-Induced Brain Damage. Bethesda, MD: National Institute on Alcohol Abuse and Alcoholism; 1993:121-156. NIAAA Research Monograph; vol 22.
  • VolkowND.WangGJ.FowlerJS.TomasiD.TelangF.Addiction: beyond dopamine reward circuitry.Proc Natl Acad Sci USA.201110837150371504221402948
  • BaldacchinoA.BalfourDJ.PassettiF.HumphrisG.MatthewsK.Neuropsychological consequences of chronic opioid use: a quantitative review and meta-analysis.Neurosci Biobehav Rev.20123692056206822771335
  • LondonED.KohnoM.MoralesAM.BallardME.Chronic methamphetamine abuse and corticostriatal deficits revealed by neuroimaging.Brain Res.20151628pt A17418525451127
  • RobbinsTW.ErscheKD.EverittBJ.Drug addiction and the memory systems of the brain.Ann N Y Acad Sci.2008114112118991949
  • GeorgeO.KoobGF.Individual differences in prefrontal cortex function and the transition from drug use to drug dependence.Neurosci Biobehav Rev.201035223224720493211
  • GeorgeO.MandyamCD.WeeS.KoobGF.Extended access to cocaine self-administration produces long-lasting prefrontal cortex-dependent working-memory impairments.Neuropsychopharmacology.200833102474248218033234
  • GeorgeO.SandersC.FreilingJ.et alRecruitment of medial prefrontal cortex neurons during alcohol withdrawal predicts cognitive impairment and excessive alcohol drinking.Proc Natl Acad Sci USA.201210944181561816123071333
  • RecintoP.SamantAR.ChavezG.et alLevels of neural progenitors in the hippocampus predict memory impairment and relapse to drug seeking as a function of excessive methamphetamine self-administration.Neuropsychopharmacology.20123751275128722205547
  • BriandLA.FlagelSB.SeemanP.RobinsonTE.Cocaine self-administration produces a persistent increase in dopamine D22 receptors.Eur Neuropsychopharmacol.2008 188 55155618284941
  • KoberH.LacadieCM.WexlerBE.MalisonRT.SinhaR.PotenzaMN.Brain activity during cocaine craving and gambling urges: an fMRI study.Neuropsychopharmacology.201641262863726119472
  • LeeJH.LimY.WiederholdBK.GrahamSJ.A functional magnetic resonance imaging (fMRI) study of cue-induced smoking craving in virtual environments.Appl Psychophysiol Biofeedback.20053019520416167185
  • RisingerRC.SalmeronBJ.RossTJ.et alNeural correlates of high and craving during cocaine self-administration using BOLD fMRI.Neuroimage.20052631097110815886020
  • VolkowND.WangGJ.MaY.et alActivation of orbital and medial prefrontal cortex by methylphenidate in cocaine-addicted subjects but not in controls: relevance to addiction.J Neurosci.200525153932393915829645
  • JasinskaAJ.SteinEA.KaiserJ.NaumerMJ.YalachkovY.Factors modulating neural reactivity to drug cues in addiction: a survey of human neuroimaging studies.Neurosci Biobehav Rev.20143811624211373
  • FotrosA.CaseyKF.LarcherK.et alCocaine cue-induced dopamine release in the amygdala and hippocampus: a high-resolution PET [18F]fallypride study in cocaine dependent participants.Neuropsychopharmacology.20133891780178823546387
  • VolkowND.WangGJ.TelangF.et alCocaine cues and dopamine in dorsal striatum: mechanism of craving in cocaine addiction.J Neurosci.200626246583658816775146
  • MilellaMS.FotrosA.GravelP.et alCocaine cue-induced dopamine release in the human prefrontal cortex.J Psychiatry Neurosci.201641532233026900792
  • KoobGF.VolkowND.Neurocircuitry of addiction.Neuropsychopharmacology.20103521723819710631
  • VolkowND.WangGJ.FowlerJS.et alAssociation of methylphenidate-induced craving with changes in right striato-orbitofrontal metabolism in cocaine abusers: implications in addiction.Am J Psychiatry.1999156119269892293
