2,095
Views
5
CrossRef citations to date
0
Altmetric
Tumor immunology in head and neck cancers

Prognosis of HPV-positive head and neck cancers: implication of smoking and immunosuppression

, , , &
Article: 25717 | Received 13 Aug 2014, Accepted 14 Oct 2014, Published online: 04 Nov 2014

References

  • Globocan. International Agency for Research on Cancer [cited 2011 May 16]. 2008 Available from: http://globocan.iarc.fr/
  • Grandis JR Pietenpol JA Greenberger JS Pelroy RA Mohla S. . Head and neck cancer: Meeting summary and research opportunities. Cancer Res. 2004;64:8126-9.
  • Shah JP Patel SG . Head and neck surgery and oncology. 2003 New York, NY Mosby
  • Forastiere AA Trotti A. . Radiotherapy and concurrent chemotherapy: A strategy that improves locoregional control and survival in oropharyngeal cancer. J Natl Cancer Inst. 1999;91:2065-6.
  • Denis F Garaud P Bardet E Alfonsi M Sire C Germain T et al . Final results of the 94–01 French head and neck oncology and radiotherapy group randomized trial comparing radiotherapy alone with concomitant radiochemotherapy in advanced-stage oropharynx carcinoma. J Clin Oncol. 2004;22:69-76.
  • Duray A Demoulin S Hubert P Delvenne P Saussez S. . Immune suppression in head and neck cancers: A review. Clin Dev Immunol. 2010;2010:1-15.
  • Gillison ML Koch WM Capone RB Spafford M Westra WH Wu L et al . Evidence for a causal association between human papillomavirus and a subset of head and neck cancers. J Natl Cancer Inst. 2000;92:709-20.
  • Sturgis EM Cinciripini PM. . Trends in head and neck cancer incidence in relation to smoking prevalence: An emerging epidemic of human papillomavirus-associated cancers?. Cancer. 2007;110:1429-35.
  • Syrjänen S. . The role of human papillomavirus infection in head and neck cancers. Ann Oncol. 2010;21:243-5.
  • Dahlstrand H Näsman A Romanitan M Lindquist D Ramqvist T Dalianis T. . Human papillomavirus accounts both for increased incidence and better prognosis in tonsillar cancer. Anticancer Res. 2008;28:1133-8.
  • Rosenquist K Wennerberg J Annertz K Schildt EB Hansson BG Bladström A et al . Recurrence in patients with oral and oropharyngeal squamous cell carcinoma: Human papillomavirus and other risk factors. Acta Otolaryngol. 2007;127:980-7.
  • Duray A Descamps G Arafa M Decaestecker C Remmelink M Sirtaine N et al . High incidence of high-risk HPV in benign and malignant lesions of the larynx. Int J Oncol. 2011;39:51-9.
  • Lindel K Beer KT Laissue J Greiner RH Aebersold DM. . Human papillomavirus positive squamous cell carcinoma of the oropharynx: A radiosensitive subgroup of head and neck carcinoma. Cancer. 2001;92:805-13.
  • Lindquist D Romanitan M Hammarstedt L Näsman A Dahlstrand H Lindholm J et al . Human papillomavirus is a favourable prognostic factor in tonsillar cancer and its oncogenic role is supported by the expression of E6 and E7. Mol Oncol. 2007;1:350-5.
  • Fakhry C Westra WH Li S Cmelak A Ridge JA Pinto H et al . Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial. J Natl Cancer Inst. 2008;100:261-9.
  • Koskinen WJ Chen RW Leivo I Mäkitie A Bäck L Kontio R et al . Prevalence and physical status of human papillomavirus in squamous cell carcinomas of the head and neck. Int J Cancer. 2003;107:401-6.
  • Ragin CC Modugno F Gollin SM. . The epidemiology and risk factors of head and neck cancer: A focus on human papillomavirus. J Dent Res. 2007;86:104-14.
  • Morshed K. . Association between human papillomavirus infection and laryngeal squamous cell carcinoma. J Med Virol. 2010;82:1017-23.
  • Clayman GL Stewart MG Weber RS el-Naggar AK Grimm EA. . Human papillomavirus in laryngeal and hypopharyngeal carcinomas. Relationship to survival. Arch Otolaryngol Head Neck Surg. 1994;120:743-8.
  • Hansson BG Rosenquist K Antonsson A Wennerberg J Schildt EB Bladström A et al . Strong association between infection with human papillomavirus and oral and oropharyngeal squamous cell carcinoma: A population-based case-control study in southern Sweden. Acta Otolaryngol. 2005;125:1137-44.
  • Duray A Descamps G Decaestecker C Remmelink M Sirtaine N Lechien J et al . Human papillomavirus DNA strongly correlates with a poorer prognosis in oral cavity carcinoma. Laryngoscope. 2012;122:1558-65.
