1,510
Views
33
CrossRef citations to date
0
Altmetric
RESEARCH PAPERS

Epigenome-wide analysis of neonatal CD4+ T-cell DNA methylation sites potentially affected by maternal fish oil supplementation

, , , , &
Pages 1570-1576 | Received 22 Jul 2014, Accepted 17 Oct 2014, Published online: 27 Jan 2015

References

  • Dunstan JA, Mori TA, Barden A, Beilin LJ, Taylor AL, Holt PG, Prescott SL. Fish oil supplementation in pregnancy modifies neonatal allergen-specific immune responses and clinical outcomes in infants at high risk of atopy: a randomized, controlled trial. J Allergy Clin Immunol 2003 Dec; 112(6):1178-84; PMID:14657879; http://dx.doi.org/10.1016/j.jaci.2003.09.009
  • Palmer DJ, Sullivan T, Gold MS, Prescott SL, Heddle R, Gibson RA, Makrides M. Effect of n-3 long chain polyunsaturated fatty acid supplementation in pregnancy on infants’ allergies in first year of life: randomised controlled trial. BMJ 2012; 344:e184; PMID:22294737; http://dx.doi.org/10.1136/bmj.e184
  • Klemens CM, Berman DR, Mozurkewich EL. The effect of perinatal omega-3 fatty acid supplementation on inflammatory markers and allergic diseases: a systematic review. BJOG 2011 Jul; 118(8):916-25; PMID:21658192; http://dx.doi.org/10.1111/j.1471-0528.2010.02846.x
  • Skilton MR, Ayer JG, Harmer JA, Webb K, Leeder SR, Marks GB, Celermajer DS. Impaired fetal growth and arterial wall thickening: a randomized trial of omega-3 supplementation. Pediatrics 2012 Mar; 129(3):e698-703; PMID:22351892; http://dx.doi.org/10.1542/peds.2011-2472
  • Forsyth JS, Willatts P, Agostoni C, Bissenden J, Casaer P, Boehm G. Long chain polyunsaturated fatty acid supplementation in infant formula and blood pressure in later childhood: follow up of a randomised controlled trial. BMJ 2003 May 3;326(7396):953; PMID:12727766; http://dx.doi.org/10.1136/bmj.326.7396.953
  • Innis SM. Metabolic programming of long-term outcomes due to fatty acid nutrition in early life. Matern Child Nutr 2011 Apr; 7 Suppl 2:112-23; PMID:21366871; http://dx.doi.org/10.1111/j.1740-8709.2011.00318.x
  • Prescott SL, Barden AE, Mori TA, Dunstan JA. Maternal fish oil supplementation in pregnancy modifies neonatal leukotriene production by cord-blood-derived neutrophils. Clin Sci (Lond) 2007 Nov; 113(10):409-16; PMID:17596121
  • Barden AE, Mori TA, Dunstan JA, Taylor AL, Thornton CA, Croft KD, Beilin LJ, Prescott SL. Fish oil supplementation in pregnancy lowers F2-isoprostanes in neonates at high risk of atopy. Free Radic Res 2004 Mar; 38(3):233-9; PMID:15129731; http://dx.doi.org/10.1080/10715760310001656722
  • Prescott SL, Irvine J, Dunstan JA, Hii C, Ferrante A. Protein kinase Czeta: a novel protective neonatal T-cell marker that can be upregulated by allergy prevention strategies. J Allergy Clin Immunol 2007 Jul; 120(1):200-6; PMID:17544492; http://dx.doi.org/10.1016/j.jaci.2007.03.045
  • McKay JA, Mathers JC. Diet induced epigenetic changes and their implications for health. Acta Physiol (Oxf) 2011 Jun; 202(2):103-18; PMID:21401888
  • Ceccarelli V, Racanicchi S, Martelli MP, Nocentini G, Fettucciari K, Riccardi C, Marconi P, Di Nardo P, Grignani F, Binaglia L, et al. Eicosapentaenoic acid demethylates a single CpG that mediates expression of tumor suppressor CCAAT/enhancer-binding protein delta in U937 leukemia cells. J Biol Chem 2011 Aug 5; 286(31):27092-102; PMID:21659508; http://dx.doi.org/10.1074/jbc.M111.253609
  • Sadli N, Ackland ML, De Mel D, Sinclair AJ, Suphioglu C. Effects of zinc and DHA on the epigenetic regulation of human neuronal cells. Cell Physiol Biochem 2012; 29(1-2):87-98; PMID:22415078; http://dx.doi.org/10.1159/000337590
  • Cho Y, Turner ND, Davidson LA, Chapkin RS, Carroll RJ, Lupton JR. Colon cancer cell apoptosis is induced by combined exposure to the n-3 fatty acid docosahexaenoic acid and butyrate through promoter methylation. Exp Biol Med (Maywood) 2014 Mar; 239(3):302-10; PMID:24495951; http://dx.doi.org/10.1177/1535370213514927
  • Aslibekyan S, Wiener HW, Havel PJ, Stanhope KL, O’Brien DM, Hopkins SE, Absher DM, Tiwari HK, Boyer BB. DNA methylation patterns are associated with n-3 fatty acid intake in Yup’ik people. J Nutr 2014 Apr; 144(4):425-30; PMID:24477300; http://dx.doi.org/10.3945/jn.113.187203
