Independent transcriptional reprogramming and apoptosis induction by cisplatin

References

• Kelland L. The resurgence of platinum-based cancer chemotherapy. Nat Rev Cancer 2007; 7:573 - 84; http://dx.doi.org/10.1038/nrc2167; PMID: 17625587
   PubMed Web of Science ®Google Scholar
• Nardella C, Clohessy JG, Alimonti A, Pandolfi PP. Pro-senescence therapy for cancer treatment. Nat Rev Cancer 2011; 11:503 - 11; http://dx.doi.org/10.1038/nrc3057; PMID: 21701512
   PubMed Web of Science ®Google Scholar
• Kroemer G, Galluzzi L, Brenner C. Mitochondrial membrane permeabilization in cell death. Physiol Rev 2007; 87:99 - 163; http://dx.doi.org/10.1152/physrev.00013.2006; PMID: 17237344
   PubMed Web of Science ®Google Scholar
• Mandic A, Hansson J, Linder S, Shoshan MC. Cisplatin induces endoplasmic reticulum stress and nucleus-independent apoptotic signaling. J Biol Chem 2003; 278:9100 - 6; http://dx.doi.org/10.1074/jbc.M210284200; PMID: 12509415
   PubMed Web of Science ®Google Scholar
• Berndtsson M, Hägg M, Panaretakis T, Havelka AM, Shoshan MC, Linder S. Acute apoptosis by cisplatin requires induction of reactive oxygen species but is not associated with damage to nuclear DNA. Int J Cancer 2007; 120:175 - 80; http://dx.doi.org/10.1002/ijc.22132; PMID: 17044026
   PubMed Web of Science ®Google Scholar
• Gonzalez VM, Fuertes MA, Alonso C, Perez JM. Is cisplatin-induced cell death always produced by apoptosis?. Mol Pharmacol 2001; 59:657 - 63; PMID: 11259608
   PubMed Web of Science ®Google Scholar
• Tajeddine N, Galluzzi L, Kepp O, Hangen E, Morselli E, Senovilla L, et al. Hierarchical involvement of Bak, VDAC1 and Bax in cisplatin-induced cell death. Oncogene 2008; 27:4221 - 32; http://dx.doi.org/10.1038/onc.2008.63; PMID: 18362892
   PubMed Web of Science ®Google Scholar
• Castedo M, Coquelle A, Vivet S, Vitale I, Kauffmann A, Dessen P, et al. Apoptosis regulation in tetraploid cancer cells. EMBO J 2006; 25:2584 - 95; http://dx.doi.org/10.1038/sj.emboj.7601127; PMID: 16675948
   PubMed Web of Science ®Google Scholar
• Winter C, Albers P. Testicular germ cell tumors: pathogenesis, diagnosis and treatment. Nat Rev Endocrinol 2011; 7:43 - 53; http://dx.doi.org/10.1038/nrendo.2010.196; PMID: 21116298
   PubMed Web of Science ®Google Scholar
• Galluzzi L, Senovilla L, Vitale I, Michels J, Martins I, Kepp O, et al. Molecular mechanisms of cisplatin resistance. Oncogene 2012; 31:1869 - 83; http://dx.doi.org/10.1038/onc.2011.384; PMID: 21892204
   PubMed Web of Science ®Google Scholar
• Köberle B, Tomicic MT, Usanova S, Kaina B. Cisplatin resistance: preclinical findings and clinical implications. Biochim Biophys Acta 2010; 1806:172 - 82; PMID: 20647037
   PubMed Web of Science ®Google Scholar
• Siddik ZH. Cisplatin: mode of cytotoxic action and molecular basis of resistance. Oncogene 2003; 22:7265 - 79; http://dx.doi.org/10.1038/sj.onc.1206933; PMID: 14576837
   PubMed Web of Science ®Google Scholar
• Beers MH. Lung carcinoma. In: Porter RS, Jones TV, eds. The Merck manual of diagnosis and therapy. Rahway: Merck & Co., Inc., 2008:2992.
