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Research Paper

Mesenchymal stem cells in mammary adipose tissue stimulate progression of breast cancer resembling the basal-type

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Pages 782-792 | Received 13 Feb 2012, Accepted 29 Apr 2012, Published online: 06 Jun 2012

References

  • Radisky ES, Radisky DC. Stromal induction of breast cancer: inflammation and invasion. Rev Endocr Metab Disord 2007; 8:279 - 87; http://dx.doi.org/10.1007/s11154-007-9037-1; PMID: 17447144
  • Egeblad M, Littlepage LE, Werb Z. The fibroblastic coconspirator in cancer progression. Cold Spring Harb Symp Quant Biol 2005; 70:383 - 8; http://dx.doi.org/10.1101/sqb.2005.70.007; PMID: 16869775
  • Zhao M, Dumur CI, Holt SE, Beckman MJ, Elmore LW. Multipotent adipose stromal cells and breast cancer development: Think globally, act locally. Mol Carcinog 2010; 49:923 - 7; http://dx.doi.org/10.1002/mc.20675; PMID: 20842668
  • Cleary MP, Grossmann ME. Minireview: Obesity and breast cancer: the estrogen connection. Endocrinology 2009; 150:2537 - 42; http://dx.doi.org/10.1210/en.2009-0070; PMID: 19372199
  • Roberts DL, Dive C, Renehan AG. Biological mechanisms linking obesity and cancer risk: new perspectives. Annu Rev Med 2010; 61:301 - 16; http://dx.doi.org/10.1146/annurev.med.080708.082713; PMID: 19824817
  • Boyd NF, Martin LJ, Chavez S, Gunasekara A, Salleh A, Melnichouk O, et al. Breast-tissue composition and other risk factors for breast cancer in young women: a cross-sectional study. Lancet Oncol 2009; 10:569 - 80; http://dx.doi.org/10.1016/S1470-2045(09)70078-6; PMID: 19409844
  • Millikan RC, Newman B, Tse CK, Moorman PG, Conway K, Dressler LG, et al. Epidemiology of basal-like breast cancer. Breast Cancer Res Treat 2008; 109:123 - 39; http://dx.doi.org/10.1007/s10549-007-9632-6; PMID: 17578664
  • Rakha EA, Ellis IO. Triple-negative/basal-like breast cancer: review. [review] Pathology 2009; 41:40 - 7; http://dx.doi.org/10.1080/00313020802563510; PMID: 19089739
  • Manabe Y, Toda S, Miyazaki K, Sugihara H. Mature adipocytes, but not preadipocytes, promote the growth of breast carcinoma cells in collagen gel matrix culture through cancer-stromal cell interactions. J Pathol 2003; 201:221 - 8; http://dx.doi.org/10.1002/path.1430; PMID: 14517839
  • Jotzu C, Al E, Welte G, Li J, Hennessy BT, Devarajan E, et al. Adipose tissue-derived stem cells differentiate into carcinoma-associated fibroblasts-like cells under the influence of tumor-derived factors. Anal. Cell Path. (Amst) 2010; 33:61 - 79
  • Bulun SE, Sharda G, Rink J, Sharma S, Simpson ER. Distribution of aromatase P450 transcripts and adipose fibroblasts in the human breast. J Clin Endocrinol Metab 1996; 81:1273 - 7; http://dx.doi.org/10.1210/jc.81.3.1273; PMID: 8772611
  • Ginsburg OM, Martin LJ, Boyd NF. Mammographic density, lobular involution and risk of breast cancer. Br J Cancer 2008; 99:1369 - 74; http://dx.doi.org/10.1038/sj.bjc.6604635; PMID: 18781174
  • Dumitrescu RG, Cotarla I. Understanding breast cancer risk-where do we stand in 2005?. J. Cell. Mol. Bio. 2005; 9:208 - 21
  • Rahimi N, Tremblay E, McAdam L, Roberts A, Elliott B. Autocrine secretion of TGF-beta 1 and TGF-beta 2 by pre-adipocytes and adipocytes: a potent negative regulator of adipocyte differentiation and proliferation of mammary carcinoma cells. In Vitro Cell Dev Biol Anim 1998; 34:412 - 20; http://dx.doi.org/10.1007/s11626-998-0023-z; PMID: 9639104
  • Zuk PA, Zhu M, Mizuno H, Huang J, Futrell JW, Katz AJ, et al. Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Eng 2001; 7:211 - 28; http://dx.doi.org/10.1089/107632701300062859; PMID: 11304456
  • Zuk PA, Zhu M, Ashjian P, De Ugarte DA, Huang JI, Mizuno H, et al. Human adipose tissue is a source of multipotent stem cells. Mol Biol Cell 2002; 13:4279 - 95; http://dx.doi.org/10.1091/mbc.E02-02-0105; PMID: 12475952
