Parthenolide reduces the frequency of ABCB5-positive cells and clonogenic capacity of melanoma cells from anchorage independent melanospheres

References

• Schatton T, Frank MH. Cancer stem cells and human malignant melanoma. Pigment Cell Melanoma Res 2008; 21:39 - 55; http://dx.doi.org/10.1111/j.1755-148X.2007.00427.x; PMID: 18353142
   PubMed Web of Science ®Google Scholar
• Frank NY, Schatton T, Frank MH. The therapeutic promise of the cancer stem cell concept. J Clin Invest 2010; 120:41 - 50; http://dx.doi.org/10.1172/JCI41004; PMID: 20051635
   PubMed Web of Science ®Google Scholar
• Girouard SD, Murphy GF. Melanoma stem cells: not rare, but well done. Lab Invest 2011; 91:647 - 64; http://dx.doi.org/10.1038/labinvest.2011.50; PMID: 21445060
   PubMed Web of Science ®Google Scholar
• Eramo A, Haas TL, De Maria R. Lung cancer stem cells: tools and targets to fight lung cancer. Oncogene 2010; 29:4625 - 35; http://dx.doi.org/10.1038/onc.2010.207; PMID: 20531299
   PubMed Web of Science ®Google Scholar
• Takehara M, Hoshino T, Namba T, Yamakawa N, Mizushima T. Acetaminophen-induced differentiation of human breast cancer stem cells and inhibition of tumor xenograft growth in mice. Biochem Pharmacol 2011; 81:1124 - 35; http://dx.doi.org/10.1016/j.bcp.2011.02.012; PMID: 21371442
   PubMed Web of Science ®Google Scholar
• Schmidt P, Kopecky C, Hombach A, Zigrino P, Mauch C, Abken H. Eradication of melanomas by targeted elimination of a minor subset of tumor cells. Proc Natl Acad Sci U S A 2011; 108:2474 - 9; http://dx.doi.org/10.1073/pnas.1009069108; PMID: 21282657
   PubMed Web of Science ®Google Scholar
• Quintana E, Shackleton M, Foster HR, Fullen DR, Sabel MS, Johnson TM, et al. Phenotypic heterogeneity among tumorigenic melanoma cells from patients that is reversible and not hierarchically organized. Cancer Cell 2010; 18:510 - 23; http://dx.doi.org/10.1016/j.ccr.2010.10.012; PMID: 21075313
   PubMed Web of Science ®Google Scholar
• Hoek KS, Goding CR. Cancer stem cells versus phenotype-switching in melanoma. Pigment Cell Melanoma Res 2010; 23:746 - 59; http://dx.doi.org/10.1111/j.1755-148X.2010.00757.x; PMID: 20726948
   PubMed Web of Science ®Google Scholar
• Roesch A, Fukunaga-Kalabis M, Schmidt EC, Zabierowski SE, Brafford PA, Vultur A, et al. A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth. Cell 2010; 141:583 - 94; http://dx.doi.org/10.1016/j.cell.2010.04.020; PMID: 20478252
   PubMed Web of Science ®Google Scholar
• Abel EV, Aplin AE. Finding the root of the problem: the quest to identify melanoma stem cells. Front Biosci (Schol Ed) 2011; 3:937 - 45; http://dx.doi.org/10.2741/198; PMID: 21622243
   PubMedGoogle Scholar
• Fukunaga-Kalabis M, Roesch A, Herlyn M. From cancer stem cells to tumor maintenance in melanoma. J Invest Dermatol 2011; 131:1600 - 4; http://dx.doi.org/10.1038/jid.2011.159; PMID: 21654838
   PubMed Web of Science ®Google Scholar
• Ghislin S, Deshayes F, Lauriol J, Middendorp S, Martins I, Al-Daccak R, et al. Plasticity of melanoma cells induced by neural cell crest conditions and three-dimensional growth. Melanoma Res 2012; 22:184 - 94; http://dx.doi.org/10.1097/CMR.0b013e328351e7c4; PMID: 22454190
