Oxygen levels and the regulation of cell adhesion in the nervous system

References

• Lendahl U, Lee KL, Yang H, Poellinger L. Generating specificity and diversity in the transcriptional response to hypoxia. Nat Rev Genet 2009; 10:821 - 32; http://dx.doi.org/10.1038/nrg2665; PMID: 19884889
   PubMed Web of Science ®Google Scholar
• Kaelin WG Jr., Ratcliffe PJ. Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway. Mol Cell 2008; 30:393 - 402; http://dx.doi.org/10.1016/j.molcel.2008.04.009; PMID: 18498744
   PubMed Web of Science ®Google Scholar
• Kaelin WG Jr. The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer. Nat Rev Cancer 2008; 8:865 - 73; http://dx.doi.org/10.1038/nrc2502; PMID: 18923434
   PubMed Web of Science ®Google Scholar
• Majmundar AJ, Wong WJ, Simon MC. Hypoxia-inducible factors and the response to hypoxic stress. Mol Cell 2010; 40:294 - 309; http://dx.doi.org/10.1016/j.molcel.2010.09.022; PMID: 20965423
   PubMed Web of Science ®Google Scholar
• Webster KA. Evolution of the coordinate regulation of glycolytic enzyme genes by hypoxia. J Exp Biol 2003; 206:2911 - 22; http://dx.doi.org/10.1242/jeb.00516; PMID: 12878660
   PubMed Web of Science ®Google Scholar
• Papandreou I, Cairns RA, Fontana L, Lim AL, Denko NC. HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption. Cell Metab 2006; 3:187 - 97; http://dx.doi.org/10.1016/j.cmet.2006.01.012; PMID: 16517406
   PubMed Web of Science ®Google Scholar
• Mazumdar J, Dondeti V, Simon MC. Hypoxia-inducible factors in stem cells and cancer. J Cell Mol Med 2009; 13:4319 - 28; http://dx.doi.org/10.1111/j.1582-4934.2009.00963.x; PMID: 19900215
   PubMed Web of Science ®Google Scholar
• Jiang BH, Semenza GL, Bauer C, Marti HH. Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension. Am J Physiol 1996; 271:C1172 - 80; PMID: 8897823
   PubMed Web of Science ®Google Scholar
• Spellman PT, Sherlock G, Zhang MQ, Iyer VR, Anders K, Eisen MB, et al. Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization. Mol Biol Cell 1998; 9:3273 - 97; PMID: 9843569
   PubMed Web of Science ®Google Scholar
• Morriss GM, New DA. Effect of oxygen concentration on morphogenesis of cranial neural folds and neural crest in cultured rat embryos. J Embryol Exp Morphol 1979; 54:17 - 35; PMID: 528863
   PubMedGoogle Scholar
• Ivanovic Z. Hypoxia or in situ normoxia: The stem cell paradigm. J Cell Physiol 2009; 219:271 - 5; http://dx.doi.org/10.1002/jcp.21690; PMID: 19160417
   PubMed Web of Science ®Google Scholar
• Simon MC, Keith B. The role of oxygen availability in embryonic development and stem cell function. Nat Rev Mol Cell Biol 2008; 9:285 - 96; http://dx.doi.org/10.1038/nrm2354; PMID: 18285802
   PubMed Web of Science ®Google Scholar
• Panchision DM. The role of oxygen in regulating neural stem cells in development and disease. J Cell Physiol 2009; 220:562 - 8; http://dx.doi.org/10.1002/jcp.21812; PMID: 19441077
   PubMed Web of Science ®Google Scholar
• Studer L, Csete M, Lee SH, Kabbani N, Walikonis J, Wold B, et al. Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in lowered oxygen. J Neurosci 2000; 20:7377 - 83; PMID: 11007896
   PubMed Web of Science ®Google Scholar
• Tsatmali M, Walcott EC, Crossin KL. Newborn neurons acquire high levels of reactive oxygen species and increased mitochondrial proteins upon differentiation from progenitors. Brain Res 2005; 1040:137 - 50; http://dx.doi.org/10.1016/j.brainres.2005.01.087; PMID: 15804435
   PubMed Web of Science ®Google Scholar
• Chen HL, Pistollato F, Hoeppner DJ, Ni HT, McKay RD, Panchision DM. Oxygen tension regulates survival and fate of mouse central nervous system precursors at multiple levels. Stem Cells 2007; 25:2291 - 301; http://dx.doi.org/10.1634/stemcells.2006-0609; PMID: 17556599
   PubMed Web of Science ®Google Scholar
• Milosevic J, Adler I, Manaenko A, Schwarz SC, Walkinshaw G, Arend M, et al. Non-hypoxic stabilization of hypoxia-inducible factor alpha (HIF-alpha): relevance in neural progenitor/stem cells. Neurotox Res 2009; 15:367 - 80; http://dx.doi.org/10.1007/s12640-009-9043-z; PMID: 19384570
   PubMed Web of Science ®Google Scholar
• Zhou L, Miller CA. Mitogen-activated protein kinase signaling, oxygen sensors and hypoxic induction of neurogenesis. Neurodegener Dis 2006; 3:50 - 5; http://dx.doi.org/10.1159/000092093; PMID: 16909037
   PubMed Web of Science ®Google Scholar
• Pistollato F, Chen HL, Schwartz PH, Basso G, Panchision DM. Oxygen tension controls the expansion of human CNS precursors and the generation of astrocytes and oligodendrocytes. Mol Cell Neurosci 2007; 35:424 - 35; http://dx.doi.org/10.1016/j.mcn.2007.04.003; PMID: 17498968
   PubMed Web of Science ®Google Scholar
