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Commentary

A possible secondary immune response in adipose tissue during weight cycling

The ups and downs of yo-yo dieting

, &
Pages 141-145 | Received 18 Nov 2013, Accepted 16 Dec 2013, Published online: 08 Jan 2014

References

  • Anderson EK, Gutierrez DA, Kennedy A, Hasty AH. Weight cycling increases T-cell accumulation in adipose tissue and impairs systemic glucose tolerance. Diabetes 2013; 62:3180 - 8; http://dx.doi.org/10.2337/db12-1076; PMID: 23733197
  • Mathis D, Shoelson SE. Immunometabolism: an emerging frontier. Nat Rev Immunol 2011; 11:81; http://dx.doi.org/10.1038/nri2922; PMID: 21469396
  • Xu H, Barnes GT, Yang Q, Tan G, Yang D, Chou CJ, Sole J, Nichols A, Ross JS, Tartaglia LA, et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 2003; 112:1821 - 30; PMID: 14679177
  • Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW Jr.. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 2003; 112:1796 - 808; PMID: 14679176
  • Elgazar-Carmon V, Rudich A, Hadad N, Levy R. Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding. J Lipid Res 2008; 49:1894 - 903; http://dx.doi.org/10.1194/jlr.M800132-JLR200; PMID: 18503031
  • Wu D, Molofsky AB, Liang HE, Ricardo-Gonzalez RR, Jouihan HA, Bando JK, Chawla A, Locksley RM. Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis. Science 2011; 332:243 - 7; http://dx.doi.org/10.1126/science.1201475; PMID: 21436399
  • Altintas MM, Rossetti MA, Nayer B, Puig A, Zagallo P, Ortega LM, Johnson KB, McNamara G, Reiser J, Mendez AJ, et al. Apoptosis, mastocytosis, and diminished adipocytokine gene expression accompany reduced epididymal fat mass in long-standing diet-induced obese mice. Lipids Health Dis 2011; 10:198; http://dx.doi.org/10.1186/1476-511X-10-198; PMID: 22051061
  • Surmi BK, Hasty AH. The role of chemokines in recruitment of immune cells to the artery wall and adipose tissue. Vascul Pharmacol 2010; 52:27 - 36; http://dx.doi.org/10.1016/j.vph.2009.12.004; PMID: 20026286
  • Poursharifi P, Lapointe M, Pétrin D, Devost D, Gauvreau D, Hébert TE, Cianflone K. C5L2 and C5aR interaction in adipocytes and macrophages: insights into adipoimmunology. Cell Signal 2013; 25:910 - 8; http://dx.doi.org/10.1016/j.cellsig.2012.12.010; PMID: 23268185
  • Cinti S, Mitchell G, Barbatelli G, Murano I, Ceresi E, Faloia E, Wang S, Fortier M, Greenberg AS, Obin MS. Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J Lipid Res 2005; 46:2347 - 55; http://dx.doi.org/10.1194/jlr.M500294-JLR200; PMID: 16150820
  • Winer S, Chan Y, Paltser G, Truong D, Tsui H, Bahrami J, Dorfman R, Wang Y, Zielenski J, Mastronardi F, et al. Normalization of obesity-associated insulin resistance through immunotherapy. Nat Med 2009; 15:921 - 9; http://dx.doi.org/10.1038/nm.2001; PMID: 19633657
  • Feuerer M, Herrero L, Cipolletta D, Naaz A, Wong J, Nayer A, Lee J, Goldfine AB, Benoist C, Shoelson S, et al. Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat Med 2009; 15:930 - 9; http://dx.doi.org/10.1038/nm.2002; PMID: 19633656
  • Nishimura S, Manabe I, Nagasaki M, Eto K, Yamashita H, Ohsugi M, Otsu M, Hara K, Ueki K, Sugiura S, et al. CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity. Nat Med 2009; 15:914 - 20; http://dx.doi.org/10.1038/nm.1964; PMID: 19633658