  • Gimble JM, Nuttall ME. Adipose-derived stromal/stem cells (ASC) in regenerative medicine: pharmaceutical applications. Curr Pharm Des 2011; 17:332 - 9; http://dx.doi.org/10.2174/138161211795164220; PMID: 21375497
  • Caimi PF, Reese J, Lee Z, Lazarus HM. Emerging therapeutic approaches for multipotent mesenchymal stromal cells. Curr Opin Hematol 2010; 17:505 - 13; http://dx.doi.org/10.1097/MOH.0b013e32833e5b18; PMID: 20729733
  • Schäffler A, Büchler C. Concise review: adipose tissue-derived stromal cells--basic and clinical implications for novel cell-based therapies. Stem Cells 2007; 25:818 - 27; http://dx.doi.org/10.1634/stemcells.2006-0589; PMID: 17420225
  • Karnoub AE, Dash AB, Vo AP, Sullivan A, Brooks MW, Bell GW, et al. Mesenchymal stem cells within tumour stroma promote breast cancer metastasis. Nature 2007; 449:557 - 63; http://dx.doi.org/10.1038/nature06188; PMID: 17914389
  • Ishii G, Sangai T, Oda T, Aoyagi Y, Hasebe T, Kanomata N, et al. Bone-marrow-derived myofibroblasts contribute to the cancer-induced stromal reaction. Biochem Biophys Res Commun 2003; 309:232 - 40; http://dx.doi.org/10.1016/S0006-291X(03)01544-4; PMID: 12943687
  • Goldstein RH, Reagan MR, Anderson K, Kaplan DL, Rosenblatt M. Human bone marrow-derived MSCs can home to orthotopic breast cancer tumors and promote bone metastasis. Cancer Res 2010; 70:10044 - 50; http://dx.doi.org/10.1158/0008-5472.CAN-10-1254; PMID: 21159629
  • Muehlberg FL, Song YH, Krohn A, Pinilla SP, Droll LH, Leng X, et al. Tissue-resident stem cells promote breast cancer growth and metastasis. Carcinogenesis 2009; 30:589 - 97; http://dx.doi.org/10.1093/carcin/bgp036; PMID: 19181699
  • Sun B, Roh KH, Park JR, Lee SR, Park SB, Jung JW, et al. Therapeutic potential of mesenchymal stromal cells in a mouse breast cancer metastasis model. Cytotherapy 2009; 11:289 - 98, 1, 298; http://dx.doi.org/10.1080/14653240902807026; PMID: 19308770
  • Welte G, Alt E, Devarajan E, Krishnappa S, Jotzu C, Song YH. Interleukin-8 derived from the local tissue-resident stromals cells promotes cell invasion. Mol. Carcinogenesis 2011;
  • Razmkhah M, Jaberipour M, Erfani N, Habibagahi M, Talei AR, Ghaderi A. Adipose derived stem cells (ASCs) isolated from breast cancer tissue express IL-4, IL-10 and TGF-β1 and upregulate expression of regulatory molecules on T cells: do they protect breast cancer cells from the immune response?. Cell Immunol 2011; 266:116 - 22; http://dx.doi.org/10.1016/j.cellimm.2010.09.005; PMID: 20970781
  • Mishra PJ, Mishra PJ, Humeniuk R, Medina DJ, Alexe G, Mesirov JP, et al. Carcinoma-associated fibroblast-like differentiation of human mesenchymal stem cells. Cancer Res 2008; 68:4331 - 9; http://dx.doi.org/10.1158/0008-5472.CAN-08-0943; PMID: 18519693
  • Haviv I, Polyak K, Qiu W, Hu M, Campbell I. Origin of carcinoma associated fibroblasts. Cell Cycle 2009; 8:589 - 95; http://dx.doi.org/10.4161/cc.8.4.7669; PMID: 19182519
  • Zhang Y, Daquinag A, Traktuev DO, Amaya-Manzanares F, Simmons PJ, March KL, et al. White adipose tissue cells are recruited by experimental tumors and promote cancer progression in mouse models. Cancer Res 2009; 69:5259 - 66; http://dx.doi.org/10.1158/0008-5472.CAN-08-3444; PMID: 19491274
  • Rizki A, Weaver VM, Lee SY, Rozenberg GI, Chin K, Myers CA, et al. A human breast cell model of preinvasive to invasive transition. Cancer Res 2008; 68:1378 - 87; http://dx.doi.org/10.1158/0008-5472.CAN-07-2225; PMID: 18316601
  • Rundhaug JE. Matrix metalloproteinases and angiogenesis. J Cell Mol Med 2005; 9:267 - 85; http://dx.doi.org/10.1111/j.1582-4934.2005.tb00355.x; PMID: 15963249
  • Blasi A, Martino C, Balducci L, Saldarelli M, Soleti A, Navone SE, et al. Dermal fibroblasts display similar phenotypic and differentiation capacaity to fat-derived mesenchymal stem cells, but differ in anti-inflammatory and angiogenic potential. Vacular Cell 2011; 3:5; http://dx.doi.org/10.1186/2045-824X-3-5
