MiR-20a inhibits cutaneous squamous cell carcinoma metastasis and proliferation by directly targeting LIMK1

References

• Toll A, Masferrer E, Hernández-Ruiz ME, Ferrandiz-Pulido C, Yébenes M, Jaka A, Tuneu A, Jucglà A, Gimeno J, Baró T, et al. Epithelial to mesenchymal transition markers are associated with an increased metastatic risk in primary cutaneous squamous cell carcinomas but are attenuated in lymph node metastases. J Dermatol Sci 2013; 72:93 - 102; http://dx.doi.org/10.1016/j.jdermsci.2013.07.001; PMID: 23928229
   PubMed Web of Science ®Google Scholar
• Ya-ning JIAO, Li XIA, Xin-hong GE, Xiu-juan ZHANG, Jian-ping LIU, Li-peng WANG, Ling-di DONG, Nan YU, Xiao-ming Z. The Incidence Analysis of Skin Common Tumor from Five Hospitals in Ningxia from 2002 to 2011. The Chinese Journal of Dermatovenereology 2013; 36 - 8
   Google Scholar
• Gao TW, Sun DJ, Li CY, He H, Li Q, Liu YS, Diao QC, Huang GS, Hao F, Zhong BY, et al. [Retrospective analysis of 1905 patients with skin cancer from two general hospitals in western China from 1981 to 2000]. Beijing Da Xue Xue Bao 2004; 36:469 - 72; PMID: 15489924
   PubMedGoogle Scholar
• Rahimi S. Squamous cell carcinoma of skin: a brief review. Clin Ter 2013; 164:143 - 7; PMID: 23698209
   PubMed Web of Science ®Google Scholar
• Brougham ND, Dennett ER, Cameron R, Tan ST. The incidence of metastasis from cutaneous squamous cell carcinoma and the impact of its risk factors. J Surg Oncol 2012; 106:811 - 5; http://dx.doi.org/10.1002/jso.23155; PMID: 22592943
   PubMed Web of Science ®Google Scholar
• Schmults CD, Karia PS, Carter JB, Han J, Qureshi AA. Factors predictive of recurrence and death from cutaneous squamous cell carcinoma: a 10-year, single-institution cohort study. JAMA Dermatol 2013; 149:541 - 7; http://dx.doi.org/10.1001/jamadermatol.2013.2139; PMID: 23677079
   PubMed Web of Science ®Google Scholar
• Karia PS, Han J, Schmults CD. Cutaneous squamous cell carcinoma: estimated incidence of disease, nodal metastasis, and deaths from disease in the United States, 2012. J Am Acad Dermatol 2013; 68:957 - 66; http://dx.doi.org/10.1016/j.jaad.2012.11.037; PMID: 23375456
   PubMed Web of Science ®Google Scholar
• Song F, Qureshi AA, Giovannucci EL, Fuchs CS, Chen WY, Stampfer MJ, Han J. Risk of a second primary cancer after non-melanoma skin cancer in white men and women: a prospective cohort study. PLoS Med 2013; 10:e1001433; http://dx.doi.org/10.1371/journal.pmed.1001433; PMID: 23630459
   PubMedGoogle Scholar
• Johannesdottir SA, Lash TL, Jensen AO, Farkas DK, Olesen AB. Mortality in cancer patients with a history of cutaneous squamous cell carcinoma--a nationwide population-based cohort study. BMC Cancer 2012; 12:126; http://dx.doi.org/10.1186/1471-2407-12-126; PMID: 22458954
   PubMed Web of Science ®Google Scholar
• Lim LP, Lau NC, Garrett-Engele P, Grimson A, Schelter JM, Castle J, Bartel DP, Linsley PS, Johnson JM. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 2005; 433:769 - 73; http://dx.doi.org/10.1038/nature03315; PMID: 15685193
   PubMed Web of Science ®Google Scholar