  • Schwartz SR Yueh B McDougall JK Daling JR Schwartz SM. . Human papillomavirus infection and survival in oral squamous cell cancer: A population based study. Otolaryngol Head Neck Surg. 2001;125:1-9.
  • Ritchie JM Smith EM Summersgill KF Hoffman HT Wang D Klussmann JP et al . Human papillomavirus infection as a prognostic factor in carcinomas of the oral cavity and oropharynx. Int J Cancer. 2003;104:336-44.
  • Reimers N Kasper HU Weissenborn SJ Stützer H Preuss SF Hoffmann TK et al . Combined analysis of HPV-DNA, p16 and EGFR expression to predict prognosis in oropharyngeal cancer. Int J Cancer. 2007;120:1731-8.
  • Kumar B Cordell KG Lee JS Worden FP Prince ME Tran HH et al . EGFR, p16, HPV Titer, Bcl-xL and p53, sex, and smoking as indicators of response to therapy and survival in oropharyngeal cancer. J Clin Oncol. 2008;26:3128-37.
  • Hennessey PT Westra WH Califano JA. . Human papillomavirus and head and neck squamous cell carcinoma: Recent evidence and clinical implications. J Dent Res. 2009;88:300-6.
  • Ringström E Peters E Hasegawa M Posner M Liu M Kelsey KT. . Human papillomavirus type 16 and squamous cell carcinoma of the head and neck. Clin Cancer Res. 2002;8:3187-92.
  • Sedaghat AR Zhang Z Begum S Palermo R Best S Ulmer KM et al . Prognostic significance of human papillomavirus in oropharyngeal squamous cell carcinomas. Laryngoscope. 2009;119:1542-49.
  • Ang KK Harris J Wheeler R Weber R Rosenthal DI Nguyen-Tân PF et al . Human papillomavirus and survival of patients with oropharyngeal cancer. N Engl J Med. 2010;363:24-35.
  • Ragin CC Taioli E. . Survival of squamous cell carcinoma of the head and neck in relation to human papillomavirus infection: Review and meta-analysis. Int J Cancer. 2007;121:1813-20.
  • Isayeva T Li Y Maswahu D Brandwein-Gensler M. . Human papillomavirus in non-oropharyngeal head and neck cancers: A systematic literature review. Head Neck Pathol. 2012;6:104-20.
  • Bose P Brockton NT Dort JC. . Head and neck cancer: From anatomy to biology. Int J Cancer. 2013;133:2013-23.
  • Bishop JA Westra WH. . Human papillomavirus-related small cell carcinoma of the oropharynx. Am J Surg Pathol. 2011;35:1679-84.
  • Kraft S Faquin WC Krane JF. . HPV-associated neuroendocrine carcinoma of the oropharynx: A rare new entity with potentially aggressive clinical behavior. Am J Surg Pathol. 2012;36:321-30.
  • Ernoux-Neufcoeur P Arafa M Decaestecker C Duray A Remmelink M Leroy X et al . Combined analysis of HPV DNA, p16, p21 and p53 to predict prognosis in patients with stage IV hypopharyngeal carcinoma. J Cancer Res Clin Oncol. 2011;137:173-81.
  • Kreimer AR Alberg AJ Daniel R Gravitt PE Viscidi R Garrett ES et al . Oral human papillomavirus infection in adults is associated with sexual behavior and HIV serostatus. J Infect Dis. 2004;189:686-98.
  • Moscicki AB Hills N Shiboski S Powell K Jay N Hanson E et al . Risks for incident human papillomavirus infection and low-grade squamous intraepithelial lesion development in young females. JAMA. 2001;285:2995-3002.
  • Tung YC Lin KH Chu PY Hsu CC Kuo WR. . Detection of human papilloma virus and Epstein-Barr virus DNA in nasopharyngeal carcinoma by polymerase chain reaction. Kaohsiung J Med Sci. 1999;15:256-62.
  • Stanley MA. . Immune responses to human papillomavirus. Vaccine. 2006;24:16-22.
  • Stanley MA. . Immune responses to human papillomaviruses. Indian J Med Res. 2009;130:266-76.
  • Kanodia S Fahey LM Kast WM. . Mechanisms used by human papillomaviruses to escape the host immune response. Curr Cancer Drug Targets. 2007;7:79-89.
  • Herman L Hubert P Herfs M Kustermans G Henrotin Y Bousarghin L et al . The L1 major capsid protein of HPV16 differentially modulates APC trafficking according to the vaccination or natural infection context. Eur J Immunol. 2010;40:3075-84.
  • Fahey LM Raff AB Da Silva DM Kast WM. . A major role for the minor capsid protein of human papillomavirus type 16 in immune escape. J Immunol. 2009;183:6151-6.
