Preparation, characterization and in vitro evaluation of 5-fluorouracil loaded into chitosan–acacia gum nanoparticles

References

• Gutschner T, Diederichs S. The hallmarks of cancer: a long non-coding RNA point of view. RNA Biol. 2012;9(6):703–719. doi:10.4161/rna.20481
   PubMed Web of Science ®Google Scholar
• Feitelson MA, Arzumanyan A, Kulathinal RJ et al. Sustained proliferation in cancer: mechanisms and novel therapeutic targets. Semin. Cancer Biol. 2015;35(Suppl.):S25–S54. doi:10.1016/j.semcancer.2015.02.006.
   PubMed Web of Science ®Google Scholar
• Zhang N, Yin Y, Xu SJ, Chen WS. 5-Fluorouracil: mechanisms of resistance and reversal strategies. Molecules 2008;13(8):1551–1569. doi:10.3390/molecules13081551
   PubMed Web of Science ®Google Scholar
• Touil Y, Igoudjil W, Corvaisier M et al. Colon cancer cells escape 5FU chemotherapy-induced cell death by entering stemness and quiescence associated with the c-Yes/YAP axis. Clin. Cancer Res. 2014;20(4):837–846. doi:10.1158/1078-0432.Ccr-13-1854
   PubMed Web of Science ®Google Scholar
• Showalter SL, Showalter TN, Witkiewicz A et al. Evaluating the drug-target relationship between thymidylate synthase expression and tumor response to 5-fluorouracil. Is it time to move forward? Cancer Biol. Ther. 2008;7(7):986–994. doi:10.4161/cbt.7.7.6181
   PubMed Web of Science ®Google Scholar
• Nsairat H, Khater D, Sayed U, Odeh F, Al Bawab A, Alshaer W. Liposomes: structure, composition, types, and clinical applications. Heliyon 2022;8(5):e09394. doi:https://doi.org/10.1016/j.heliyon.2022.e09394
   PubMed Web of Science ®Google Scholar
• Khater D, Nsairat H, Odeh F et al. Design, preparation, and characterization of effective dermal and transdermal lipid nanoparticles: a review. Cosmetics 2021;8(2):1–43.
   Google Scholar
• Al-Samydai A, Al Qaraleh M, Al Azzam KM et al. Formulating co-loaded nanoliposomes with gallic acid and quercetin for enhanced cancer therapy. Heliyon 2023;9(6):e17267. doi:10.1016/j.heliyon.2023.e17267
   PubMed Web of Science ®Google Scholar
• Nsairat H, Lafi Z, Al-Sulaibi M, Gharaibeh L, Alshaer W. Impact of nanotechnology on the oral delivery of phyto-bioactive compounds. Food Chem. 2023;424:136438. doi:10.1016/j.foodchem.2023.136438.
   PubMed Web of Science ®Google Scholar
• Yao Y, Zhou Y, Liu L et al. Nanoparticle-based drug delivery in cancer therapy and its role in overcoming drug resistance. Front. Mol. Biosci. 2020;7:193. doi:10.3389/fmolb.2020.00193
   PubMed Web of Science ®Google Scholar
• Mosleh-Shirazi S, Abbasi M, Moaddeli MR et al. Nanotechnology advances in the detection and treatment of cancer: an overview. Nanotheranostics 2022;6(4):400–423. doi:10.7150/ntno.74613
   PubMedGoogle Scholar
• Casadidio C, Peregrina DV, Gigliobianco MR, Deng S, Censi R, Di Martino P. Chitin and chitosans: characteristics, eco-friendly processes, and applications in cosmetic science. Mar. Drugs 2019;17(6):1–30. doi:10.3390/md17060369
   Web of Science ®Google Scholar
• Desai N, Rana D, Salave S et al. Chitosan: a potential biopolymer in drug delivery and biomedical applications. Pharmaceutics 2023;15(4):1–69. doi:10.3390/pharmaceutics15041313
   Web of Science ®Google Scholar
• Shakya AK, Al-Sulaibi M, Naik RR, Nsairat H, Suboh S, Abulaila A. Review on PLGA polymer based nanoparticles with antimicrobial properties and their application in various medical conditions or infections. Polymers [Internet] 2023;15(17):1–25.
