References
- Korfmacher WA . Principles and applications of LC–MS in new drug discovery. Drug Discov. Today10 (20), 1357–1367 (2005).
- Xian F , HendricksonCL, MarshallAG. High resolution mass spectrometry. Anal. Chem. 84 (2), 708–179 (2012).
- Ramanathan R , KorfmacherW. The emergence of high-resolution MS as the premier analytical tool in the pharmaceutical bioanalysis arena. Bioanalysis4 (5), 467–469 (2012).
- Ramanathan R , JemalM, RamagiriSet al. It is time for a paradigm shift in drug discovery bioanalysis: from SRM to HRMS. J. Mass Spectrom. 46 (6), 595–601 (2011).
- Korfmacher W . High-resolution mass spectrometry will dramatically change our drug-discovery bioanalysis procedures. Bioanalysis3 (11), 1169–1171 (2011).
- Ramanathan DM . Looking beyond the SRM to high-resolution MS paradigm shift for DMPK studies. Bioanalysis5 (10), 1141–1143 (2013).
- Huang MQ , LinZJ, WengW. Applications of high-resolution MS in bioanalysis. Bioanalysis5 (10), 1269–1176 (2013).
- Fung EN , JemalM, AubryAF. High-resolution MS in regulated bioanalysis: where are we now and where do we go from here?Bioanalysis5 (10), 1277–1284 (2013).
- King L , KotianA, JairajM. Introduction of a routine quan/qual approach into research DMPK: experiences and evolving strategies. Bioanalysis6 (24), 3337–3348 (2014).
- Zelesky V , SchneiderR, JaniszewskiJ, ZamoraI, FergusonJ, TroutmanM. Software automation tools for increased throughput metabolic soft-spot identification in early drug discovery. Bioanalysis5 (10), 1165–1179 (2013).
- Ma S , ChowdhurySK. Data acquisition and data mining techniques for metabolite identification using LC coupled to high-resolution MS. Bioanalysis5 (10), 1285–1297 (2013).
- Grondin A , PillonA, VandenbergheI, GuilbaudN, KruczynskiA, GomesB. Discovery bioanalysis and in vivo pharmacology as an integrated process: a case study in oncology drug discovery. Bioanalysis8 (14), 1481–1498 (2016).
- Wei H , TymiakAA, ChenG. High-resolution MS for structural characterization of protein therapeutics: advances and future directions. Bioanalysis5 (10), 1299–1313 (2013).
- Morin LP , MessJN, GarofoloF. Large-molecule quantification: sensitivity and selectivity head-to-head comparison of triple quadrupole with Q-TOF. Bioanalysis5 (10), 1181–1193 (2013).
- Dillen L , CoolsW, VereykenLet al. Comparison of triple quadrupole and high-resolution TOF-MS for quantification of peptides. Bioanalysis4 (5), 565–579 (2012).
- Henry H , SobhiHR, ScheibnerO, BromirskiM, NimkarSB, RochatB. Comparison between a high-resolution single-stage Orbitrap and a triple quadrupole mass spectrometer for quantitative analyses of drugs. Rapid Commun. Mass Spectrom. 26 (5), 499–509 (2012).
- Ramanathan R , KorfmacherW. HRMS or HRAMS. Bioanalysis8 (16), 1639–1640 (2016).
- Rago B , NegahbanA. Outsource-ability of HRMS-based DMPK Assays. Bioanalysis8 (16), 1641–1644 (2016).
- Aratyn-Schaus Y , RamanathanR. Advances in high resolution mass spectrometry and hepatocyte models solve a long-standing metabolism challenge: the loratadine story. Bioanalysis8 (16), 1645–1662 (2016).
- Sturm RM . High resolution accurate mass spectrometry for quantitative regulated bioanalysis: how, when, and why to implement. Bioanalysis8 (16), 1709–1721 (2016).
- Grafmuller L , WeiC, RamanathanR, BarlettaF, SteenwykR, TweedJ. Unconjugated payload quantification and DAR characterization of antibody-drug conjugates using high resolution mass spectrometry (HRMS). Bioanalysis8 (16), 1663–1678 (2016).
- Weng N . A workflow for absolute quantitation of large therapeutic proteins in biological samples at intact level using LC-HRMS. Bioanalysis8 (16), 1679–1691 (2016).
- Chowdhury S . Development of an accelerated background subtraction algorithm for processing high resolution mass spectrometry data. Bioanalysis8 (16), 1693–1707 (2016).
- Shou WZ . Recent developments in software and automation tools for high-throughput discovery in vitro ADME assays based on HRMS. Bioanalysis8 (16), 1723–1733 (2016).
- Hopfgartner G . SWATH acquisition mode for drug metabolism and metabolomics investigations. Bioanalysis8 (16), 1735–1750 (2016).