dj-1β regulates oxidative stress, insulin-like signaling and development in Drosophila melanogaster

References

• Wilson MA. The role of cysteine oxidation in DJ-1 function and dysfunction. Antioxid Redox Signal 2011; 15:111 - 22; http://dx.doi.org/10.1089/ars.2010.3481; PMID: 20812780
   PubMed Web of Science ®Google Scholar
• Zhang L, Shimoji M, Thomas B, Moore DJ, Yu SW, Marupudi NI, et al. Mitochondrial localization of the Parkinson’s disease related protein DJ-1: implications for pathogenesis. Hum Mol Genet 2005; 14:2063 - 73; http://dx.doi.org/10.1093/hmg/ddi211; PMID: 15944198
   PubMed Web of Science ®Google Scholar
• Lev N, Ickowicz D, Melamed E, Offen D. Oxidative insults induce DJ-1 upregulation and redistribution: implications for neuroprotection. Neurotoxicology 2008; 29:397 - 405; http://dx.doi.org/10.1016/j.neuro.2008.01.007; PMID: 18377993
   PubMed Web of Science ®Google Scholar
• Bezard E, Przedborski S. A tale on animal models of Parkinson’s disease. Mov Disord 2011; 26:993 - 1002; http://dx.doi.org/10.1002/mds.23696; PMID: 21626544
   PubMed Web of Science ®Google Scholar
• Hayashi T, Ishimori C, Takahashi-Niki K, Taira T, Kim YC, Maita H, et al. DJ-1 binds to mitochondrial complex I and maintains its activity. Biochem Biophys Res Commun 2009; 390:667 - 72; http://dx.doi.org/10.1016/j.bbrc.2009.10.025; PMID: 19822128
   PubMed Web of Science ®Google Scholar
• Meulener M, Whitworth AJ, Armstrong-Gold CE, Rizzu P, Heutink P, Wes PD, et al. Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson’s disease. Curr Biol 2005; 15:1572 - 7; http://dx.doi.org/10.1016/j.cub.2005.07.064; PMID: 16139213
   PubMed Web of Science ®Google Scholar
• Park J, Kim SY, Cha GH, Lee SB, Kim S, Chung J. Drosophila DJ-1 mutants show oxidative stress-sensitive locomotive dysfunction. Gene 2005; 361:133 - 9; http://dx.doi.org/10.1016/j.gene.2005.06.040; PMID: 16203113
   PubMed Web of Science ®Google Scholar
• Andres-Mateos E, Perier C, Zhang L, Blanchard-Fillion B, Greco TM, Thomas B, et al. DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase. Proc Natl Acad Sci USA 2007; 104:14807 - 12; http://dx.doi.org/10.1073/pnas.0703219104; PMID: 17766438
   PubMed Web of Science ®Google Scholar
• Fernandez-Ayala DJ, Sanz A, Vartiainen S, Kemppainen KK, Babusiak M, Mustalahti E, et al. Expression of the Ciona intestinalis alternative oxidase (AOX) in Drosophila complements defects in mitochondrial oxidative phosphorylation. Cell Metab 2009; 9:449 - 60; http://dx.doi.org/10.1016/j.cmet.2009.03.004; PMID: 19416715
   PubMed Web of Science ®Google Scholar
• Dufour E, Boulay J, Rincheval V, Sainsard-Chanet A. A causal link between respiration and senescence in Podospora anserina. Proc Natl Acad Sci USA 2000; 97:4138 - 43; http://dx.doi.org/10.1073/pnas.070501997; PMID: 10759557
   PubMed Web of Science ®Google Scholar
• Sanz A, Fernández-Ayala DJ, Stefanatos RK, Jacobs HT. Mitochondrial ROS production correlates with, but does not directly regulate lifespan in Drosophila. Aging (Albany NY) 2010; 2:200 - 23; PMID: 20453260
   PubMedGoogle Scholar
• Yang W, Hekimi S. A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans. PLoS Biol 2010; 8:e1000556; http://dx.doi.org/10.1371/journal.pbio.1000556; PMID: 21151885
   PubMed Web of Science ®Google Scholar
• Sanz A, Caro P, Ayala V, Portero-Otin M, Pamplona R, Barja G. Methionine restriction decreases mitochondrial oxygen radical generation and leak as well as oxidative damage to mitochondrial DNA and proteins. FASEB J 2006; 20:1064 - 73; http://dx.doi.org/10.1096/fj.05-5568com; PMID: 16770005
   PubMed Web of Science ®Google Scholar