• Horie N, So K, Moriya T, Kitagawa N, Tsutsumi K, Nagata I, et al. Effects of oxygen concentration on the proliferation and differentiation of mouse neural stem cells in vitro. Cell Mol Neurobiol 2008; 28:833 - 45; http://dx.doi.org/10.1007/s10571-007-9237-y; PMID: 18236013
   PubMed Web of Science ®Google Scholar
• Zhao T, Zhang CP, Liu ZH, Wu LY, Huang X, Wu HT, et al. Hypoxia-driven proliferation of embryonic neural stem/progenitor cells--role of hypoxia-inducible transcription factor-1alpha. FEBS J 2008; 275:1824 - 34; http://dx.doi.org/10.1111/j.1742-4658.2008.06340.x; PMID: 18341590
   PubMed Web of Science ®Google Scholar
• Mazumdar J, O’Brien WT, Johnson RS, LaManna JC, Chavez JC, Klein PS, et al. O2 regulates stem cells through Wnt/β-catenin signalling. Nat Cell Biol 2010; 12:1007 - 13; http://dx.doi.org/10.1038/ncb2102; PMID: 20852629
   PubMed Web of Science ®Google Scholar
• Ingraham CA, Park GC, Makarenkova HP, Crossin KL. Matrix metalloproteinase (MMP)-9 induced by Wnt signaling increases the proliferation and migration of embryonic neural stem cells at low O2 levels. J Biol Chem 2011; 286:17649 - 57; http://dx.doi.org/10.1074/jbc.M111.229427; PMID: 21460212
   PubMed Web of Science ®Google Scholar
• Morrison SJ, Csete M, Groves AK, Melega W, Wold B, Anderson DJ. Culture in reduced levels of oxygen promotes clonogenic sympathoadrenal differentiation by isolated neural crest stem cells. J Neurosci 2000; 20:7370 - 6; PMID: 11007895
   PubMed Web of Science ®Google Scholar
• Zhang CP, Zhu LL, Zhao T, Zhao H, Huang X, Ma X, et al. Characteristics of neural stem cells expanded in lowered oxygen and the potential role of hypoxia-inducible factor-1Alpha. Neurosignals 2006-2007; 15:259 - 65; http://dx.doi.org/10.1159/000103385; PMID: 17551265
   PubMed Web of Science ®Google Scholar
• Krabbe C, Courtois E, Jensen P, Jørgensen JR, Zimmer J, Marti´nez-Serrano A, et al. Enhanced dopaminergic differentiation of human neural stem cells by synergistic effect of Bcl-xL and reduced oxygen tension. J Neurochem 2009; 110:1908 - 20; http://dx.doi.org/10.1111/j.1471-4159.2009.06281.x; PMID: 19627448
   PubMed Web of Science ®Google Scholar
• Millman JR, Tan JH, Colton CK. The effects of low oxygen on self-renewal and differentiation of embryonic stem cells. Curr Opin Organ Transplant 2009; 14:694 - 700; http://dx.doi.org/10.1097/MOT.0b013e3283329d53; PMID: 19779343
   PubMed Web of Science ®Google Scholar
• Harms KM, Li L, Cunningham LA. Murine neural stem/progenitor cells protect neurons against ischemia by HIF-1alpha-regulated VEGF signaling. PLoS One 2010; 5:e9767; http://dx.doi.org/10.1371/journal.pone.0009767; PMID: 20339541
   PubMedGoogle Scholar
• Santilli G, Lamorte G, Carlessi L, Ferrari D, Rota Nodari L, Binda E, et al. Mild hypoxia enhances proliferation and multipotency of human neural stem cells. PLoS One 2010; 5:e8575; http://dx.doi.org/10.1371/journal.pone.0008575; PMID: 20052410
   PubMed Web of Science ®Google Scholar
• Yoshida Y, Takahashi K, Okita K, Ichisaka T, Yamanaka S. Hypoxia enhances the generation of induced pluripotent stem cells. Cell Stem Cell 2009; 5:237 - 41; http://dx.doi.org/10.1016/j.stem.2009.08.001; PMID: 19716359
   PubMed Web of Science ®Google Scholar
• Clarke L, van der Kooy D. Low oxygen enhances primitive and definitive neural stem cell colony formation by inhibiting distinct cell death pathways. Stem Cells 2009; 27:1879 - 86; http://dx.doi.org/10.1002/stem.96; PMID: 19544448
   PubMed Web of Science ®Google Scholar
• Lin Q, Kim Y, Alarcon RM, Yun Z. Oxygen and Cell Fate Decisions. Gene Regul Syst Bio 2008; 2:43 - 51; PMID: 19606268
   PubMedGoogle Scholar
• Dirken MN, Heemstra H. Alveolar oxygen tension and lung circulation. Q J Exp Physiol 1948; 34:193 - 211; PMID: 18111539
   PubMed Web of Science ®Google Scholar
• Horng CT, Liu CC, Wu DM, Wu YC, Chen JT, Chang CJ, et al. Visual fields during acute exposure to a simulated altitude of 7620 m. Aviat Space Environ Med 2008; 79:666 - 9; http://dx.doi.org/10.3357/ASEM.2160.2008; PMID: 18619125
   PubMed Web of Science ®Google Scholar
• Erecińska M, Silver IA. Tissue oxygen tension and brain sensitivity to hypoxia. Respir Physiol 2001; 128:263 - 76; http://dx.doi.org/10.1016/S0034-5687(01)00306-1; PMID: 11718758
   PubMedGoogle Scholar
• Hoffman CE, Clark RT Jr., Brown EB Jr. Blood oxygen saturations and duration of consciousness in anoxia at high altitudes. Am J Physiol 1946; 145:685 - 92; PMID: 21021848
   PubMed Web of Science ®Google Scholar
• Vieira HL, Alves PM, Vercelli A. Modulation of neuronal stem cell differentiation by hypoxia and reactive oxygen species. Prog Neurobiol 2011; 93:444 - 55; http://dx.doi.org/10.1016/j.pneurobio.2011.01.007; PMID: 21251953
   PubMed Web of Science ®Google Scholar
• Skloot R. The Immortal Life of Henrietta Lacks. Crown, 2010.
