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Induction of ASAP (MAP9) contributes to p53 stabilization in response to DNA damage

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Pages 2380-2390 | Published online: 15 Jun 2012

References

  • Vousden KH, Prives C. Blinded by the Light: The Growing Complexity of p53. Cell 2009; 137:413 - 31; http://dx.doi.org/10.1016/j.cell.2009.04.037; PMID: 19410540
  • Kruse JP, Gu W. Modes of p53 regulation. Cell 2009; 137:609 - 22; http://dx.doi.org/10.1016/j.cell.2009.04.050; PMID: 19450511
  • Brooks CL, Gu W. p53 ubiquitination: Mdm2 and beyond. Mol Cell 2006; 21:307 - 15; http://dx.doi.org/10.1016/j.molcel.2006.01.020; PMID: 16455486
  • Marine JC, Francoz S, Maetens M, Wahl G, Toledo F, Lozano G. Keeping p53 in check: essential and synergistic functions of Mdm2 and Mdm4. Cell Death Differ 2006; 13:927 - 34; http://dx.doi.org/10.1038/sj.cdd.4401912; PMID: 16543935
  • Oren M. Decision making by p53: life, death and cancer. Cell Death Differ 2003; 10:431 - 42; http://dx.doi.org/10.1038/sj.cdd.4401183; PMID: 12719720
  • Toledo F, Wahl GM. Regulating the p53 pathway: in vitro hypotheses, in vivo veritas. Nat Rev Cancer 2006; 6:909 - 23; http://dx.doi.org/10.1038/nrc2012; PMID: 17128209
  • Tang Y, Zhao W, Chen Y, Zhao Y, Gu W. Acetylation is indispensable for p53 activation. Cell 2008; 133:612 - 26; http://dx.doi.org/10.1016/j.cell.2008.03.025; PMID: 18485870
  • Teufel DP, Bycroft M, Fersht AR. Regulation by phosphorylation of the relative affinities of the N-terminal transactivation domains of p53 for p300 domains and Mdm2. Oncogene 2009; 28:2112 - 8; http://dx.doi.org/10.1038/onc.2009.71; PMID: 19363523
  • Ferreon JC, Lee CW, Arai M, Martinez-Yamout MA, Dyson HJ, Wright PE. Cooperative regulation of p53 by modulation of ternary complex formation with CBP/p300 and HDM2. Proc Natl Acad Sci USA 2009; 106:6591 - 6; http://dx.doi.org/10.1073/pnas.0811023106; PMID: 19357310
  • Saffin JM, Venoux M, Prigent C, Espeut J, Poulat F, Giorgi D, et al. ASAP, a human microtubule-associated protein required for bipolar spindle assembly and cytokinesis. Proc Natl Acad Sci USA 2005; 102:11302 - 7; http://dx.doi.org/10.1073/pnas.0500964102; PMID: 16049101
  • Venoux M, Basbous J, Berthenet C, Prigent C, Fernandez A, Lamb NJ, et al. ASAP is a novel substrate of the oncogenic mitotic kinase Aurora-A: phosphorylation on Ser625 is essential to spindle formation and mitosis. Hum Mol Genet 2008; 17:215 - 24; http://dx.doi.org/10.1093/hmg/ddm298; PMID: 17925329
  • Venoux M, Delmouly K, Milhavet O, Vidal-Eychenié S, Giorgi D, Rouquier S. Gene organization, evolution and expression of the microtubule-associated protein ASAP (MAP9). BMC Genomics 2008; 9:406; http://dx.doi.org/10.1186/1471-2164-9-406; PMID: 18782428
  • Yu X, Chini CC, He M, Mer G, Chen J. The BRCT domain is a phospho-protein binding domain. Science 2003; 302:639 - 42; http://dx.doi.org/10.1126/science.1088753; PMID: 14576433
  • Gu W, Roeder RG. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell 1997; 90:595 - 606; http://dx.doi.org/10.1016/S0092-8674(00)80521-8; PMID: 9288740
  • Michael D, Oren M. The p53-Mdm2 module and the ubiquitin system. Semin Cancer Biol 2003; 13:49 - 58; http://dx.doi.org/10.1016/S1044-579X(02)00099-8; PMID: 12507556
  • Poyurovsky MV, Katz C, Laptenko O, Beckerman R, Lokshin M, Ahn J, et al. The C terminus of p53 binds the N-terminal domain of MDM2. Nat Struct Mol Biol 2010; 17:982 - 9; http://dx.doi.org/10.1038/nsmb.1872; PMID: 20639885
