References
- Korfmacher WA . Principles and applications of LC–MS in new drug discovery. Drug Discov. Today10 (20), 1357–1367 (2005).
- Korfmacher W , CoxK, BryantMet al. HPLC-API/MS/MS: a powerful tool for integrating drug metabolism into the drug discovery process. Drug Discov. Today2 (12), 532–537 (1997).
- Jonsson O , VillarRP, NilssonLB, ErikssonM, KonigssonK. Validation of a bioanalytical method using capillary microsampling of 8 microl plasma samples: application to a toxicokinetic study in mice. Bioanalysis4 (16), 1989–1998 (2012).
- Jonsson O , Palma VillarR, NilssonLBet al. Capillary microsampling of 25 microl blood for the determination of toxicokinetic parameters in regulatory studies in animals. Bioanalysis4 (6), 661–674 (2012).
- Nilsson LB , AhnoffM, JonssonO. Capillary microsampling in the regulatory environment: validation and use of bioanalytical capillary microsampling methods. Bioanalysis5 (6), 731–738 (2013).
- Jonsson O , SteffenAC, SundquistVSet al. Capillary microsampling and analysis of 4-microl blood, plasma and serum samples to determine human alpha-synuclein elimination rate in mice. Bioanalysis5 (4), 449–462 (2013).
- Dillen L , LoomansT, Van De PerreG, VersweyveldD, WuytsK, De ZwartL. Blood microsampling using capillaries for drug-exposure determination in early preclinical studies: a beneficial strategy to reduce blood sample volumes. Bioanalysis6 (3), 293–306 (2014).
- Chapman K , ChiversS, GliddonDet al. Overcoming the barriers to the uptake of nonclinical microsampling in regulatory safety studies. Drug Discov. Today19 (5), 528–532 (2014).
- Korfmacher W , FitzgeraldM, LuoYet al. Capillary microsampling of whole blood for mouse PK studies: an easy route to serial blood sampling. Bioanalysis7 (4), 449–461 (2015).
- Rahavendran SV , VekichS, SkorHet al. Discovery pharmacokinetic studies in mice using serial microsampling, dried blood spots and microbore LC–MS/MS. Bioanalysis4 (9), 1077–1095 (2012).
- Wickremsinhe ER , AbdulBG, HuangNHet al. Dried blood spot sampling: coupling bioanalytical feasibility, blood-plasma partitioning and transferability to in vivo preclinical studies. Bioanalysis3 (14), 1635–1646 (2011).
- Denniff P , SpoonerN. The effect of hematocrit on assay bias when using DBS samples for the quantitative bioanalysis of drugs. Bioanalysis2 (8), 1385–1395 (2010).
- De Vries R , BarfieldM, Van De MerbelNet al. The effect of hematocrit on bioanalysis of DBS: results from the EBF DBS-microsampling consortium. Bioanalysis5 (17), 2147–2160 (2013).
- Denniff P , SpoonerN. Volumetric absorptive microsampling: a dried sample collection technique for quantitative bioanalysis. Anal. Chem. 86 (16), 8489–8495 (2014).
- Spooner N , DenniffP, MichielsenLet al. A device for dried blood microsampling in quantitative bioanalysis: overcoming the issues associated blood hematocrit. Bioanalysis7 (6), 653–659 (2015).
- Denniff P , ParryS, DopsonW, SpoonerN. Quantitative bioanalysis of paracetamol in rats using volumetric absorptive microsampling (VAMS). J. Pharm. Biomed. Anal. 108, 61–69 (2015).
- Diehl KH , HullR, MortonDet al. A good practice guide to the administration of substances and removal of blood, including routes and volumes. J. Appl. Toxicol. 21 (1), 15–23 (2001).
- Spreadborough MJ , DayJ, Jackson-AddieK, WilsonA. Bioanalytical implementation of plasma capillary microsampling: small hurdles, large gains. Bioanalysis5 (12), 1485–1489 (2013).
- Korfmacher W . Strategies and techniques for bioanalytical assays as part of new drug discovery. In : Using Mass Spectrometry for Drug Metabolism Studies. KorfmacherW ( Ed.). CRC Press, FL, USA1–31 (2010).
- Hui YH , HuangNH, EbbertLet al. Pharmacokinetic comparisons of tail-bleeding with cannula- or retro-orbital bleeding techniques in rats using six marketed drugs. J. Pharmacol. Toxicol. Methods56 (2), 256–264 (2007).