• Kanitz A, Imig J, Dziunycz PJ, Primorac A, Galgano A, Hofbauer GF, Gerber AP, Detmar M. The expression levels of microRNA-361-5p and its target VEGFA are inversely correlated in human cutaneous squamous cell carcinoma. PLoS One 2012; 7:e49568; http://dx.doi.org/10.1371/journal.pone.0049568; PMID: 23166713
   PubMedGoogle Scholar
• Xu N, Zhang L, Meisgen F, Harada M, Heilborn J, Homey B, Grandér D, Ståhle M, Sonkoly E, Pivarcsi A. MicroRNA-125b down-regulates matrix metallopeptidase 13 and inhibits cutaneous squamous cell carcinoma cell proliferation, migration, and invasion. J Biol Chem 2012; 287:29899 - 908; http://dx.doi.org/10.1074/jbc.M112.391243; PMID: 22782903
   PubMed Web of Science ®Google Scholar
• Jung YJ, Kim JW, Park SJ, Min BY, Jang ES, Kim NY, Jeong SH, Shin CM, Lee SH, Park YS, et al. c-Myc-mediated overexpression of miR-17-92 suppresses replication of hepatitis B virus in human hepatoma cells. J Med Virol 2013; 85:969 - 78; http://dx.doi.org/10.1002/jmv.23534; PMID: 23532756
   PubMed Web of Science ®Google Scholar
• Li X, Zhang Z, Yu M, Li L, Du G, Xiao W, Yang H. Involvement of miR-20a in promoting gastric cancer progression by targeting early growth response 2 (EGR2). Int J Mol Sci 2013; 14:16226 - 39; http://dx.doi.org/10.3390/ijms140816226; PMID: 23924943
   PubMed Web of Science ®Google Scholar
• Chang Y, Liu C, Yang J, Liu G, Feng F, Tang J, Hu L, Li L, Jiang F, Chen C, et al. MiR-20a triggers metastasis of gallbladder carcinoma. J Hepatol 2013; 59:518 - 27; http://dx.doi.org/10.1016/j.jhep.2013.04.034; PMID: 23665284
   PubMed Web of Science ®Google Scholar
• miR-20a facilitates metastasis of osteosarcoma cells to lung tissue. Bonekey Rep 2012; 1:76; PMID: 23951469
   PubMedGoogle Scholar
• Yoshino H, Seki N, Itesako T, Chiyomaru T, Nakagawa M, Enokida H. Aberrant expression of microRNAs in bladder cancer. Nat Rev Urol 2013; 10:396 - 404; http://dx.doi.org/10.1038/nrurol.2013.113; PMID: 23712207
   PubMed Web of Science ®Google Scholar
• Li X, Pan JH, Song B, Xiong EQ, Chen ZW, Zhou ZS, Su YP. Suppression of CX43 expression by miR-20a in the progression of human prostate cancer. Cancer Biol Ther 2012; 13:890 - 8; http://dx.doi.org/10.4161/cbt.20841; PMID: 22785209
   PubMed Web of Science ®Google Scholar
• Zhao S, Yao DS, Chen JY, Ding N. Aberrant expression of miR-20a and miR-203 in cervical cancer. Asian Pac J Cancer Prev 2013; 14:2289 - 93; http://dx.doi.org/10.7314/APJCP.2013.14.4.2289; PMID: 23725129
   PubMed Web of Science ®Google Scholar
• Chang CC, Yang YJ, Li YJ, Chen ST, Lin BR, Wu TS, Lin SK, Kuo MY, Tan CT. MicroRNA-17/20a functions to inhibit cell migration and can be used a prognostic marker in oral squamous cell carcinoma. Oral Oncol 2013; 49:923 - 31; http://dx.doi.org/10.1016/j.oraloncology.2013.03.430; PMID: 23602254
   PubMed Web of Science ®Google Scholar
• Fan MQ, Huang CB, Gu Y, Xiao Y, Sheng JX, Zhong L. Decrease expression of microRNA-20a promotes cancer cell proliferation and predicts poor survival of hepatocellular carcinoma. Journal of experimental & clinical cancer research. CR (East Lansing, Mich) 2013; 32:21
   Google Scholar
• Dong Q, Ji YS, Cai C, Chen ZY. LIM kinase 1 (LIMK1) interacts with tropomyosin-related kinase B (TrkB) and Mediates brain-derived neurotrophic factor (BDNF)-induced axonal elongation. J Biol Chem 2012; 287:41720 - 31; http://dx.doi.org/10.1074/jbc.M112.405415; PMID: 23086941
