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Editorial

Epigenetics and Epigenomics: The Future of Nutritional Interventions?

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Article: FSO237 | Received 10 Jul 2017, Accepted 17 Jul 2017, Published online: 15 Aug 2017

References

  • Waddington CH. The epigenotype. Int. J. Epidemiol. 41(1), 10–13 (2012).
  • Bernstein BE, Meissner A, Lander ES. The mammalian epigenome. Cell 128(4), 669–681 (2007).
  • Kanherkar RR, Bhatia-dey N, Csoka AB. Epigenetics across the human lifespan. Front. Cell. Dev. Biol. 2, 1–19 (2014).
  • Kucharski R, Maleszka J, Foret S, Maleszka R. Nutritional control of reproductive status in honeybees via DNA methylation. Science 319(5871), 1827–1830 (2008).
  • Gluckman PD, Hanson MA. Developmental origins of disease paradigm: a mechanistic and evolutionary perspective. Pediatr. Res. 56(3), 311–317 (2004).
  • Waterland RA, Jirtle RL. Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol. Cell. Biol. 23(15), 5293–5300 (2003).
  • Lee H-S, Barraza-Villarreal A, Hernandez-Vargas H et al. Modulation of DNA methylation states and infant immune system by dietary supplementation with ω-3 PUFA during pregnancy in an intervention study. Am. J. Clin. Nutr. 98(2), 480–487 (2013).
  • Altucci L, Rots MG. Epigenetic drugs: from chemistry via biology to medicine and back. Clin. Epigenetics 8, 56 (2016).
  • The Academy of Medical Sciences. Stratified, personalised or P4 medicine: a new direction for placing the patient at the centre of healthcare and health education. https://acmedsci.ac.uk/file-download/38266–56e6d483e1d21.pdf
  • Campión J, Milagro FI, Goyenechea E, Martínez JA. TNF-α promoter methylation as a predictive biomarker for weight-loss response. Obesity 17(6), 1293–1297 (2009).
  • Jenke AC, Postberg J, Raine T et al. DNA methylation analysis in the intestinal epithelium – effect of cell separation on gene expression and methylation profile. PLoS ONE 8(2), e55636 (2013).
  • Relton CL, Davey Smith G. Two-step epigenetic mendelian randomization: a strategy for establishing the causal role of epigenetic processes in pathways to disease. Int. J. Epidemiol. 41(1), 161–176 (2012).
  • Lauschke VM, Ivanov M, Ingelman-Sundberg M. Pitfalls and opportunities for epigenomic analyses focused on disease diagnosis, prognosis and therapy. Trends Pharmacol. Sci. doi:10.1016/j.tips.2017.05.007 (2017) ( Epub ahead of print).