917
Views
38
CrossRef citations to date
0
Altmetric
Research Paper

Photodynamic therapy activated signaling from epidermal growth factor receptor and STAT3

Targeting survival pathways to increase PDT efficacy in ovarian and lung cancer

, , , &
Pages 1463-1470 | Received 07 Sep 2012, Accepted 17 Sep 2012, Published online: 17 Sep 2012

References

  • Cengel KA, Hahn SM. Photodynamic Therapy. Cancer 2008; 767 - 74; PMID: 18098271
  • Busch TM, Hahn SM, Wileyto EP, Koch CJ, Fraker DL, Zhang P, et al. Hypoxia and Photofrin uptake in the intraperitoneal carcinomatosis and sarcomatosis of photodynamic therapy patients. Clin Cancer Res 2004; 10:4630 - 8; http://dx.doi.org/10.1158/1078-0432.CCR-04-0359; PMID: 15269134
  • Hahn SM, Fraker DL, Mick R, Metz J, Busch TM, Smith D, et al. A phase II trial of intraperitoneal photodynamic therapy for patients with peritoneal carcinomatosis and sarcomatosis. Clin Cancer Res 2006; 12:2517 - 25; http://dx.doi.org/10.1158/1078-0432.CCR-05-1625; PMID: 16638861
  • Hahn SM, Putt ME, Metz J, Shin DB, Rickter E, Menon C, et al. Photofrin uptake in the tumor and normal tissues of patients receiving intraperitoneal photodynamic therapy. Clin Cancer Res 2006; 12:5464 - 70; http://dx.doi.org/10.1158/1078-0432.CCR-06-0953; PMID: 17000681
  • Friedberg J, Cengel K. Pleural Malignancies. Semin Radiat Oncol 2009; 20:208 - 14; PMID: 20685584
  • Cengel KA, Glatstein E, Hahn SM. Intraperitoneal photodynamic therapy. Cancer Treat Res 2007; 134:493 - 514; PMID: 17633077
  • Solban N, Rizvi I, Hasan T. Targeted photodynamic therapy. Lasers Surg Med 2006; 38:522 - 31; http://dx.doi.org/10.1002/lsm.20345; PMID: 16671102
  • Almeida RD, Manadas BJ, Carvalho AP, Duarte CB. Intracellular signaling mechanisms in photodynamic therapy. Biochim Biophys Acta 2004; 1704:59 - 86; PMID: 15363861
  • Cengel KA, Hahn SM, Glatstein E. C225 and PDT combination therapy for ovarian cancer: the play’s the thing. J Natl Cancer Inst 2005; 97:1488 - 9; http://dx.doi.org/10.1093/jnci/dji360; PMID: 16234556
  • del Carmen MG, Rizvi I, Chang Y, Moor AC, Oliva E, Sherwood M, et al. Synergism of epidermal growth factor receptor-targeted immunotherapy with photodynamic treatment of ovarian cancer in vivo. J Natl Cancer Inst 2005; 97:1516 - 24; http://dx.doi.org/10.1093/jnci/dji314; PMID: 16234565
  • Fontanini G, De Laurentiis M, Vignati S, Chinè S, Lucchi M, Silvestri V, et al. Evaluation of epidermal growth factor-related growth factors and receptors and of neoangiogenesis in completely resected stage I-IIIA non-small-cell lung cancer: amphiregulin and microvessel count are independent prognostic indicators of survival. Clin Cancer Res 1998; 4:241 - 9; PMID: 9516978
  • Ahmad N, Kalka K, Mukhtar H. In vitro and in vivo inhibition of epidermal growth factor receptor-tyrosine kinase pathway by photodynamic therapy. Oncogene 2001; 20:2314 - 7; http://dx.doi.org/10.1038/sj.onc.1204313; PMID: 11402326
  • Wong TW, Tracy E, Oseroff AR, Baumann H. Photodynamic therapy mediates immediate loss of cellular responsiveness to cytokines and growth factors. Cancer Res 2003; 63:3812 - 8; PMID: 12839978
  • Liu W, Oseroff AR, Baumann H. Photodynamic therapy causes cross-linking of signal transducer and activator of transcription proteins and attenuation of interleukin-6 cytokine responsiveness in epithelial cells. Cancer Res 2004; 64:6579 - 87; http://dx.doi.org/10.1158/0008-5472.CAN-04-1580; PMID: 15374971
  • Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, Brannigan BW, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004; 350:2129 - 39; http://dx.doi.org/10.1056/NEJMoa040938; PMID: 15118073
  • Helfrich BA, Raben D, Varella-Garcia M, Gustafson D, Chan DC, Bemis L, et al. Antitumor activity of the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor gefitinib (ZD1839, Iressa) in non-small cell lung cancer cell lines correlates with gene copy number and EGFR mutations but not EGFR protein levels. Clin Cancer Res 2006; 12:7117 - 25; http://dx.doi.org/10.1158/1078-0432.CCR-06-0760; PMID: 17145836
  • Thomson S, Buck E, Petti F, Griffin G, Brown E, Ramnarine N, et al. Epithelial to mesenchymal transition is a determinant of sensitivity of non-small-cell lung carcinoma cell lines and xenografts to epidermal growth factor receptor inhibition. Cancer Res 2005; 65:9455 - 62; http://dx.doi.org/10.1158/0008-5472.CAN-05-1058; PMID: 16230409