   Google Scholar
• Jemal A, Thun MJ, Ries LA, Howe HL, Weir HK, Center MM, et al. Annual report to the nation on the status of cancer, 1975-2005, featuring trends in lung cancer, tobacco use, and tobacco control. J Natl Cancer Inst 2008; 100:1672 - 94; http://dx.doi.org/10.1093/jnci/djn389; PMID: 19033571
   PubMed Web of Science ®Google Scholar
• Brenner C, Grimm S. The permeability transition pore complex in cancer cell death. Oncogene 2006; 25:4744 - 56; http://dx.doi.org/10.1038/sj.onc.1209609; PMID: 16892087
   PubMed Web of Science ®Google Scholar
• Rippo MR, Malisan F, Ravagnan L, Tomassini B, Condo I, Costantini P, et al. GD3 ganglioside directly targets mitochondria in a bcl-2-controlled fashion. FASEB J 2000; 14:2047 - 54; http://dx.doi.org/10.1096/fj.99-1028com; PMID: 11023989
   PubMed Web of Science ®Google Scholar
• Jimi S, Uchiyama M, Takaki A, Suzumiya J, Hara S. Mechanisms of cell death induced by cadmium and arsenic. Ann NY Acad Sci 2004; 1011:325 - 31; http://dx.doi.org/10.1196/annals.1293.032; PMID: 15126309
   PubMed Web of Science ®Google Scholar
• Novgorodov SA, Gudz TI, Milgrom YM, Brierley GP. The permeability transition in heart mitochondria is regulated synergistically by ADP and cyclosporin A. J Biol Chem 1992; 267:16274 - 82; PMID: 1644813
   PubMed Web of Science ®Google Scholar
• Lê Quôc K, Lê Quôc D. Involvement of the ADP/ATP carrier in calcium-induced perturbations of the mitochondrial inner membrane permeability: importance of the orientation of the nucleotide binding site. Arch Biochem Biophys 1988; 265:249 - 57; http://dx.doi.org/10.1016/0003-9861(88)90125-7; PMID: 2844116
   PubMed Web of Science ®Google Scholar
• Galluzzi L, Morselli E, Vitale I, Kepp O, Senovilla L, Criollo A, et al. miR-181a and miR-630 regulate cisplatin-induced cancer cell death. Cancer Res 2010; 70:1793 - 803; http://dx.doi.org/10.1158/0008-5472.CAN-09-3112; PMID: 20145152
   PubMed Web of Science ®Google Scholar
• Kepp O, Galluzzi L, Lipinski M, Yuan J, Kroemer G. Cell death assays for drug discovery. Nat Rev Drug Discov 2011; 10:221 - 37; http://dx.doi.org/10.1038/nrd3373; PMID: 21358741
   PubMed Web of Science ®Google Scholar
• Stoica BA, Movsesyan VA, Lea PM 4th, Faden AI. Ceramide-induced neuronal apoptosis is associated with dephosphorylation of Akt, BAD, FKHR, GSK-3beta, and induction of the mitochondrial-dependent intrinsic caspase pathway. Mol Cell Neurosci 2003; 22:365 - 82; http://dx.doi.org/10.1016/S1044-7431(02)00028-3; PMID: 12691738
   PubMed Web of Science ®Google Scholar
• Galluzzi L, Aaronson SA, Abrams J, Alnemri ES, Andrews DW, Baehrecke EH, et al. Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death Differ 2009; 16:1093 - 107; http://dx.doi.org/10.1038/cdd.2009.44; PMID: 19373242
   PubMed Web of Science ®Google Scholar
• Galluzzi L, Zamzami N, de La Motte Rouge T, Lemaire C, Brenner C, Kroemer G. Methods for the assessment of mitochondrial membrane permeabilization in apoptosis. Apoptosis 2007; 12:803 - 13; http://dx.doi.org/10.1007/s10495-007-0720-1; PMID: 17294081
   PubMed Web of Science ®Google Scholar
• Galluzzi L, Vitale I, Senovilla L, Olaussen KA, Pinna G, Eisenberg T, et al. Prognostic Impact of Vitamin B6 Metabolism in Lung Cancer. Cell Rep 2012; In press http://dx.doi.org/10.1016/j.celrep.2012.06.017; PMID: 22854025
   PubMed Web of Science ®Google Scholar
• Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, Cherry JM, et al, The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat Genet 2000; 25:25 - 9; http://dx.doi.org/10.1038/75556; PMID: 10802651
   PubMed Web of Science ®Google Scholar
• Kanehisa M. A database for post-genome analysis. Trends Genet 1997; 13:375 - 6; http://dx.doi.org/10.1016/S0168-9525(97)01223-7; PMID: 9287494
   PubMed Web of Science ®Google Scholar
• Alexa A, Rahnenführer J, Lengauer T. Improved scoring of functional groups from gene expression data by decorrelating GO graph structure. Bioinformatics 2006; 22:1600 - 7; http://dx.doi.org/10.1093/bioinformatics/btl140; PMID: 16606683
   PubMed Web of Science ®Google Scholar
• Pauleau AL, Galluzzi L, Scholz SR, Larochette N, Kepp O, Kroemer G. Unexpected role of the phosphate carrier in mitochondrial fragmentation. Cell Death Differ 2008; 15:616 - 8; http://dx.doi.org/10.1038/sj.cdd.4402295; PMID: 18174900
