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Commentary

Predicting In Vivo Behavior of injectable, In Situ-forming drug-delivery Systems

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Pages 479-483 | Received 10 Jan 2017, Accepted 19 Jan 2017, Published online: 28 Mar 2017

References

  • Mitra A Wu Y . Use of in vitro–in vivo correlation (IVIVC) to facilitate the development of polymer-based controlled release injectable formulations. Recent Pat. Drug Deliv. Formul.4 (2), 94–104 (2010).
  • Shen J Burgess DJ . In vitro–in vivo correlation for complex non-oral drug products: where do we stand?J. Control. Rel.219, 644–651 (2015).
  • Owen A Rannard S . Strengths, weaknesses, opportunities and challenges for long acting injectable therapies: insights for applications in HIV therapy. Adv. Drug Deliv. Rev. (2016).
  • Packhaeuser CB Schnieders J Oster CG Kissel T . In situ forming parenteral drug-delivery systems: an overview. Eur. J. Pharm. Biopharm.58 (2), 445–455 (2004).
  • Dunn RL English JP Cowsar DR Vanderbilt DP . Biodegradable in-situ forming implants and methods of producing the same. (1990).
  • Berges R Bello U . Effect of a new leuprorelin formulation on testosterone levels in patients with advanced prostate cancer. Curr. Med. Res. Opin.22 (4), 649–655 (2006).
  • Schulman C Alcaraz A Berges R Montorsi F Teillac P Tombal B . Expert opinion on 6-monthly luteinizing hormone-releasing hormone agonist treatment with the single-sphere depot system for prostate cancer. BJU Int.100 (Suppl. 1), 1–5 (2007).
  • Mchugh AJ . The role of polymer membrane formation in sustained release drug-delivery systems. J. Control. Rel.109 (1–3), 211–221 (2005).
  • Larsen C Larsen SW Jensen H Yaghmur A Østergaard J . Role of in vitro release models in formulation development and quality control of parenteral depots. Exp. Opin. Drug Deliv.6 (12), 1283–1295 (2009).
  • Solorio L Exner AA . Effect of the subcutaneous environment on phase-sensitive in situ-forming implant drug release, degradation, and microstructure. J. Pharm. Sci.104 (12), 4322–4328 (2015).
  • Kempe S Mader K . In situ forming implants–an attractive formulation principle for parenteral depot formulations. J. Control. Rel.161 (2), 668–679 (2012).
  • Graham PD Brodbeck KJ Mchugh AJ . Phase inversion dynamics of PLGA solutions related to drug delivery. J. Control. Rel.58 (2), 233–245 (1999).
  • Solorio L Sundarapandiyan D Olear A Exner AA . The effect of additives on the behavior of phase sensitive in situ forming implants. J. Pharm. Sci.104 (10), 3471–3480 (2015).
  • Brodbeck KJ Desnoyer JR Mchugh AJ . Phase inversion dynamics of PLGA solutions related to drug delivery. Part II. The role of solution thermodynamics and bath-side mass transfer. J. Control. Rel.62 (3), 333–344 (1999).
  • Burgess DJ Hussain AS Ingallinera TS Chen ML . Assuring quality and performance of sustained and controlled release parenterals: AAPS workshop report, co-sponsored by FDA and USP. Pharm. Res.19 (11), 1761–1768 (2002).
  • Hatefi A Amsden B . Biodegradable injectable in situ forming drug-delivery systems. J. Control. Rel.80 (1), 9–28 (2002).
  • Manaspon C Nittayacharn P Vejjasilpa K Fongsuk C Nasongkla N . SN-38: β-cyclodextrin inclusion complex for in situ solidifying injectable polymer implants. Presented at : Engineering in Medicine and Biology Society, EMBC, 2011 Annual International Conference of the IEEE. 3241–3244 (2011).
  • Do MP Neut C Metz H et al. In-situ forming composite implants for periodontitis treatment: How the formulation determines system performance. Int. J. Pharm.486 (1–2), 38–51 (2015).
  • Solorio L Patel RB Wu H Krupka T Exner AA . Advances in image-guided intratumoral drug delivery techniques. Ther. Deliv.1 (2), 307–322 (2010).
  • Patel RB Carlson AN Solorio L Exner AA . Characterization of formulation parameters affecting low molecular weight drug release from in situ forming drug-delivery systems. J. Biomed. Mater. Res. A94 (2), 476–484 (2010).
  • Beyer S Xie L Schmidt M et al. Optimizing novel implant formulations for the prolonged release of biopharmaceuticals using in vitro and in vivo imaging techniques. J. Control. Rel.235, 352–364 (2016).
  • Hernandez C Gawlik N Goss M et al. Macroporous acrylamide phantoms improve prediction of in vivo performance of in situ forming implants. J. Control. Rel.243, 225–231 (2016).
  • Solorio L Olear AM Hamilton JI et al. Noninvasive characterization of the effect of varying PLGA molecular weight blends on in situ forming implant behavior using ultrasound imaging. Theranostics2 (11), 1064–1077 (2012).
  • Zhou HY Gawlik A Hernandez C Goss M Mansour J Exner A . Nondestructive characterization of biodegradable polymer erosion in vivo using ultrasound elastography imaging. ACS Biomater. Sci. Eng.2 (6), 1005–1012 (2016).
  • Kim K Wagner WR . Non-invasive and non-destructive characterization of tissue engineered constructs using ultrasound imaging technologies: a review. Ann. Biomed. Eng.44 (3), 621–635 (2016).
  • Dalecki D Mercado KP Hocking DC . Quantitative ultrasound for nondestructive characterization of engineered tissues and biomaterials. Ann. Biomed. Eng.44 (3), 636–648 (2016).
  • Zhou J Hu W Tang L . Non-invasive characterization of immune responses to biomedical implants. Ann. Biomed. Eng.44 (3), 693–704 (2016).
  • Kim W Ferguson VL Borden M Neu CP . Application of elastography for the noninvasive assessment of biomechanics in engineered biomaterials and tissues. Ann. Biomed. Eng.44 (3), 705–724 (2016).
  • Parent M Nouvel C Koerber M Sapin A Maincent P Boudier A . PLGA in situ implants formed by phase inversion: critical physicochemical parameters to modulate drug release. J. Control. Rel.172 (1), 292–304 (2013).
  • Hulsart-Billstrom G Dawson J Hofmann S et al. A surprisingly poor correlation between in vitro and in vivo testing of biomaterials for bone regeneration: results of a multicentre analysis. Eur. Cell. Mater.31, 312–322 (2016).

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