   Google Scholar
• Crossin KL. Cell adhesion molecules in embryogenesis and disease. Ann N Y Acad Sci 1991; 615:172 - 86; http://dx.doi.org/10.1111/j.1749-6632.1991.tb37759.x; PMID: 2039143
   PubMedGoogle Scholar
• Edelman GM, Crossin KL. Cell adhesion molecules: implications for a molecular histology. Annu Rev Biochem 1991; 60:155 - 90; http://dx.doi.org/10.1146/annurev.bi.60.070191.001103; PMID: 1883195
   PubMed Web of Science ®Google Scholar
• Zhu LL, Zhao T, huang X, Liu ZH, Wu LY, Wu KW, et al. Gene expression profiles and metabolic changes in embryonic neural progenitor cells under low oxygen. Cell Reprogram 2011; 13:113 - 20; http://dx.doi.org/10.1089/cell.2010.0043; PMID: 21473688
   PubMed Web of Science ®Google Scholar
• Song SW, Chang W, Song BW, Song H, Lim S, Kim HJ, et al. Integrin-linked kinase is required in hypoxic mesenchymal stem cells for strengthening cell adhesion to ischemic myocardium. Stem Cells 2009; 27:1358 - 65; http://dx.doi.org/10.1002/stem.47; PMID: 19489098
   PubMed Web of Science ®Google Scholar
• Grayson WL, Zhao F, Bunnell B, Ma T. Hypoxia enhances proliferation and tissue formation of human mesenchymal stem cells. Biochem Biophys Res Commun 2007; 358:948 - 53; http://dx.doi.org/10.1016/j.bbrc.2007.05.054; PMID: 17521616
   PubMed Web of Science ®Google Scholar
• Cowden Dahl KD, Robertson SE, Weaver VM, Simon MC. Hypoxia-inducible factor regulates alphavbeta3 integrin cell surface expression. Mol Biol Cell 2005; 16:1901 - 12; http://dx.doi.org/10.1091/mbc.E04-12-1082; PMID: 15689487
   PubMed Web of Science ®Google Scholar
• Lekli I, Gurusamy N, Ray D, Tosaki A, Das DK. Redox regulation of stem cell mobilization. Can J Physiol Pharmacol 2009; 87:989 - 95; http://dx.doi.org/10.1139/Y09-102; PMID: 20029535
   PubMed Web of Science ®Google Scholar
• Mohyeldin A, Garzón-Muvdi T, Quiñones-Hinojosa A. Oxygen in stem cell biology: a critical component of the stem cell niche. Cell Stem Cell 2010; 7:150 - 61; http://dx.doi.org/10.1016/j.stem.2010.07.007; PMID: 20682444
   PubMed Web of Science ®Google Scholar
• Harrison JF, Haddad GG. Effects of oxygen on growth and size: synthesis of molecular, organismal, and evolutionary studies with Drosophila melanogaster. Annu Rev Physiol 2011; 73:95 - 113; http://dx.doi.org/10.1146/annurev-physiol-012110-142155; PMID: 20936942
   PubMed Web of Science ®Google Scholar
• Wu B, Crampton SP, Hughes CC. Wnt signaling induces matrix metalloproteinase expression and regulates T cell transmigration. Immunity 2007; 26:227 - 39; http://dx.doi.org/10.1016/j.immuni.2006.12.007; PMID: 17306568
   PubMed Web of Science ®Google Scholar
• Barker N. The canonical Wnt/beta-catenin signalling pathway. Methods Mol Biol 2008; 468:5 - 15; http://dx.doi.org/10.1007/978-1-59745-249-6_1; PMID: 19099242
   PubMedGoogle Scholar
• Nelson WJ, Nusse R. Convergence of Wnt, beta-catenin, and cadherin pathways. Science 2004; 303:1483 - 7; http://dx.doi.org/10.1126/science.1094291; PMID: 15001769
   PubMed Web of Science ®Google Scholar
• Jones FS, Jing J, Stonehouse AH, Stevens A, Edelman GM. Caffeine stimulates cytochrome oxidase expression and activity in the striatum in a sexually dimorphic manner. Mol Pharmacol 2008; 74:673 - 84; http://dx.doi.org/10.1124/mol.108.046888; PMID: 18583456
   PubMed Web of Science ®Google Scholar
• Eisenmann DM. Wnt signaling. WormBook 2005; 1 - 17; PMID: 18050402
   PubMedGoogle Scholar
• Cadigan KM, Peifer M. Wnt signaling from development to disease: insights from model systems. Cold Spring Harb Perspect Biol 2009; 1:a002881; http://dx.doi.org/10.1101/cshperspect.a002881; PMID: 20066091
   PubMed Web of Science ®Google Scholar
• Heuberger J, Birchmeier W. Interplay of cadherin-mediated cell adhesion and canonical Wnt signaling. Cold Spring Harb Perspect Biol 2010; 2:a002915; http://dx.doi.org/10.1101/cshperspect.a002915; PMID: 20182623
   PubMed Web of Science ®Google Scholar
• Sylvie J, Ellen C, Kris V. The role of Wnt in cell signaling and cell adhesion during early vertebrate development. Front Biosci 2012; 17:2352 - 66; PMID: 21622181
   PubMedGoogle Scholar
• Wu KJ, Yang MH. Epithelial-mesenchymal transition and cancer stemness: the Twist1-Bmi1 connection. Biosci Rep 2011; 31:449 - 55; PMID: 21919891
   PubMed Web of Science ®Google Scholar
• Saburi S, McNeill H. Organising cells into tissues: new roles for cell adhesion molecules in planar cell polarity. Curr Opin Cell Biol 2005; 17:482 - 8; http://dx.doi.org/10.1016/j.ceb.2005.08.011; PMID: 16099635
   PubMed Web of Science ®Google Scholar
• Wada H, Okamoto H. Roles of noncanonical Wnt/PCP pathway genes in neuronal migration and neurulation in zebrafish. Zebrafish 2009; 6:3 - 8; http://dx.doi.org/10.1089/zeb.2008.0557; PMID: 19250033
   PubMed Web of Science ®Google Scholar
• Devlin C, Greco S, Martelli F, Ivan M. miR-210: More than a silent player in hypoxia. IUBMB Life 2011; 63:94 - 100; PMID: 21360638
   PubMed Web of Science ®Google Scholar
• Huang S, He X. microRNAs: tiny RNA molecules, huge driving forces to move the cell. Protein Cell 2010; 1:916 - 26; http://dx.doi.org/10.1007/s13238-010-0116-9; PMID: 21204018
   PubMedGoogle Scholar
• McCormick R, Buffa FM, Ragoussis J, Harris AL. The role of hypoxia regulated microRNAs in cancer. Curr Top Microbiol Immunol 2010; 345:47 - 70; http://dx.doi.org/10.1007/82_2010_76; PMID: 20549470
   PubMed Web of Science ®Google Scholar
• Crosby ME, Devlin CM, Glazer PM, Calin GA, Ivan M. Emerging roles of microRNAs in the molecular responses to hypoxia. Curr Pharm Des 2009; 15:3861 - 6; http://dx.doi.org/10.2174/138161209789649367; PMID: 19925433
