References
- Alexander J , SatoskarAR, RussellDG. Leishmania species: models of intracellular parasitism.J. Cell Sci.112(18), 2993–3002 (1999).
- Bhardwaj N , RosasLE, LafuseWP, SatoskarAR. Leishmania inhibits STAT1-mediated IFN-gamma signaling in macrophages: increased tyrosine phosphorylation of dominant negative STAT1beta by Leishmania Mexicana.Int. J. Parasitol.35, 75–82 (2005).
- Nandan D , ReinerNE. Attenuation of gamma interferon-induced tyrosine phosphorylation in mononuclear phagocytes infected with Leishmania donovani: selective inhibition of signaling through Janus kinases and Stat1. Infect. Immun.63, 4495–4500 (1995).
- Ray M , GamAA, BoykinsRA, KenneyRT. Inhibition of interferon-gamma signaling by Leishmania donovani. J. Infect. Dis.181, 1121–1128 (2000).
- Blanchette J , RacetteN, FaureR, SiminovitchKA, OlivierM. Leishmaniainduced increases in activation of macrophage SHP-1 tyrosine phosphatase are associated with impaired IFN-gamma-triggered JAK2 activation. Eur. J. Immunol.29, 3737–3744 (1999).
- Schwegmann A , BrombacherF. Host-directed drug targeting of factors hijacked by pathogens.Sci. Signal.1, re8 (2008).
- Gessner A , WillA, ViethM, SchroppelK, RollinghoffM. Stimulation of B-cell lymphopoiesis by interleukin-7 leads to aggravation of murine leishmaniasis.Immunology84, 416–422 (1995).
- Hoerauf A , SolbachW, LohoffM, RollinghoffM. The Xid defect determines an improved clinical course of murine leishmaniasis in susceptible mice.Int. Immunol.6, 1117–1124 (1994).
- Kima PE , ConstantSL, HannumLet al. Internalization of Leishmania mexicana complex amastigotes via the Fc receptor is required to sustain infection in murine cutaneous leishmaniasis. J. Exp. Med. 191, 1063–1068 (2000).
- Cosma CL , HumbertO, ShermanDR, RamakrishnanL. Trafficking of superinfecting Mycobacterium organisms into established granulomas occurs in mammals and is independent of the Erp and ESX-1 mycobacterial virulence loci. J. Infect. Dis.198, 1851–1855 (2008).
- Woronowicz A , De VusserK, LaroyWet al. Trypanosome trans-sialidase targets TrkA tyrosine kinase receptor and induces receptor internalization and activation. Glycobiology14, 987–998 (2004).
- Scharfstein J , SchmitzV, MorandiVet al. Host cell invasion by Trypanosoma cruzi is potentiated by activation of bradykinin B(2) receptors. J. Exp. Med. 192, 1289–1300 (2000).
- Araujo-Jorge TC , WaghabiMC, SoeiroMN, KeramidasM, BaillyS, FeigeJJ. Pivotal role for TGF-beta in infectious heart disease: the case of Trypanosoma cruzi infection and consequent Chagasic myocardiopathy. Cytokine Growth Factor Rev.19, 405–413 (2008).
- Reed SG . TGF-beta in infections and infectious diseases.Microbes Infect.1, 1313–1325 (1999).
- Blackwell JM . Receptors and recognition mechanisms of Leishmania species. Trans. R. Soc. Trop. Med. Hyg.79, 606–612 (1985).
- Kane MM , MosserDM. The role of IL-10 in promoting disease progression in leishmaniasis.J. Immunol.166, 1141–1147 (2001).
- Cummings HE , BarbiJ, RevillePet al. Critical role for phosphoinositide 3-kinase gamma in parasite invasion and disease progression of cutaneous leishmaniasis. Proc. Natl Acad. Sci. USA 109, 1251–1256 (2012).
- Williams O , HousemanBT, KunkelEJet al. Discovery of dual inhibitors of the immune cell PI3Ks p110delta and p110gamma: a prototype for new anti-inflammatory drugs. Chem. Biol. 17, 123–134 (2010).