  • Sewell JM, Macleod KG, Ritchie A, Smyth JF, Langdon SP. Targeting the EGF receptor in ovarian cancer with the tyrosine kinase inhibitor ZD 1839 (“Iressa”). Br J Cancer 2002; 86:456 - 62; http://dx.doi.org/10.1038/sj.bjc.6600058; PMID: 11875715
  • Li C, Iida M, Dunn EF, Ghia AJ, Wheeler DL. Nuclear EGFR contributes to acquired resistance to cetuximab. Oncogene 2009; 28:3801 - 13; http://dx.doi.org/10.1038/onc.2009.234; PMID: 19684613
  • Wang SC, Hung MC. Nuclear translocation of the epidermal growth factor receptor family membrane tyrosine kinase receptors. Clin Cancer Res 2009; 15:6484 - 9; http://dx.doi.org/10.1158/1078-0432.CCR-08-2813; PMID: 19861462
  • Henderson BW, Daroqui C, Tracy E, Vaughan LA, Loewen GM, Cooper MT, et al. Cross-linking of signal transducer and activator of transcription 3--a molecular marker for the photodynamic reaction in cells and tumors. Clin Cancer Res 2007; 13:3156 - 63; http://dx.doi.org/10.1158/1078-0432.CCR-06-2950; PMID: 17545518
  • Liu W, Baer MR, Bowman MJ, Pera P, Zheng X, Morgan J, et al. The tyrosine kinase inhibitor imatinib mesylate enhances the efficacy of photodynamic therapy by inhibiting ABCG2. Clin Cancer Res 2007; 13:2463 - 70; http://dx.doi.org/10.1158/1078-0432.CCR-06-1599; PMID: 17438106
  • Cengel KA, Voong KR, Chandrasekaran S, Maggiorella L, Brunner TB, Stanbridge E, et al. Oncogenic K-Ras signals through epidermal growth factor receptor and wild-type H-Ras to promote radiation survival in pancreatic and colorectal carcinoma cells. Neoplasia 2007; 9:341 - 8; http://dx.doi.org/10.1593/neo.06823; PMID: 17460778
  • Godbout JP, Cengel KA, Cheng SL, Minshall C, Kelley KW, Freund GG. Insulin activates caspase-3 by a phosphatidylinositol 3′-kinase-dependent pathway. Cell Signal 1999; 11:15 - 23; http://dx.doi.org/10.1016/S0898-6568(98)00024-2; PMID: 10206340
  • Agostinis P, Donella-Deana A, Cuveele J, Vandenbogaerde A, Sarno S, Merlevede W, et al. A comparative analysis of the photosensitized inhibition of growth-factor regulated protein kinases by hypericin-derivatives. Biochem Biophys Res Commun 1996; 220:613 - 7; http://dx.doi.org/10.1006/bbrc.1996.0451; PMID: 8607812
  • Shi Z, Peng XX, Kim IW, Shukla S, Si QS, Robey RW, et al. Erlotinib (Tarceva, OSI-774) antagonizes ATP-binding cassette subfamily B member 1 and ATP-binding cassette subfamily G member 2-mediated drug resistance. Cancer Res 2007; 67:11012 - 20; http://dx.doi.org/10.1158/0008-5472.CAN-07-2686; PMID: 18006847
  • Brunner TB, Cengel KA, Hahn SM, Wu J, Fraker DL, McKenna WG, et al. Pancreatic cancer cell radiation survival and prenyltransferase inhibition: the role of K-Ras. Cancer Res 2005; 65:8433 - 41; http://dx.doi.org/10.1158/0008-5472.CAN-05-0158; PMID: 16166322
  • Cengel KA, Kason RE, Freund GG. Phosphatidylinositol 3′-kinase associates with an insulin receptor substrate-1 serine kinase distinct from its intrinsic serine kinase. Biochem J 1998; 335:397 - 404; PMID: 9761740
  • Cengel KA, Freund GG. JAK1-dependent phosphorylation of insulin receptor substrate-1 (IRS-1) is inhibited by IRS-1 serine phosphorylation. J Biol Chem 1999; 274:27969 - 74; http://dx.doi.org/10.1074/jbc.274.39.27969; PMID: 10488146
  • Horan AD, Giandomenico AR, Koch CJ. Effect of oxygen on radiation-induced DNA damage in isolated nuclei. Radiat Res 1999; 152:144 - 53; http://dx.doi.org/10.2307/3580087; PMID: 10409323
  • Dowling M, Voong KR, Kim M, Keutmann MK, Harris E, Kao GD. Mitotic spindle checkpoint inactivation by trichostatin a defines a mechanism for increasing cancer cell killing by microtubule-disrupting agents. Cancer Biol Ther 2005; 4:197 - 206; http://dx.doi.org/10.4161/cbt.4.2.1441; PMID: 15753652
  • Harris EE, Hwang WT, Lee EA, Cengel KA, Feldman MD, Demichele A, et al. The impact of HER-2 status on local recurrence in women with stage I-II breast cancer treated with breast-conserving therapy. Breast J 2006; 12:431 - 6; http://dx.doi.org/10.1111/j.1075-122X.2006.00297.x; PMID: 16958961
  • Cengel KA, Deutsch E, Stephens TC, Voong KR, Kao GD, Bernhard EJ. Radiosensitizing effects of the prenyltransferase inhibitor AZD3409 against RAS mutated cell lines. Cancer Biol Ther 2006; 5:1206 - 10; http://dx.doi.org/10.4161/cbt.5.9.3172; PMID: 16969121

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.