  • Winer DA, Winer S, Shen L, Wadia PP, Yantha J, Paltser G, Tsui H, Wu P, Davidson MG, Alonso MN, et al. B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies. Nat Med 2011; 17:610 - 7; http://dx.doi.org/10.1038/nm.2353; PMID: 21499269
  • Wu L, Parekh VV, Gabriel CL, Bracy DP, Marks-Shulman PA, Tamboli RA, Kim S, Mendez-Fernandez YV, Besra GS, Lomenick JP, et al. Activation of invariant natural killer T cells by lipid excess promotes tissue inflammation, insulin resistance, and hepatic steatosis in obese mice. Proc Natl Acad Sci U S A 2012; 109:E1143 - 52; http://dx.doi.org/10.1073/pnas.1200498109; PMID: 22493234
  • Yang H, Youm YH, Vandanmagsar B, Ravussin A, Gimble JM, Greenway F, Stephens JM, Mynatt RL, Dixit VD. Obesity increases the production of proinflammatory mediators from adipose tissue T cells and compromises TCR repertoire diversity: implications for systemic inflammation and insulin resistance. J Immunol 2010; 185:1836 - 45; http://dx.doi.org/10.4049/jimmunol.1000021; PMID: 20581149
  • Kosteli A, Sugaru E, Haemmerle G, Martin JF, Lei J, Zechner R, Ferrante AW Jr.. Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue. J Clin Invest 2010; 120:3466 - 79; http://dx.doi.org/10.1172/JCI42845; PMID: 20877011
  • Gregor MF, Yang L, Fabbrini E, Mohammed BS, Eagon JC, Hotamisligil GS, Klein S. Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss. Diabetes 2009; 58:693 - 700; http://dx.doi.org/10.2337/db08-1220; PMID: 19066313
  • Williamson DF, Serdula MK, Anda RF, Levy A, Byers T. Weight loss attempts in adults: goals, duration, and rate of weight loss. Am J Public Health 1992; 82:1251 - 7; http://dx.doi.org/10.2105/AJPH.82.9.1251; PMID: 1503167
  • Stevens VL, Jacobs EJ, Sun J, Patel AV, McCullough ML, Teras LR, Gapstur SM. Weight cycling and mortality in a large prospective US study. Am J Epidemiol 2012; 175:785 - 92; http://dx.doi.org/10.1093/aje/kwr378; PMID: 22287640
  • Schotte DE, Cohen E, Singh SP. Effects of weight cycling on metabolic control in male outpatients with non-insulin-dependent diabetes mellitus. Health Psychol 1990; 9:599 - 605; http://dx.doi.org/10.1037/0278-6133.9.5.599; PMID: 2226388
  • Jeffery RW, Wing RR, French SA. Weight cycling and cardiovascular risk factors in obese men and women. Am J Clin Nutr 1992; 55:641 - 4; PMID: 1550037
  • Li Z, Hong K, Wong E, Maxwell M, Heber D. Weight cycling in a very low-calorie diet programme has no effect on weight loss velocity, blood pressure and serum lipid profile. Diabetes Obes Metab 2007; 9:379 - 85; http://dx.doi.org/10.1111/j.1463-1326.2006.00621.x; PMID: 17391166
  • Hamm P, Shekelle RB, Stamler J. Large fluctuations in body weight during young adulthood and twenty-five-year risk of coronary death in men. Am J Epidemiol 1989; 129:312 - 8; PMID: 2912043
  • Waring ME, Eaton CB, Lasater TM, Lapane KL. Incident diabetes in relation to weight patterns during middle age. Am J Epidemiol 2010; 171:550 - 6; http://dx.doi.org/10.1093/aje/kwp433; PMID: 20110286
  • Olson MB, Kelsey SF, Bittner V, Reis SE, Reichek N, Handberg EM, Merz CN, Women’s Ischemia Syndrome Evaluation Study Group. Weight cycling and high-density lipoprotein cholesterol in women: evidence of an adverse effect: a report from the NHLBI-sponsored WISE study. J Am Coll Cardiol 2000; 36:1565 - 71; http://dx.doi.org/10.1016/S0735-1097(00)00901-3; PMID: 11079659