  • Iijima N Goodwin EC Dimaio D Iwasaki A. . High-risk human papillomavirus E6 inhibits monocyte differentiation to Langerhans cells. Virology. 2013;444:257-62.
  • Hubert P Caberg JH Gilles C Bousarghin L Franzen-Detrooz E Boniver J et al . E-cadherin-dependent adhesion of dendritic and Langerhans cells to keratinocytes is defective in cervical human papillomavirus-associated (pre)neoplastic lesions. J Pathol. 2005;206:346-55.
  • Venuti A Paolini F Nasir L Corteggio A Roperto S Campo MS et al . Papillomavirus E5: The smallest oncoprotein with many functions. Mol Cancer. 2011;10:1-18.
  • Caberg JH Hubert P Herman L Herfs M Roncarati P Boniver J et al . Increased migration of Langerhans cells in response to HPV16 E6 and E7 oncogene silencing: Role of CCL20. Cancer Immunol Immunother. 2009;58:39-47.
  • O'Donovan A Wood RD. . Identical defects in DNA repair in xeroderma pigmentosum group G and rodent ERCC group 5. Nature. 1993;363:185-8.
  • Scherly D Nouspikel T Corlet J Ucla C Bairoch A Clarkson SG. . Complementation of the DNA repair defect in xeroderma pigmentosum group G cells by a human cDNA related to yeast RAD2. Nature. 1993;363:182-5.
  • Albers A Abe K Hunt J Wang J Lopez-Albaitero A Schaefer C et al . Antitumor activity of human papillomavirus type 16 E7-specific T cells against virally infected squamous cell carcinoma of the head and neck. Cancer Res. 2005;65:11146-55.
  • Hoffmann TK Arsov C Schirlau K Bas M Friebe-Hoffmann U Klussmann JP et al . T cells specific for HPV16 E7 epitopes in patients with squamous cell carcinoma of the oropharynx. Int J Cancer. 2006;118:1984-91.
  • Heusinkveld M Goedemans R Briet RJ Gelderblom H Nortier JW Gorter A et al . Systemic and local human papillomavirus 16-specific T-cell immunity in patients with head and neck cancer. Int J Cancer. 2012;131:74-85.
  • Wansom D Light E Worden F Prince M Urba S Chepeha DB et al . Correlation of cellular immunity with human papillomavirus 16 status and outcome in patients with advanced oropharyngeal cancer. Arch Otolaryngol Head Neck Surg. 2010;136:1267-73.
  • Pereira KM Soares RC Oliveira MC Pinto LP Costa Ade L. . Immunohistochemical staining of Langerhans cells in HPV-positive and HPV-negative cases of oral squamous cells carcinoma. J Appl Oral Sci. 2011;19:378-83.
  • Näsman A Romanitan M Nordfors C Grün N Johansson H Hammarstedt L et al . Tumor infiltrating CD8+ and Foxp3+ lymphocytes correlate to clinical outcome and human papillomavirus (HPV) status in tonsillar cancer. PLoS One. 2012;7:1-8.
  • Jung AC Guihard S Krugell S Ledrappier S Brochot A Dalstein V et al . CD8-alpha T-cell infiltration in human papillomavirus-related oropharyngeal carcinoma correlates with improved patient prognosis. Int J Cancer. 2013;132:26-36.
  • Wansom D Light E Thomas D Worden F Prince M Urba S et al . Infiltrating lymphocytes and human papillomavirus-16–associated oropharyngeal cancer. Laryngoscope. 2012;122:121-7.
  • Williams R Lee DW Elzey BD Anderson ME Hostager BS Lee JH. . Preclinical models of HPV+ and HPV− HNSCC in mice: An immune clearance of HPV+ HNSCC. Head Neck. 2009;31:911-8.
  • Giskes K Kunst AE Benach J Borrell C Costa G Dahl E et al . Trends in smoking behaviour between 1985 and 2000 in nine European countries by education. J Epidemiol Community Health. 2005;59:395-401.
  • Smith EM Wang D Kim Y Rubenstein LM Lee JH Haugen TH et al . P16INK4a expression, human papillomavirus, and survival in head and neck cancer. Oral Oncol. 2008;44:133-42.
  • Weinberger PM Yu Z Haffty BG Kowalski D Harigopal M Brandsma J et al . Molecular classification identifies a subset of human papillomavirus associated oropharyngeal cancers with favorable prognosis. J Clin Oncol. 2006;24:736-47.
  • Weinberger PM Yu Z Kountourakis P Sasaki C Haffty BG Kowalski D et al . Defining molecular phenotypes of human papillomavirus associated oropharyngeal squamous cell carcinoma: validation of three-class hypothesis. Otolaryngol Head Neck Surg. 2009;141:382-9.
  • Smith EM Wang D Rubenstein LM Morris WA Turek LP Haugen TH. . Association between p53 and human papillomavirus in head and neck cancer survival. Cancer Epidemiol Biomarkers Prev. 2008;17:421-7.