   PubMed Web of Science ®Google Scholar
• Dalmay T, Edwards DR. MicroRNAs and the hallmarks of cancer. Oncogene 2006; 25:6170 - 5; http://dx.doi.org/10.1038/sj.onc.1209911; PMID: 17028596
   PubMed Web of Science ®Google Scholar
• Pocock R. Invited review: decoding the microRNA response to hypoxia. Pflugers Arch 2011; 461:307 - 15; http://dx.doi.org/10.1007/s00424-010-0910-5; PMID: 21207057
   PubMed Web of Science ®Google Scholar
• Schliekelman MJ, Gibbons DL, Faca VM, Creighton CJ, Rizvi ZH, Zhang Q, et al. Targets of the tumor suppressor miR-200 in regulation of the epithelial-mesenchymal transition in cancer. Cancer Res 2011; 71:7670 - 82; http://dx.doi.org/10.1158/0008-5472.CAN-11-0964; PMID: 21987723
   PubMed Web of Science ®Google Scholar
• Abedin M, King N. Diverse evolutionary paths to cell adhesion. Trends Cell Biol 2010; 20:734 - 42; http://dx.doi.org/10.1016/j.tcb.2010.08.002; PMID: 20817460
   PubMed Web of Science ®Google Scholar
• Kirk DL. A twelve-step program for evolving multicellularity and a division of labor. Bioessays 2005; 27:299 - 310; http://dx.doi.org/10.1002/bies.20197; PMID: 15714559
   PubMed Web of Science ®Google Scholar
• James JL, Stone PR, Chamley LW. The regulation of trophoblast differentiation by oxygen in the first trimester of pregnancy. Hum Reprod Update 2006; 12:137 - 44; http://dx.doi.org/10.1093/humupd/dmi043; PMID: 16234296
   PubMed Web of Science ®Google Scholar
• Pringle KG, Kind KL, Sferruzzi-Perri AN, Thompson JG, Roberts CT. Beyond oxygen: complex regulation and activity of hypoxia inducible factors in pregnancy. Hum Reprod Update 2010; 16:415 - 31; http://dx.doi.org/10.1093/humupd/dmp046; PMID: 19926662
   PubMed Web of Science ®Google Scholar
• Tuuli MG, Longtine MS, Nelson DM. Review: Oxygen and trophoblast biology--a source of controversy. Placenta 2011; 32:Suppl 2 S109 - 18; http://dx.doi.org/10.1016/j.placenta.2010.12.013; PMID: 21216006
   PubMed Web of Science ®Google Scholar
• Golan MH, Mane R, Molczadzki G, Zuckerman M, Kaplan-Louson V, Huleihel M, et al. Impaired migration signaling in the hippocampus following prenatal hypoxia. Neuropharmacology 2009; 57:511 - 22; http://dx.doi.org/10.1016/j.neuropharm.2009.07.028; PMID: 19635490
   PubMed Web of Science ®Google Scholar
• Lee YM, Jeong CH, Koo SY, Son MJ, Song HS, Bae SK, et al. Determination of hypoxic region by hypoxia marker in developing mouse embryos in vivo: a possible signal for vessel development. Dev Dyn 2001; 220:175 - 86; http://dx.doi.org/10.1002/1097-0177(20010201)220:2<175::AID-DVDY1101>3.0.CO;2-F; PMID: 11169851
   PubMed Web of Science ®Google Scholar
• Slevin M, Krupinski J, Rovira N, Turu M, Luque A, Baldellou M, et al. Identification of pro-angiogenic markers in blood vessels from stroked-affected brain tissue using laser-capture microdissection. BMC Genomics 2009; 10:113; http://dx.doi.org/10.1186/1471-2164-10-113; PMID: 19292924
   PubMed Web of Science ®Google Scholar
• Li L, Liu F, Welser-Alves JV, McCullough LD, Milner R. Upregulation of fibronectin and the alpha5beta1 and alphavbeta3 integrins on blood vessels within the cerebral ischemic penumbra. Exp Neurol 2012; 233:283 - 91; http://dx.doi.org/10.1016/j.expneurol.2011.10.017; PMID: 22056225
   PubMed Web of Science ®Google Scholar
• Li L, Welser JV, Dore-Duffy P, del Zoppo GJ, Lamanna JC, Milner R. In the hypoxic central nervous system, endothelial cell proliferation is followed by astrocyte activation, proliferation, and increased expression of the alpha 6 beta 4 integrin and dystroglycan. Glia 2010; 58:1157 - 67; http://dx.doi.org/10.1002/glia.20995; PMID: 20544851
   PubMed Web of Science ®Google Scholar
• Abbruscato TJ, Davis TP. Protein expression of brain endothelial cell E-cadherin after hypoxia/aglycemia: influence of astrocyte contact. Brain Res 1999; 842:277 - 86; http://dx.doi.org/10.1016/S0006-8993(99)01778-3; PMID: 10526124
   PubMed Web of Science ®Google Scholar
• Doetsch F, Caille´ I, Lim DA, Garci´a-Verdugo JM, Alvarez-Buylla A. Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell 1999; 97:703 - 16; http://dx.doi.org/10.1016/S0092-8674(00)80783-7; PMID: 10380923
   PubMed Web of Science ®Google Scholar
• Cremer H, Lange R, Christoph A, Plomann M, Vopper G, Roes J, et al. Inactivation of the N-CAM gene in mice results in size reduction of the olfactory bulb and deficits in spatial learning. Nature 1994; 367:455 - 9; http://dx.doi.org/10.1038/367455a0; PMID: 8107803
   PubMed Web of Science ®Google Scholar
• Ono K, Tomasiewicz H, Magnuson T, Rutishauser U. N-CAM mutation inhibits tangential neuronal migration and is phenocopied by enzymatic removal of polysialic acid. Neuron 1994; 13:595 - 609; http://dx.doi.org/10.1016/0896-6273(94)90028-0; PMID: 7917293
   PubMed Web of Science ®Google Scholar
• Nait-Oumesmar B, Decker L, Lachapelle F, Avellana-Adalid V, Bachelin C, Van Evercooren AB. Progenitor cells of the adult mouse subventricular zone proliferate, migrate and differentiate into oligodendrocytes after demyelination. Eur J Neurosci 1999; 11:4357 - 66; http://dx.doi.org/10.1046/j.1460-9568.1999.00873.x; PMID: 10594662
   PubMed Web of Science ®Google Scholar
• Decker L, Durbec P, Rougon G, Evercooren AB. Loss of polysialic residues accelerates CNS neural precursor differentiation in pathological conditions. Mol Cell Neurosci 2002; 19:225 - 38; http://dx.doi.org/10.1006/mcne.2001.1072; PMID: 11860275
   PubMed Web of Science ®Google Scholar
• Keirstead HS, Ben-Hur T, Rogister B, O’Leary MT, Dubois-Dalcq M, Blakemore WF. Polysialylated neural cell adhesion molecule-positive CNS precursors generate both oligodendrocytes and Schwann cells to remyelinate the CNS after transplantation. J Neurosci 1999; 19:7529 - 36; PMID: 10460259