   Google Scholar
• Ahmed A. Health benefits of gum arabic and medical use. Gum Arabic Elsevier London, UK 2018;183–210. doi:10.1016/B978-0-12-812002-6.00016-6
   Google Scholar
• Nag M, Lahiri D, Mukherjee D et al. Functionalized chitosan nanomaterials: a jammer for quorum sensing. Polymers [Internet] 2021;13(15):1–17.
   Google Scholar
• Yanat M, Schroën K. Preparation methods and applications of chitosan nanoparticles; with an outlook toward reinforcement of biodegradable packaging. Reactive and Funct. Poly. 2021;161:104849. doi:10.1016/j.reactfunctpolym.2021.104849
   Web of Science ®Google Scholar
• Karayianni M, Sentoukas T, Skandalis A, Pippa N, Pispas S. Chitosan-based nanoparticles for nucleic acid delivery: technological aspects, applications, and future perspectives. Pharmaceutics 2023;15(7):1–22. doi:10.3390/pharmaceutics15071849
   Web of Science ®Google Scholar
• Kalındemirtaş FD, Kariper İA, Sert E, Okşak N, Kuruca SE. The evaluation of anticancer activity by synthesizing 5FU loaded albumin nanoparticles by exposure to UV light. Toxicology In Vitro: An International Journal Published in Association with BIBRA 2022;84:105435. doi:10.1016/j.tiv.2022.105435
   PubMed Web of Science ®Google Scholar
• Udofot O, Affram K, Smith T, Tshabe B et al. Pharmacokinetic, biodistribution and therapeutic efficacy of 5-fluorouracil-loaded pH-sensitive PEGylated liposomal nanoparticles in HCT-116 tumor bearing mouse. J. Nat. Sci. 2016;2(1):1–16.
   Google Scholar
• Lopez JS, Banerji U. Combine and conquer: challenges for targeted therapy combinations in early phase trials. Na. Review. Clin. Oncol. 2017;14(1):57–66. doi:10.1038/nrclinonc.2016.96
   PubMed Web of Science ®Google Scholar
• Hoang NH, Le Thanh T, Sangpueak R et al. Chitosan nanoparticles-based ionic gelation method: a promising candidate for plant disease management. Polymers (Basel) 2022;14(4):1–28. doi:10.3390/polym14040662
   Web of Science ®Google Scholar
• Zhao Y, Wang Z, Zhang W, Jiang X. Adsorbed Tween 80 is unique in its ability to improve the stability of gold nanoparticles in solutions of biomolecules. Nanoscale 2010;2(10):2114–2119. doi:10.1039/c0nr00309c
   PubMed Web of Science ®Google Scholar
• Lobato Guarnido I, Luzon G, Ríos F, Fernández-Serrano M. Synthesis and characterization of environmentally friendly chitosan-arabic gum nanoparticles for encapsulation of oregano essential oil in pickering emulsion. Nanomaterials 2023;13:2651. doi:10.3390/nano13192651
   Web of Science ®Google Scholar
• Zvezdova D. Synthesis and characterization of chitosan from marine sources in Black Sea. Ann. Proc. 2010;49:65–69.