• Martínez A, Portero-Otin M, Pamplona R, Ferrer I. Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates. Brain Pathol 2010; 20:281 - 97; http://dx.doi.org/10.1111/j.1750-3639.2009.00326.x; PMID: 19725834
   PubMed Web of Science ®Google Scholar
• Jacobson J, Lambert AJ, Portero-Otín M, Pamplona R, Magwere T, Miwa S, et al. Biomarkers of aging in Drosophila. Aging Cell 2010; 9:466 - 77; http://dx.doi.org/10.1111/j.1474-9726.2010.00573.x; PMID: 20367621
   PubMed Web of Science ®Google Scholar
• Zarse K, Schmeisser S, Groth M, Priebe S, Beuster G, Kuhlow D, et al. Impaired insulin/IGF1 signaling extends life span by promoting mitochondrial L-proline catabolism to induce a transient ROS signal. Cell Metab 2012; 15:451 - 65; http://dx.doi.org/10.1016/j.cmet.2012.02.013; PMID: 22482728
   PubMed Web of Science ®Google Scholar
• Cabreiro F, Ackerman D, Doonan R, Araiz C, Back P, Papp D, et al. Increased life span from overexpression of superoxide dismutase in Caenorhabditis elegans is not caused by decreased oxidative damage. Free Radic Biol Med 2011; 51:1575 - 82; http://dx.doi.org/10.1016/j.freeradbiomed.2011.07.020; PMID: 21839827
   PubMed Web of Science ®Google Scholar
• Karpac J, Hull-Thompson J, Falleur M, Jasper H. JNK signaling in insulin-producing cells is required for adaptive responses to stress in Drosophila. Aging Cell 2009; 8:288 - 95; http://dx.doi.org/10.1111/j.1474-9726.2009.00476.x; PMID: 19627268
   PubMed Web of Science ®Google Scholar
• Wang PY, Neretti N, Whitaker R, Hosier S, Chang C, Lu D, et al. Long-lived Indy and calorie restriction interact to extend life span. Proc Natl Acad Sci USA 2009; 106:9262 - 7; http://dx.doi.org/10.1073/pnas.0904115106; PMID: 19470468
   PubMed Web of Science ®Google Scholar
• Stefanatos R, Sanz A. Mitochondrial complex I: a central regulator of the aging process. Cell Cycle 2011; 10:1528 - 32; http://dx.doi.org/10.4161/cc.10.10.15496; PMID: 21471732
   PubMed Web of Science ®Google Scholar
• Zid BM, Rogers AN, Katewa SD, Vargas MA, Kolipinski MC, Lu TA, et al. 4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila. Cell 2009; 139:149 - 60; http://dx.doi.org/10.1016/j.cell.2009.07.034; PMID: 19804760
   PubMed Web of Science ®Google Scholar
• Rera M, Bahadorani S, Cho J, Koehler CL, Ulgherait M, Hur JH, et al. Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog. Cell Metab 2011; 14:623 - 34; http://dx.doi.org/10.1016/j.cmet.2011.09.013; PMID: 22055505
   PubMed Web of Science ®Google Scholar
• Tissenbaum HA, Guarente L. Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 2001; 410:227 - 30; http://dx.doi.org/10.1038/35065638; PMID: 11242085
   PubMed Web of Science ®Google Scholar
• Burnett C, Valentini S, Cabreiro F, Goss M, Somogyvári M, Piper MD, et al. Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila. Nature 2011; 477:482 - 5; http://dx.doi.org/10.1038/nature10296; PMID: 21938067
   PubMed Web of Science ®Google Scholar
• Rogina B, Helfand SL. Sir2 mediates longevity in the fly through a pathway related to calorie restriction. Proc Natl Acad Sci USA 2004; 101:15998 - 6003; http://dx.doi.org/10.1073/pnas.0404184101; PMID: 15520384
   PubMed Web of Science ®Google Scholar
• Oberdoerffer P, Michan S, McVay M, Mostoslavsky R, Vann J, Park SK, et al. SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging. Cell 2008; 135:907 - 18; http://dx.doi.org/10.1016/j.cell.2008.10.025; PMID: 19041753
   PubMed Web of Science ®Google Scholar
• Slaidina M, Delanoue R, Gronke S, Partridge L, Léopold P. A Drosophila insulin-like peptide promotes growth during nonfeeding states. Dev Cell 2009; 17:874 - 84; http://dx.doi.org/10.1016/j.devcel.2009.10.009; PMID: 20059956
   PubMed Web of Science ®Google Scholar
