Dissecting the complex regulation of Mad4 in glioblastoma multiforme cells

References

• Li Z, Van Calcar S, Qu C, Cavenee WK, Zhang MQ, Ren B. A global transcriptional regulatory role for c-Myc in Burkitt’s lymphoma cells. Proc Natl Acad Sci U S A 2003; 100:8164 - 9; http://dx.doi.org/10.1073/pnas.1332764100; PMID: 12808131
   PubMed Web of Science ®Google Scholar
• Perna D, Fagà G, Verrecchia A, Gorski MM, Barozzi I, Narang V, et al. Genome-wide mapping of Myc binding and gene regulation in serum-stimulated fibroblasts. Oncogene 2012; 31:1695 - 709; http://dx.doi.org/10.1038/onc.2011.359; PMID: 21860422
   PubMed Web of Science ®Google Scholar
• Lüscher B, Larsson LG. The basic region/helix-loop-helix/leucine zipper domain of Myc proto-oncoproteins: function and regulation. Oncogene 1999; 18:2955 - 66; http://dx.doi.org/10.1038/sj.onc.1202750; PMID: 10378692
   PubMed Web of Science ®Google Scholar
• Hurlin PJ, Huang J. The MAX-interacting transcription factor network. Semin Cancer Biol 2006; 16:265 - 74; http://dx.doi.org/10.1016/j.semcancer.2006.07.009; PMID: 16908182
   PubMed Web of Science ®Google Scholar
• Adhikary S, Eilers M. Transcriptional regulation and transformation by Myc proteins. Nat Rev Mol Cell Biol 2005; 6:635 - 45; http://dx.doi.org/10.1038/nrm1703; PMID: 16064138
   PubMed Web of Science ®Google Scholar
• Marcotte R, Qian JF, Chen J, Wang E. hMad4, c-Myc endogenous inhibitor, induces a replicative senescence-like state when overexpressed in human fibroblasts. J Cell Biochem 2003; 89:576 - 88; http://dx.doi.org/10.1002/jcb.10517; PMID: 12761891
   PubMed Web of Science ®Google Scholar
• David G, Grandinetti KB, Finnerty PM, Simpson N, Chu GC, Depinho RA. Specific requirement of the chromatin modifier mSin3B in cell cycle exit and cellular differentiation. Proc Natl Acad Sci U S A 2008; 105:4168 - 72; http://dx.doi.org/10.1073/pnas.0710285105; PMID: 18332431
   PubMed Web of Science ®Google Scholar
• Grandinetti KB, Jelinic P, DiMauro T, Pellegrino J, Fernández Rodríguez R, Finnerty PM, et al. Sin3B expression is required for cellular senescence and is up-regulated upon oncogenic stress. Cancer Res 2009; 69:6430 - 7; http://dx.doi.org/10.1158/0008-5472.CAN-09-0537; PMID: 19654306
   PubMed Web of Science ®Google Scholar
• Jelinic P, Pellegrino J, David G. A novel mammalian complex containing Sin3B mitigates histone acetylation and RNA polymerase II progression within transcribed loci. Mol Cell Biol 2011; 31:54 - 62; http://dx.doi.org/10.1128/MCB.00840-10; PMID: 21041482
   PubMed Web of Science ®Google Scholar
• Dannenberg JH, David G, Zhong S, van der Torre J, Wong WH, Depinho RA. mSin3A corepressor regulates diverse transcriptional networks governing normal and neoplastic growth and survival. Genes Dev 2005; 19:1581 - 95; http://dx.doi.org/10.1101/gad.1286905; PMID: 15998811
   PubMed Web of Science ®Google Scholar
• Xu L, Zhu J, Hu X, Zhu H, Kim HT, LaBaer J, et al. c-IAP1 cooperates with Myc by acting as a ubiquitin ligase for Mad1. Mol Cell 2007; 28:914 - 22; http://dx.doi.org/10.1016/j.molcel.2007.10.027; PMID: 18082613
   PubMed Web of Science ®Google Scholar
• Srinivasula SM, Ashwell JD. IAPs: what’s in a name?. Mol Cell 2008; 30:123 - 35; http://dx.doi.org/10.1016/j.molcel.2008.03.008; PMID: 18439892
   PubMed Web of Science ®Google Scholar
• Gyrd-Hansen M, Meier P. IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer. Nat Rev Cancer 2010; 10:561 - 74; http://dx.doi.org/10.1038/nrc2889; PMID: 20651737
   PubMed Web of Science ®Google Scholar
• Li X, Yang Y, Ashwell JD. TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2. Nature 2002; 416:345 - 7; http://dx.doi.org/10.1038/416345a; PMID: 11907583
   PubMed Web of Science ®Google Scholar