  • GoldsteinRZ.VolkowND.Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications.Nat Rev Neurosci.2011121165266922011681
  • BryceCA.FlorescoSB.Perturbations in effort-related decision-making driven by acute stress and corticotropin-releasing factor.Neuropsychopharmacology.20164182147215926830960
  • VolkowND.FowlerJS.WangGJ.BalerR.TelangF.Imaging dopamine's role in drug abuse and addiction.Neuropharmacology.200956suppl 13818617195
  • ThanosPK.MichaelidesM.UmegakiH.VolkowND.D2R DNA transfer into the nucleus accumbens attenuates cocaine self-administration in rats.Synapse.200862748148618418874
  • GromanSM.LeeB.SeuE.et alDysregulation of D2-mediated dopamine transmission in monkeys after chronic escalating methamphetamine exposure.J Neurosci.201232175843585222539846
  • LoboMK.NestlerEJ.The striatal balancing act in drug addiction: distinct roles of direct and indirect pathway medium spiny neurons.Front Neuroanat.201154121811439
  • VolkowND.MoralesM.The brain on drugs: from reward to addiction.Cell.2015162471272526276628
  • BecharaA.DamasioH.DamasioAR.LeeGP.Different contributions of the human amygdala and ventromedial prefrontal cortex to decision-making.J Neurosci.199919135473548110377356
  • JohnstoneT.van ReekumCM.UrryHL.KalinNH.DavidsonRJ.Failure to regulate: counterproductive recruitment of top-down prefrontal-subcortical circuitry in major depression.J Neurosci.200727338877888417699669
  • ClarkeTK.CristRC.KampmanKM.et alLow frequency genetic variants in the μ-opioid receptor (OPRM1) affect risk for addiction to heroin and cocaine.Neurosci Lett.2013542717523454283
  • WachmanEM.HayesMJ.BrownMS.et alAssociation of OPRM1 and COMT single-nucleotide polymorphisms with hospital length of stay and treatment of neonatal abstinence syndrome.JAMA.2013309171821182723632726
  • ThorgeirssonTE.GudbjartssonDF.SurakkaI.ENGAGEConsortium.et alSequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.Nat Genet.201042544845320418888
  • LevranO.O'HaraK.PelesE.et al ABCB1 (MDR1) genetic variants are associated with methadone doses required for effective treatment of heroin dependence.Hum Mol Genet.200817142219222718424454
  • ThorgeirssonTE.GellerF.SulemP.et alA variant associated with nicotine dependence, lung cancer and peripheral arterial disease.Nature.2008452718763864218385739
  • ChenAC.ManzN.TangY.et alSingle-nucleotide polymorphisms in corticotropin releasing hormone receptor 1 gene (CRHR1) are associated with quantitative trait of event-related potential and alcohol dependence.Alcohol Clin Exp Res.201034698899620374216
  • SchrnidB.BlomeyerD.TreutleinJ.et alInteracting effects of CRHR1 gene and stressful life events on drinking initiation and progression among 19-year-olds.Int J Neuropsychopharmacol.201013670371419607758
  • TreutleinJ.KisslingC.FrankJ.et al Genetic association of the human corticotropin releasing hormone receptor 1 (CRHR1) with binge drinking and alcohol intake patterns in two independent samples.Mol Psychiatry.200611659460216550213
  • WetherillL.SchuckitMA.HesselbrockV.et alNeuropeptide Y receptor genes are associated with alcohol dependence, alcohol withdrawal phenotypes, and cocaine dependence.Alcohol Clin Exp Res.200832122031204018828811
  • BhaskarLV.ThangarajK.KumarKP.PardhasaradhiG.SinghL.RaoVR.Association between neuropeptide Y gene polymorphisms and alcohol dependence: a case-control study in two independent populations.Eur Addict Res.201319630731323652361
  • MutschlerJ.AbbruzzeseE.von der GoltzC.et alGenetic variation in the neuropeptide Y gene promoter is associated with increased risk of tobacco smoking.Eur Addict Res.201218524625222584873