   PubMed Web of Science ®Google Scholar
• Sztiller-Sikorska M, Koprowska K, Jakubowska J, Zalesna I, Stasiak M, Duechler M, et al. Sphere formation and self-renewal capacity of melanoma cells is affected by the microenvironment. Melanoma Res 2012; 22:215 - 24; http://dx.doi.org/10.1097/CMR.0b013e3283531317; PMID: 22495670
   PubMed Web of Science ®Google Scholar
• Wen J, You KR, Lee SY, Song CH, Kim DG. Oxidative stress-mediated apoptosis. The anticancer effect of the sesquiterpene lactone parthenolide. J Biol Chem 2002; 277:38954 - 64; http://dx.doi.org/10.1074/jbc.M203842200; PMID: 12151389
   PubMed Web of Science ®Google Scholar
• Zunino SJ, Ducore JM, Storms DH. Parthenolide induces significant apoptosis and production of reactive oxygen species in high-risk pre-B leukemia cells. Cancer Lett 2007; 254:119 - 27; http://dx.doi.org/10.1016/j.canlet.2007.03.002; PMID: 17470383
   PubMed Web of Science ®Google Scholar
• Duechler M, Stańczyk M, Czyz M, Stepnik M. Potentiation of arsenic trioxide cytotoxicity by Parthenolide and buthionine sulfoximine in murine and human leukemic cells. Cancer Chemother Pharmacol 2008; 61:727 - 37; http://dx.doi.org/10.1007/s00280-007-0527-3; PMID: 17594095
   PubMed Web of Science ®Google Scholar
• Suvannasankha A, Crean CD, Shanmugam R, Farag SS, Abonour R, Boswell HS, et al. Antimyeloma effects of a sesquiterpene lactone parthenolide. Clin Cancer Res 2008; 14:1814 - 22; http://dx.doi.org/10.1158/1078-0432.CCR-07-1359; PMID: 18347184
   PubMed Web of Science ®Google Scholar
• Dai Y, Guzman ML, Chen S, Wang L, Yeung SK, Pei XY, et al. The NF (Nuclear factor)-κB inhibitor parthenolide interacts with histone deacetylase inhibitors to induce MKK7/JNK1-dependent apoptosis in human acute myeloid leukaemia cells. Br J Haematol 2010; 151:70 - 83; http://dx.doi.org/10.1111/j.1365-2141.2010.08319.x; PMID: 20701602
   PubMed Web of Science ®Google Scholar
• Czyz M, Lesiak-Mieczkowska K, Koprowska K, Szulawska-Mroczek A, Wozniak M. Cell context-dependent activities of parthenolide in primary and metastatic melanoma cells. Br J Pharmacol 2010; 160:1144 - 57; http://dx.doi.org/10.1111/j.1476-5381.2010.00749.x; PMID: 20590608
   PubMed Web of Science ®Google Scholar
• Lesiak K, Koprowska K, Zalesna I, Nejc D, Düchler M, Czyz M. Parthenolide, a sesquiterpene lactone from the medical herb feverfew, shows anticancer activity against human melanoma cells in vitro. Melanoma Res 2010; 20:21 - 34; http://dx.doi.org/10.1097/CMR.0b013e328333bbe4; PMID: 19949351
   PubMed Web of Science ®Google Scholar
• Guzman ML, Rossi RM, Karnischky L, Li X, Peterson DR, Howard DS, et al. The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells. Blood 2005; 105:4163 - 9; http://dx.doi.org/10.1182/blood-2004-10-4135; PMID: 15687234
   PubMed Web of Science ®Google Scholar
• Gunn EJ, Williams JT, Huynh DT, Iannotti MJ, Han C, Barrios FJ, et al. The natural products parthenolide and andrographolide exhibit anti-cancer stem cell activity in multiple myeloma. Leuk Lymphoma 2011; 52:1085 - 97; http://dx.doi.org/10.3109/10428194.2011.555891; PMID: 21417826
