References
- Liu S , HouY, LiuW, LuC, WangW, SunS. Components of the calcium–calcineurin signaling pathway in fungal cells and their potential as antifungal targets. Eukaryot. Cell14 (4), 324–334 (2015).
- Martin DC , KimH, MackinNAet al. New regulators of a high affinity Ca2+ influx system revealed through a genome-wide screen in yeast. J. Biol. Chem.286 (12), 10744–10754 (2011).
- Wang H , LuG, YangBet al. Effect of CCH1 or MID1 gene disruption on drug tolerance and pathogenesis of Candida albicans. Sheng Wu Gong Cheng Xue Bao28 (6), 726–736 (2012).
- Liu S , YueL, GuW, LiX, ZhangL, SunS. Synergistic effect of fluconazole and calcium channel blockers against resistant Candida albicans. PLoS ONE11 (3), e0150859 (2016).
- Teng J , GotoR, IidaK, KojimaI, IidaH. Ion-channel blocker sensitivity of voltage-gated calcium-channel homologue Cch1 in Saccharomyces cerevisiae. Microbiology154 (Pt 12), 3775–3781 (2008).
- Juvvadi PR , LamothF, SteinbachWJ. Calcineurin as a multifunctional regulator: unraveling novel functions in fungal stress responses, hyphal growth, drug resistance, and pathogenesis. Fungal. Biol. Rev.28 (2–3), 56–69 (2014).
- Li H , ChenZ, ZhangC, GaoY, ZhangX, SunS. Resistance reversal induced by combination of fluconazole and tacrolimus in Candida glabrata. J. Med. Microbiol.64 (Pt 1), 44–52 (2015).
- Marchetti O , MoreillonP, GlauserMP, BilleJ, SanglardD. Potent synergism of the combination of fluconazole and cyclosporine in Candida albicans. Antimicrob. Agents Chemother.44 (9), 2373–2381 (2000).
- Hallstrom TC , LambertL, SchorlingS, BalziE, GoffeauA, Moye-RowleyWS. Coordinate control of sphingolipid biosynthesis and multidrug resistance in Saccharomyces cerevisiae. J. Biol. Chem.276 (26), 23674–23680 (2001).
- Mukhopadhyay K , KohliA, PrasadR. Drug susceptibilities of yeast cells are affected by membrane lipid composition. Antimicrob. Agents Chemother.46 (12), 3695–3705 (2002).
- Löffler J , EinseleH, HebartH, SchumacherU, HrastnikC, DaumG. Phospholipid and sterol analysis of plasma membranes of azole-resistant Candida albicans strains. FEMS Microbiol. Lett.185 (1), 59–63 (2000).
- Jia X , MaZ, JiaYet al. RTA2, a novel gene involved in azole resistance in Candida albicans. Biochem. Biophys. Res. Commun.373 (4), 631–636 (2008).
- Jia X , WangY, JiaYet al. RTA2 is involved in calcineurin-mediated azole resistance and sphingoid long-chain base release in Candida albicans. Cell. Mol. Life Sci.66 (1), 122–134 (2009).
- Cowen LE , SinghSD, KöhlerJRet al. Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease. Proc. Natl Acad. Sci. USA106 (8), 2818–2823 (2009).
- Heath VL , ShawSL, RoyS, CyertMS. Hph1p and Hph2p, novel components of calcineurin-mediated stress responses in Saccharomyces cerevisiae. Eukaryot. Cell3 (3), 695–704 (2004).
- Karababa M , ValentinoE, PardiniG, CosteAT, BilleJ, SanglardD. CRZ1, a target of the calcineurin pathway in Candida albicans. Mol. Microbiol.59 (5), 1429–1451 (2006).
- Cowen LE , CarpenterAE, MatangkasombutO, FinkGR, LindquistS. Genetic architecture of Hsp90-dependent drug resistance. Eukaryot. Cell5 (12), 2184–2188 (2006).
- Liu X , ZhangZ. The action target mechanism of antifungal agents research advances of novel drugs. Chin. J. Pharm. Anal.35 (2), 193–202 (2015).