   PubMed Web of Science ®Google Scholar
• Poncet D, Pauleau AL, Szabadkai G, Vozza A, Scholz SR, Le Bras M, et al. Cytopathic effects of the cytomegalovirus-encoded apoptosis inhibitory protein vMIA. J Cell Biol 2006; 174:985 - 96; http://dx.doi.org/10.1083/jcb.200604069; PMID: 16982800
   PubMed Web of Science ®Google Scholar
• Büttner S, Ruli D, Vögtle FN, Galluzzi L, Moitzi B, Eisenberg T, et al. A yeast BH3-only protein mediates the mitochondrial pathway of apoptosis. EMBO J 2011; 30:2779 - 92; http://dx.doi.org/10.1038/emboj.2011.197; PMID: 21673659
   PubMed Web of Science ®Google Scholar
• Morigasaki S, Shimada K, Ikner A, Yanagida M, Shiozaki K. Glycolytic enzyme GAPDH promotes peroxide stress signaling through multistep phosphorelay to a MAPK cascade. Mol Cell 2008; 30:108 - 13; http://dx.doi.org/10.1016/j.molcel.2008.01.017; PMID: 18406331
   PubMed Web of Science ®Google Scholar
• Tarze A, Deniaud A, Le Bras M, Maillier E, Molle D, Larochette N, et al. GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilization. Oncogene 2007; 26:2606 - 20; http://dx.doi.org/10.1038/sj.onc.1210074; PMID: 17072346
   PubMed Web of Science ®Google Scholar
• Zhivotovsky B, Galluzzi L, Kepp O, Kroemer G. Adenine nucleotide translocase: a component of the phylogenetically conserved cell death machinery. Cell Death Differ 2009; 16:1419 - 25; http://dx.doi.org/10.1038/cdd.2009.118; PMID: 19696789
   PubMed Web of Science ®Google Scholar
• Futai E, Maeda T, Sorimachi H, Kitamoto K, Ishiura S, Suzuki K. The protease activity of a calpain-like cysteine protease in Saccharomyces cerevisiae is required for alkaline adaptation and sporulation. Mol Gen Genet 1999; 260:559 - 68; http://dx.doi.org/10.1007/s004380050929; PMID: 9928935
   PubMedGoogle Scholar
• Kroemer G, Jäättelä M. Lysosomes and autophagy in cell death control. Nat Rev Cancer 2005; 5:886 - 97; http://dx.doi.org/10.1038/nrc1738; PMID: 16239905
   PubMed Web of Science ®Google Scholar
• Vandenabeele P, Galluzzi L, Vanden Berghe T, Kroemer G. Molecular mechanisms of necroptosis: an ordered cellular explosion. Nat Rev Mol Cell Biol 2010; 11:700 - 14; http://dx.doi.org/10.1038/nrm2970; PMID: 20823910
   PubMed Web of Science ®Google Scholar
• Cheng EH, Sheiko TV, Fisher JK, Craigen WJ, Korsmeyer SJ. VDAC2 inhibits BAK activation and mitochondrial apoptosis. Science 2003; 301:513 - 7; http://dx.doi.org/10.1126/science.1083995; PMID: 12881569
   PubMed Web of Science ®Google Scholar
• de La Motte Rouge T, Galluzzi L, Olaussen KA, Zermati Y, Tasdemir E, Robert T, et al. A novel epidermal growth factor receptor inhibitor promotes apoptosis in non-small cell lung cancer cells resistant to erlotinib. Cancer Res 2007; 67:6253 - 62; http://dx.doi.org/10.1158/0008-5472.CAN-07-0538; PMID: 17616683
   PubMed Web of Science ®Google Scholar
• Boehrer S, Adès L, Braun T, Galluzzi L, Grosjean J, Fabre C, et al. Erlotinib exhibits antineoplastic off-target effects in AML and MDS: a preclinical study. Blood 2008; 111:2170 - 80; http://dx.doi.org/10.1182/blood-2007-07-100362; PMID: 17925489
   PubMed Web of Science ®Google Scholar
• Madeo F, Herker E, Maldener C, Wissing S, Lächelt S, Herlan M, et al. A caspase-related protease regulates apoptosis in yeast. Mol Cell 2002; 9:911 - 7; http://dx.doi.org/10.1016/S1097-2765(02)00501-4; PMID: 11983181
   PubMed Web of Science ®Google Scholar
• Zischka H, Larochette N, Hoffmann F, Hamöller D, Jägemann N, Lichtmannegger J, et al. Electrophoretic analysis of the mitochondrial outer membrane rupture induced by permeability transition. Anal Chem 2008; 80:5051 - 8; http://dx.doi.org/10.1021/ac800173r; PMID: 18510346
   PubMed Web of Science ®Google Scholar
• Morselli E, Maiuri MC, Markaki M, Megalou E, Pasparaki A, Palikaras K, et al. Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy. Cell Death Dis 2010; 1:e10; http://dx.doi.org/10.1038/cddis.2009.8; PMID: 21364612
   PubMed Web of Science ®Google Scholar
• Vitale I, Senovilla L, Jemaà M, Michaud M, Galluzzi L, Kepp O, et al. Multipolar mitosis of tetraploid cells: inhibition by p53 and dependency on Mos. EMBO J 2010; 29:1272 - 84; http://dx.doi.org/10.1038/emboj.2010.11; PMID: 20186124
   PubMed Web of Science ®Google Scholar