   PubMed Web of Science ®Google Scholar
• Lindström NO, Neves C, McIntosh R, Miedzybrodzka Z, Vargesson N, Collinson JM. Tissue specific characterisation of Lim-kinase 1 expression during mouse embryogenesis. Gene Expr Patterns 2011; 11:221 - 32; http://dx.doi.org/10.1016/j.gep.2010.12.003; PMID: 21167960
   PubMed Web of Science ®Google Scholar
• Estevez B, Stojanovic-Terpo A, Delaney MK, O’Brien KA, Berndt MC, Ruan C, Du X. LIM kinase-1 selectively promotes glycoprotein Ib-IX-mediated TXA2 synthesis, platelet activation, and thrombosis. Blood 2013; 121:4586 - 94; http://dx.doi.org/10.1182/blood-2012-12-470765; PMID: 23620575
   PubMed Web of Science ®Google Scholar
• Nikitina EA, Medvedeva AV, Dolgaia IuF, Korochkin LI, Pavlova GV, Savvateeva-Popova EV. [Participation of GDNF, LIMK1 signal pathways and heat shock proteins in processes of Drosophila learning and memory formation]. Zh Evol Biokhim Fiziol 2012; 48:588 - 96; PMID: 23401971
   PubMedGoogle Scholar
• Li R, Doherty J, Antonipillai J, Chen S, Devlin M, Visser K, Baell J, Street I, Anderson RL, Bernard O. LIM kinase inhibition reduces breast cancer growth and invasiveness but systemic inhibition does not reduce metastasis in mice. Clin Exp Metastasis 2013; 30:483 - 95; http://dx.doi.org/10.1007/s10585-012-9553-6; PMID: 23239465
   PubMed Web of Science ®Google Scholar
• Zhang W, Gan N, Zhou J. Immunohistochemical investigation of the correlation between LIM kinase 1 expression and development and progression of human ovarian carcinoma. J Int Med Res 2012; 40:1067 - 73; http://dx.doi.org/10.1177/147323001204000325; PMID: 22906279
   PubMed Web of Science ®Google Scholar
• Zhang H, Wang Y, Xing F, Wang J, Wang Y, Wang H, Yang Y, Gao Z. Overexpression of LIMK1 promotes migration ability of multidrug-resistant osteosarcoma cells. Oncol Res 2011; 19:501 - 9; http://dx.doi.org/10.3727/096504012X13286534482511; PMID: 22715593
   PubMed Web of Science ®Google Scholar
• Roy P, Madan E, Kalra N, Nigam N, George J, Ray RS, Hans RK, Prasad S, Shukla Y. Resveratrol enhances ultraviolet B-induced cell death through nuclear factor-kappaB pathway in human epidermoid carcinoma A431 cells. Biochem Biophys Res Commun 2009; 384:215 - 20; http://dx.doi.org/10.1016/j.bbrc.2009.04.100; PMID: 19397895
   PubMed Web of Science ®Google Scholar
• Prasad S, Madan E, Nigam N, Roy P, George J, Shukla Y. Induction of apoptosis by lupeol in human epidermoid carcinoma A431 cells through regulation of mitochondrial, Akt/PKB and NFkappaB signaling pathways. Cancer Biol Ther 2009; 8:1632 - 9; http://dx.doi.org/10.4161/cbt.8.17.9204; PMID: 19625778
   PubMed Web of Science ®Google Scholar
• Ung N, Putoczki TL, Stylli SS, Ng I, Mariadason JM, Chan TA, Zhu HJ, Luwor RB. Anti-EGFR therapeutic efficacy correlates directly with inhibition of STAT3 activity. Cancer Biol Ther 2014; 15:623 - 32; http://dx.doi.org/10.4161/cbt.28179; PMID: 24556630
   PubMed Web of Science ®Google Scholar
• Wu D, Guo Z, Min W, Zhou B, Li M, Li W, Luo D. Upregulation of TCTP expression in human skin squamous cell carcinoma increases tumor cell viability through anti-apoptotic action of the protein. Exp Ther Med 2012; 3:437 - 42; PMID: 22969908
