56
Views
12
CrossRef citations to date
0
Altmetric
Original Articles

Recognizing atypical manifestations of GERD

Asthma, chest pain, and otolaryngologic disorders may be due to reflux

, MD & , MD, PhD
Pages 53-66 | Published online: 30 Jun 2015

References

  • Richter JE. Dysphagia, odynophagia, heartburn, and other esophageal symptoms. In: Feldman M, Sleisenger MH, Scharschmidt BF, eds. Gastrointestinal and liver disease: pathophysiology, diagnosis, management. 6th ed. Philadelphia: Saunders, 1998: 97–105
  • Nebel OT, Fornes MF, Castell DO. Symptomatic gastroesophageal reflux: incidence and precipitating factors. Am J Dig Dis 1976; 21(11): 953–6
  • McFadden ER Jr. Asthma. In: Isselbacher KJ, Braunwald E, et al, eds. Harrison's principles of internal medicine. 13th ed. New York: McGraw-Hill, 1994: 1167–72
  • Harding SM, Richter JE. Gastroesophageal reflux disease and asthma. Seminar Gastrointest Dis 1992; 3(3): 139–50
  • Schnatz PF, Castell JA, Castell DO. Pulmonary symptoms associated with gastroesophageal reflux: use of ambulatory pH monitoring to diagnose and to direct therapy. Am J Gastroenterol 1996; 91(9):1715–8
  • Sontag SJ, O'Connell S, Khandelwal S, et al. Most asthmatics have gastroesophageal reflux with or without bronchodilator therapy. Gastroenterology 1990; 99(3): 613–20
  • Wesseling G, Brummer RJ, Wouters EF, et al. Gastric asthma? No change in respiratory impedance during intraesophageal acidification in adult asthmatics. Chest 1993; 104(6):1733–6
  • Tuchman DN, Boyle JT, Pack Al, et al. Comparison of airway responses following tracheal or esophageal acidification in the cat. Gastroenterology 1984; 87(4):872–81
  • Kjellen G. Association of esophageal dysfunction and asthma: improvement in asthma with conservative management of esophageal signs. Int Med Specialist 1982; 3:54–62
  • Sontag SJ, Schnell TG, Miller TQ, et al. Prevalence of oesophagitis in asthmatics. Gut 1992;33(7): 872–6
  • Ekstrom T, Lindgren BR, Tibbling L. Effects of ranitidine treatment on patients with asthma and a history of gastroesophageal reflux: a double blind crossover study. Thorax 1989;44(1):19–23
  • Larrain A, Carrasco E, Galleguillos F, et al. Medical and surgical treatment of nonallergic asthma associated with gastroesophageal reflux. Chest 1991;99(6):1330–5
  • Harding SM, Richter JE, Guzzo MR, et al. Asthma and gastroesophageal reflux: acid suppressive therapy improves asthma outcome. Am J Med 1996;100(4):395–405
  • Tucci F, Resti M, Fontana R, et al. Gastroesophageal reflux and bronchial asthma: prevalence and effect of cisapride therapy. J Pediatr Gastroenterol Nutr 1993;17(3):265–70
  • Rao SS. Esophageal (noncardiac) chest pain: visceral hyperalgesia, motor.disorder, or reflux disease? In: Gebhart GF, ed. Visceral pain: progress in pain research and management. Vol 5. Seattle: I ASP Press, 1995: 351–71
  • Rao SS, Gregersen H, Hayek B, et al. Unexplained chest pain: the hypersensitive, hyperreactive, and poorly compliant esophagus. Ann Intern Med 1996; 124(11): 950–8
  • Schofield PM, Bennett DH, Whorwell PJ, et al. Exertional gastro-oesophageal reflux: a mechanism for symptoms in patients with angina pectoris and normal coronary angiograms. Br Med J (Clin Res Ed) 1987; 294(6585): 1459–61
  • Hewson EG, Sinclair JW, Dalton CB, et al. Twenty-four-hour esophageal pH monitoring: the most useful test for evaluating noncardiac chest pain. Am J Med 1991; 90(5): 576–83
  • Ward BW, Wu WC, Richter JE, et al. Long-term follow-up of symptomatic status of patients with noncardiac chest pain: is diagnosis of esophageal etiology helpful? Am J Gastroenterol 1987; 82(3): 215–8
  • Richter JE, Hewson EG, Sinclair JW, et al. Acid perfusion test and 24-hour esophageal pH monitoring with symptom index: comparison of tests for esophageal acid sensitivity. Dig Dis Sci 1991; 36(5): 565–71
  • Richter JE, Schan C, Burgard S, et al. Placebo controlled trial of omeprazole in the treatment of acid-related non-cardiac chest pain (NCCP). (Abstr) Am J Gastroenterol 1992; 87: 1255
  • DeMeester TR, O'Sullivan GC, Bermudez G, et al. Esophageal function in patients with angina-type chest pain and normal coronary angiograms. Ann Surg 1982; 196(4): 488–98
  • Stahl WG, Beton RR, Johnson CS, et al. High-dose ranitidine in the treatment of patients with non-cardiac chest pain and evidence of gastroesophageal reflux. (Abstr) Gastroenterology 1992; 102(4 Pt 2): A168
  • Koufman JA. The otolaryngologic manifestations of gastroesophageal reflux disease (GERD): a clinical investigation of 225 patients using ambulatory 24-hour pH monitoring and an experimental investigation of the role of acid and pepsin in the development of laryngeal injury. Laryngoscope 1991; 101 (4 Pt 2 Suppl 53): 1–78
  • Koufman JA, Wiener GJ, Wu WC, et al. Reflux laryngitis and its sequelae: the diagnostic role of ambulatory 24-hour pH monitoring. J Voice 1988; 2(1): 78–89
  • Kahrilas PJ, Dodds WJ, Dent J, et al. Effect of sleep, spontaneous gastroesophageal reflux, and a meal on upper esophageal sphincter pressure in normal human volunteers. Gastroenterology 1987; 92(2): 466–71
  • de Caestecker J. Medical therapy for supraesophageal complications of gastroesophageal reflux. Am J Med 1997; 103(5A): 138S-43S

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.