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Original Research Articles

Comparative analysis of discrete exosome fractions obtained by differential centrifugation

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Article: 25011 | Received 23 May 2014, Accepted 26 Sep 2014, Published online: 06 Nov 2014

References

  • Cocucci E, Racchetti G, Meldolesi J. Shedding microvesicles: artefacts no more. Trends Cell Biol. 2009; 19: 43–51.
  • Thery C, Ostrowski M, Segura E. Membrane vesicles as conveyors of immune responses. Nat Rev Immunol. 2009; 9: 581–93. [PubMed Abstract].
  • Simpson RJ, Lim JW, Moritz RL, Mathivanan S. Exosomes: proteomic insights and diagnostic potential. Expert Rev Proteomics. 2009; 6: 267–83. [PubMed Abstract].
  • Vlassov AV, Magdaleno S, Setterquist R, Conrad R. Exosomes: current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials. Biochim Biophys Acta. 2012; 1820: 940–8. [PubMed Abstract].
  • Ostenfeld MS. Cellular disposal of miR23b by RAB27-dependent exosome release is linked to acquisition of metastatic properties. Cancer Res. 2014; 74: 5758–71. [PubMed Abstract].
  • Simons M, Raposo G. Exosomes – vesicular carriers for intercellular communication. Curr Opin Cell Biol. 2009; 21: 575–81. [PubMed Abstract].
  • Skog J, Wurdinger T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M et al. Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat Cell Biol. 2008; 10: 1470–6. [PubMed Abstract] [PubMed CentralFull Text].
  • Lee TH, D'Asti E, Magnus N, Al-Nedawi K, Meehan B, Rak J. Microvesicles as mediators of intercellular communication in cancer – the emerging science of cellular ‘debris’. Semin Immunopathol. 2011; 33: 455–67. [PubMed Abstract].
  • Witwer KW, Buzas EI, Bemis LT, Bora A, Lasser C, Lotvall J. Standardization of sample collection, isolation and analysis methods in extracellular vesicle research. J Extracell Vesicles. 2013; 2 doi: http://dx.doi.org/10.3402/jev.v2i0.20360 [PubMed CentralFull Text].
  • Thery C, Amigorena S, Raposo G, Clayton A. Isolation and characterization of exosomes from cell culture supernatants and biological fluids. Curr Protoc Cell Biol. 2006. Chapter 3:Unit 3.22.
  • Raposo G, Stoorvogel W. Extracellular vesicles: exosomes, microvesicles, and friends. J Cell Biol. 2013; 200: 373–83. [PubMed Abstract] [PubMed CentralFull Text].
  • Abas L, Luschnig C. Maximum yields of microsomal-type membranes from small amounts of plant material without requiring ultracentrifugation. Anal Biochem. 2010; 401: 217–27. [PubMed Abstract] [PubMed CentralFull Text].
  • Lavoie C, Lanoix J, Kan FW, Paiement J. Cell-free assembly of rough and smooth endoplasmic reticulum. J Cell Sci. 1996; 109: 1415–25. [PubMed Abstract].
  • Dragovic RA, Gardiner C, Brooks AS, Tannetta DS, Ferguson DJ, Hole P et al. Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis. Nanomedicine. 2011; 7: 780–8. [PubMed Abstract] [PubMed CentralFull Text].
  • Gercel-Taylor C, Atay S, Tullis RH, Kesimer M, Taylor DD. Nanoparticle analysis of circulating cell-derived vesicles in ovarian cancer patients. Anal Biochem. 2012; 428: 44–53. [PubMed Abstract].
  • Gardiner C, Ferreira YJ, Dragovic RA, Redman CW, Sargent IL. Extracellular vesicle sizing and enumeration by nanoparticle tracking analysis. J Extracell Vesicles. 2013; 2 19671, doi: http://dx.doi.org/10.3402/jev.v2i0.19671.
  • Gould SJ, Raposo G. As we wait: coping with an imperfect nomenclature for extracellular vesicles. J Extracell Vesicles. 2013; 2 20389, doi: http://dx.doi.org/10.3402/jev.v2i0.20389.
  • Lamparski HG, Metha-Damani A, Yao JY, Patel S, Hsu DH, Ruegg C et al. Production and characterization of clinical grade exosomes derived from dendritic cells. J Immunol Methods. 2002; 270: 211–26. [PubMed Abstract].
  • Keller S, Ridinger J, Rupp AK, Janssen JW, Altevogt P. Body fluid derived exosomes as a novel template for clinical diagnostics. J Transl Med. 2011; 9: 86. [PubMed Abstract] [PubMed CentralFull Text].
  • Nolte-'t Hoen EN, van der Vlist EJ, Aalberts M, Mertens HC, Bosch BJ, Bartelink W et al. Quantitative and qualitative flow cytometric analysis of nanosized cell-derived membrane vesicles. Nanomedicine. 2012; 8: 712–20. [PubMed Abstract].
  • Baietti MF, Zhang Z, Mortier E, Melchior A, Degeest G, Geeraerts A et al. Syndecan-syntenin-ALIX regulates the biogenesis of exosomes. Nat Cell Biol. 2012; 14: 677–85. [PubMed Abstract].
  • Cantin R, Diou J, Belanger D, Tremblay AM, Gilbert C. Discrimination between exosomes and HIV-1: purification of both vesicles from cell-free supernatants. J Immunol Methods. 2008; 338: 21–30. [PubMed Abstract].