  • Kalia V, Sarkar S, Gourley TS, Rouse BT, Ahmed R. Differentiation of memory B and T cells. Curr Opin Immunol 2006; 18:255 - 64; http://dx.doi.org/10.1016/j.coi.2006.03.020; PMID: 16632337
  • Ojdana D, Safiejko K, Lipska A, Radziwon P, Dadan J, Tryniszewska E. Effector and memory CD4+ and CD8+ T cells in the chronic infection process. Folia Histochem Cytobiol 2008; 46:413 - 7; PMID: 19141390
  • Obar JJ, Lefrançois L. Memory CD8+ T cell differentiation. Ann N Y Acad Sci 2010; 1183:251 - 66; http://dx.doi.org/10.1111/j.1749-6632.2009.05126.x; PMID: 20146720
  • Beverley PC. Kinetics and clonality of immunological memory in humans. Semin Immunol 2004; 16:315 - 21; http://dx.doi.org/10.1016/j.smim.2004.08.012; PMID: 15528076
  • Duffaut C, Zakaroff-Girard A, Bourlier V, Decaunes P, Maumus M, Chiotasso P, Sengenès C, Lafontan M, Galitzky J, Bouloumié A. Interplay between human adipocytes and T lymphocytes in obesity: CCL20 as an adipochemokine and T lymphocytes as lipogenic modulators. Arterioscler Thromb Vasc Biol 2009; 29:1608 - 14; http://dx.doi.org/10.1161/ATVBAHA.109.192583; PMID: 19644053
  • Hansson GK, Hermansson A. The immune system in atherosclerosis. Nat Immunol 2011; 12:204 - 12; http://dx.doi.org/10.1038/ni.2001; PMID: 21321594
  • Morris DL, Cho KW, Delproposto JL, Oatmen KE, Geletka LM, Martinez-Santibanez G, Singer K, Lumeng CN. Adipose tissue macrophages function as antigen-presenting cells and regulate adipose tissue CD4+ T cells in mice. Diabetes 2013; 62:2762 - 72; http://dx.doi.org/10.2337/db12-1404; PMID: 23493569
  • Meijer K, de Vries M, Al-Lahham S, Bruinenberg M, Weening D, Dijkstra M, Kloosterhuis N, van der Leij RJ, van der Want H, Kroesen BJ, et al. Human primary adipocytes exhibit immune cell function: adipocytes prime inflammation independent of macrophages. PLoS One 2011; 6:e17154; http://dx.doi.org/10.1371/journal.pone.0017154; PMID: 21448265
  • Deng T, Lyon CJ, Minze LJ, Lin J, Zou J, Liu JZ, Ren Y, Yin Z, Hamilton DJ, Reardon PR, et al. Class II major histocompatibility complex plays an essential role in obesity-induced adipose inflammation. Cell Metab 2013; 17:411 - 22; http://dx.doi.org/10.1016/j.cmet.2013.02.009; PMID: 23473035
  • Parish IA, Heath WR. Too dangerous to ignore: self-tolerance and the control of ignorant autoreactive T cells. Immunol Cell Biol 2008; 86:146 - 52; http://dx.doi.org/10.1038/sj.icb.7100161; PMID: 18227854
  • Cipolletta D, Feuerer M, Li A, Kamei N, Lee J, Shoelson SE, Benoist C, Mathis D. PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells. Nature 2012; 486:549 - 53; PMID: 22722857
  • Yang H, Youm YH, Vandanmagsar B, Rood J, Kumar KG, Butler AA, Dixit VD. Obesity accelerates thymic aging. Blood 2009; 114:3803 - 12; http://dx.doi.org/10.1182/blood-2009-03-213595; PMID: 19721009
  • Dankel SN, Degerud EM, Borkowski K, Fjære E, Midtbø LK, Haugen C, Solsvik MH, Lavigne AM, Liaset B, Sagen JV, et al. Weight cycling promotes fat gain and altered clock gene expression in adipose tissue in C57BL/6J mice. Am J Physiol Endocrinol Metab 2013; Forthcoming http://dx.doi.org/10.1152/ajpendo.00188.2013; PMID: 24302006

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