  • Hermsdorff HH, Mansego ML, Campion J, Milagro FI, Zulet MA, Martinez JA. TNF-alpha promoter methylation in peripheral white blood cells: relationship with circulating TNFalpha, truncal fat and n-6 PUFA intake in young women. Cytokine 2013 Oct; 64(1):265-71; PMID:23796695; http://dx.doi.org/10.1016/j.cyto.2013.05.028
  • Hoile SP, Irvine NA, Kelsall CJ, Sibbons C, Feunteun A, Collister A, Torrens C, Calder PC, Hanson MA, Lillycrop KA, et al. Maternal fat intake in rats alters 20:4n-6 and 22:6n-3 status and the epigenetic regulation of Fads2 in offspring liver. J Nutr Biochem 2013 Jul; 24(7):1213-20; PMID:23107313; http://dx.doi.org/10.1016/j.jnutbio.2012.09.005
  • Niculescu MD, Lupu DS, Craciunescu CN. Perinatal manipulation of alpha-linolenic acid intake induces epigenetic changes in maternal and offspring livers. FASEB J 2013 Jan; 27(1):350-8; http://dx.doi.org/10.1096/fj.12-210724
  • Lee HS, Barraza-Villarreal A, Hernandez-Vargas H, Sly PD, Biessy C, Ramakrishnan U, Romieu I, Herceg Z. Modulation of DNA methylation states and infant immune system by dietary supplementation with omega-3 PUFA during pregnancy in an intervention study. Am J Clin Nutr 2013 Aug; 98(2):480-7; http://dx.doi.org/10.3945/ajcn.112.052241
  • Amarasekera M, Martino D, Ashley S, Harb H, Kesper D, Strickland D, Saffery R, Prescott SL. Genome-wide DNA methylation profiling identifies a folate-sensitive region of differential methylation upstream of ZFP57-imprinting regulator in humans. FASEB J 2014 Jun 2.
  • Martino D, Joo JE, Sexton-Oates A, Dang T, Allen K, Saffery R, Prescott S. Epigenome-wide association study reveals longitudinally stable DNA methylation differences in CD4+ T cells from children with IgE-mediated food allergy. Epigenetics 2014 Apr 24; 9(7); http://dx.doi.org/10.4161/epi.28945
  • Prescott SL. Early-life environmental determinants of allergic diseases and the wider pandemic of inflammatory noncommunicable diseases. J Allergy Clin Immunol 2013 Jan; 131(1):23-30; PMID:23265694; http://dx.doi.org/10.1016/j.jaci.2012.11.019
  • Martino DJ, Prescott SL. Silent mysteries: epigenetic paradigms could hold the key to conquering the epidemic of allergy and immune disease. Allergy 2010 Jan; 65(1):7-15; http://dx.doi.org/10.1111/j.1398-9995.2009.02186.x
  • Amarasekera M, Prescott SL, Palmer DJ. Nutrition in early life, immune-programming and allergies: the role of epigenetics. Asian Pac J Allergy Immunol. 2013 Sep; 31(3 175-82.
  • Adalsteinsson BT, Gudnason H, Aspelund T, Harris TB, Launer LJ, Eiriksdottir G, Smith AV, Gudnason V. Heterogeneity in white blood cells has potential to confound DNA methylation measurements. PLoS One 2012; 7(10):e46705; http://dx.doi.org/10.1371/journal.pone.0046705
  • Martino DJ, Tulic MK, Gordon L, Hodder M, Richman T, Metcalfe J, Prescott SL, Saffery R. Evidence for age-related and individual-specific changes in DNA methylation profile of mononuclear cells during early immune development in humans. Epigenetics 2011 Sep 1; 6(9).
  • Dunstan JA, Roper J, Mitoulas L, Hartmann PE, Simmer K, Prescott SL. The effect of supplementation with fish oil during pregnancy on breast milk immunoglobulin A, soluble CD14, cytokine levels and fatty acid composition. Clin Exp Allergy 2004 Aug; 34(8):1237-42; PMID:15298564; http://dx.doi.org/10.1111/j.1365-2222.2004.02028.x
  • Aryee MJ, Jaffe AE, Corrada-Bravo H, Ladd-Acosta C, Feinberg AP, Hansen KD, Irizarry RA. Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays. Bioinformatics 2014 May 15; 30(10):1363-9; PMID:24478339; http://dx.doi.org/10.1093/bioinformatics/btu049
  • Chen YA, Lemire M, Choufani S, Butcher DT, Grafodatskaya D, Zanke BW, Gallinger S, Hudson TJ, Weksberg R. Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray. Epigenetics 2013 Feb; 8(2):203-9; PMID:23314698; http://dx.doi.org/10.4161/epi.23470
  • Leek JT, Storey JD. Capturing heterogeneity in gene expression studies by surrogate variable analysis. PLoS Genet 2007 Sep; 3(9):1724-35.
  • Smyth GK. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 2004; 3:Article3; PMID:16646809
  • Barfield RT, Kilaru V, Smith AK, Conneely KN. CpGassoc: an R function for analysis of DNA methylation microarray data. Bioinformatics. 2012 May 1; 28(9):1280-1; PMID:22451269; http://dx.doi.org/10.1093/bioinformatics/bts124
  • Benjamini Y HY. Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing. JSTOR 1995; 57(1):289-300.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.