  • Byrd JK Wilhoit CS Fordham MT Reeves TD McRackan TR Nguyen SA et al . Predicting HPV status in head and neck cancer: the predictive value of sociodemographic and disease characteristics. Arch Otolaryngol Head Neck Surg. 2012;138:1155-59.
  • D'Souza G Zhang HH D'Souza WD Meyer RR Gillison ML. . Moderate predictive value of demographic and behavioral characteristics for a diagnosis of HPV16-positive and HPV-16negative head and neck cancer. Oral Oncol. 2010;46:100-4.
  • Maxwell JH Kumar B Feng FY Worden FP Lee JS Eisbruch A et al . Tobacco use in human papillomavirus-positive advanced oropharynx cancer patients related to increased risk of distant metastases and tumor recurrence. Clin Cancer Res. 2010;16:1226-35.
  • Hafkamp HC Manni JJ Haesevoets A Voogd AC Schepers M Bot FJ et al . Marked differences in survival rate between smokers and nonsmokers with HPV 16-associated tonsillar carcinomas. Int J Cancer. 2008;122:2656-64.
  • Tribius S Hoffmann AS Bastrop S Görögh T Haag J Röcken C et al . HPV status in patients with head and neck of carcinoma of unknown primary site: HPV, tobacco smoking, and outcome. Oral Oncol. 2012;48:1178-84.
  • Lin BM Wang H D'Souza G Zhang Z Fakhry C Joseph AW et al . Long-term prognosis and risk factors among patients with HPV-associated oropharyngeal squamous cell carcinoma. Cancer. 2013;119:3462-71.
  • Gillison ML Zhang Q Jordan R Xiao W Westra WH Trotti A et al . Tobacco smoking and increased risk of death and progression for patients with p16-positive and p16-negative oropharyngeal cancer. J Clin Oncol. 2012;30:2102-11.
  • Schwartz SM Daling JR Doody DR Wipf GC Carter JJ Madeleine MM et al . Oral cancer risk in relation to sexual history and evidence of human papillomavirus infection. J Natl Cancer Inst. 1998;90:1626-36.
  • Herrero R Castellsagué X Pawlita M Lissowska J Kee F Balaram P et al . Human papillomavirus and oral cancer: The International Agency for Research on Cancer multicenter study. J Natl Cancer Inst. 2003;95:1772-83.
  • Smith EM Ritchie JM Summersgill KF Klussmann JP Lee JH Wang D et al . Age, sexual behavior and human papillomavirus infection in oral cavity and oropharyngeal cancers. Int J Cancer. 2004;108:766-72.
  • Smith EM Rubenstein LM Haugen TH Hamsikova E Turek LP. . Tobacco and alcohol use increases the risk of both HPV-associated and HPV-independent head and neck cancers. Cancer Causes Control. 2010;21:1369-78.
  • Snijders PJ Scholes AG Hart CA Jones AS Vaughan ED Woolgar JA et al . Prevalence of mucosotropic human papillomaviruses in squamous-cell carcinoma of the head and neck. Int J Cancer. 1996;66:464-69.
  • Paz IB Cook N Odom-Maryon T Xie Y Wilczynski SP. . Human papillomavirus (HPV) in head and neck cancer. An association of HPV 16 with squamous cell carcinoma of Waldeyer's tonsillar ring. Cancer. 1997;79:595-604.
  • D'Souza G Kreimer AR Viscidi R Pawlita M Fakhry C Koch WM et al . Case-control study of human papillomavirus and oropharyngeal cancer. N Engl J Med. 2007;356:1944-56.
  • Gillison ML D'Souza G Westra W Sugar E Xiao W Begum S et al . Distinct risk factor profiles for human papillomavirus type 16-positive and human papillomavirus type 16-negative head and neck cancers. J Natl Cancer Inst. 2008;100:407-20.
  • Hong AM Martin A Chatfield M Jones D Zhang M Armstrong B et al . Human papillomavirus, smoking status and outcomes in tonsillar squamous cell carcinoma. Int J Cancer. 2013;132:2748-54.
  • Arnson Y Shoenfeld Y Amital H. . Effects of tobacco smoke on immunity, inflammation and autoimmunity. J Autoimmun. 2010;34:258-65.
  • Mehta H Nazzal K Sadikot RT. . Cigarette smoking and innate immunity. Inflamm Res. 2008;57:497-503.
  • Palmer RM Wilson RF Hasan AS Scott DA. . Mechanisms of action of environmental factors – tobacco smoking. J Clin Periodontol. 2005;32:180-95.
  • Lee J Taneja V Vassalo R. . Cigarette smoking and inflammation: Cellular and molecular mechanisms. JDR. 2012;91:142-9.