346
Views
13
CrossRef citations to date
0
Altmetric
Article Addendum

The versatile Legionella effector protein DrrA

, , , , , , & show all
Pages 72-74 | Received 05 Oct 2010, Accepted 05 Oct 2010, Published online: 01 Jan 2011

References

  • Isberg RR, O'Connor TJ, Heidtman M. The Legionella pneumophila replication vacuole: making a cosy niche inside host cells. Nat Rev Microbiol 2009; 7:13 - 24
  • Brombacher E, Urwyler S, Ragaz C, Weber SS, Kami K, Overduin M, et al. Rab1 guanine nucleotide exchange factor SidM is a major phosphatidylinositol 4-phosphate-binding effector protein of Legionella pneumophila. J Biol Chem 2009; 284:4846 - 4856
  • Machner MP, Isberg RR. Targeting of host Rab GTPase function by the intravacuolar pathogen Legionella pneumophila. Dev Cell 2006; 11:47 - 56
  • Murata T, Delprato A, Ingmundson A, Toomre DK, Lambright DG, Roy CR. The Legionella pneumophila effector protein DrrA is a Rab1 guanine nucleotide-exchange factor. Nat Cell Biol 2006; 8:971 - 977
  • Schoebel S, Oesterlin LK, Blankenfeldt W, Goody RS, Itzen A. RabGDI displacement by DrrA from Legionella is a consequence of its guanine nucleotide exchange activity. Mol Cell 2009; 36:1060 - 1072
  • Suh HY, Lee DW, Lee KH, Ku B, Choi SJ, Woo JS, et al. Structural insights into the dual nucleotide exchange and GDI displacement activity of SidM/DrrA. EMBO J 2010; 29:496 - 504
  • Zhu Y, Hu L, Zhou Y, Yao Q, Liu L, Shao F. Structural mechanism of host Rab1 activation by the bifunctional Legionella type IV effector SidM/DrrA. Proc Natl Acad Sci USA 2010; 107:4699 - 4704
  • Müller MP, Peters H, Blümer J, Blankenfeldt W, Goody RS, Itzen A. The Legionella effector protein DrrA AMPylates the membrane traffic regulator Rab1b. Science 2010; 329:946 - 949
  • Ingmundson A, Delprato A, Lambright DG, Roy CR. Legionella pneumophila proteins that regulate Rab1 membrane cycling. Nature 2007; 450:365 - 369
  • Schoebel S, Blankenfeldt W, Goody RS, Itzen A. High-affinity binding of phosphatidylinositol-4-phosphate by Legionella pneumophila DrrA. EMBO Rep 2010; 11:598 - 604
  • Zerial M, McBride H. Rab proteins as membrane organizers. Nat Rev Mol Cell Biol 2001; 2:107 - 117
  • Stenmark H. Rab GTPases as coordinators of vesicle traffic. Nat Rev Mol Cell Biol 2009; 10:513 - 525
  • Wu YW, Oesterlin LK, Tan KT, Waldmann H, Alexandrov K, Goody RS. Membrane targeting mechanism of Rab GTPases elucidated by semi-synthetic protein probes. Nat Chem Biol 2010; 6:534 - 540
  • Yarbrough ML, Li Y, Kinch LN, Grishin NV, Ball HL, Orth K. AMPylation of Rho GTPases by Vibrio VopS disrupts effector binding and downstream signaling. Science 2009; 323:269 - 272
  • Worby CA, Mattoo S, Kruger RP, Corbeil LB, Koller A, Mendez JC, et al. The fic domain: regulation of cell signaling by adenylylation. Mol Cell 2009; 34:93 - 103
  • Stadtman ER. The story of glutamine synthetase regulation. J Biol Chem 2001; 276:44357 - 44364
  • Wulff K, Mecke D, Holzer H. Mechanism of enzymatic inactivation of glutamine synthetase from E. coli. Biochem Biophys Res Commun 1967; 28:740 - 745
  • Shapiro BM, Stadtman ER. Glutamine synthetase deadenylylating enzyme. Biochem Biophys Res Commun 1968; 30:32 - 37
  • Kingdon HS, Shapiro BM, Stadtman ER. Regulation of glutamine synthetase, VIII. ATP: glutamine synthetase adenylyltransferase, an enzyme that catalyzes alterations in the regulatory properties of glutamine synthetase. Proc Natl Acad Sci USA 1967; 58:1703 - 1710
  • Shapiro BM, Kingdon HS, Stadtman ER. Regulation of glutamine synthetase. VII. Adenylyl glutamine synthetase: a new form of the enzyme with altered regulatory and kinetic properties. Proc Natl Acad Sci USA 1967; 58:642 - 649