   PubMed Web of Science ®Google Scholar
• Courtès S, Vernerey J, Pujadas L, Magalon K, Cremer H, Soriano E, et al. Reelin controls progenitor cell migration in the healthy and pathological adult mouse brain. PLoS One 2011; 6:e20430; http://dx.doi.org/10.1371/journal.pone.0020430; PMID: 21647369
   PubMedGoogle Scholar
• Chen J, Bernreuther C, Dihne´ M, Schachner M. Cell adhesion molecule l1-transfected embryonic stem cells with enhanced survival support regrowth of corticospinal tract axons in mice after spinal cord injury. J Neurotrauma 2005; 22:896 - 906; http://dx.doi.org/10.1089/neu.2005.22.896; PMID: 16083356
   PubMed Web of Science ®Google Scholar
• Cui YF, Xu JC, Hargus G, Jakovcevski I, Schachner M, Bernreuther C. Embryonic stem cell-derived L1 overexpressing neural aggregates enhance recovery after spinal cord injury in mice. PLoS One 2011; 6:e17126; http://dx.doi.org/10.1371/journal.pone.0017126; PMID: 21445247
   PubMed Web of Science ®Google Scholar
• Bernreuther C, Dihne´ M, Johann V, Schiefer J, Cui Y, Hargus G, et al. Neural cell adhesion molecule L1-transfected embryonic stem cells promote functional recovery after excitotoxic lesion of the mouse striatum. J Neurosci 2006; 26:11532 - 9; http://dx.doi.org/10.1523/JNEUROSCI.2688-06.2006; PMID: 17093074
   PubMed Web of Science ®Google Scholar
• Liauw J, Hoang S, Choi M, Eroglu C, Choi M, Sun GH, et al. Thrombospondins 1 and 2 are necessary for synaptic plasticity and functional recovery after stroke. J Cereb Blood Flow Metab 2008; 28:1722 - 32; http://dx.doi.org/10.1038/jcbfm.2008.65; PMID: 18594557
   PubMed Web of Science ®Google Scholar
• Guzman R, De Los Angeles A, Cheshier S, Choi R, Hoang S, Liauw J, et al. Intracarotid injection of fluorescence activated cell-sorted CD49d-positive neural stem cells improves targeted cell delivery and behavior after stroke in a mouse stroke model. Stroke 2008; 39:1300 - 6; http://dx.doi.org/10.1161/STROKEAHA.107.500470; PMID: 18309158
   PubMed Web of Science ®Google Scholar
• Li D, Zhou J, Chowdhury F, Cheng J, Wang N, Wang F. Role of mechanical factors in fate decisions of stem cells. Regen Med 2011; 6:229 - 40; http://dx.doi.org/10.2217/rme.11.2; PMID: 21391856
   PubMed Web of Science ®Google Scholar
• Doetsch F. A niche for adult neural stem cells. Curr Opin Genet Dev 2003; 13:543 - 50; http://dx.doi.org/10.1016/j.gde.2003.08.012; PMID: 14550422
   PubMed Web of Science ®Google Scholar
• Shen Q, Goderie SK, Jin L, Karanth N, Sun Y, Abramova N, et al. Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells. Science 2004; 304:1338 - 40; http://dx.doi.org/10.1126/science.1095505; PMID: 15060285
   PubMed Web of Science ®Google Scholar
• Barami K. Relationship of neural stem cells with their vascular niche: implications in the malignant progression of gliomas. J Clin Neurosci 2008; 15:1193 - 7; http://dx.doi.org/10.1016/j.jocn.2008.01.002; PMID: 18617407
   PubMed Web of Science ®Google Scholar
• Huang Z, Cheng L, Guryanova OA, Wu Q, Bao S. Cancer stem cells in glioblastoma--molecular signaling and therapeutic targeting. Protein Cell 2010; 1:638 - 55; http://dx.doi.org/10.1007/s13238-010-0078-y; PMID: 21203936
   PubMed Web of Science ®Google Scholar
• Bar EE. Glioblastoma, cancer stem cells and hypoxia. Brain Pathol 2011; 21:119 - 29; http://dx.doi.org/10.1111/j.1750-3639.2010.00460.x; PMID: 21054626
   PubMed Web of Science ®Google Scholar
• Westphal M, Lamszus K. The neurobiology of gliomas: from cell biology to the development of therapeutic approaches. Nat Rev Neurosci 2011; 12:495 - 508; http://dx.doi.org/10.1038/nrn3060; PMID: 21811295
   PubMed Web of Science ®Google Scholar
• Wouters BG, Koritzinsky M. Hypoxia signalling through mTOR and the unfolded protein response in cancer. Nat Rev Cancer 2008; 8:851 - 64; http://dx.doi.org/10.1038/nrc2501; PMID: 18846101
   PubMed Web of Science ®Google Scholar
• Bernhard EJ. Interventions that induce modifications in the tumor microenvironment. Cancer Radiother 2011; 15:376 - 82; http://dx.doi.org/10.1016/j.canrad.2011.01.007; PMID: 21571567
   PubMed Web of Science ®Google Scholar
• Binello E, Germano IM. Targeting glioma stem cells: a novel framework for brain tumors. Cancer Sci 2011; 102:1958 - 66; http://dx.doi.org/10.1111/j.1349-7006.2011.02064.x; PMID: 21848914
   PubMed Web of Science ®Google Scholar
• Khain E, Katakowski M, Hopkins S, Szalad A, Zheng X, Jiang F, et al. Collective behavior of brain tumor cells: the role of hypoxia. Phys Rev E Stat Nonlin Soft Matter Phys 2011; 83:031920; http://dx.doi.org/10.1103/PhysRevE.83.031920; PMID: 21517536
   PubMedGoogle Scholar
• Siesser PF, Maness PF. L1 cell adhesion molecules as regulators of tumor cell invasiveness. Cell Adh Migr 2009; 3:275 - 7; http://dx.doi.org/10.4161/cam.3.3.8689; PMID: 19483471
   PubMed Web of Science ®Google Scholar
• Zhang N, Wei P, Gong A, Chiu WT, Lee HT, Colman H, et al. FoxM1 promotes β-catenin nuclear localization and controls Wnt target-gene expression and glioma tumorigenesis. Cancer Cell 2011; 20:427 - 42; http://dx.doi.org/10.1016/j.ccr.2011.08.016; PMID: 22014570
   PubMed Web of Science ®Google Scholar
• Friedl P, Alexander S. Cancer invasion and the microenvironment: plasticity and reciprocity. Cell 2011; 147:992 - 1009; http://dx.doi.org/10.1016/j.cell.2011.11.016; PMID: 22118458
   PubMed Web of Science ®Google Scholar
• Li HG, Ren YM, Guo SC, Cheng L, Wang DP, Yang J, et al. The protein level of hypoxia-inducible factor-1alpha is increased in the plateau pika (Ochotona curzoniae) inhabiting high altitudes. J Exp Zool A Ecol Genet Physiol 2009; 311:134 - 41; http://dx.doi.org/10.1002/jez.510; PMID: 19048601
