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Therapeutic Delivery Volume 9, 2018 - Issue 10
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Research Article

Sodium Alginate Capsulation Increased Brain Delivery of Probucol and Suppressed Neuroinflammation and Neurodegeneration

John CL Mamo1 Curtin Health Innovation Research Institute, Curtin University, Perth, WAAustralia6845;2 School of Public Health, Faculty of Health Sciences, Curtin University, Perth, WAAustralia6845
,
Virginie Lam1 Curtin Health Innovation Research Institute, Curtin University, Perth, WAAustralia6845;2 School of Public Health, Faculty of Health Sciences, Curtin University, Perth, WAAustralia6845
,
Hani Al-Salami1 Curtin Health Innovation Research Institute, Curtin University, Perth, WAAustralia6845;3 School of Pharmacy & Biomedical Sciences, Faculty of Health Sciences, Curtin University, Perth, WA, 6845, Australia
,
Emily Brook1 Curtin Health Innovation Research Institute, Curtin University, Perth, WAAustralia6845;3 School of Pharmacy & Biomedical Sciences, Faculty of Health Sciences, Curtin University, Perth, WA, 6845, Australia
,
Armin Mooranian1 Curtin Health Innovation Research Institute, Curtin University, Perth, WAAustralia6845;3 School of Pharmacy & Biomedical Sciences, Faculty of Health Sciences, Curtin University, Perth, WA, 6845, Australia
,
Michael Nesbit1 Curtin Health Innovation Research Institute, Curtin University, Perth, WAAustralia6845;2 School of Public Health, Faculty of Health Sciences, Curtin University, Perth, WAAustralia6845
,
Liam Graneri1 Curtin Health Innovation Research Institute, Curtin University, Perth, WAAustralia6845;3 School of Pharmacy & Biomedical Sciences, Faculty of Health Sciences, Curtin University, Perth, WA, 6845, Australia
,
Zachary D'Alonzo1 Curtin Health Innovation Research Institute, Curtin University, Perth, WAAustralia6845;3 School of Pharmacy & Biomedical Sciences, Faculty of Health Sciences, Curtin University, Perth, WA, 6845, Australia
,
Nicholas Fimognari1 Curtin Health Innovation Research Institute, Curtin University, Perth, WAAustralia6845;3 School of Pharmacy & Biomedical Sciences, Faculty of Health Sciences, Curtin University, Perth, WA, 6845, Australia
,
Andrea Stephenson1 Curtin Health Innovation Research Institute, Curtin University, Perth, WAAustralia6845;3 School of Pharmacy & Biomedical Sciences, Faculty of Health Sciences, Curtin University, Perth, WA, 6845, Australia
&
Ryusuke Takechi1 Curtin Health Innovation Research Institute, Curtin University, Perth, WAAustralia6845;2 School of Public Health, Faculty of Health Sciences, Curtin University, Perth, WAAustralia6845Correspondence[email protected]
 show all
Pages 703-709 | Received 14 May 2018, Accepted 22 Aug 2018, Published online: 02 Oct 2018

References

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  • Mooranian A Negrulj R Takechi R et al. The biological effects of the hypolipidaemic drug probucol microcapsules fed daily for 4 weeks, to an insulin-resistant mouse model: potential hypoglycaemic and anti-inflammatory effects. Drug Deliv. Transl. Res.8 (3), 543–551 (2018).
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  • Kesaniemi YA Grundy SM . Influence of probucol on cholesterol and lipoprotein metabolism in man. J. Lipid Res.25 (8), 780–790 (1984).
  • Takechi R Galloway S Pallebage-Gamarallage MM Lam V Mamo JC . Dietary fats, cerebrovasculature integrity and Alzheimer's disease risk. Prog. Lipid Res.49 (2), 159–170 (2010).
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