957
Views
21
CrossRef citations to date
0
Altmetric
Review

Identification of novel metastasis suppressor signaling pathways for breast cancer

, , &
Pages 2452-2457 | Published online: 01 Jul 2012

References

  • Bozic I, Antal T, Ohtsuki H, Carter H, Kim D, Chen S, et al. Accumulation of driver and passenger mutations during tumor progression. Proc Natl Acad Sci USA 2010; 107:18545 - 50; http://dx.doi.org/10.1073/pnas.1010978107; PMID: 20876136
  • Jones S, Zhang X, Parsons DW, Lin JC, Leary RJ, Angenendt P, et al. Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science 2008; 321:1801 - 6; http://dx.doi.org/10.1126/science.1164368; PMID: 18772397
  • Wood LD, Parsons DW, Jones S, Lin J, Sjöblom T, Leary RJ, et al. The genomic landscapes of human breast and colorectal cancers. Science 2007; 318:1108 - 13; http://dx.doi.org/10.1126/science.1145720; PMID: 17932254
  • Kang Y, Siegel PM, Shu W, Drobnjak M, Kakonen SM, Cordón-Cardo C, et al. A multigenic program mediating breast cancer metastasis to bone. Cancer Cell 2003; 3:537 - 49; http://dx.doi.org/10.1016/S1535-6108(03)00132-6; PMID: 12842083
  • Minn AJ, Gupta GP, Siegel PM, Bos PD, Shu W, Giri DD, et al. Genes that mediate breast cancer metastasis to lung. Nature 2005; 436:518 - 24; http://dx.doi.org/10.1038/nature03799; PMID: 16049480
  • Gupta GP, Nguyen DX, Chiang AC, Bos PD, Kim JY, Nadal C, et al. Mediators of vascular remodelling co-opted for sequential steps in lung metastasis. Nature 2007; 446:765 - 70; http://dx.doi.org/10.1038/nature05760; PMID: 17429393
  • Gupta GP, Perk J, Acharyya S, de Candia P, Mittal V, Todorova-Manova K, et al. ID genes mediate tumor reinitiation during breast cancer lung metastasis. Proc Natl Acad Sci USA 2007; 104:19506 - 11; http://dx.doi.org/10.1073/pnas.0709185104; PMID: 18048329
  • Oskarsson T, Acharyya S, Zhang XH, Vanharanta S, Tavazoie SF, Morris PG, et al. Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs. Nat Med 2011; 17:867 - 74; http://dx.doi.org/10.1038/nm.2379; PMID: 21706029
  • Chen Q, Zhang XH, Massagué J. Macrophage binding to receptor VCAM-1 transmits survival signals in breast cancer cells that invade the lungs. Cancer Cell 2011; 20:538 - 49; http://dx.doi.org/10.1016/j.ccr.2011.08.025; PMID: 22014578
  • Han HJ, Russo J, Kohwi Y, Kohwi-Shigematsu T. SATB1 reprogrammes gene expression to promote breast tumour growth and metastasis. Nature 2008; 452:187 - 93; http://dx.doi.org/10.1038/nature06781; PMID: 18337816
  • Tavazoie SF, Alarcón C, Oskarsson T, Padua D, Wang Q, Bos PD, et al. Endogenous human microRNAs that suppress breast cancer metastasis. Nature 2008; 451:147 - 52; http://dx.doi.org/10.1038/nature06487; PMID: 18185580
  • Gupta RA, Shah N, Wang KC, Kim J, Horlings HM, Wong DJ, et al. Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature 2010; 464:1071 - 6; http://dx.doi.org/10.1038/nature08975; PMID: 20393566
  • Ma L, Weinberg RA. Micromanagers of malignancy: role of microRNAs in regulating metastasis. Trends Genet 2008; 24:448 - 56; http://dx.doi.org/10.1016/j.tig.2008.06.004; PMID: 18674843
  • Nguyen DX, Chiang AC, Zhang XH, Kim JY, Kris MG, Ladanyi M, et al. WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis. Cell 2009; 138:51 - 62; http://dx.doi.org/10.1016/j.cell.2009.04.030; PMID: 19576624
  • Valastyan S, Reinhardt F, Benaich N, Calogrias D, Szász AM, Wang ZC, et al. A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell 2009; 137:1032 - 46; http://dx.doi.org/10.1016/j.cell.2009.03.047; PMID: 19524507
  • Zhang XH, Wang Q, Gerald W, Hudis CA, Norton L, Smid M, et al. Latent bone metastasis in breast cancer tied to Src-dependent survival signals. Cancer Cell 2009; 16:67 - 78; http://dx.doi.org/10.1016/j.ccr.2009.05.017; PMID: 19573813
  • Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 2005; 102:15545 - 50; http://dx.doi.org/10.1073/pnas.0506580102; PMID: 16199517
  • Huynh-Thu VA, Irrthum A, Wehenkel L, Geurts P. Inferring regulatory networks from expression data using tree-based methods. PLoS ONE 2010; 5:pii: e12776; http://dx.doi.org/10.1371/journal.pone.0012776; PMID: 20927193
  • Ideker T, Dutkowski J, Hood L. Boosting signal-to-noise in complex biology: prior knowledge is power. Cell 2011; 144:860 - 3; http://dx.doi.org/10.1016/j.cell.2011.03.007; PMID: 21414478