   PubMed Web of Science ®Google Scholar
• Liu Y, Lu WL, Guo J, Du J, Li T, Wu JW, et al. A potential target associated with both cancer and cancer stem cells: a combination therapy for eradication of breast cancer using vinorelbine stealthy liposomes plus parthenolide stealthy liposomes. J Control Release 2008; 129:18 - 25; http://dx.doi.org/10.1016/j.jconrel.2008.03.022; PMID: 18466993
   PubMed Web of Science ®Google Scholar
• Zhou J, Zhang H, Gu P, Bai J, Margolick JB, Zhang Y. NF-kappaB pathway inhibitors preferentially inhibit breast cancer stem-like cells. Breast Cancer Res Treat 2008; 111:419 - 27; http://dx.doi.org/10.1007/s10549-007-9798-y; PMID: 17965935
   PubMed Web of Science ®Google Scholar
• Kawasaki BT, Hurt EM, Kalathur M, Duhagon MA, Milner JA, Kim YS, et al. Effects of the sesquiterpene lactone parthenolide on prostate tumor-initiating cells: An integrated molecular profiling approach. Prostate 2009; 69:827 - 37; http://dx.doi.org/10.1002/pros.20931; PMID: 19204913
   PubMed Web of Science ®Google Scholar
• Hassane DC, Sen S, Minhajuddin M, Rossi RM, Corbett CA, Balys M, et al. Chemical genomic screening reveals synergism between parthenolide and inhibitors of the PI-3 kinase and mTOR pathways. Blood 2010; 116:5983 - 90; http://dx.doi.org/10.1182/blood-2010-04-278044; PMID: 20889920
   PubMed Web of Science ®Google Scholar
• Zuch D, Giang AH, Shapovalov Y, Schwarz E, Rosier R, O'Keefe R, et al. Targeting radioresistant osteosarcoma cells with parthenolide. J Cell Biochem 2012; 113:1282 - 91; PMID: 22109788
   PubMed Web of Science ®Google Scholar
• Thurber AE, Douglas G, Sturm EC, Zabierowski SE, Smit DJ, Ramakrishnan SN, et al. Inverse expression states of the BRN2 and MITF transcription factors in melanoma spheres and tumour xenografts regulate the NOTCH pathway. Oncogene 2011; 30:3036 - 48; http://dx.doi.org/10.1038/onc.2011.33; PMID: 21358674
   PubMed Web of Science ®Google Scholar
• Chen KG, Valencia JC, Gillet JP, Hearing VJ, Gottesman MM. Involvement of ABC transporters in melanogenesis and the development of multidrug resistance of melanoma. Pigment Cell Melanoma Res 2009; 22:740 - 9; http://dx.doi.org/10.1111/j.1755-148X.2009.00630.x; PMID: 19725928
   PubMed Web of Science ®Google Scholar
• Schatton T, Murphy GF, Frank NY, Yamaura K, Waaga-Gasser AM, Gasser M, et al. Identification of cells initiating human melanomas. Nature 2008; 451:345 - 9; http://dx.doi.org/10.1038/nature06489; PMID: 18202660
   PubMed Web of Science ®Google Scholar
• Perego M, Tortoreto M, Tragni G, Mariani L, Deho P, Carbone A, et al. Heterogeneous phenotype of human melanoma cells with in vitro and in vivo features of tumor-initiating cells. J Invest Dermatol 2010; 130:1877 - 86; http://dx.doi.org/10.1038/jid.2010.69; PMID: 20376064
   PubMed Web of Science ®Google Scholar
• Keshet GI, Goldstein I, Itzhaki O, Cesarkas K, Shenhav L, Yakirevitch A, et al. MDR1 expression identifies human melanoma stem cells. Biochem Biophys Res Commun 2008; 368:930 - 6; http://dx.doi.org/10.1016/j.bbrc.2008.02.022; PMID: 18279661
