Bioanalysis, Volume 8, Issue 16 (2016)

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Bioanalysis, Volume 8, Issue 16 (2016)

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Special Focus Issue: HRMS in DMPK – Foreword

Introduction
HRMS in DMPK
Walter Korfmacher & Ragu Ramanathan
Pages: 1635-1637
Published online: 03 Aug 2016
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Opinion

Editorial
HRMS or Hrams?
Ragu Ramanathan & Walter Korfmacher
Pages: 1639-1640
Published online: 20 Jul 2016
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Commentary

Editorial
Outsource-Ability of High-Resolution MS-Based DMPK Assays
Brian Rago & Andre Negahban
Pages: 1641-1644
Published online: 15 Jul 2016
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Preliminary Communication

Brief Report
Advances in High-Resolution MS and Hepatocyte Models Solve A Long-Standing Metabolism Challenge: The Loratadine Story
Yvonne Aratyn-Schaus & Ragu Ramanathan
Pages: 1645-1662
Published online: 27 Jul 2016
AbstractforAdvances in High-Resolution MS and Hepatocyte Models Solve A Long-Standing Metabolism Challenge: The Loratadine Story | Full Text | References | PDF (4.2 MB)
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Research Article

Article
Unconjugated Payload Quantification and Dar Characterization of Antibody–Drug Conjugates Using High-Resolution MS
Leanne Grafmuller, Cong Wei, Ragu Ramanathan, Frank Barletta, Rick Steenwyk & Joseph Tweed
Pages: 1663-1678
Published online: 20 Jul 2016
AbstractforUnconjugated Payload Quantification and Dar Characterization of Antibody–Drug Conjugates Using High-Resolution MS | Full Text | References | PDF (1.7 MB) | Supplemental
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Article
A Workflow for Absolute Quantitation of Large Therapeutic Proteins in Biological Samples at Intact Level Using LC-HRMS
Wenying Jian, Lijuan Kang, Lyle Burton & Naidong Weng
Pages: 1679-1691
Published online: 20 Jul 2016
AbstractforA Workflow for Absolute Quantitation of Large Therapeutic Proteins in Biological Samples at Intact Level Using LC-HRMS | Full Text | References | PDF (1.5 MB)
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Article
An Accelerated Background Subtraction Algorithm for Processing High-Resolution MS Data and its Application to Metabolite Identification
Venkateswaran Shekar, Abhi Shah, Mohammad Shadid, Jing-Tao Wu, Jayaprakasam Bolleddula & Swapan Chowdhury
Pages: 1693-1707
Published online: 27 Jul 2016
AbstractforAn Accelerated Background Subtraction Algorithm for Processing High-Resolution MS Data and its Application to Metabolite Identification | Full Text | References | PDF (2.4 MB) | Supplemental
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Perspective

Review Article
HRMS Using A Q-Exactive Series Mass Spectrometer for Regulated Quantitative Bioanalysis: How, When, and Why to Implement
Robert M Sturm, Barry R Jones, Daniel E Mulvana & Steve Lowes
Pages: 1709-1721
Published online: 27 Jul 2016
AbstractforHRMS Using A Q-Exactive Series Mass Spectrometer for Regulated Quantitative Bioanalysis: How, When, and Why to Implement | Full Text | References | PDF (1.5 MB)
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Review

Review Article
Recent Developments in Software Tools for High-Throughput In Vitro ADME Support with High-Resolution MS
Anthony Paiva & Wilson Z Shou
Pages: 1723-1733
Published online: 20 Jul 2016
AbstractforRecent Developments in Software Tools for High-Throughput In Vitro ADME Support with High-Resolution MS | Full Text | References | PDF (1.7 MB)
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Research Article

Article
Swath Acquisition Mode for Drug Metabolism and Metabolomics Investigations
Ron Bonner & Gérard Hopfgartner
Pages: 1735-1750
Published online: 27 Jul 2016
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