Impaired adult myeloid progenitor CMP and GMP cell function in conditional c-myb-knockout mice

References

• Akashi K, Traver D, Miyamoto T, Weissman IL. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature 2000; 404:193 - 7; http://dx.doi.org/10.1038/35004599; PMID: 10724173
   PubMed Web of Science ®Google Scholar
• Rosenbauer F, Tenen DG. Transcription factors in myeloid development: balancing differentiation with transformation. Nat Rev Immunol 2007; 7:105 - 17; http://dx.doi.org/10.1038/nri2024; PMID: 17259967
   PubMed Web of Science ®Google Scholar
• Greig KT, Carotta S, Nutt SL. Critical roles for c-Myb in hematopoietic progenitor cells. Semin Immunol 2008; 20:247 - 56; http://dx.doi.org/10.1016/j.smim.2008.05.003; PMID: 18585056
   PubMed Web of Science ®Google Scholar
• Oh IH, Reddy EP. The myb gene family in cell growth, differentiation and apoptosis. Oncogene 1999; 18:3017 - 33; http://dx.doi.org/10.1038/sj.onc.1202839; PMID: 10378697
   PubMed Web of Science ®Google Scholar
• Sarrazin S, Sieweke MH. c-Myb as a key player in the control of myeloid cell differentiation. In Frampton J, editor Myb Transcription Factors: Their Role in Growth, Differentiation and Disease The Netherlands: Kluwer Academic Publishers 2004:133-44.
   Google Scholar
• Bjerregaard MD, Jurlander J, Klausen P, Borregaard N, Cowland JB. The in vivo profile of transcription factors during neutrophil differentiation in human bone marrow. Blood 2003; 101:4322 - 32; http://dx.doi.org/10.1182/blood-2002-03-0835; PMID: 12560239
   PubMed Web of Science ®Google Scholar
• Gewirtz AM, Calabretta B. A c-myb antisense oligodeoxynucleotide inhibits normal human hematopoiesis in vitro. Science 1988; 242:1303 - 6; http://dx.doi.org/10.1126/science.2461588; PMID: 2461588
   PubMed Web of Science ®Google Scholar
• Burgess TL, Fisher EF, Ross SL, Bready JV, Qian YX, Bayewitch LA, et al. The antiproliferative activity of c-myb and c-myc antisense oligonucleotides in smooth muscle cells is caused by a nonantisense mechanism. Proc Natl Acad Sci USA 1995; 92:4051 - 5; http://dx.doi.org/10.1073/pnas.92.9.4051; PMID: 7732029
   PubMed Web of Science ®Google Scholar
• Lee SL, Wang Y, Milbrandt J. Unimpaired macrophage differentiation and activation in mice lacking the zinc finger transplantation factor NGFI-A (EGR1). Mol Cell Biol 1996; 16:4566 - 72; PMID: 8754857
   PubMed Web of Science ®Google Scholar
• Mucenski ML, McLain K, Kier AB, Swerdlow SH, Schreiner CM, Miller TA, et al. A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis. Cell 1991; 65:677 - 89; http://dx.doi.org/10.1016/0092-8674(91)90099-K; PMID: 1709592
   PubMed Web of Science ®Google Scholar
• Carpinelli MR, Hilton DJ, Metcalf D, Antonchuk JL, Hyland CD, Mifsud SL, et al. Suppressor screen in Mpl-/- mice: c-Myb mutation causes supraphysiological production of platelets in the absence of thrombopoietin signaling. Proc Natl Acad Sci USA 2004; 101:6553 - 8; http://dx.doi.org/10.1073/pnas.0401496101; PMID: 15071178
   PubMed Web of Science ®Google Scholar
• Sandberg ML, Sutton SE, Pletcher MT, Wiltshire T, Tarantino LM, Hogenesch JB, et al. c-Myb and p300 regulate hematopoietic stem cell proliferation and differentiation. Dev Cell 2005; 8:153 - 66; http://dx.doi.org/10.1016/j.devcel.2004.12.015; PMID: 15691758
   PubMed Web of Science ®Google Scholar
• García P, Clarke M, Vegiopoulos A, Berlanga O, Camelo A, Lorvellec M, et al. Reduced c-Myb activity compromises HSCs and leads to a myeloproliferation with a novel stem cell basis. EMBO J 2009; 28:1492 - 504; http://dx.doi.org/10.1038/emboj.2009.97; PMID: 19360001