   PubMed Web of Science ®Google Scholar
• Yi X, Liang Y, Huerta-Sanchez E, Jin X, Cuo ZX, Pool JE, et al. Sequencing of 50 human exomes reveals adaptation to high altitude. Science 2010; 329:75 - 8; http://dx.doi.org/10.1126/science.1190371; PMID: 20595611
   PubMed Web of Science ®Google Scholar
• Peng Y, Yang Z, Zhang H, Cui C, Qi X, Luo X, et al. Genetic variations in Tibetan populations and high-altitude adaptation at the Himalayas. Mol Biol Evol 2011; 28:1075 - 81; http://dx.doi.org/10.1093/molbev/msq290; PMID: 21030426
   PubMed Web of Science ®Google Scholar
• Storz JF, Scott GR, Cheviron ZA. Phenotypic plasticity and genetic adaptation to high-altitude hypoxia in vertebrates. J Exp Biol 2010; 213:4125 - 36; http://dx.doi.org/10.1242/jeb.048181; PMID: 21112992
   PubMed Web of Science ®Google Scholar
• Bigham A, Bauchet M, Pinto D, Mao X, Akey JM, Mei R, et al. Identifying signatures of natural selection in Tibetan and Andean populations using dense genome scan data. PLoS Genet 2010; 6:e1001116; http://dx.doi.org/10.1371/journal.pgen.1001116; PMID: 20838600
   PubMed Web of Science ®Google Scholar
• Simonson TS, Yang Y, Huff CD, Yun H, Qin G, Witherspoon DJ, et al. Genetic evidence for high-altitude adaptation in Tibet. Science 2010; 329:72 - 5; http://dx.doi.org/10.1126/science.1189406; PMID: 20466884
   PubMed Web of Science ®Google Scholar
• Zhou D, Xue J, Chen J, Morcillo P, Lambert JD, White KP, et al. Experimental selection for Drosophila survival in extremely low O(2) environment. PLoS One 2007; 2:e490; http://dx.doi.org/10.1371/journal.pone.0000490; PMID: 17534440
   PubMedGoogle Scholar
• Zhou D, Visk DW, Haddad GG. Drosophila, a golden bug, for the dissection of the genetic basis of tolerance and susceptibility to hypoxia. Pediatr Res 2009; 66:239 - 47; http://dx.doi.org/10.1203/PDR.0b013e3181b27275; PMID: 19542900
   PubMed Web of Science ®Google Scholar
• Shams I, Avivi A, Nevo E. Hypoxic stress tolerance of the blind subterranean mole rat: expression of erythropoietin and hypoxia-inducible factor 1 alpha. Proc Natl Acad Sci U S A 2004; 101:9698 - 703; http://dx.doi.org/10.1073/pnas.0403540101; PMID: 15210955
   PubMed Web of Science ®Google Scholar
• Shams I, Nevo E, Avivi A. Ontogenetic expression of erythropoietin and hypoxia-inducible factor-1 alpha genes in subterranean blind mole rats. FASEB J 2005; 19:307 - 9; PMID: 15574488
   PubMedGoogle Scholar
• Semenza GL. Hypoxia-inducible factor 1: regulator of mitochondrial metabolism and mediator of ischemic preconditioning. Biochim Biophys Acta 2011; 1813:1263 - 8; http://dx.doi.org/10.1016/j.bbamcr.2010.08.006; PMID: 20732359
   PubMed Web of Science ®Google Scholar
• Raymond J, Segrè D. The effect of oxygen on biochemical networks and the evolution of complex life. Science 2006; 311:1764 - 7; http://dx.doi.org/10.1126/science.1118439; PMID: 16556842
   PubMed Web of Science ®Google Scholar
• Broda E. The Evolution of the Bioenergetic Processes. Great Britain: Pergamon Press, 1978.
   Google Scholar
• Cavalier-Smith T. Cell evolution and Earth history: stasis and revolution. Philos Trans R Soc Lond B Biol Sci 2006; 361:969 - 1006; http://dx.doi.org/10.1098/rstb.2006.1842; PMID: 16754610
   PubMed Web of Science ®Google Scholar
• Holland HD. The oxygenation of the atmosphere and oceans. Philos Trans R Soc Lond B Biol Sci 2006; 361:903 - 15; http://dx.doi.org/10.1098/rstb.2006.1838; PMID: 16754606
   PubMed Web of Science ®Google Scholar
• Johnston DT, Wolfe-Simon F, Pearson A, Knoll AH. Anoxygenic photosynthesis modulated Proterozoic oxygen and sustained Earth’s middle age. Proc Natl Acad Sci U S A 2009; 106:16925 - 9; http://dx.doi.org/10.1073/pnas.0909248106; PMID: 19805080
   PubMed Web of Science ®Google Scholar
• Dahl TW, Hammarlund EU, Anbar AD, Bond DP, Gill BC, Gordon GW, et al. Devonian rise in atmospheric oxygen correlated to the radiations of terrestrial plants and large predatory fish. Proc Natl Acad Sci U S A 2010; 107:17911 - 5; http://dx.doi.org/10.1073/pnas.1011287107; PMID: 20884852
   PubMed Web of Science ®Google Scholar
• Dahl TW, Hammarlund EU. Do large predatory fish track ocean oxygenation?. Commun Integr Biol 2011; 4:92 - 4; http://dx.doi.org/10.4161/cib.4.1.14119; PMID: 21509191
   PubMedGoogle Scholar
• Williams M, Vannier J, Corbari L, Massabuau JC. Oxygen as a driver of early arthropod micro-benthos evolution. PLoS One 2011; 6:e28183; http://dx.doi.org/10.1371/journal.pone.0028183; PMID: 22164241
   PubMedGoogle Scholar
• Saltzman MR, Young SA, Kump LR, Gill BC, Lyons TW, Runnegar B. Pulse of atmospheric oxygen during the late Cambrian. Proc Natl Acad Sci U S A 2011; 108:3876 - 81; http://dx.doi.org/10.1073/pnas.1011836108; PMID: 21368152
   PubMed Web of Science ®Google Scholar
• Deutsch C, Brix H, Ito T, Frenzel H, Thompson L. Climate-forced variability of ocean hypoxia. Science 2011; 333:336 - 9; http://dx.doi.org/10.1126/science.1202422; PMID: 21659566
   PubMed Web of Science ®Google Scholar
• Hoffmann FG, Opazo JC, Storz JF. Differential loss and retention of cytoglobin, myoglobin, and globin-E during the radiation of vertebrates. Genome Biol Evol 2011; 3:588 - 600; http://dx.doi.org/10.1093/gbe/evr055; PMID: 21697098
   PubMed Web of Science ®Google Scholar
• Nothnagel HJ, Winer BY, Vuletich DA, Pond MP, Lecomte JT. Structural properties of 2/2 hemoglobins: the group III protein from Helicobacter hepaticus. IUBMB Life 2011; 63:197 - 205; http://dx.doi.org/10.1002/iub.430; PMID: 21445851
