1,545
Views
33
CrossRef citations to date
0
Altmetric
Basic Brief Report

Structural characterization of the Saccharomyces cerevisiae autophagy regulatory complex Atg17-Atg31-Atg29

, , &
Pages 1467-1474 | Received 19 Feb 2013, Accepted 09 Jul 2013, Published online: 05 Aug 2013

References

  • Nakatogawa H, Suzuki K, Kamada Y, Ohsumi Y. Dynamics and diversity in autophagy mechanisms: lessons from yeast. Nat Rev Mol Cell Biol 2009; 10:458 - 67; http://dx.doi.org/10.1038/nrm2708; PMID: 19491929
  • Kraft C, Martens S. Mechanisms and regulation of autophagosome formation. Curr Opin Cell Biol 2012; 24:496 - 501; http://dx.doi.org/10.1016/j.ceb.2012.05.001; PMID: 22664348
  • Noda NN, Ohsumi Y, Inagaki F. ATG systems from the protein structural point of view. Chem Rev 2009; 109:1587 - 98; http://dx.doi.org/10.1021/cr800459r; PMID: 19236009
  • Suzuki K, Ohsumi Y. Current knowledge of the pre-autophagosomal structure (PAS). FEBS Lett 2010; 584:1280 - 6; http://dx.doi.org/10.1016/j.febslet.2010.02.001; PMID: 20138172
  • Mizushima N, Yoshimori T, Ohsumi Y. The role of Atg proteins in autophagosome formation. Annu Rev Cell Dev Biol 2011; 27:107 - 32; http://dx.doi.org/10.1146/annurev-cellbio-092910-154005; PMID: 21801009
  • Suzuki K, Kubota Y, Sekito T, Ohsumi Y. Hierarchy of Atg proteins in pre-autophagosomal structure organization. Genes Cells 2007; 12:209 - 18; http://dx.doi.org/10.1111/j.1365-2443.2007.01050.x; PMID: 17295840
  • Cheong H, Yorimitsu T, Reggiori F, Legakis JE, Wang C-W, Klionsky DJ. Atg17 regulates the magnitude of the autophagic response. Mol Biol Cell 2005; 16:3438 - 53; http://dx.doi.org/10.1091/mbc.E04-10-0894; PMID: 15901835
  • Kabeya Y, Kamada Y, Baba M, Takikawa H, Sasaki M, Ohsumi Y. Atg17 functions in cooperation with Atg1 and Atg13 in yeast autophagy. Mol Biol Cell 2005; 16:2544 - 53; http://dx.doi.org/10.1091/mbc.E04-08-0669; PMID: 15743910
  • Kawamata T, Kamada Y, Kabeya Y, Sekito T, Ohsumi Y. Organization of the pre-autophagosomal structure responsible for autophagosome formation. Mol Biol Cell 2008; 19:2039 - 50; http://dx.doi.org/10.1091/mbc.E07-10-1048; PMID: 18287526
  • Kabeya Y, Noda NN, Fujioka Y, Suzuki K, Inagaki F, Ohsumi Y. Characterization of the Atg17-Atg29-Atg31 complex specifically required for starvation-induced autophagy in Saccharomyces cerevisiae.. Biochem Biophys Res Commun 2009; 389:612 - 5; http://dx.doi.org/10.1016/j.bbrc.2009.09.034; PMID: 19755117
  • Kraft C, Kijanska M, Kalie E, Siergiejuk E, Lee SS, Semplicio G, Stoffel I, Brezovich A, Verma M, Hansmann I, et al. Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy. EMBO J 2012; 31:3691 - 703; http://dx.doi.org/10.1038/emboj.2012.225; PMID: 22885598
  • Kamada Y, Funakoshi T, Shintani T, Nagano K, Ohsumi M, Ohsumi Y. Tor-mediated induction of autophagy via an Apg1 protein kinase complex. J Cell Biol 2000; 150:1507 - 13; http://dx.doi.org/10.1083/jcb.150.6.1507; PMID: 10995454
  • Ragusa MJ, Stanley RE, Hurley JH. Architecture of the Atg17 complex as a scaffold for autophagosome biogenesis. Cell 2012; 151:1501 - 12; http://dx.doi.org/10.1016/j.cell.2012.11.028; PMID: 23219485
  • Rigaut G, Shevchenko A, Rutz B, Wilm M, Mann M, Séraphin B. A generic protein purification method for protein complex characterization and proteome exploration. Nat Biotechnol 1999; 17:1030 - 2; http://dx.doi.org/10.1038/13732; PMID: 10504710