   PubMed Web of Science ®Google Scholar
• Frank NY, Margaryan A, Huang Y, Schatton T, Waaga-Gasser AM, Gasser M, et al. ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma. Cancer Res 2005; 65:4320 - 33; http://dx.doi.org/10.1158/0008-5472.CAN-04-3327; PMID: 15899824
   PubMed Web of Science ®Google Scholar
• Maugeri-Saccà M, Vigneri P, De Maria R. Cancer stem cells and chemosensitivity. Clin Cancer Res 2011; 17:4942 - 7; http://dx.doi.org/10.1158/1078-0432.CCR-10-2538; PMID: 21622723
   PubMed Web of Science ®Google Scholar
• Creighton CJ, Li X, Landis M, Dixon JM, Neumeister VM, Sjolund A, et al. Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features. Proc Natl Acad Sci U S A 2009; 106:13820 - 5; http://dx.doi.org/10.1073/pnas.0905718106; PMID: 19666588
   PubMed Web of Science ®Google Scholar
• Yu F, Yao H, Zhu P, Zhang X, Pan Q, Gong C, et al. let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell 2007; 131:1109 - 23; http://dx.doi.org/10.1016/j.cell.2007.10.054; PMID: 18083101
   PubMed Web of Science ®Google Scholar
• Chartrain M, Riond J, Stennevin A, Vandenberghe I, Gomes B, Lamant L, et al. Melanoma chemotherapy leads to the selection of ABCB5-expressing cells. PLoS One 2012; 7:e36762; http://dx.doi.org/10.1371/journal.pone.0036762; PMID: 22675422
   PubMed Web of Science ®Google Scholar
• Kim YR, Eom JI, Kim SJ, Jeung HK, Cheong JW, Kim JS, et al. Myeloperoxidase expression as a potential determinant of parthenolide-induced apoptosis in leukemia bulk and leukemia stem cells. J Pharmacol Exp Ther 2010; 335:389 - 400; http://dx.doi.org/10.1124/jpet.110.169367; PMID: 20699435
   PubMed Web of Science ®Google Scholar
• Murphy JJ, Heptinstall S, Mitchell JR. Randomised double-blind placebo-controlled trial of feverfew in migraine prevention. Lancet 1988; 2:189 - 92; http://dx.doi.org/10.1016/S0140-6736(88)92289-1; PMID: 2899663
   PubMed Web of Science ®Google Scholar
• Curry EA 3rd, Murry DJ, Yoder C, Fife K, Armstrong V, Nakshatri H, et al. Phase I dose escalation trial of feverfew with standardized doses of parthenolide in patients with cancer. Invest New Drugs 2004; 22:299 - 305; http://dx.doi.org/10.1023/B:DRUG.0000026256.38560.be; PMID: 15122077
   PubMed Web of Science ®Google Scholar
• Hehner SP, Heinrich M, Bork PM, Vogt M, Ratter F, Lehmann V, et al. Sesquiterpene lactones specifically inhibit activation of NF-kappa B by preventing the degradation of I kappa B-alpha and I kappa B-beta. J Biol Chem 1998; 273:1288 - 97; http://dx.doi.org/10.1074/jbc.273.3.1288; PMID: 9430659
   PubMed Web of Science ®Google Scholar
• Kwok BH, Koh B, Ndubuisi MI, Elofsson M, Crews CM. The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IkappaB kinase. Chem Biol 2001; 8:759 - 66; http://dx.doi.org/10.1016/S1074-5521(01)00049-7; PMID: 11514225
   PubMed Web of Science ®Google Scholar
• Carlisi D, D’Anneo A, Angileri L, Lauricella M, Emanuele S, Santulli A, et al. Parthenolide sensitizes hepatocellular carcinoma cells to TRAIL by inducing the expression of death receptors through inhibition of STAT3 activation. J Cell Physiol 2011; 226:1632 - 41; http://dx.doi.org/10.1002/jcp.22494; PMID: 21413021