• van der Brug MP, Blackinton J, Chandran J, Hao LY, Lal A, Mazan-Mamczarz K, et al. RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways. Proc Natl Acad Sci USA 2008; 105:10244 - 9; http://dx.doi.org/10.1073/pnas.0708518105; PMID: 18626009
   PubMed Web of Science ®Google Scholar
• Missirlis F, Hu J, Kirby K, Hilliker AJ, Rouault TA, Phillips JP. Compartment-specific protection of iron-sulfur proteins by superoxide dismutase. J Biol Chem 2003; 278:47365 - 9; http://dx.doi.org/10.1074/jbc.M307700200; PMID: 12972424
   PubMed Web of Science ®Google Scholar
• Van Raamsdonk JM, Hekimi S. Superoxide dismutase is dispensable for normal animal lifespan. Proc Natl Acad Sci USA 2012; 109:5785 - 90; http://dx.doi.org/10.1073/pnas.1116158109; PMID: 22451939
   PubMed Web of Science ®Google Scholar
• Mukherjee S, Forde R, Belton A, Duttaroy A. SOD2, the principal scavenger of mitochondrial superoxide, is dispensable for embryogenesis and imaginal tissue development but essential for adult survival. Fly (Austin) 2011; 5:39 - 46; PMID: 21212740
   PubMed Web of Science ®Google Scholar
• Godenschwege T, Forde R, Davis CP, Paul A, Beckwith K, Duttaroy A. Mitochondrial superoxide radicals differentially affect muscle activity and neural function. Genetics 2009; 183:175 - 84; http://dx.doi.org/10.1534/genetics.109.103515; PMID: 19546321
   PubMed Web of Science ®Google Scholar
• Sohal RS. Effect of hydrogen peroxide administration on life span, superoxide dismutase, catalase, and glutathione in the adult housefly, Musca domestica. Exp Gerontol 1988; 23:211 - 6; http://dx.doi.org/10.1016/0531-5565(88)90008-3; PMID: 2849553
   PubMed Web of Science ®Google Scholar
• Martin I, Jones MA, Grotewiel M. Manipulation of Sod1 expression ubiquitously, but not in the nervous system or muscle, impacts age-related parameters in Drosophila. FEBS Lett 2009; 583:2308 - 14; http://dx.doi.org/10.1016/j.febslet.2009.06.023; PMID: 19540235
   PubMed Web of Science ®Google Scholar
• Curtis C, Landis GN, Folk D, Wehr NB, Hoe N, Waskar M, et al. Transcriptional profiling of MnSOD-mediated lifespan extension in Drosophila reveals a species-general network of aging and metabolic genes. Genome Biol 2007; 8:R262; http://dx.doi.org/10.1186/gb-2007-8-12-r262; PMID: 18067683
   PubMed Web of Science ®Google Scholar
• Ristow M, Zarse K. How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis). Exp Gerontol 2010; 45:410 - 8; http://dx.doi.org/10.1016/j.exger.2010.03.014; PMID: 20350594
   PubMed Web of Science ®Google Scholar
• Muller FL, Lustgarten MS, Jang Y, Richardson A, Van Remmen H. Trends in oxidative aging theories. Free Radic Biol Med 2007; 43:477 - 503; http://dx.doi.org/10.1016/j.freeradbiomed.2007.03.034; PMID: 17640558
   PubMed Web of Science ®Google Scholar
• Kirby K, Hu J, Hilliker AJ, Phillips JP. RNA interference-mediated silencing of Sod2 in Drosophila leads to early adult-onset mortality and elevated endogenous oxidative stress. Proc Natl Acad Sci USA 2002; 99:16162 - 7; http://dx.doi.org/10.1073/pnas.252342899; PMID: 12456885
   PubMed Web of Science ®Google Scholar
• Mockett RJ, Sohal BH, Sohal RS. Expression of multiple copies of mitochondrially targeted catalase or genomic Mn superoxide dismutase transgenes does not extend the life span of Drosophila melanogaster. Free Radic Biol Med 2010; 49:2028 - 31; http://dx.doi.org/10.1016/j.freeradbiomed.2010.09.029; PMID: 20923705
   PubMed Web of Science ®Google Scholar
• Hao LY, Giasson BI, Bonini NM. DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function. Proc Natl Acad Sci USA 2010; 107:9747 - 52; http://dx.doi.org/10.1073/pnas.0911175107; PMID: 20457924
   PubMed Web of Science ®Google Scholar
• Ristow M, Schmeisser S. Extending life span by increasing oxidative stress. Free Radic Biol Med 2011; 51:327 - 36; http://dx.doi.org/10.1016/j.freeradbiomed.2011.05.010; PMID: 21619928