  • Cheng Q, Chen J. The phenotype of MDM2 auto-degradation after DNA damage is due to epitope masking by phosphorylation. Cell Cycle 2011; 10:1162 - 6; http://dx.doi.org/10.4161/cc.10.7.15249; PMID: 21386656
  • Shiloh Y. ATM and related protein kinases: safeguarding genome integrity. Nat Rev Cancer 2003; 3:155 - 68; http://dx.doi.org/10.1038/nrc1011; PMID: 12612651
  • Eot-Houllier G, Venoux M, Vidal-Eychenié S, Hoang MT, Giorgi D, Rouquier S. Plk1 regulates both ASAP localization and its role in spindle pole integrity. J Biol Chem 2010; 285:29556 - 68; http://dx.doi.org/10.1074/jbc.M110.144220; PMID: 20615875
  • Ducat D, Kawaguchi S, Liu H, Yates JR 3rd, Zheng Y. Regulation of microtubule assembly and organization in mitosis by the AAA+ ATPase Pontin. Mol Biol Cell 2008; 19:3097 - 110; http://dx.doi.org/10.1091/mbc.E07-11-1202; PMID: 18463163
  • Joukov V, Groen AC, Prokhorova T, Gerson R, White E, Rodriguez A, et al. The BRCA1/BARD1 heterodimer modulates ran-dependent mitotic spindle assembly. Cell 2006; 127:539 - 52; http://dx.doi.org/10.1016/j.cell.2006.08.053; PMID: 17081976
  • Parvin JD, Sankaran S. The BRCA1 E3 ubiquitin ligase controls centrosome dynamics. Cell Cycle 2006; 5:1946 - 50; http://dx.doi.org/10.4161/cc.5.17.3208; PMID: 16969086
  • Löffler H, Lukas J, Bartek J, Krämer A. Structure meets function--centrosomes, genome maintenance and the DNA damage response. Exp Cell Res 2006; 312:2633 - 40; http://dx.doi.org/10.1016/j.yexcr.2006.06.008; PMID: 16854412
  • Smith E, Dejsuphong D, Balestrini A, Hampel M, Lenz C, Takeda S, et al. An ATM- and ATR-dependent checkpoint inactivates spindle assembly by targeting CEP63. Nat Cell Biol 2009; 11:278 - 85; http://dx.doi.org/10.1038/ncb1835; PMID: 19182792
  • Freire R, van Vugt MA, Mamely I, Medema RH. Claspin: timing the cell cycle arrest when the genome is damaged. Cell Cycle 2006; 5:2831 - 4; http://dx.doi.org/10.4161/cc.5.24.3559; PMID: 17172868
  • Mamely I, van Vugt MA, Smits VA, Semple JI, Lemmens B, Perrakis A, et al. Polo-like kinase-1 controls proteasome-dependent degradation of Claspin during checkpoint recovery. Curr Biol 2006; 16:1950 - 5; http://dx.doi.org/10.1016/j.cub.2006.08.026; PMID: 16934469
  • Kasper LH, Thomas MC, Zambetti GP, Brindle PK. Double null cells reveal that CBP and p300 are dispensable for p53 targets p21 and Mdm2 but variably required for target genes of other signaling pathways. Cell Cycle 2011; 10:212 - 21; http://dx.doi.org/10.4161/cc.10.2.14542; PMID: 21220944
  • Carter S, Vousden KH. Modifications of p53: competing for the lysines. Curr Opin Genet Dev 2009; 19:18 - 24; http://dx.doi.org/10.1016/j.gde.2008.11.010; PMID: 19179064
  • Coutts AS, Adams CJ, La Thangue NB. p53 ubiquitination by Mdm2: a never ending tail?. DNA Repair (Amst) 2009; 8:483 - 90; http://dx.doi.org/10.1016/j.dnarep.2009.01.008; PMID: 19217357
  • Azmi AS, Banerjee S, Ali S, Wang Z, Bao B, Beck FW, et al. Network modeling of MDM2 inhibitor-oxaliplatin combination reveals biological synergy in wt-p53 solid tumors. Oncotarget 2011; 2:378 - 92; PMID: 21623005
  • Knappskog S, Lønning PE. MDM2 promoter SNP285 and SNP309; phylogeny and impact on cancer risk. Oncotarget 2011; 2:251 - 8; PMID: 21436469
  • Dai MS, Sun XX, Lu H. Aberrant expression of nucleostemin activates p53 and induces cell cycle arrest via inhibition of MDM2. Mol Cell Biol 2008; 28:4365 - 76; http://dx.doi.org/10.1128/MCB.01662-07; PMID: 18426907
  • Miliani de Marval PL, Zhang Y. The RP-Mdm2-p53 pathway and tumorigenesis. Oncotarget 2011; 2:234 - 8; PMID: 21406728