  • Efron B, Tibshirani R. On testing the significance of sets of genes. Annals of Applied Statistics 2007; 1:107 - 29; http://dx.doi.org/10.1214/07-AOAS101
  • Breiman L. Random Forests. Mach Learn 2001; 45:5 - 32; http://dx.doi.org/10.1023/A:1010933404324
  • Dangi-Garimella S, Yun J, Eves EM, Newman M, Erkeland SJ, Hammond SM, et al. Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7. EMBO J 2009; 28:347 - 58; http://dx.doi.org/10.1038/emboj.2008.294; PMID: 19153603
  • Granovsky AE, Rosner MR. Raf kinase inhibitory protein: a signal transduction modulator and metastasis suppressor. Cell Res 2008; 18:452 - 7; http://dx.doi.org/10.1038/cr.2008.43; PMID: 18379591
  • Corbit KC, Trakul N, Eves EM, Diaz B, Marshall M, Rosner MR. Activation of Raf-1 signaling by protein kinase C through a mechanism involving Raf kinase inhibitory protein. J Biol Chem 2003; 278:13061 - 8; http://dx.doi.org/10.1074/jbc.M210015200; PMID: 12551925
  • Trakul N, Menard RE, Schade GR, Qian Z, Rosner MR. Raf kinase inhibitory protein regulates Raf-1 but not B-Raf kinase activation. J Biol Chem 2005; 280:24931 - 40; http://dx.doi.org/10.1074/jbc.M413929200; PMID: 15886202
  • Lorenz K, Lohse MJ, Quitterer U. Protein kinase C switches the Raf kinase inhibitor from Raf-1 to GRK-2. Nature 2003; 426:574 - 9; http://dx.doi.org/10.1038/nature02158; PMID: 14654844
  • Yeung KC, Rose DW, Dhillon AS, Yaros D, Gustafsson M, Chatterjee D, et al. Raf kinase inhibitor protein interacts with NF-kappaB-inducing kinase and TAK1 and inhibits NF-kappaB activation. Mol Cell Biol 2001; 21:7207 - 17; http://dx.doi.org/10.1128/MCB.21.21.7207-7217.2001; PMID: 11585904
  • Eves EM, Shapiro P, Naik K, Klein UR, Trakul N, Rosner MR. Raf kinase inhibitory protein regulates aurora B kinase and the spindle checkpoint. Mol Cell 2006; 23:561 - 74; http://dx.doi.org/10.1016/j.molcel.2006.07.015; PMID: 16916643
  • Akaishi J, Onda M, Asaka S, Okamoto J, Miyamoto S, Nagahama M, et al. Growth-suppressive function of phosphatidylethanolamine-binding protein in anaplastic thyroid cancer. Anticancer Res 2006; 26:6B 4437 - 42; PMID: 17201166
  • Al-Mulla F, Hagan S, Behbehani AI, Bitar MS, George SS, Going JJ, et al. Raf kinase inhibitor protein expression in a survival analysis of colorectal cancer patients. J Clin Oncol 2006; 24:5672 - 9; http://dx.doi.org/10.1200/JCO.2006.07.5499; PMID: 17179102
  • Fu Z, Kitagawa Y, Shen R, Shah R, Mehra R, Rhodes D, et al. Metastasis suppressor gene Raf kinase inhibitor protein (RKIP) is a novel prognostic marker in prostate cancer. Prostate 2006; 66:248 - 56; http://dx.doi.org/10.1002/pros.20319; PMID: 16175585
  • Fu Z, Smith PC, Zhang L, Rubin MA, Dunn RL, Yao Z, et al. Effects of raf kinase inhibitor protein expression on suppression of prostate cancer metastasis. J Natl Cancer Inst 2003; 95:878 - 89; http://dx.doi.org/10.1093/jnci/95.12.878; PMID: 12813171
  • Hagan S, Al-Mulla F, Mallon E, Oien K, Ferrier R, Gusterson B, et al. Reduction of Raf-1 kinase inhibitor protein expression correlates with breast cancer metastasis. Clin Cancer Res 2005; 11:7392 - 7; http://dx.doi.org/10.1158/1078-0432.CCR-05-0283; PMID: 16243812
  • Schuierer MM, Bataille F, Hagan S, Kolch W, Bosserhoff AK. Reduction in Raf kinase inhibitor protein expression is associated with increased Ras-extracellular signal-regulated kinase signaling in melanoma cell lines. Cancer Res 2004; 64:5186 - 92; http://dx.doi.org/10.1158/0008-5472.CAN-03-3861; PMID: 15289323
  • Yun J, Frankenberger CA, Kuo WL, Boelens MC, Eves EM, Cheng N, et al. Signalling pathway for RKIP and Let-7 regulates and predicts metastatic breast cancer. EMBO J 2011; 30:4500 - 14; http://dx.doi.org/10.1038/emboj.2011.312; PMID: 21873975
  • Park SM, Shell S, Radjabi AR, Schickel R, Feig C, Boyerinas B, et al. Let-7 prevents early cancer progression by suppressing expression of the embryonic gene HMGA2. Cell Cycle 2007; 6:2585 - 90; http://dx.doi.org/10.4161/cc.6.21.4845; PMID: 17957144
  • Bevilacqua E, Frankenberger CA, Rosner MR. RKIP Suppresses Breast Cancer Metastasis to the Bone by Regulating Stroma-Associated Genes. Int J Breast Cancer 2012; 2012:124704; http://dx.doi.org/10.1155/2012/124704; PMID: 22482058

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.