   PubMed Web of Science ®Google Scholar
• Owusu-Ansah E, Yavari A, Mandal S, Banerjee U. Distinct mitochondrial retrograde signals control the G1-S cell cycle checkpoint. Nat Genet 2008; 40:356 - 61; http://dx.doi.org/10.1038/ng.2007.50; PMID: 18246068
   PubMed Web of Science ®Google Scholar
• Grönke S, Clarke DF, Broughton S, Andrews TD, Partridge L. Molecular evolution and functional characterization of Drosophila insulin-like peptides. PLoS Genet 2010; 6:e1000857; http://dx.doi.org/10.1371/journal.pgen.1000857; PMID: 20195512
   PubMed Web of Science ®Google Scholar
• Yang Y, Gehrke S, Haque ME, Imai Y, Kosek J, Yang L, et al. Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling. Proc Natl Acad Sci USA 2005; 102:13670 - 5; http://dx.doi.org/10.1073/pnas.0504610102; PMID: 16155123
   PubMed Web of Science ®Google Scholar
• Wang MC, Bohmann D, Jasper H. JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling. Cell 2005; 121:115 - 25; http://dx.doi.org/10.1016/j.cell.2005.02.030; PMID: 15820683
   PubMed Web of Science ®Google Scholar
• Karpac J, Younger A, Jasper H. Dynamic coordination of innate immune signaling and insulin signaling regulates systemic responses to localized DNA damage. Dev Cell 2011; 20:841 - 54; http://dx.doi.org/10.1016/j.devcel.2011.05.011; PMID: 21664581
   PubMed Web of Science ®Google Scholar
• Nisoli E, Tonello C, Cardile A, Cozzi V, Bracale R, Tedesco L, et al. Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS. Science 2005; 310:314 - 7; http://dx.doi.org/10.1126/science.1117728; PMID: 16224023
   PubMed Web of Science ®Google Scholar
• Strobel NA, Peake JM, Matsumoto A, Marsh SA, Coombes JS, Wadley GD. Antioxidant supplementation reduces skeletal muscle mitochondrial biogenesis. Med Sci Sports Exerc 2011; 43:1017 - 24; http://dx.doi.org/10.1249/MSS.0b013e318203afa3; PMID: 21085043
   PubMed Web of Science ®Google Scholar
• Hardie DG. Sensing of energy and nutrients by AMP-activated protein kinase. Am J Clin Nutr 2011; 93:891S - 6; http://dx.doi.org/10.3945/ajcn.110.001925; PMID: 21325438
   PubMed Web of Science ®Google Scholar
• Yang W, Hekimi S. Two modes of mitochondrial dysfunction lead independently to lifespan extension in Caenorhabditis elegans. Aging Cell 2010; 9:433 - 47; http://dx.doi.org/10.1111/j.1474-9726.2010.00571.x; PMID: 20346072
   PubMed Web of Science ®Google Scholar
• Hur JH, Cho J, Walker DW. Aging: Dial M for Mitochondria. Aging (Albany NY) 2010; 2:69 - 73; PMID: 20228940
   PubMedGoogle Scholar
• Dell’agnello C, Leo S, Agostino A, Szabadkai G, Tiveron C, Zulian A, et al. Increased longevity and refractoriness to Ca(2+)-dependent neurodegeneration in Surf1 knockout mice. Hum Mol Genet 2007; 16:431 - 44; http://dx.doi.org/10.1093/hmg/ddl477; PMID: 17210671
   PubMed Web of Science ®Google Scholar
• Kuang J, Ebert PR. The failure to extend lifespan via disruption of complex II is linked to preservation of dynamic control of energy metabolism. Mitochondrion 2011; PMID: 22122855
   PubMed Web of Science ®Google Scholar
• Copeland JM, Cho J, Lo T Jr., Hur JH, Bahadorani S, Arabyan T, et al. Extension of Drosophila life span by RNAi of the mitochondrial respiratory chain. Curr Biol 2009; 19:1591 - 8; http://dx.doi.org/10.1016/j.cub.2009.08.016; PMID: 19747824
   PubMed Web of Science ®Google Scholar
• Bosch-Presegué L, Raurell-Vila H, Marazuela-Duque A, Kane-Goldsmith N, Valle A, Oliver J, et al. Stabilization of Suv39H1 by SirT1 is part of oxidative stress response and ensures genome protection. Mol Cell 2011; 42:210 - 23; http://dx.doi.org/10.1016/j.molcel.2011.02.034; PMID: 21504832
   PubMed Web of Science ®Google Scholar
