Advanced search
Publication Cover
Cancer Biology & Therapy Volume 15, 2014 - Issue 6
Submit an article Journal homepage
1,072
Views
2
CrossRef citations to date
0
Altmetric
Journal Club

Low pH reprograms somatic murine cells into pluripotent stem cells

A novel technique with therapeutic implications

Jonathan S Williams Dermatology Branch; Center for Cancer Research; National Cancer Institute; Bethesda, MD USA
,
Ying Xiao Dermatology Branch; Center for Cancer Research; National Cancer Institute; Bethesda, MD USA
&
Isaac Brownell Dermatology Branch; Center for Cancer Research; National Cancer Institute; Bethesda, MD USACorrespondence[email protected]
Pages 675-677 | Received 25 Feb 2014, Accepted 03 Mar 2014, Published online: 11 Mar 2014

References

  • Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006; 126:663 - 76; http://dx.doi.org/10.1016/j.cell.2006.07.024; PMID: 16904174
  • Okita K, Ichisaka T, Yamanaka S. Generation of germline-competent induced pluripotent stem cells. Nature 2007; 448:313 - 7; http://dx.doi.org/10.1038/nature05934; PMID: 17554338
  • Wernig M, Meissner A, Foreman R, Brambrink T, Ku M, Hochedlinger K, Bernstein BE, Jaenisch R. In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature 2007; 448:318 - 24; http://dx.doi.org/10.1038/nature05944; PMID: 17554336
  • Yu J, Vodyanik MA, Smuga-Otto K, Antosiewicz-Bourget J, Frane JL, Tian S, Nie J, Jonsdottir GA, Ruotti V, Stewart R, et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007; 318:1917 - 20; http://dx.doi.org/10.1126/science.1151526; PMID: 18029452
  • Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007; 131:861 - 72; http://dx.doi.org/10.1016/j.cell.2007.11.019; PMID: 18035408
  • Rajasingh J. Progress in molecular biology and translational science. Academic Press; c2012. Chapter 3, 51-82.
  • Obokata H, Wakayama T, Sasai Y, Kojima K, Vacanti MP, Niwa H, Yamato M, Vacanti CA. Stimulus-triggered fate conversion of somatic cells into pluripotency. Nature 2014; 505:641 - 7; http://dx.doi.org/10.1038/nature12968; PMID: 24476887
  • Cyranoski D. Acid bath offers easy path to stem cells. Nature 2014; 505:596; http://dx.doi.org/10.1038/505596a; PMID: 24476866
  • Themeli M, Kloss CC, Ciriello G, Fedorov VD, Perna F, Gonen M, Sadelain M. Generation of tumor-targeted human T lymphocytes from induced pluripotent stem cells for cancer therapy. Nat Biotechnol 2013; 31:928 - 33; http://dx.doi.org/10.1038/nbt.2678; PMID: 23934177
  • Wu R, Forget MA, Chacon J, Bernatchez C, Haymaker C, Chen JQ, Hwu P, Radvanyi LG. Adoptive T-cell therapy using autologous tumor-infiltrating lymphocytes for metastatic melanoma: current status and future outlook. Cancer J 2012; 18:160 - 75; http://dx.doi.org/10.1097/PPO.0b013e31824d4465; PMID: 22453018

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.