Bacterial bile salt hydrolase in host metabolism: Potential for influencing gastrointestinal microbe-host crosstalk

References

• Qin J, Li R, Raes J, Arumugam M, Burgdorf KS, Manichanh C, et al. A human gut microbial gene catalogue established by metagenomic sequencing. Nature 2010; 464:59-65; PMID:20203603; http://dx.doi.org/10.1038/nature08821
   PubMed Web of Science ®Google Scholar
• Tong M, Li X, Wegener Parfrey L, Roth B, Ippoliti A, Wei B, et al. A modular organization of the human intestinal mucosal microbiota and its association with inflammatory bowel disease. PLoS One 2013; 8:e80702; PMID:24260458; http://dx.doi.org/10.1371/journal.pone.0080702
   PubMed Web of Science ®Google Scholar
• Karlsson FH, Tremaroli V, Nookaew I, Bergstrom G, Behre CJ, Fagerberg B, et al. Gut metagenome in European women with normal, impaired and diabetic glucose control. Nature 2013; 498:99-103; PMID:23719380; http://dx.doi.org/10.1038/nature12198
   PubMed Web of Science ®Google Scholar
• Le Chatelier E, Nielsen T, Qin J, Prifti E, Hildebrand F, Falony G, et al. Richness of human gut microbiome correlates with metabolic markers. Nature 2013; 500:541-6; PMID:23985870; http://dx.doi.org/10.1038/nature12506
   PubMed Web of Science ®Google Scholar
• Joyce SA, Gahan CG. The gut microbiota and the metabolic health of the host. Curr Opin Gastroenterol 2014; 30:120-7; PMID:24468803; http://dx.doi.org/10.1097/MOG.0000000000000039
   PubMed Web of Science ®Google Scholar
• Angelakis E, Merhej V, Raoult D. Related actions of probiotics and antibiotics on gut microbiota and weight modification. Lancet Infect Dis 2013; 13:889-99; PMID:24070562; http://dx.doi.org/10.1016/S1473-3099(13)70179-8
   PubMed Web of Science ®Google Scholar
• Clarke SF, Murphy EF, Nilaweera K, Ross PR, Shanahan F, O'Toole PW, et al. The gut microbiota and its relationship to diet and obesity: new insights. Gut Microbes 2012; 3:186-202; PMID:22572830; http://dx.doi.org/10.4161/gmic.20168
   PubMed Web of Science ®Google Scholar
• Nieuwdorp M, Gilijamse PW, Pai N, Kaplan LM. Role of the microbiome in energy regulation and metabolism. Gastroenterology 2014; 146:1525-33; PMID:24560870; http://dx.doi.org/10.1053/j.gastro.2014.02.008
   PubMed Web of Science ®Google Scholar
• Everard A, Cani PD. Diabetes, obesity and gut microbiota. Best Pract Res Clin Gastroenterol 2013; 27:73-83; PMID:23768554; http://dx.doi.org/10.1016/j.bpg.2013.03.007
   PubMed Web of Science ®Google Scholar
• Turnbaugh PJ, Ley RE, Mahowald MA, Magrini V, Mardis ER, Gordon JI. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 2006; 444:1027-31; PMID:17183312; http://dx.doi.org/10.1038/nature05414
   PubMed Web of Science ®Google Scholar
• Ley RE, Turnbaugh PJ, Klein S, Gordon JI. Microbial ecology: human gut microbes associated with obesity. Nature 2006; 444:1022-3; PMID:17183309; http://dx.doi.org/10.1038/4441022a
   PubMed Web of Science ®Google Scholar
• Murphy EF, Cotter PD, Healy S, Marques TM, O'Sullivan O, Fouhy F, et al. Composition and energy harvesting capacity of the gut microbiota: relationship to diet, obesity and time in mouse models. Gut 2010; 59:1635-42; PMID:20926643; http://dx.doi.org/10.1136/gut.2010.215665
   PubMed Web of Science ®Google Scholar
• Ridaura VK, Faith JJ, Rey FE, Cheng J, Duncan AE, Kau AL, et al. Gut microbiota from twins discordant for obesity modulate metabolism in mice. Science 2013; 341:1241214; PMID:24009397; http://dx.doi.org/10.1126/science.1241214
   PubMed Web of Science ®Google Scholar
• Cani PD, Amar J, Iglesias MA, Poggi M, Knauf C, Bastelica D, et al. Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes 2007; 56:1761-72; PMID:17456850; http://dx.doi.org/10.2337/db06-1491