  • Llanos S, Serrano M. Depletion of ribosomal protein L37 occurs in response to DNA damage and activates p53 through the L11/MDM2 pathway. Cell Cycle 2010; 9:4005 - 12; http://dx.doi.org/10.4161/cc.9.19.13299; PMID: 20935493
  • Roe JS, Kim H, Lee SM, Kim ST, Cho EJ, Youn HD. p53 stabilization and transactivation by a von Hippel-Lindau protein. Mol Cell 2006; 22:395 - 405; http://dx.doi.org/10.1016/j.molcel.2006.04.006; PMID: 16678111
  • Song MS, Song SJ, Kim SY, Oh HJ, Lim DS. The tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2-DAXX-HAUSP complex. EMBO J 2008; 27:1863 - 74; http://dx.doi.org/10.1038/emboj.2008.115; PMID: 18566590
  • Fumoto K, Kadono M, Izumi N, Kikuchi A. Axin localizes to the centrosome and is involved in microtubule nucleation. EMBO Rep 2009; 10:606 - 13; http://dx.doi.org/10.1038/embor.2009.45; PMID: 19390532
  • Li Q, Lin S, Wang X, Lian G, Lu Z, Guo H, et al. Axin determines cell fate by controlling the p53 activation threshold after DNA damage. Nat Cell Biol 2009; 11:1128 - 34; http://dx.doi.org/10.1038/ncb1927; PMID: 19731416
  • Coutts AS, Weston L, La Thangue NB. A transcription co-factor integrates cell adhesion and motility with the p53 response. Proc Natl Acad Sci USA 2009; 106:19872 - 7; PMID: 19897726
  • Coutts AS, Weston L, La Thangue NB. Actin nucleation by a transcription co-factor that links cytoskeletal events with the p53 response. Cell Cycle 2010; 9:1511 - 5; http://dx.doi.org/10.4161/cc.9.8.11258; PMID: 20372063
  • Abe Y, Ohsugi M, Haraguchi K, Fujimoto J, Yamamoto T. LATS2-Ajuba complex regulates gamma-tubulin recruitment to centrosomes and spindle organization during mitosis. FEBS Lett 2006; 580:782 - 8; http://dx.doi.org/10.1016/j.febslet.2005.12.096; PMID: 16413547
  • Aylon Y, Michael D, Shmueli A, Yabuta N, Nojima H, Oren M. A positive feedback loop between the p53 and Lats2 tumor suppressors prevents tetraploidization. Genes Dev 2006; 20:2687 - 700; http://dx.doi.org/10.1101/gad.1447006; PMID: 17015431
  • Rong R, Jiang LY, Sheikh MS, Huang Y. Mitotic kinase Aurora-A phosphorylates RASSF1A and modulates RASSF1A-mediated microtubule interaction and M-phase cell cycle regulation. Oncogene 2007; 26:7700 - 8; http://dx.doi.org/10.1038/sj.onc.1210575; PMID: 17563743
  • Toji S, Yabuta N, Hosomi T, Nishihara S, Kobayashi T, Suzuki S, et al. The centrosomal protein Lats2 is a phosphorylation target of Aurora-A kinase. Genes Cells 2004; 9:383 - 97; http://dx.doi.org/10.1111/j.1356-9597.2004.00732.x; PMID: 15147269
  • Katayama H, Sasai K, Kawai H, Yuan ZM, Bondaruk J, Suzuki F, et al. Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53. Nat Genet 2004; 36:55 - 62; http://dx.doi.org/10.1038/ng1279; PMID: 14702041
  • Zhou R, Bonneaud N, Yuan CX, de Santa Barbara P, Boizet B, Schomber T, et al. SOX9 interacts with a component of the human thyroid hormone receptor-associated protein complex. Nucleic Acids Res 2002; 30:3245 - 52; http://dx.doi.org/10.1093/nar/gkf443; PMID: 12136106
  • Fromont-Racine M, Rain JC, Legrain P. Toward a functional analysis of the yeast genome through exhaustive two-hybrid screens. Nat Genet 1997; 16:277 - 82; http://dx.doi.org/10.1038/ng0797-277; PMID: 9207794
  • Le Cam L, Linares LK, Paul C, Julien E, Lacroix M, Hatchi E, et al. E4F1 is an atypical ubiquitin ligase that modulates p53 effector functions independently of degradation. Cell 2006; 127:775 - 88; http://dx.doi.org/10.1016/j.cell.2006.09.031; PMID: 17110336

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