   Google Scholar
• Puvvada Y, Vankayalapati S, Sukhavasi S. Extraction of chitin and chitosan from exoskeleton of shrimp for application in the pharmaceutical industry. Int. Curr. Pharmaceut. J. 2012;1. doi:10.3329/icpj.v1i9.11616
   Google Scholar
• Sailakshmi G, Mitra DT, Gnanamani A. Engineering of chitosan and collagen macromolecules using sebacic acid for clinical applications. Progress Biomat. 2013;2. doi:10.1186/2194-0517-2-11
   PubMedGoogle Scholar
• Mitra DT, Sailakshmi G, Gnanamani A, Mandal A. Studies on cross-linking of succinic acid with chitosan/collagen. Materials Res. 2013;16:755–765. doi:10.1590/S1516-14392013005000059
   Web of Science ®Google Scholar
• Akinluwade K, Oyatogun G, Alebiowu G, Adeyemi I, Akinwole I. Synthesis and characterization of polymeric nanoparticles formed from cowry shells and acacia gum extracts. Journal of Advanc. Biol* & Biotechnol. 2017;14:1–8. doi:10.9734/JABB/2017/34880
   Google Scholar
• Adewunmi AA, Mahboob A, Kamal MS, Sultan A. Pickering emulsions stabilized by chitosan/natural acacia gum biopolymers: effects of pH and salt concentrations. Polymers (Basel) 2022;14(23):1–13. doi:10.3390/polym14235270
   Web of Science ®Google Scholar
• Rawla P, Sunkara T, Barsouk A. Epidemiology of colorectal cancer: incidence, mortality, survival, and risk factors. Przeglad. Gastroenterologiczny 2019;14(2):89–103. doi:10.5114/pg.2018.81072
   PubMed Web of Science ®Google Scholar
• Sarkar S, Horn G, Moulton K et al. Cancer development, progression, and therapy: an epigenetic overview. Int. J. Mol. Sci. 2013;14(10):21087–21113. doi:10.3390/ijms141021087
   PubMed Web of Science ®Google Scholar
• Dekker E, Tanis PJ, Vleugels JLA, Kasi PM, Wallace MB. Colorectal cancer. Lancet 2019;394(10207):1467–1480. doi:10.1016/s0140-6736(19)32319-0
   PubMed Web of Science ®Google Scholar
• Van der Jeught K, Xu HC, Li YJ, Lu XB, Ji G. Drug resistance and new therapies in colorectal cancer. World J. Gastroenterol. 2018;24(34):3834–3848. doi:10.3748/wjg.v24.i34.3834
   PubMed Web of Science ®Google Scholar
• Entezar-Almahdi E, Mohammadi-Samani S, Tayebi L, Farjadian F. Recent advances in designing 5-fluorouracil delivery systems: a stepping stone in the safe treatment of colorectal cancer. Int. J. Nanomed. 2020;15:5445–5458. doi:10.2147/ijn.S257700
   PubMed Web of Science ®Google Scholar
• Xiao X, Teng F, Shi C, Chen J, Wu S, Wang B et al. Polymeric nanoparticles-Promising carriers for cancer therapy. Front. Bioengin. Biotechnol. 2022;10:1024143. doi:10.3389/fbioe.2022.1024143
   PubMed Web of Science ®Google Scholar
• Alli YA, Ejeromedoghene O, Oladoye PO, Bamisaye A, Oladoyinbo FO, Adewuyi S et al. Hydrogen-assisted green synthesis of trimethyl chitosan gold nanoparticles. Kuwait J. Sci. 2023:100162. doi:https://doi.org/10.1016/j.kjs.2023.12.002
   Web of Science ®Google Scholar
• Herdiana Y. Chitosan nanoparticles for gastroesophageal reflux disease treatment. Polymers [Internet] 2023;15(16):1–29.
   Google Scholar
• Sultan M, Elsayed H, Abdelhakim AEF, Taha G. Active packaging gelatin films based on chitosan/Arabic gum/coconut oil Pickering nano emulsions. J. Appl. Poly. Sci. 2022;139(1):51442. doi:10.1002/app.51442
   Web of Science ®Google Scholar
• Németh Z, Csóka I, Semnani Jazani R et al. Quality by design-driven zeta potential optimisation study of liposomes with charge imparting membrane additives. Pharmaceutics 2022;14(9):1–25. doi:10.3390/pharmaceutics14091798
   Web of Science ®Google Scholar