   PubMed Web of Science ®Google Scholar
• Creely SJ, McTernan PG, Kusminski CM, Fisher fM, Da Silva NF, Khanolkar M, et al. Lipopolysaccharide activates an innate immune system response in human adipose tissue in obesity and type 2 diabetes. Am J Physiol Endocrinol Metab 2007; 292:E740-7; PMID:17090751; http://dx.doi.org/10.1152/ajpendo.00302.2006
   PubMed Web of Science ®Google Scholar
• Karlsson CL, Onnerfalt J, Xu J, Molin G, Ahrne S, Thorngren-Jerneck K. The microbiota of the gut in preschool children with normal and excessive body weight. Obesity (Silver Spring) 2012; 20:2257-61; PMID:22546742; http://dx.doi.org/10.1038/oby.2012.110
   PubMed Web of Science ®Google Scholar
• Everard A, Belzer C, Geurts L, Ouwerkerk JP, Druart C, Bindels LB, et al. Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity. Proc Natl Acad Sci U S A 2013; 110:9066-71; PMID:23671105; http://dx.doi.org/10.1073/pnas.1219451110
   PubMed Web of Science ®Google Scholar
• Sayin SI, Wahlstrom A, Felin J, Jantti S, Marschall HU, Bamberg K, et al. Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-β-muricholic acid, a naturally occurring FXR antagonist. Cell Metab 2013; 17:225-35; PMID:23395169; http://dx.doi.org/10.1016/j.cmet.2013.01.003
   PubMed Web of Science ®Google Scholar
• Watanabe M, Houten SM, Mataki C, Christoffolete MA, Kim BW, Sato H, et al. Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation. Nature 2006; 439:484-9; PMID:16400329; http://dx.doi.org/10.1038/nature04330
   PubMed Web of Science ®Google Scholar
• Joyce SA, MacSharry J, Casey PG, Kinsella M, Murphy EF, Shanahan F, et al. Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut. Proc Natl Acad Sci U S A 2014; 111:7421-6; PMID:24799697; http://dx.doi.org/10.1073/pnas.1323599111
   PubMed Web of Science ®Google Scholar
• Begley M, Gahan CG, Hill C. The interaction between bacteria and bile. FEMS Microbiol Rev 2005; 29:625-51; PMID:16102595; http://dx.doi.org/10.1016/j.femsre.2004.09.003
   PubMed Web of Science ®Google Scholar
• Begley M, Hill C, Gahan CG. Bile salt hydrolase activity in probiotics. Appl Environ Microbiol 2006; 72:1729-38; PMID:16517616; http://dx.doi.org/10.1128/AEM.72.3.1729-1738.2006
   PubMed Web of Science ®Google Scholar
• Lin J. Antibiotic growth promoters enhance animal production by targeting intestinal bile salt hydrolase and its producers. Front Microbiol 2014; 5:33; PMID:24575079; .
   PubMedGoogle Scholar
• Smith K, Zeng X, Lin J. Discovery of bile salt hydrolase inhibitors using an efficient high-throughput screening system. PLoS One 2014; 9:e85344; PMID:24454844; http://dx.doi.org/10.1371/journal.pone.0085344
   PubMedGoogle Scholar
• Jones BV, Begley M, Hill C, Gahan CG, Marchesi JR. Functional and comparative metagenomic analysis of bile salt hydrolase activity in the human gut microbiome. Proc Natl Acad Sci U S A 2008; 105:13580-5; PMID:18757757; http://dx.doi.org/10.1073/pnas.0804437105
   PubMed Web of Science ®Google Scholar
• Fang F, Li Y, Bumann M, Raftis EJ, Casey PG, Cooney JC, et al. Allelic variation of bile salt hydrolase genes in Lactobacillus salivarius does not determine bile resistance levels. J Bacteriol 2009; 191:5743-57; PMID:19592587; http://dx.doi.org/10.1128/JB.00506-09
   PubMed Web of Science ®Google Scholar
• de Aguiar Vallim TQ, Tarling EJ, Edwards PA. Pleiotropic roles of bile acids in metabolism. Cell Metab 2013; 17:657-69; PMID:23602448; http://dx.doi.org/10.1016/j.cmet.2013.03.013
   PubMed Web of Science ®Google Scholar
• Houten SM, Watanabe M, Auwerx J. Endocrine functions of bile acids. EMBO J 2006; 25:1419-25; PMID:16541101; http://dx.doi.org/10.1038/sj.emboj.7601049