  • Puig O, Caspary F, Rigaut G, Rutz B, Bouveret E, Bragado-Nilsson E, Wilm M, Séraphin B. The tandem affinity purification (TAP) method: a general procedure of protein complex purification. Methods 2001; 24:218 - 29; http://dx.doi.org/10.1006/meth.2001.1183; PMID: 11403571
  • Ghaemmaghami S, Huh WK, Bower K, Howson RW, Belle A, Dephoure N, O’Shea EK, Weissman JS. Global analysis of protein expression in yeast. Nature 2003; 425:737 - 41; http://dx.doi.org/10.1038/nature02046; PMID: 14562106
  • Yip CK, Walz T. Molecular structure and flexibility of the yeast coatomer as revealed by electron microscopy. J Mol Biol 2011; 408:825 - 31; http://dx.doi.org/10.1016/j.jmb.2011.03.029; PMID: 21435344
  • Ohi M, Li Y, Cheng Y, Walz T. Negative Staining and Image Classification - Powerful Tools in Modern Electron Microscopy. Biol Proced Online 2004; 6:23 - 34; http://dx.doi.org/10.1251/bpo70; PMID: 15103397
  • Radermacher M, Wagenknecht T, Verschoor A, Frank J. Three-dimensional reconstruction from a single-exposure, random conical tilt series applied to the 50S ribosomal subunit of Escherichia coli.. J Microsc 1987; 146:113 - 36; http://dx.doi.org/10.1111/j.1365-2818.1987.tb01333.x; PMID: 3302267
  • Frank J, Radermacher M, Penczek P, Zhu J, Li Y, Ladjadj M, Leith A. SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields. J Struct Biol 1996; 116:190 - 9; http://dx.doi.org/10.1006/jsbi.1996.0030; PMID: 8742743
  • Lees JA, Yip CK, Walz T, Hughson FM. Molecular organization of the COG vesicle tethering complex. Nat Struct Mol Biol 2010; 17:1292 - 7; http://dx.doi.org/10.1038/nsmb.1917; PMID: 20972446
  • Mao K, Chew LH, Inoue-Aono Y, Cheong H, Nair U, Popelka H, Yip CK, Klionsky DJ. Atg29 phosphorylation regulates coordination of the Atg17-Atg31-Atg29 complex with the Atg11 scaffold during autophagy initiation. Proc Natl Acad Sci U S A 2013; 110:E2875 - 84; http://dx.doi.org/10.1073/pnas.1300064110; PMID: 23858448
  • Hara T, Mizushima N. Role of ULK-FIP200 complex in mammalian autophagy: FIP200, a counterpart of yeast Atg17?. Autophagy 2009; 5:85 - 7; http://dx.doi.org/10.4161/auto.5.1.7180; PMID: 18981720
  • Kawamata T, Kamada Y, Suzuki K, Kuboshima N, Akimatsu H, Ota S, Ohsumi M, Ohsumi Y. Characterization of a novel autophagy-specific gene, ATG29. Biochem Biophys Res Commun 2005; 338:1884 - 9; http://dx.doi.org/10.1016/j.bbrc.2005.10.163; PMID: 16289106
  • Kabeya Y, Kawamata T, Suzuki K, Ohsumi Y. Cis1/Atg31 is required for autophagosome formation in Saccharomyces cerevisiae.. Biochem Biophys Res Commun 2007; 356:405 - 10; http://dx.doi.org/10.1016/j.bbrc.2007.02.150; PMID: 17362880
  • Qualmann B, Koch D, Kessels MM. Let’s go bananas: revisiting the endocytic BAR code. EMBO J 2011; 30:3501 - 15; http://dx.doi.org/10.1038/emboj.2011.266; PMID: 21878992
  • Van Petegem F, Clark KA, Chatelain FC, Minor DL Jr.. Structure of a complex between a voltage-gated calcium channel beta-subunit and an alpha-subunit domain. Nature 2004; 429:671 - 5; http://dx.doi.org/10.1038/nature02588; PMID: 15141227
  • Ludtke SJ, Baldwin PR, Chiu W. EMAN: semiautomated software for high-resolution single-particle reconstructions. J Struct Biol 1999; 128:82 - 97; http://dx.doi.org/10.1006/jsbi.1999.4174; PMID: 10600563

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.