• Banerjee KK, Ayyub C, Sengupta S, Kolthur-Seetharam U. dSir2 deficiency in the fatbody, but not muscles, affects systemic insulin signaling, fat mobilization and starvation survival in flies. Aging (Albany NY) 2012; 4:206 - 23; PMID: 22411915
   PubMedGoogle Scholar
• Sorensen M, Sanz A, Gómez J, Pamplona R, Portero-Otín M, Gredilla R, et al. Effects of fasting on oxidative stress in rat liver mitochondria. Free Radic Res 2006; 40:339 - 47; http://dx.doi.org/10.1080/10715760500250182; PMID: 16517498
   PubMed Web of Science ®Google Scholar
• Bauer J, Antosh M, Chang C, Schorl C, Kolli S, Neretti N, et al. Comparative transcriptional profiling identifies takeout as a gene that regulates life span. Aging (Albany NY) 2010; 2:298 - 310; PMID: 20519778
   PubMedGoogle Scholar
• Jang YC, Lustgarten MS, Liu Y, Muller FL, Bhattacharya A, Liang H, et al. Increased superoxide in vivo accelerates age-associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration. FASEB J 2010; 24:1376 - 90; http://dx.doi.org/10.1096/fj.09-146308; PMID: 20040516
   PubMed Web of Science ®Google Scholar
• Haselton AT, Fridell YW. Adult Drosophila melanogaster as a model for the study of glucose homeostasis. Aging (Albany NY) 2010; 2:523 - 6; PMID: 20689157
   PubMedGoogle Scholar
• Broughton S, Alic N, Slack C, Bass T, Ikeya T, Vinti G, et al. Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs. PLoS One 2008; 3:e3721; http://dx.doi.org/10.1371/journal.pone.0003721; PMID: 19005568
   PubMed Web of Science ®Google Scholar
• de Magalhães JP, Church GM. Cells discover fire: employing reactive oxygen species in development and consequences for aging. Exp Gerontol 2006; 41:1 - 10; http://dx.doi.org/10.1016/j.exger.2005.09.002; PMID: 16226003
   PubMed Web of Science ®Google Scholar
• Burdon RH. Superoxide and hydrogen peroxide in relation to mammalian cell proliferation. Free Radic Biol Med 1995; 18:775 - 94; http://dx.doi.org/10.1016/0891-5849(94)00198-S; PMID: 7750801
   PubMed Web of Science ®Google Scholar
• Lee S, Tak E, Lee J, Rashid MA, Murphy MP, Ha J, et al. Mitochondrial H2O2 generated from electron transport chain complex I stimulates muscle differentiation. Cell Res 2011; 21:817 - 34; http://dx.doi.org/10.1038/cr.2011.55; PMID: 21445095
   PubMed Web of Science ®Google Scholar
• Furukawa A, Tada-Oikawa S, Kawanishi S, Oikawa S. H2O2 accelerates cellular senescence by accumulation of acetylated p53 via decrease in the function of SIRT1 by NAD+ depletion. Cell Physiol Biochem 2007; 20:45 - 54; PMID: 17595514
   PubMed Web of Science ®Google Scholar
• Albrecht SC, Barata AG, Grosshans J, Teleman AA, Dick TP. In vivo mapping of hydrogen peroxide and oxidized glutathione reveals chemical and regional specificity of redox homeostasis. Cell Metab 2011; 14:819 - 29; http://dx.doi.org/10.1016/j.cmet.2011.10.010; PMID: 22100409
   PubMed Web of Science ®Google Scholar
• Mair W, Piper MD, Partridge L. Calories do not explain extension of life span by dietary restriction in Drosophila. PLoS Biol 2005; 3:e223; http://dx.doi.org/10.1371/journal.pbio.0030223; PMID: 16000018
   PubMed Web of Science ®Google Scholar
• Sanz A, Stefanatos R, McIlroy G. Production of reactive oxygen species by the mitochondrial electron transport chain in Drosophila melanogaster. J Bioenerg Biomembr 2010; 42:135 - 42; http://dx.doi.org/10.1007/s10863-010-9281-z; PMID: 20300811
   PubMed Web of Science ®Google Scholar
• Sanz A, Soikkeli M, Portero-Otín M, Wilson A, Kemppainen E, McIlroy G, et al. Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction. Proc Natl Acad Sci USA 2010; 107:9105 - 10; http://dx.doi.org/10.1073/pnas.0911539107; PMID: 20435911
   PubMed Web of Science ®Google Scholar