   PubMed Web of Science ®Google Scholar
• Swann JR, Want EJ, Geier FM, Spagou K, Wilson ID, Sidaway JE, et al. Systemic gut microbial modulation of bile acid metabolism in host tissue compartments. Proc Natl Acad Sci U S A 2011; 108(Suppl 1):4523-30; PMID:20837534; http://dx.doi.org/10.1073/pnas.1006734107
   PubMed Web of Science ®Google Scholar
• Jones ML, Tomaro-Duchesneau C, Martoni CJ, Prakash S. Cholesterol lowering with bile salt hydrolase-active probiotic bacteria, mechanism of action, clinical evidence, and future direction for heart health applications. Expert Opin Biol Ther 2013; 13:631-42; PMID:23350815; http://dx.doi.org/10.1517/14712598.2013.758706
   PubMed Web of Science ®Google Scholar
• Vaishnava S, Yamamoto M, Severson KM, Ruhn KA, Yu X, Koren O, et al. The antibacterial lectin RegIIIgamma promotes the spatial segregation of microbiota and host in the intestine. Science 2011; 334:255-8; PMID:21998396; http://dx.doi.org/10.1126/science.1209791
   PubMed Web of Science ®Google Scholar
• Islam KB, Fukiya S, Hagio M, Fujii N, Ishizuka S, Ooka T, et al. Bile acid is a host factor that regulates the composition of the cecal microbiota in rats. Gastroenterology 2011; 141:1773-81; PMID:21839040; http://dx.doi.org/10.1053/j.gastro.2011.07.046
   PubMed Web of Science ®Google Scholar
• Yokota A, Fukiya S, Islam KB, Ooka T, Ogura Y, Hayashi T, et al. Is bile acid a determinant of the gut microbiota on a high-fat diet? Gut Microbes 2012; 3:455-9; PMID:22825495; http://dx.doi.org/10.4161/gmic.21216
   PubMedGoogle Scholar
• Inagaki T, Moschetta A, Lee YK, Peng L, Zhao G, Downes M, et al. Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor. Proc Natl Acad Sci U S A 2006; 103:3920-5; PMID:16473946; http://dx.doi.org/10.1073/pnas.0509592103
   PubMed Web of Science ®Google Scholar
• Ichikawa R, Takayama T, Yoneno K, Kamada N, Kitazume MT, Higuchi H, et al. Bile acids induce monocyte differentiation toward interleukin-12 hypo-producing dendritic cells via a TGR5-dependent pathway. Immunology 2012; 136:153-62; PMID:22236403; http://dx.doi.org/10.1111/j.1365-2567.2012.03554.x
   PubMed Web of Science ®Google Scholar
• Ryan KK, Tremaroli V, Clemmensen C, Kovatcheva-Datchary P, Myronovych A, Karns R, et al. FXR is a molecular target for the effects of vertical sleeve gastrectomy. Nature 2014; 509:183-8; PMID:24670636; http://dx.doi.org/10.1038/nature13135
   PubMed Web of Science ®Google Scholar
• Backhed F, Manchester JK, Semenkovich CF, Gordon JI. Mechanisms underlying the resistance to diet-induced obesity in germ-free mice. Proc Natl Acad Sci U S A 2007; 104:979-84; PMID:17210919; http://dx.doi.org/10.1073/pnas.0605374104
   PubMed Web of Science ®Google Scholar
• Bass J. Circadian topology of metabolism. Nature 2012; 491:348-56; PMID:23151577; http://dx.doi.org/10.1038/nature11704
   PubMed Web of Science ®Google Scholar
• Ekmekcioglu C, Touitou Y. Chronobiological aspects of food intake and metabolism and their relevance on energy balance and weight regulation. Obes Rev 2011; 12:14-25; PMID:20122134; http://dx.doi.org/10.1111/j.1467-789X.2010.00716.x
   PubMed Web of Science ®Google Scholar
• Mukherji A, Kobiita A, Ye T, Chambon P. Homeostasis in intestinal epithelium is orchestrated by the circadian clock and microbiota cues transduced by TLRs. Cell 2013; 153:812-27; PMID:23663780; http://dx.doi.org/10.1016/j.cell.2013.04.020
   PubMed Web of Science ®Google Scholar
• Li YC, Wang DP, Chiang JY. Regulation of cholesterol 7 α-hydroxylase in the liver. Cloning, sequencing, and regulation of cholesterol 7 α-hydroxylase mRNA. J Biol Chem 1990; 265:12012-9; PMID:1694852; .