   PubMed Web of Science ®Google Scholar
• Slamon DJ, Boone TC, Murdock DC, Keith DE, Press MF, Larson RA, et al. Studies of the human c-myb gene and its product in human acute leukemias. Science 1986; 233:347 - 51; http://dx.doi.org/10.1126/science.3014652; PMID: 3014652
   PubMed Web of Science ®Google Scholar
• Clappier E, Cuccuini W, Kalota A, Crinquette A, Cayuela JM, Dik WA, et al. The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL), the translocation defining a new T-ALL subtype in very young children. Blood 2007; 110:1251 - 61; http://dx.doi.org/10.1182/blood-2006-12-064683; PMID: 17452517
   PubMed Web of Science ®Google Scholar
• Lahortiga I, De Keersmaecker K, Van Vlierberghe P, Graux C, Cauwelier B, Lambert F, et al. Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia. Nat Genet 2007; 39:593 - 5; http://dx.doi.org/10.1038/ng2025; PMID: 17435759
   PubMed Web of Science ®Google Scholar
• O’Neil J, Tchinda J, Gutierrez A, Moreau L, Maser RS, Wong KK, et al. Alu elements mediate MYB gene tandem duplication in human T-ALL. J Exp Med 2007; 204:3059 - 66; http://dx.doi.org/10.1084/jem.20071637; PMID: 18070937
   PubMed Web of Science ®Google Scholar
• Murati A, Gervais C, Carbuccia N, Finetti P, Cervera N, Adélaïde J, et al. Groupe Francophone de Cytogénétique Hématologique. Genome profiling of acute myelomonocytic leukemia: alteration of the MYB locus in MYST3-linked cases. Leukemia 2009; 23:85 - 94; http://dx.doi.org/10.1038/leu.2008.257; PMID: 18818702
   PubMed Web of Science ®Google Scholar
• Lieu YK, Reddy EP. Conditional c-myb knockout in adult hematopoietic stem cells leads to loss of self-renewal due to impaired proliferation and accelerated differentiation. Proc Natl Acad Sci USA 2009; 106:21689 - 94; http://dx.doi.org/10.1073/pnas.0907623106; PMID: 19955420
   PubMed Web of Science ®Google Scholar
• Lübbert M, Herrmann F, Koeffler HP. Expression and regulation of myeloid-specific genes in normal and leukemic myeloid cells. Blood 1991; 77:909 - 24; PMID: 1847312
   PubMed Web of Science ®Google Scholar
• Hestdal K, Ruscetti FW, Ihle JN, Jacobsen SE, Dubois CM, Kopp WC, et al. Characterization and regulation of RB6-8C5 antigen expression on murine bone marrow cells. J Immunol 1991; 147:22 - 8; PMID: 1711076
   PubMed Web of Science ®Google Scholar
• Lagasse E, Weissman IL. Flow cytometric identification of murine neutrophils and monocytes. J Immunol Methods 1996; 197:139 - 50; http://dx.doi.org/10.1016/0022-1759(96)00138-X; PMID: 8890901
   PubMed Web of Science ®Google Scholar
• Liu Q, VanHoy RW, Zhou JH, Dantzer R, Freund GG, Kelley KW. Elevated cyclin E levels, inactive retinoblastoma protein, and suppression of the p27(KIP1) inhibitor characterize early development of promyeloid cells into macrophages. Mol Cell Biol 1999; 19:6229 - 39; PMID: 10454569
   PubMed Web of Science ®Google Scholar
• Britos-Bray M, Friedman AD. Core binding factor cannot synergistically activate the myeloperoxidase proximal enhancer in immature myeloid cells without c-Myb. Mol Cell Biol 1997; 17:5127 - 35; PMID: 9271390
   PubMed Web of Science ®Google Scholar
• Oelgeschläger M, Nuchprayoon I, Lüscher B, Friedman AD. C/EBP, c-Myb, and PU.1 cooperate to regulate the neutrophil elastase promoter. Mol Cell Biol 1996; 16:4717 - 25; PMID: 8756629
   PubMed Web of Science ®Google Scholar
• Lutz PG, Houzel-Charavel A, Moog-Lutz C, Cayre YE. Myeloblastin is an Myb target gene: mechanisms of regulation in myeloid leukemia cells growth-arrested by retinoic acid. Blood 2001; 97:2449 - 56; http://dx.doi.org/10.1182/blood.V97.8.2449; PMID: 11290610