  • Yuana Y, Levels J, Grootemaat A, Sturk A, Nieuwland R. Co-isolation of extracellular vesicles and high-density lipoproteins using density gradient ultracentrifugation. J Extracell Vesicles. 2014; 3 23262, doi: http://dx.doi.org/10.3402/jev.v3.23262.
  • Mitchell JP, Court J, Mason MD, Tabi Z, Clayton A. Increased exosome production from tumour cell cultures using the Integra CELLine Culture System. J Immunol Methods. 2008; 335: 98–105. [PubMed Abstract].
  • Ostenfeld MS, Bramsen JB, Lamy P, Villadsen SB, Fristrup N, Sorensen KD et al. miR-145 induces caspase-dependent and -independent cell death in urothelial cancer cell lines with targeting of an expression signature present in Ta bladder tumors. Oncogene. 2010; 29: 1073–84. [PubMed Abstract].
  • Nicholson BE, Frierson HF, Conaway MR, Seraj JM, Harding MA, Hampton GM et al. Profiling the evolution of human metastatic bladder cancer. Cancer Res. 2004; 64: 7813–21. [PubMed Abstract].
  • Quah BJ, O'Neill HC. Mycoplasma contaminants present in exosome preparations induce polyclonal B cell responses. J Leukoc Biol. 2007; 82: 1070–82. [PubMed Abstract].
  • Yang C, Chalasani G, Ng YH, Robbins PD. Exosomes released from Mycoplasma infected tumor cells activate inhibitory B cells. PLoS One. 2012; 7: e36138. [PubMed Abstract] [PubMed CentralFull Text].
  • Webber J, Clayton A. How pure are your vesicles?. J Extracell Vesicles. 2013; 2 19861, doi: http://dx.doi.org/10.3402/jev.v2i0.19861.
  • Bobrie A, Colombo M, Krumeich S, Raposo G, Thery C. Diverse subpopulations of vesicles secreted by different intracellular mechanisms are present in exosome preparations obtained by differential ultracentrifugation. J Extracell Vesicles. 2012; 1 18397, doi: http://dx.doi.org/10.3402/jev.v1i0.18397 [PubMed CentralFull Text].
  • Jeppesen DK, Nawrocki A, Jensen SG, Thorsen K, Whitehead B, Howard KA et al. Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential expression of EMT factors. Proteomics. 2014; 14: 699–712. [PubMed Abstract].
  • Khatua AK, Taylor HE, Hildreth JE, Popik W. Exosomes packaging APOBEC3G confer human immunodeficiency virus resistance to recipient cells. J Virol. 2009; 83: 512–21. [PubMed Abstract] [PubMed CentralFull Text].
  • Perez-Hernandez D, Gutierrez-Vazquez C, Jorge I, Lopez-Martin S, Ursa A, Sanchez-Madrid F et al. The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. J Biol Chem. 2013; 288: 11649–61. [PubMed Abstract] [PubMed CentralFull Text].
  • Bobrie A, Thery C. Exosomes and communication between tumours and the immune system: are all exosomes equal?. Biochem Soc Trans. 2013; 41: 263–7. [PubMed Abstract].
  • Camussi G, Deregibus MC, Tetta C. Tumor-derived microvesicles and the cancer microenvironment. Curr Mol Med. 2013; 13: 58–67. [PubMed Abstract].
  • Kucharzewska P, Belting M. Emerging roles of extracellular vesicles in the adaptive response of tumour cells to microenvironmental stress. J Extracell Vesicles. 2013; 2 20304, doi: http://dx.doi.org/10.3402/jev.v2i0.20304.
  • Kosaka N, Takeshita F, Yoshioka Y, Hagiwara K, Katsuda T, Ono M et al. Exosomal tumor-suppressive microRNAs as novel cancer therapy: “exocure” is another choice for cancer treatment. Adv Drug Deliv Rev. 2013; 65: 376–82. [PubMed Abstract].
  • EL Andaloussi S, Mager I, Breakefield XO, Wood MJ. Extracellular vesicles: biology and emerging therapeutic opportunities. Nat Reviews Drug Dis. 2013; 12: 347–57.
  • Gyorgy B, Modos K, Pallinger E, Paloczi K, Pasztoi M, Misjak P et al. Detection and isolation of cell-derived microparticles are compromised by protein complexes resulting from shared biophysical parameters. Blood. 2011; 117: e39–48. [PubMed Abstract].
  • Saunderson SC, Schuberth PC, Dunn AC, Miller L, Hock BD, MacKay PA et al. Induction of exosome release in primary B cells stimulated via CD40 and the IL-4 receptor. J Immunol. 2008; 180: 8146–52. [PubMed Abstract].
  • Colombo M, Moita C, van Niel G, Kowal J, Vigneron J, Benaroch P et al. Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles. J Cell Sci. 2013; 126: 5553–65. [PubMed Abstract].
  • Yoshioka Y, Konishi Y, Kosaka N, Katsuda T, Kato T, Ochiya T. Comparative marker analysis of extracellular vesicles in different human cancer types. J Extracell Vesicles. 2013; 2 20424, doi: http://dx.doi.org/10.3402/jev.v2i0.20424 [PubMed CentralFull Text].
  • Cvjetkovic A, Lotvall J, Lasser C. The influence of rotor type and centrifugation time on the yield and purity of extracellular vesicles. J Extracell Vesicles. 2014; 3 23111, doi: http://dx.doi.org/10.3402/jev.v3.23111 [PubMed CentralFull Text].