   PubMed Web of Science ®Google Scholar
• Xia YH, Li M, Fu DD, Xu SL, Li ZG, Liu D, Tian ZW. Effects of PTTG down-regulation on proliferation and metastasis of the SCL-1 cutaneous squamous cell carcinoma cell line. Asian Pac J Cancer Prev 2013; 14:6245 - 8; http://dx.doi.org/10.7314/APJCP.2013.14.11.6245; PMID: 24377512
   PubMed Web of Science ®Google Scholar
• Sand M, Skrygan M, Georgas D, Sand D, Hahn SA, Gambichler T, Altmeyer P, Bechara FG. Microarray analysis of microRNA expression in cutaneous squamous cell carcinoma. J Dermatol Sci 2012; 68:119 - 26; http://dx.doi.org/10.1016/j.jdermsci.2012.09.004; PMID: 23026055
   PubMed Web of Science ®Google Scholar
• Gastaldi C, Bertero T, Xu N, Bourget-Ponzio I, Lebrigand K, Fourre S, Popa A, Cardot-Leccia N, Meneguzzi G, Sonkoly E, et al. miR-193b/365a cluster controls progression of epidermal squamous cell carcinoma. Carcinogenesis 2014; 35:1110 - 20; http://dx.doi.org/10.1093/carcin/bgt490; PMID: 24374827
   PubMed Web of Science ®Google Scholar
• Bertero T, Bourget-Ponzio I, Puissant A, Loubat A, Mari B, Meneguzzi G, Auberger P, Barbry P, Ponzio G, Rezzonico R. Tumor suppressor function of miR-483-3p on squamous cell carcinomas due to its pro-apoptotic properties. Cell Cycle 2013; 12:2183 - 93; http://dx.doi.org/10.4161/cc.25330; PMID: 24067364
   PubMed Web of Science ®Google Scholar
• Zhou M, Liu W, Ma S, Cao H, Peng X, Guo L, Zhou X, Zheng L, Guo L, Wan M, et al. A novel onco-miR-365 induces cutaneous squamous cell carcinoma. Carcinogenesis 2013; 34:1653 - 9; http://dx.doi.org/10.1093/carcin/bgt097; PMID: 23514750
   PubMed Web of Science ®Google Scholar
• Olive V, Jiang I, He L. mir-17-92, a cluster of miRNAs in the midst of the cancer network. Int J Biochem Cell Biol 2010; 42:1348 - 54; http://dx.doi.org/10.1016/j.biocel.2010.03.004; PMID: 20227518
   PubMed Web of Science ®Google Scholar
• Chen J, Yao D, Li Y, Chen H, He C, Ding N, Lu Y, Ou T, Zhao S, Li L, et al. Serum microRNA expression levels can predict lymph node metastasis in patients with early-stage cervical squamous cell carcinoma. Int J Mol Med 2013; 32:557 - 67; PMID: 23799609
   PubMed Web of Science ®Google Scholar
• Liu R, Liao J, Yang M, Shi Y, Peng Y, Wang Y, Pan E, Guo W, Pu Y, Yin L. Circulating miR-155 expression in plasma: a potential biomarker for early diagnosis of esophageal cancer in humans. J Toxicol Environ Health A 2012; 75:1154 - 62; http://dx.doi.org/10.1080/15287394.2012.699856; PMID: 22891887
   PubMed Web of Science ®Google Scholar
• Scott RW, Hooper S, Crighton D, Li A, König I, Munro J, Trivier E, Wickman G, Morin P, Croft DR, et al. LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells. J Cell Biol 2010; 191:169 - 85; http://dx.doi.org/10.1083/jcb.201002041; PMID: 20876278
   PubMed Web of Science ®Google Scholar
• Jang I, Jeon BT, Jeong EA, Kim EJ, Kang D, Lee JS, Jeong BG, Kim JH, Choi BH, Lee JE, et al. Pak1/LIMK1/Cofilin Pathway Contributes to Tumor Migration and Invasion in Human Non-Small Cell Lung Carcinomas and Cell Lines. Korean J Physiol Pharmacol 2012; 16:159 - 65; http://dx.doi.org/10.4196/kjpp.2012.16.3.159; PMID: 22802696
   PubMed Web of Science ®Google Scholar