   PubMed Web of Science ®Google Scholar
• Rushton JJ, Davis LM, Lei W, Mo X, Leutz A, Ness SA. Distinct changes in gene expression induced by A-Myb, B-Myb and c-Myb proteins. Oncogene 2003; 22:308 - 13; http://dx.doi.org/10.1038/sj.onc.1206131; PMID: 12527900
   PubMed Web of Science ®Google Scholar
• Wolff L, Schmidt M, Koller R, Haviernik P, Watson R, Bies J, et al. Three genes with different functions in transformation are regulated by c-Myb in myeloid cells. Blood Cells Mol Dis 2001; 27:483 - 8; http://dx.doi.org/10.1006/bcmd.2001.0409; PMID: 11259171
   PubMed Web of Science ®Google Scholar
• Emambokus N, Vegiopoulos A, Harman B, Jenkinson E, Anderson G, Frampton J. Progression through key stages of haemopoiesis is dependent on distinct threshold levels of c-Myb. EMBO J 2003; 22:4478 - 88; http://dx.doi.org/10.1093/emboj/cdg434; PMID: 12941699
   PubMed Web of Science ®Google Scholar
• Ferrari S, Donelli A, Manfredini R, Sarti M, Roncaglia R, Tagliafico E, et al. Differential effects of c-myb and c-fes antisense oligodeoxynucleotides on granulocytic differentiation of human myeloid leukemia HL60 cells. Cell Growth Differ 1990; 1:543 - 8; PMID: 2088479
   PubMedGoogle Scholar
• Ness SA, Marknell A, Graf T. The v-myb oncogene product binds to and activates the promyelocyte-specific mim-1 gene. Cell 1989; 59:1115 - 25; http://dx.doi.org/10.1016/0092-8674(89)90767-8; PMID: 2688896
   PubMed Web of Science ®Google Scholar
• Beug H, Leutz A, Kahn P, Graf T. Ts mutants of E26 leukemia virus allow transformed myeloblasts, but not erythroblasts or fibroblasts, to differentiate at the nonpermissive temperature. Cell 1984; 39:579 - 88; http://dx.doi.org/10.1016/0092-8674(84)90465-3; PMID: 6096011
   PubMed Web of Science ®Google Scholar
• Beug H, Blundell PA, Graf T. Reversibility of differentiation and proliferative capacity in avian myelomonocytic cells transformed by tsE26 leukemia virus. Genes Dev 1987; 1:277 - 86; http://dx.doi.org/10.1101/gad.1.3.277; PMID: 2824281
   PubMed Web of Science ®Google Scholar
• Burk O, Klempnauer KH. Estrogen-dependent alterations in differentiation state of myeloid cells caused by a v-myb/estrogen receptor fusion protein. EMBO J 1991; 10:3713 - 9; PMID: 1718743
   PubMed Web of Science ®Google Scholar
• Hock H, Hamblen MJ, Rooke HM, Traver D, Bronson RT, Cameron S, et al. Intrinsic requirement for zinc finger transcription factor Gfi-1 in neutrophil differentiation. Immunity 2003; 18:109 - 20; http://dx.doi.org/10.1016/S1074-7613(02)00501-0; PMID: 12530980
   PubMed Web of Science ®Google Scholar
• Zhang DE, Zhang P, Wang ND, Hetherington CJ, Darlington GJ, Tenen DG. Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice. Proc Natl Acad Sci USA 1997; 94:569 - 74; http://dx.doi.org/10.1073/pnas.94.2.569; PMID: 9012825
   PubMed Web of Science ®Google Scholar
• Hoffman B, Amanullah A, Shafarenko M, Liebermann DA. The proto-oncogene c-myc in hematopoietic development and leukemogenesis. Oncogene 2002; 21:3414 - 21; http://dx.doi.org/10.1038/sj.onc.1205400; PMID: 12032779
   PubMed Web of Science ®Google Scholar
• Ma Q, Jones D, Borghesani PR, Segal RA, Nagasawa T, Kishimoto T, et al. Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice. Proc Natl Acad Sci USA 1998; 95:9448 - 53; http://dx.doi.org/10.1073/pnas.95.16.9448; PMID: 9689100
   PubMed Web of Science ®Google Scholar
• Frampton J, Ramqvist T, Graf T. v-Myb of E26 leukemia virus up-regulates bcl-2 and suppresses apoptosis in myeloid cells. Genes Dev 1996; 10:2720 - 31; http://dx.doi.org/10.1101/gad.10.21.2720; PMID: 8946913
   PubMed Web of Science ®Google Scholar