References
- Morgan P , Van Der Graaf PH. Can theflow of medicines be improved? Fundamental pharmacokinetic and pharmacological principles toward improving Phase II survival. Drug Discov. Today doi:10.1016/j.drudis.2011.12.020 (2012) (Epub ahead of print).
- Zhang GZ . Crystalline solid dispersions. Formulation strategies for poorly soluble drugs. Presented at: AAPS 45th Annual Arden Conference. West Point, NY, USA, 1–8 February 2010.
- McConnell EL , FaddaHM, BasitAW. Gut instincts: explorations in intestinal physiology and drug delivery. Int. J. Pharm.364(2), 213–226 (2008).
- Sutton SC . The use of gastrointestinal intubation studies for controlled release development. Br. J. Clin. Pharm.68(3), 342–354 (2009).
- Wilding I , HirstP, ConnorA. Development of an engineering based capsule for human drug absorption studies. Pharm. Sci. Tech. Today3(11), 385–392 (2000).
- Reddy M , ConnorA, BrennanBJet al. Physiological modelling and assessment of regional drug bioavailability of danoprevir to determine whether a controlled released formulation is feasible. Biopharm. Drug Disp. 32(5), 261–275 (2011).
- Basit AW , PodczeckF, NewtonJM, WaddingtonWA, EllPJ, LaceyLF. The use of formulation technology to assess regional gastrointestinal drug absorption in humans. Eur. J. Pharm. Sci.21(2–3), 179–189 (2004).
- Bergstrand M , SöderlindE, ErikssonUG, WeitschiesW, KarlssonMO. A semi-mechanistic modeling strategy for characterization of regional absorption properties and prospective prediction of plasma concentrations following administration of new modified release formulations. Pharm. Res.29(2), 574–584 (2012).
- Kararli TT . Comparison of the gastrointestinal anatomy, physiology and biochemistry of humans and commonly used laboratory animals. Biopharm. Drug Disp.16(5), 351–380 (1995).
- Tannergren C , BergendalA, LennernäsH, AbrahamssonB. Toward an increased understanding of the barriers to colonic drug absorption in humans: implications for early controlled release candidate assessment. Mol. Pharm.6(1), 60–73 (2009).