References
- Li M, Fang X, Baker DJ, Guo L, Gao X, Wei Z, et al. The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis. Proc Natl Acad Sci USA 2010; 107:14188 - 93; http://dx.doi.org/10.1073/pnas.1005960107; PMID: 20663956
- Dekanty A, Barrio L, Muzzopappa M, Auer H, Milán M. Aneuploidy-induced delaminating cells drive tumorigenesis in Drosophila epithelia. Proc Natl Acad Sci USA 2012; 109:20549 - 54; http://dx.doi.org/10.1073/pnas.1206675109; PMID: 23184991
- Castellanos E, Dominguez P, Gonzalez C. Centrosome dysfunction in Drosophila neural stem cells causes tumors that are not due to genome instability. Curr Biol 2008; 18:1209 - 14; http://dx.doi.org/10.1016/j.cub.2008.07.029; PMID: 18656356
- Cohen SM. Imaginal disc development. In: Martinez-Arias A, Bate M, eds. Drosophila Development. Cold Spring Harbor: Cold Spring Harbor Press, 1993:747-841
- Brodsky MH, Nordstrom W, Tsang G, Kwan E, Rubin GM, Abrams JM. Drosophila p53 binds a damage response element at the reaper locus. Cell 2000; 101:103 - 13; http://dx.doi.org/10.1016/S0092-8674(00)80627-3; PMID: 10778860
- Jin S, Martinek S, Joo WS, Wortman JR, Mirkovic N, Sali A, et al. Identification and characterization of a p53 homologue in Drosophila melanogaster. Proc Natl Acad Sci USA 2000; 97:7301 - 6; http://dx.doi.org/10.1073/pnas.97.13.7301; PMID: 10860994
- Ollmann M, Young LM, Di Como CJ, Karim F, Belvin M, Robertson S, et al. Drosophila p53 is a structural and functional homolog of the tumor suppressor p53. Cell 2000; 101:91 - 101; http://dx.doi.org/10.1016/S0092-8674(00)80626-1; PMID: 10778859
- Pagliarini RA, Xu T. A genetic screen in Drosophila for metastatic behavior. Science 2003; 302:1227 - 31; http://dx.doi.org/10.1126/science.1088474; PMID: 14551319
- Uhlirova M, Bohmann D. JNK- and Fos-regulated Mmp1 expression cooperates with Ras to induce invasive tumors in Drosophila. EMBO J 2006; 25:5294 - 304; http://dx.doi.org/10.1038/sj.emboj.7601401; PMID: 17082773
- Brumby AM, Richardson HE. scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila. EMBO J 2003; 22:5769 - 79; http://dx.doi.org/10.1093/emboj/cdg548; PMID: 14592975
- Lim J, Thiery JP. Epithelial-mesenchymal transitions: insights from development. Development 2012; 139:3471 - 86; http://dx.doi.org/10.1242/dev.071209; PMID: 22949611
- Srivastava A, Pastor-Pareja JC, Igaki T, Pagliarini R, Xu T. Basement membrane remodeling is essential for Drosophila disc eversion and tumor invasion. Proc Natl Acad Sci USA 2007; 104:2721 - 6; http://dx.doi.org/10.1073/pnas.0611666104; PMID: 17301221
- Ohsawa S, Sato Y, Enomoto M, Nakamura M, Betsumiya A, Igaki T. Mitochondrial defect drives non-autonomous tumour progression through Hippo signalling in Drosophila. Nature 2012; 490:547 - 51; http://dx.doi.org/10.1038/nature11452; PMID: 23023132
- Cordero JB, Macagno JP, Stefanatos RK, Strathdee KE, Cagan RL, Vidal M. Oncogenic Ras diverts a host TNF tumor suppressor activity into tumor promoter. Dev Cell 2010; 18:999 - 1011; http://dx.doi.org/10.1016/j.devcel.2010.05.014; PMID: 20627081
- Halazonetis TD, Gorgoulis VG, Bartek J. An oncogene-induced DNA damage model for cancer development. Science 2008; 319:1352 - 5; http://dx.doi.org/10.1126/science.1140735; PMID: 18323444
- Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011; 144:646 - 74; http://dx.doi.org/10.1016/j.cell.2011.02.013; PMID: 21376230
- Pfau SJ, Amon A. Chromosomal instability and aneuploidy in cancer: from yeast to man. EMBO Rep 2012; 13:515 - 27; http://dx.doi.org/10.1038/embor.2012.65; PMID: 22614003
- Solomon DA, Kim T, Diaz-Martinez LA, Fair J, Elkahloun AG, Harris BT, et al. Mutational inactivation of STAG2 causes aneuploidy in human cancer. Science 2011; 333:1039 - 43; http://dx.doi.org/10.1126/science.1203619; PMID: 21852505
- Sheltzer JM, Blank HM, Pfau SJ, Tange Y, George BM, Humpton TJ, et al. Aneuploidy drives genomic instability in yeast. Science 2011; 333:1026 - 30; http://dx.doi.org/10.1126/science.1206412; PMID: 21852501
- Chi YH, Ward JM, Cheng LI, Yasunaga J, Jeang KT. Spindle assembly checkpoint and p53 deficiencies cooperate for tumorigenesis in mice. Int J Cancer 2009; 124:1483 - 9; http://dx.doi.org/10.1002/ijc.24094; PMID: 19065665
- Oromendia AB, Dodgson SE, Amon A. Aneuploidy causes proteotoxic stress in yeast. Genes Dev 2012; 26:2696 - 708; http://dx.doi.org/10.1101/gad.207407.112; PMID: 23222101
- Torres EM, Dephoure N, Panneerselvam A, Tucker CM, Whittaker CA, Gygi SP, et al. Identification of aneuploidy-tolerating mutations. Cell 2010; 143:71 - 83; http://dx.doi.org/10.1016/j.cell.2010.08.038; PMID: 20850176
- Sheltzer JM, Torres EM, Dunham MJ, Amon A. Transcriptional consequences of aneuploidy. Proc Natl Acad Sci USA 2012; 109:12644 - 9; http://dx.doi.org/10.1073/pnas.1209227109; PMID: 22802626
- Yona AH, Manor YS, Herbst RH, Romano GH, Mitchell A, Kupiec M, et al. Chromosomal duplication is a transient evolutionary solution to stress. Proc Natl Acad Sci USA 2012; 109:21010 - 5; http://dx.doi.org/10.1073/pnas.1211150109; PMID: 23197825