   PubMed Web of Science ®Google Scholar
• Ascenzi P, Bolognesi M, Milani M, Guertin M, Visca P. Mycobacterial truncated hemoglobins: from genes to functions. Gene 2007; 398:42 - 51; http://dx.doi.org/10.1016/j.gene.2007.02.043; PMID: 17532149
   PubMed Web of Science ®Google Scholar
• Freitas TA, Saito JA, Hou S, Alam M. Globin-coupled sensors, protoglobins, and the last universal common ancestor. J Inorg Biochem 2005; 99:23 - 33; http://dx.doi.org/10.1016/j.jinorgbio.2004.10.024; PMID: 15598488
   PubMed Web of Science ®Google Scholar
• Vuletich DA, Lecomte JT. A phylogenetic and structural analysis of truncated hemoglobins. J Mol Evol 2006; 62:196 - 210; http://dx.doi.org/10.1007/s00239-005-0077-4; PMID: 16474979
   PubMed Web of Science ®Google Scholar
• Summons RE, Bradley AS, Jahnke LL, Waldbauer JR. Steroids, triterpenoids and molecular oxygen. Philos Trans R Soc Lond B Biol Sci 2006; 361:951 - 68; http://dx.doi.org/10.1098/rstb.2006.1837; PMID: 16754609
   PubMed Web of Science ®Google Scholar
• Prochnik SE, Umen J, Nedelcu AM, Hallmann A, Miller SM, Nishii I, et al. Genomic analysis of organismal complexity in the multicellular green alga Volvox carteri. Science 2010; 329:223 - 6; http://dx.doi.org/10.1126/science.1188800; PMID: 20616280
   PubMed Web of Science ®Google Scholar
• Herron MD, Hackett JD, Aylward FO, Michod RE. Triassic origin and early radiation of multicellular volvocine algae. Proc Natl Acad Sci U S A 2009; 106:3254 - 8; http://dx.doi.org/10.1073/pnas.0811205106; PMID: 19223580
   PubMed Web of Science ®Google Scholar
• Forterre P, Philippe H. The last universal common ancestor (LUCA), simple or complex?. Biol Bull 1999; 196:373 - 5, discussion 375-7; http://dx.doi.org/10.2307/1542973; PMID: 11536914
   PubMed Web of Science ®Google Scholar
• Doolittle WF. Phylogenetic classification and the universal tree. Science 1999; 284:2124 - 9; http://dx.doi.org/10.1126/science.284.5423.2124; PMID: 10381871
   PubMed Web of Science ®Google Scholar
• Cavalier-Smith T. The neomuran origin of archaebacteria, the negibacterial root of the universal tree and bacterial megaclassification. Int J Syst Evol Microbiol 2002; 52:7 - 76; PMID: 11837318
   PubMed Web of Science ®Google Scholar
• Harris JK, Kelley ST, Spiegelman GB, Pace NR. The genetic core of the universal ancestor. Genome Res 2003; 13:407 - 12; http://dx.doi.org/10.1101/gr.652803; PMID: 12618371
   PubMed Web of Science ®Google Scholar
• Baymann F, Lebrun E, Brugna M, Schoepp-Cothenet B, Giudici-Orticoni MT, Nitschke W. The redox protein construction kit: pre-last universal common ancestor evolution of energy-conserving enzymes. Philos Trans R Soc Lond B Biol Sci 2003; 358:267 - 74; http://dx.doi.org/10.1098/rstb.2002.1184; PMID: 12594934
   PubMed Web of Science ®Google Scholar
• Margulis L. Symbiosis and evolution. Sci Am 1971; 225:48 - 57; http://dx.doi.org/10.1038/scientificamerican0871-48; PMID: 5089455
   PubMedGoogle Scholar
• Margulis L. Symbiotic theory of the origin of eukaryotic organelles; criteria for proof. Symp Soc Exp Biol 1975; 29:21 - 38; PMID: 822529
   PubMedGoogle Scholar
• Sagan D, Margulis L. Bacterial bedfellows: a microscopic menage a trois may be responsible for a major step in evolution. Nat Hist 1987; 96:26 - 33; PMID: 11542100
   PubMed Web of Science ®Google Scholar
• Guerrero R, Pedros-Alio C, Esteve I, Mas J, Chase D, Margulis L. Predatory prokaryotes: predation and primary consumption evolved in bacteria. Proc Natl Acad Sci U S A 1986; 83:2138 - 42; http://dx.doi.org/10.1073/pnas.83.7.2138; PMID: 11542073
   PubMed Web of Science ®Google Scholar
• Bauer CE, Elsen S, Bird TH. Mechanisms for redox control of gene expression. Annu Rev Microbiol 1999; 53:495 - 523; http://dx.doi.org/10.1146/annurev.micro.53.1.495; PMID: 10547699
   PubMed Web of Science ®Google Scholar
• Poyton RO. Models for oxygen sensing in yeast: implications for oxygen-regulated gene expression in higher eucaryotes. Respir Physiol 1999; 115:119 - 33; http://dx.doi.org/10.1016/S0034-5687(99)00028-6; PMID: 10385027
   PubMedGoogle Scholar
• Liu H, Colavitti R, Rovira II, Finkel T. Redox-dependent transcriptional regulation. Circ Res 2005; 97:967 - 74; http://dx.doi.org/10.1161/01.RES.0000188210.72062.10; PMID: 16284189
   PubMed Web of Science ®Google Scholar
• Shih SC, Claffey KP. Hypoxia-mediated regulation of gene expression in mammalian cells. Int J Exp Pathol 1998; 79:347 - 57; http://dx.doi.org/10.1046/j.1365-2613.1998.00088.x; PMID: 10319016
   PubMed Web of Science ®Google Scholar
• Huber O, Sumper M. Algal-CAMs: isoforms of a cell adhesion molecule in embryos of the alga Volvox with homology to Drosophila fasciclin I. EMBO J 1994; 13:4212 - 22; PMID: 7925267
   PubMed Web of Science ®Google Scholar
• Wenzl S, Sumper M. Sulfation of a cell surface glycoprotein correlates with the developmental program during embryogenesis of Volvox carteri. Proc Natl Acad Sci U S A 1981; 78:3716 - 20; http://dx.doi.org/10.1073/pnas.78.6.3716; PMID: 6943578
   PubMed Web of Science ®Google Scholar
• Hallmann A, Kirk DL. The developmentally regulated ECM glycoprotein ISG plays an essential role in organizing the ECM and orienting the cells of Volvox. J Cell Sci 2000; 113:4605 - 17; PMID: 11082052
   PubMed Web of Science ®Google Scholar
• Green KJ, Viamontes GI, Kirk DL. Mechanism of formation, ultrastructure, and function of the cytoplasmic bridge system during morphogenesis in Volvox. J Cell Biol 1981; 91:756 - 69; http://dx.doi.org/10.1083/jcb.91.3.756; PMID: 7328120
   PubMed Web of Science ®Google Scholar