   PubMed Web of Science ®Google Scholar
• Sobota R, Szwed M, Kasza A, Bugno M, Kordula T. Parthenolide inhibits activation of signal transducers and activators of transcription (STATs) induced by cytokines of the IL-6 family. Biochem Biophys Res Commun 2000; 267:329 - 33; http://dx.doi.org/10.1006/bbrc.1999.1948; PMID: 10623619
   PubMed Web of Science ®Google Scholar
• Nakshatri H, Rice SE, Bhat-Nakshatri P. Antitumor agent parthenolide reverses resistance of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through sustained activation of c-Jun N-terminal kinase. Oncogene 2004; 23:7330 - 44; http://dx.doi.org/10.1038/sj.onc.1207995; PMID: 15286701
   PubMed Web of Science ®Google Scholar
• Gopal YN, Chanchorn E, Van Dyke MW. Parthenolide promotes the ubiquitination of MDM2 and activates p53 cellular functions. Mol Cancer Ther 2009; 8:552 - 62; http://dx.doi.org/10.1158/1535-7163.MCT-08-0661; PMID: 19276167
   PubMed Web of Science ®Google Scholar
• Gopal YN, Arora TS, Van Dyke MW. Parthenolide specifically depletes histone deacetylase 1 protein and induces cell death through ataxia telangiectasia mutated. Chem Biol 2007; 14:813 - 23; http://dx.doi.org/10.1016/j.chembiol.2007.06.007; PMID: 17656318
   PubMed Web of Science ®Google Scholar
• Liu Z, Liu S, Xie Z, Pavlovicz RE, Wu J, Chen P, et al. Modulation of DNA methylation by a sesquiterpene lactone parthenolide. J Pharmacol Exp Ther 2009; 329:505 - 14; http://dx.doi.org/10.1124/jpet.108.147934; PMID: 19201992
   PubMed Web of Science ®Google Scholar
• Zhou J, Zhang Y. Cancer stem cells: Models, mechanisms and implications for improved treatment. Cell Cycle 2008; 7:1360 - 70; http://dx.doi.org/10.4161/cc.7.10.5953; PMID: 18418062
   PubMed Web of Science ®Google Scholar
• Lin L, Liu Y, Li H, Li PK, Fuchs J, Shibata H, et al. Targeting colon cancer stem cells using a new curcumin analogue, GO-Y030. Br J Cancer 2011; 105:212 - 20; http://dx.doi.org/10.1038/bjc.2011.200; PMID: 21694723
   PubMed Web of Science ®Google Scholar
• Skalska J, Brookes PS, Nadtochiy SM, Hilchey SP, Jordan CT, Guzman ML, et al. Modulation of cell surface protein free thiols: a potential novel mechanism of action of the sesquiterpene lactone parthenolide. PLoS One 2009; 4:e8115; http://dx.doi.org/10.1371/journal.pone.0008115; PMID: 19956548
   PubMedGoogle Scholar
• García-Piñeres AJ, Castro V, Mora G, Schmidt TJ, Strunck E, Pahl HL, et al. Cysteine 38 in p65/NF-kappaB plays a crucial role in DNA binding inhibition by sesquiterpene lactones. J Biol Chem 2001; 276:39713 - 20; http://dx.doi.org/10.1074/jbc.M101985200; PMID: 11500489
   PubMed Web of Science ®Google Scholar
• Moitra K, Scally M, McGee K, Lancaster G, Gold B, Dean M. Molecular evolutionary analysis of ABCB5: the ancestral gene is a full transporter with potentially deleterious single nucleotide polymorphisms. PLoS One 2011; 6:e16318; http://dx.doi.org/10.1371/journal.pone.0016318; PMID: 21298007
   PubMedGoogle Scholar