  • Kinnaird T, Stabile E, Burnett MS, Lee CW, Barr S, Fuchs S, et al. Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanisms. Circ Res 2004; 94:678 - 85; http://dx.doi.org/10.1161/01.RES.0000118601.37875.AC; PMID: 14739163
  • Sumi M, Sata M, Toya N, Yanaga K, Ohki T, Nagai R. Transplantation of adipose stromal cells, but not mature adipocytes, augments ischemia-induced angiogenesis. Life Sci 2007; 80:559 - 65; http://dx.doi.org/10.1016/j.lfs.2006.10.020; PMID: 17157325
  • Kang Y, Park C, Kim D, Seong CM, Kwon K, Choi C. Unsorted human adipose tissue-derived stem cells promote angiogenesis and myogenesis in murine ischemic hindlimb model. Microvasc Res 2010; 80:310 - 6; http://dx.doi.org/10.1016/j.mvr.2010.05.006; PMID: 20510252
  • Cao Y, Sun Z, Liao L, Meng Y, Han Q, Zhao RC. Human adipose tissue-derived stem cells differentiate into endothelial cells in vitro and improve postnatal neovascularization in vivo. Biochem Biophys Res Commun 2005; 332:370 - 9; http://dx.doi.org/10.1016/j.bbrc.2005.04.135; PMID: 15896706
  • Liao D, Johnson RS. Hypoxia: a key regulator of angiogenesis in cancer. Cancer Metastasis Rev 2007; 26:281 - 90; http://dx.doi.org/10.1007/s10555-007-9066-y; PMID: 17603752
  • de Ferranti S, Mozaffarian D. The perfect storm: obesity, adipocyte dysfunction and metabolic consequences. Clin Chem 2008; 54:945 - 55; http://dx.doi.org/10.1373/clinchem.2007.100156; PMID: 18436717
  • Francis MP, Sachs PC, Elmore LW, Holt SE. Isolating adipose-derived mesenchymal stem cells from lipoaspirate blood and saline fraction. Organogenesis 2010; 6:11 - 4; http://dx.doi.org/10.4161/org.6.1.10019; PMID: 20592860
  • Forsythe HL, Elmore LW, Jensen KO, Landon MR, Holt SE. Retroviral-mediated expression of telomerase in normal human cells provides a selective growth advantage. Int J Oncol 2002; 20:1137 - 43; PMID: 12011990
  • Dumur CI, Ladd AC, Wright HV, Penberthy LT, Wilkinson DS, Powers CN, et al. Genes involved in radiation therapy response in head and neck cancers. Laryngoscope 2009; 119:91 - 101; http://dx.doi.org/10.1002/lary.20005; PMID: 19117295
  • Diehl MC, Idowu MO, Kimmelshue KN, York TP, Jackson-Cook CK, Turner KC, et al. Elevated TRF2 in advanced breast cancers with short telomeres. Breast Cancer Res Treat 2011; 127:623 - 30; http://dx.doi.org/10.1007/s10549-010-0988-7; PMID: 20625812
  • Brown PD, Levy AT, Margulies IM, Liotta LA, Stetler-Stevenson WG. Independent expression and cellular processing of Mr 72,000 type IV collagenase and interstitial collagenase in human tumorigenic cell lines. Cancer Res 1990; 50:6184 - 91; PMID: 2169338
  • Ellerbroek SM, Wu YI, Overall CM, Stack MS. Functional interplay between type I collagen and cell surface matrix metalloproteinase activity. J Biol Chem 2001; 276:24833 - 42; http://dx.doi.org/10.1074/jbc.M005631200; PMID: 11331272
  • Debnath J, Muthuswamy SK, Brugge JS. Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods 2003; 30:256 - 68; http://dx.doi.org/10.1016/S1046-2023(03)00032-X; PMID: 12798140
  • Wosnitza M, Hemmrich K, Groger A, Gräber S, Pallua N. Plasticity of human adipose stem cells to perform adipogenic and endothelial differentiation. Differentiation 2007; 75:12 - 23; http://dx.doi.org/10.1111/j.1432-0436.2006.00110.x; PMID: 17244018
  • Lozito TP, Kuo CK, Taboas JM, Tuan RS. Human mesenchymal stem cells express vascular cell phenotypes upon interaction with endothelial cell matrix. J Cell Biochem 2009; 107:714 - 22; http://dx.doi.org/10.1002/jcb.22167; PMID: 19415687
  • Oswald J, Boxberger S, Jørgensen B, Feldmann S, Ehninger G, Bornhäuser M, et al. Mesenchymal stem cells can be differentiated into endothelial cells in vitro. Stem Cells 2004; 22:377 - 84; http://dx.doi.org/10.1634/stemcells.22-3-377; PMID: 15153614

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