1,301
Views
7
CrossRef citations to date
0
Altmetric
AUTHOR'S VIEW

TAK1-dependent autophagy: A suppressor of fatty liver disease and hepatic oncogenesis

Article: e968507 | Received 19 Aug 2014, Accepted 20 Aug 2014, Published online: 31 Dec 2014

References

  • Roh YS, Song J, Seki E. TAK1 regulates hepatic cell survival and carcinogenesis. J Gastroenterol 2014; 49:185-194; PMID:24443058; http://dx.doi.org/10.1007/s00535-013-0931-x
  • Inokuchi S, Aoyama T, Miura K, Osterreicher CH, Kodama Y, Miyai K, Akira S, Brenner DA, Seki E. Disruption of TAK1 in hepatocytes causes hepatic injury, inflammation, fibrosis, and carcinogenesis. Proc Natl Acad Sci U S A 2010; 107:844-849; PMID:20080763; http://dx.doi.org/10.1073/pnas.0909781107
  • Bettermann K, Vucur M, Haybaeck J, Koppe C, Janssen J, Heymann F, Weber A, Weiskirchen R, Liedtke C, Gassler N, et al. TAK1 suppresses a NEMO-dependent but NF-kappaB-independent pathway to liver cancer. Cancer Cell 2010; 17:481-496; PMID:20478530; http://dx.doi.org/10.1016/j.ccr.2010.03.021
  • Herrero-Martin G, Hoyer-Hansen M, Garcia-Garcia C, Fumarola C, Farkas T, Lopez-Rivas A, Jaattela M. TAK1 activates AMPK-dependent cytoprotective autophagy in TRAIL-treated epithelial cells. EMBO J 2009; 28:677-685; PMID:19197243; http://dx.doi.org/10.1038/emboj.2009.8
  • Inokuchi-Shimizu S, Park EJ, Roh YS, Yang L, Zhang B, Song J, Liang S, Pimienta M, Taniguchi K, Wu X, et al. TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis. J Clin Invest 2014; 124:3566-3578; PMID:24983318; http://dx.doi.org/10.1172/JCI74068
  • Shin JH, Min SH, Kim SJ, Kim YI, Park J, Lee HK, Yoo OJ. TAK1 regulates autophagic cell death by suppressing the phosphorylation of p70 S6 kinase 1. Sci Rep 2013; 3:1561.
  • Criollo A, Senovilla L, Authier H, Maiuri MC, Morselli E, Vitale I, Kepp O, Tasdemir E, Galluzzi L, Shen S, et al. The IKK complex contributes to the induction of autophagy. EMBO J 2010;29:619-631; PMID:19959994; http://dx.doi.org/10.1038/emboj.2009.364
  • Sengupta S, Peterson TR, Laplante M, Oh S, Sabatini DM. mTORC1 controls fasting-induced ketogenesis and its modulation by ageing. Nature 2010;468:1100-1104; PMID:21179166; http://dx.doi.org/10.1038/nature09584
  • Ichimura Y, Waguri S, Sou YS, Kageyama S, Hasegawa J, Ishimura R, Saito T, Yang Y, Kouno T, Fukutomi T, et al. Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy. Mol Cell 2013;51:618-631; PMID:24011591; http://dx.doi.org/10.1016/j.molcel.2013.08.003