   PubMed Web of Science ®Google Scholar
• Zhang YK, Guo GL, Klaassen CD. Diurnal variations of mouse plasma and hepatic bile acid concentrations as well as expression of biosynthetic enzymes and transporters. PLoS One 2011; 6:e16683
   PubMed Web of Science ®Google Scholar
• Degirolamo C, Rainaldi S, Bovenga F, Murzilli S, Moschetta A. Microbiota modification with probiotics induces hepatic bile acid synthesis via downregulation of the Fxr-Fgf15 axis in mice. Cell Rep 2014; 7:12-8; PMID:24656817; http://dx.doi.org/10.1016/j.celrep.2014.02.032
   PubMed Web of Science ®Google Scholar
• Jones ML, Martoni CJ, Prakash S. Cholesterol lowering and inhibition of sterol absorption by Lactobacillus reuteri NCIMB 30242: a randomized controlled trial. Eur J Clin Nutr 2012; 66:1234-41; PMID:22990854; http://dx.doi.org/10.1038/ejcn.2012.126
   PubMed Web of Science ®Google Scholar
• Li F, Jiang C, Krausz KW, Li Y, Albert I, Hao H, et al. Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity. Nat Commun 2013; 4:2384; PMID:24064762; .
   PubMed Web of Science ®Google Scholar
• De Vadder F, Kovatcheva-Datchary P, Goncalves D, Vinera J, Zitoun C, Duchampt A, et al. Microbiota-generated metabolites promote metabolic benefits via gut-brain neural circuits. Cell 2014; 156:84-96; PMID:24412651; http://dx.doi.org/10.1016/j.cell.2013.12.016
   PubMed Web of Science ®Google Scholar
• Choi SB, Lew LC, Yeo SK, Nair Parvathy S, Liong MT. Probiotics and the BSH-related cholesterol lowering mechanism: a Jekyll and Hyde scenario. Crit Rev Biotechnol 2014; PMID:24575869; .
   PubMedGoogle Scholar
• Ajouz H, Mukherji D, Shamseddine A. Secondary bile acids: an underrecognized cause of colon cancer. World J Surg Oncol 2014; 12:164; PMID:24884764; http://dx.doi.org/10.1186/1477-7819-12-164
   PubMed Web of Science ®Google Scholar
• Maran RR, Thomas A, Roth M, Sheng Z, Esterly N, Pinson D, et al. Farnesoid X receptor deficiency in mice leads to increased intestinal epithelial cell proliferation and tumor development. J Pharmacol Exp Ther 2009; 328:469-77; PMID:18981289; http://dx.doi.org/10.1124/jpet.108.145409
   PubMed Web of Science ®Google Scholar
• Modica S, Murzilli S, Salvatore L, Schmidt DR, Moschetta A. Nuclear bile acid receptor FXR protects against intestinal tumorigenesis. Cancer Res 2008; 68:9589-94; PMID:19047134; http://dx.doi.org/10.1158/0008-5472.CAN-08-1791
   PubMed Web of Science ®Google Scholar
• Guban J, Korver DR, Allison GE, Tannock GW. Relationship of dietary antimicrobial drug administration with broiler performance, decreased population levels of Lactobacillus salivarius, and reduced bile salt deconjugation in the ileum of broiler chickens. Poult Sci 2006; 85:2186-94; PMID:17135676; http://dx.doi.org/10.1093/ps/85.12.2186
   PubMed Web of Science ®Google Scholar
• Vrieze A, Out C, Fuentes S, Jonker L, Reuling I, Kootte RS, et al. Impact of oral vancomycin on gut microbiota, bile acid metabolism, and insulin sensitivity. J Hepatol 2014; 60:824-31; PMID:24316517; http://dx.doi.org/10.1016/j.jhep.2013.11.034
   PubMed Web of Science ®Google Scholar
• Wang Z, Zeng X, Mo Y, Smith K, Guo Y, Lin J. Identification and characterization of a bile salt hydrolase from Lactobacillus salivarius for development of novel alternatives to antibiotic growth promoters. Appl Environ Microbiol 2012; 78:8795-802; PMID:23064348; http://dx.doi.org/10.1128/AEM.02519-12
   PubMedGoogle Scholar