• Conze DB, Albert L, Ferrick DA, Goeddel DV, Yeh WC, Mak T, et al. Posttranscriptional downregulation of c-IAP2 by the ubiquitin protein ligase c-IAP1 in vivo. Mol Cell Biol 2005; 25:3348 - 56; http://dx.doi.org/10.1128/MCB.25.8.3348-3356.2005; PMID: 15798218
   PubMed Web of Science ®Google Scholar
• Zhao Y, Conze DB, Hanover JA, Ashwell JD. Tumor necrosis factor receptor 2 signaling induces selective c-IAP1-dependent ASK1 ubiquitination and terminates mitogen-activated protein kinase signaling. J Biol Chem 2007; 282:7777 - 82; http://dx.doi.org/10.1074/jbc.M609146200; PMID: 17220297
   PubMed Web of Science ®Google Scholar
• Csomos RA, Brady GF, Duckett CS. Enhanced cytoprotective effects of the inhibitor of apoptosis protein cellular IAP1 through stabilization with TRAF2. J Biol Chem 2009; 284:20531 - 9; http://dx.doi.org/10.1074/jbc.M109.029983; PMID: 19506082
   PubMed Web of Science ®Google Scholar
• Verhaak RG, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD, et al, Cancer Genome Atlas Research Network. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR and NF1. Cancer Cell 2010; 17:98 - 110; http://dx.doi.org/10.1016/j.ccr.2009.12.020; PMID: 20129251
   PubMed Web of Science ®Google Scholar
• Marcotte R, Chen JM, Huard S, Wang E. c-Myc creates an activation loop by transcriptionally repressing its own functional inhibitor, hMad4, in young fibroblasts, a loop lost in replicatively senescent fibroblasts. J Cell Biochem 2005; 96:1071 - 85; http://dx.doi.org/10.1002/jcb.20503; PMID: 16167342
   PubMed Web of Science ®Google Scholar
• Sears R, Leone G, DeGregori J, Nevins JR. Ras enhances Myc protein stability. Mol Cell 1999; 3:169 - 79; http://dx.doi.org/10.1016/S1097-2765(00)80308-1; PMID: 10078200
   PubMed Web of Science ®Google Scholar
• Kong Q, Zeng W, Wu J, Hu W, Li C, Mao B. RNF220, an E3 ubiquitin ligase that targets Sin3B for ubiquitination. Biochem Biophys Res Commun 2010; 393:708 - 13; http://dx.doi.org/10.1016/j.bbrc.2010.02.066; PMID: 20170641
   PubMed Web of Science ®Google Scholar
• Linares LK, Kiernan R, Triboulet R, Chable-Bessia C, Latreille D, Cuvier O, et al. Intrinsic ubiquitination activity of PCAF controls the stability of the oncoprotein Hdm2. Nat Cell Biol 2007; 9:331 - 8; http://dx.doi.org/10.1038/ncb1545; PMID: 17293853
   PubMed Web of Science ®Google Scholar
• Noerholm M, Balaj L, Limperg T, Salehi A, Zhu LD, Hochberg FH, et al. RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls. BMC Cancer 2012; 12:22; http://dx.doi.org/10.1186/1471-2407-12-22; PMID: 22251860
   PubMed Web of Science ®Google Scholar
• Wang Y, Engels IH, Knee DA, Nasoff M, Deveraux QL, Quon KC. Synthetic lethal targeting of MYC by activation of the DR5 death receptor pathway. Cancer Cell 2004; 5:501 - 12; http://dx.doi.org/10.1016/S1535-6108(04)00113-8; PMID: 15144957
   PubMed Web of Science ®Google Scholar
• Nieminen AI, Partanen JI, Hau A, Klefstrom J. c-Myc primed mitochondria determine cellular sensitivity to TRAIL-induced apoptosis. EMBO J 2007; 26:1055 - 67; http://dx.doi.org/10.1038/sj.emboj.7601551; PMID: 17268552
   PubMed Web of Science ®Google Scholar
• Larsson LG, Henriksson MA. The Yin and Yang functions of the Myc oncoprotein in cancer development and as targets for therapy. Exp Cell Res 2010; 316:1429 - 37; http://dx.doi.org/10.1016/j.yexcr.2010.03.025; PMID: 20382143
   PubMed Web of Science ®Google Scholar
• Mateyak MK, Obaya AJ, Adachi S, Sedivy JM. Phenotypes of c-Myc-deficient rat fibroblasts isolated by targeted homologous recombination. Cell Growth Differ 1997; 8:1039 - 48; PMID: 9342182
   PubMedGoogle Scholar
• Mei Y, Hahn AA, Hu S, Yang X. The USP19 deubiquitinase regulates the stability of c-IAP1 and c-IAP2. J Biol Chem 2011; 286:35380 - 7; http://dx.doi.org/10.1074/jbc.M111.282020; PMID: 21849505
   PubMed Web of Science ®Google Scholar