• Sumper M, Hallmann A. Biochemistry of the extracellular matrix of Volvox. Int Rev Cytol 1998; 180:51 - 85; http://dx.doi.org/10.1016/S0074-7696(08)61770-2; PMID: 9496634
   PubMed Web of Science ®Google Scholar
• Ender F, Godl K, Wenzl S, Sumper M. Evidence for autocatalytic cross-linking of hydroxyproline-rich glycoproteins during extracellular matrix assembly in Volvox. Plant Cell 2002; 14:1147 - 60; http://dx.doi.org/10.1105/tpc.000711; PMID: 12034903
   PubMed Web of Science ®Google Scholar
• Sumper M, Nink J, Wenzl S. Self-assembly and cross-linking of Volvox extracellular matrix glycoproteins are specifically inhibited by Ellman’s reagent. Eur J Biochem 2000; 267:2334 - 9; http://dx.doi.org/10.1046/j.1432-1327.2000.01241.x; PMID: 10759858
   PubMedGoogle Scholar
• Siu CH, Harris TJ, Wang J, Wong E. Regulation of cell-cell adhesion during Dictyostelium development. Semin Cell Dev Biol 2004; 15:633 - 41; http://dx.doi.org/10.1016/j.semcdb.2004.09.004; PMID: 15561583
   PubMed Web of Science ®Google Scholar
• Bowers-Morrow VM, Ali SO, Williams KL. Comparison of molecular mechanisms mediating cell contact phenomena in model developmental systems: an exploration of universality. Biol Rev Camb Philos Soc 2004; 79:611 - 42; http://dx.doi.org/10.1017/S1464793103006389; PMID: 15366765
   PubMed Web of Science ®Google Scholar
• Siu CH, Sriskanthadevan S, Wang J, Hou L, Chen G, Xu X, et al. Regulation of spatiotemporal expression of cell-cell adhesion molecules during development of Dictyostelium discoideum. Dev Growth Differ 2011; 53:518 - 27; http://dx.doi.org/10.1111/j.1440-169X.2011.01267.x; PMID: 21585356
   PubMed Web of Science ®Google Scholar
• Sriskanthadevan S, Zhu Y, Manoharan K, Yang C, Siu CH. The cell adhesion molecule DdCAD-1 regulates morphogenesis through differential spatiotemporal expression in Dictyostelium discoideum. Development 2011; 138:2487 - 97; http://dx.doi.org/10.1242/dev.060129; PMID: 21561987
   PubMed Web of Science ®Google Scholar
• Kuspa A, Loomis WF. The Genome of Dictyostelium discoideum. Methods Mol Biol 2006; 346:15 - 30; http://dx.doi.org/10.1385/1-59745-144-4:15; PMID: 16957282
   PubMedGoogle Scholar
• Dickinson DJ, Nelson WJ, Weis WI. A polarized epithelium organized by beta- and alpha-catenin predates cadherin and metazoan origins. Science 2011; 331:1336 - 9; http://dx.doi.org/10.1126/science.1199633; PMID: 21393547
   PubMed Web of Science ®Google Scholar
• Fairclough SR, Dayel MJ, King N. Multicellular development in a choanoflagellate. Curr Biol 2010; 20:R875 - 6; http://dx.doi.org/10.1016/j.cub.2010.09.014; PMID: 20971426
   PubMedGoogle Scholar
• Ratcliff WC, Denison RF, Borrello M, Travisano M. Experimental evolution of multicellularity. Proc Natl Acad Sci USA 2012; 1009:1595 - 600; http://dx.doi.org/10.1073/pnas.1115323109; PMID: 22307617
   PubMed Web of Science ®Google Scholar
• Bekker A, Holland HD. Oxygen overshoot and recovery during the early Paleoproterozoic. Earth Planet Sci Lett 2012; 317-318:295 - 304; http://dx.doi.org/10.1016/j.epsl.2011.12.012
   Web of Science ®Google Scholar
• Roberts AM, Ohh M. Beyond the hypoxia-inducible factor-centric tumour suppressor model of von Hippel-Lindau. Curr Opin Oncol 2008; 20:83 - 9; http://dx.doi.org/10.1097/CCO.0b013e3282f310de; PMID: 18043261
   PubMed Web of Science ®Google Scholar
• Loenarz C, Coleman ML, Boleininger A, Schierwater B, Holland PW, Ratcliffe PJ, et al. The hypoxia-inducible transcription factor pathway regulates oxygen sensing in the simplest animal, Trichoplax adhaerens. EMBO Rep 2011; 12:63 - 70; http://dx.doi.org/10.1038/embor.2010.170; PMID: 21109780
   PubMed Web of Science ®Google Scholar
• Rytkönen KT, Storz JF. Evolutionary origins of oxygen sensing in animals. EMBO Rep 2011; 12:3 - 4; http://dx.doi.org/10.1038/embor.2010.192; PMID: 21109778
   PubMed Web of Science ®Google Scholar
• Zhang K, Zhu L, Fan M. Oxygen, a Key Factor Regulating Cell Behavior during Neurogenesis and Cerebral Diseases. Front Mol Neurosci 2011; 4:5; http://dx.doi.org/10.3389/fnmol.2011.00005; PMID: 21503147
   PubMed Web of Science ®Google Scholar
• Allen M, Louise Jones J. Jekyll and Hyde: the role of the microenvironment on the progression of cancer. J Pathol 2011; 223:162 - 76; http://dx.doi.org/10.1002/path.2803; PMID: 21125673
   PubMed Web of Science ®Google Scholar
• Welford SM, Giaccia AJ. Hypoxia and senescence: the impact of oxygenation on tumor suppression. Mol Cancer Res 2011; 9:538 - 44; http://dx.doi.org/10.1158/1541-7786.MCR-11-0065; PMID: 21385881
   PubMed Web of Science ®Google Scholar
• Semenza GL. Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics. Oncogene 2010; 29:625 - 34; http://dx.doi.org/10.1038/onc.2009.441; PMID: 19946328
   PubMed Web of Science ®Google Scholar
• Lu X, Kang Y. Hypoxia and hypoxia-inducible factors: master regulators of metastasis. Clin Cancer Res 2010; 16:5928 - 35; http://dx.doi.org/10.1158/1078-0432.CCR-10-1360; PMID: 20962028
   PubMed Web of Science ®Google Scholar
• Cassavaugh J, Lounsbury KM. Hypoxia-mediated biological control. J Cell Biochem 2011; 112:735 - 44; http://dx.doi.org/10.1002/jcb.22956; PMID: 21328446
   PubMed Web of Science ®Google Scholar
• El Albani A, Bengtson S, Canfield DE, Bekker A, Macchiarelli R, Mazurier A, et al. Large colonial organisms with coordinated growth in oxygenated environments 2.1 Gyr ago. Nature 2010; 466:100 - 4; http://dx.doi.org/10.1038/nature09166; PMID: 20596019
   PubMed Web of Science ®Google Scholar
• Semenza GL. Hypoxia inducible factors in physiology and medicine. Cell 2012; 148:399 - 408; http://dx.doi.org/10.1016/j.cell.2012.01.021; PMID: 22304911
   PubMed Web of Science ®Google Scholar