The KIBRA-aPKC connection

References

• Kremerskothen J, Plaas C, Büther K, Finger I, Veltel S, Matanis T, et al. Characterization of KIBRA, a novel WW domain-containing protein. Biochem Biophys Res Commun 2003; 300:862 - 7; http://dx.doi.org/10.1016/S0006-291X(02)02945-5; PMID: 12559952
   PubMed Web of Science ®Google Scholar
• Duning K, Schurek EM, Schlüter M, Bayer M, Reinhardt HC, Schwab A, et al. KIBRA modulates directional migration of podocytes. J Am Soc Nephrol 2008; 19:1891 - 903; http://dx.doi.org/10.1681/ASN.2007080916; PMID: 18596123
   PubMed Web of Science ®Google Scholar
• Hilton HN, Stanford PM, Harris J, Oakes SR, Kaplan W, Daly RJ, et al. KIBRA interacts with discoidin domain receptor 1 to modulate collagen-induced signalling. Biochim Biophys Acta 2008; 1783:383-93.
   Google Scholar
• Rosse C, Formstecher E, Boeckeler K, Zhao Y, Kremerskothen J, White MD, et al. An aPKC-exocyst complex controls paxillin phosphorylation and migration through localised JNK1 activation. PLoS Biol 2009; 7:e1000235; http://dx.doi.org/10.1371/journal.pbio.1000235; PMID: 19885391
   PubMed Web of Science ®Google Scholar
• Genevet A, Wehr MC, Brain R, Thompson BJ, Tapon N. Kibra is a regulator of the Salvador/Warts/Hippo signaling network. Dev Cell 2010; 18:300 - 8; http://dx.doi.org/10.1016/j.devcel.2009.12.011; PMID: 20159599
   PubMed Web of Science ®Google Scholar
• Yu J, Zheng Y, Dong J, Klusza S, Deng WM, Pan D. Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded. Dev Cell 2010; 18:288 - 99; http://dx.doi.org/10.1016/j.devcel.2009.12.012; PMID: 20159598
   PubMed Web of Science ®Google Scholar
• Baumgartner R, Poernbacher I, Buser N, Hafen E, Stocker H. The WW domain protein Kibra acts upstream of Hippo in Drosophila. Dev Cell 2010; 18:309 - 16; http://dx.doi.org/10.1016/j.devcel.2009.12.013; PMID: 20159600
   PubMed Web of Science ®Google Scholar
• Grusche FA, Richardson HE, Harvey KF. Upstream regulation of the hippo size control pathway. Curr Biol 2010; 20:R574 - 82; http://dx.doi.org/10.1016/j.cub.2010.05.023; PMID: 20619814
   PubMed Web of Science ®Google Scholar
• Genevet A, Tapon N. The Hippo pathway and apico-basal cell polarity. Biochem J 2011; 436:213 - 24; http://dx.doi.org/10.1042/BJ20110217; PMID: 21568941
   PubMed Web of Science ®Google Scholar
• Xiao L, Chen Y, Ji M, Volle DJ, Lewis RE, Tsai MY, et al. KIBRA protein phosphorylation is regulated by mitotic kinase aurora and protein phosphatase 1. J Biol Chem 2011; 286:36304 - 15; http://dx.doi.org/10.1074/jbc.M111.246850; PMID: 21878642
   PubMed Web of Science ®Google Scholar
• Xiao L, Chen Y, Ji M, Dong J. KIBRA regulates Hippo signaling activity via interactions with large tumor suppressor kinases. J Biol Chem 2011; 286:7788 - 96; http://dx.doi.org/10.1074/jbc.M110.173468; PMID: 21233212
   PubMed Web of Science ®Google Scholar
• Papassotiropoulos A, Stephan DA, Huentelman MJ, Hoerndli FJ, Craig DW, Pearson JV, et al. Common Kibra alleles are associated with human memory performance. Science 2006; 314:475 - 8; http://dx.doi.org/10.1126/science.1129837; PMID: 17053149
   PubMed Web of Science ®Google Scholar
• Schneider A, Huentelman MJ, Kremerskothen J, Duning K, Spoelgen R, Nikolich K. KIBRA: A New Gateway to Learning and Memory?. Front Aging Neurosci 2010; 2:4; PMID: 20552044
   PubMedGoogle Scholar
• Makuch L, Volk L, Anggono V, Johnson RC, Yu Y, Duning K, et al. Regulation of AMPA receptor function by the human memory-associated gene KIBRA. Neuron 2011; 71:1022 - 9; http://dx.doi.org/10.1016/j.neuron.2011.08.017; PMID: 21943600
   PubMed Web of Science ®Google Scholar
• Yoshihama Y, Sasaki K, Horikoshi Y, Suzuki A, Ohtsuka T, Hakuno F, et al. KIBRA suppresses apical exocytosis through inhibition of aPKC kinase activity in epithelial cells. Curr Biol 2011; 21:705 - 11; http://dx.doi.org/10.1016/j.cub.2011.03.029; PMID: 21497093
   PubMed Web of Science ®Google Scholar
• Traer CJ, Rutherford AC, Palmer KJ, Wassmer T, Oakley J, Attar N, et al. SNX4 coordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartment. Nat Cell Biol 2007; 9:1370 - 80; http://dx.doi.org/10.1038/ncb1656; PMID: 17994011
   PubMed Web of Science ®Google Scholar
• Johannsen S, Duning K, Pavenstädt H, Kremerskothen J, Boeckers TM. Temporal-spatial expression and novel biochemical properties of the memory-related protein KIBRA. Neuroscience 2008; 155:1165 - 73; http://dx.doi.org/10.1016/j.neuroscience.2008.06.054; PMID: 18672031
   PubMed Web of Science ®Google Scholar
• Hung AY, Sheng M. PDZ domains: structural modules for protein complex assembly. J Biol Chem 2002; 277:5699 - 702; http://dx.doi.org/10.1074/jbc.R100065200; PMID: 11741967
   PubMed Web of Science ®Google Scholar
• Weisz OA, Rodriguez-Boulan E. Apical trafficking in epithelial cells: signals, clusters and motors. J Cell Sci 2009; 122:4253 - 66; http://dx.doi.org/10.1242/jcs.032615; PMID: 19923269
   PubMed Web of Science ®Google Scholar
• Vega-Salas DE, Salas PJ, Rodriguez-Boulan E. Exocytosis of vacuolar apical compartment (VAC): a cell-cell contact controlled mechanism for the establishment of the apical plasma membrane domain in epithelial cells. J Cell Biol 1988; 107:1717 - 28; http://dx.doi.org/10.1083/jcb.107.5.1717; PMID: 3053735
   PubMed Web of Science ®Google Scholar
• Zhang H, Macara IG. The PAR-6 polarity protein regulates dendritic spine morphogenesis through p190 RhoGAP and the Rho GTPase. Dev Cell 2008; 14:216 - 26; http://dx.doi.org/10.1016/j.devcel.2007.11.020; PMID: 18267090
   PubMed Web of Science ®Google Scholar
• Zhang H, Macara IG. The polarity protein PAR-3 and TIAM1 cooperate in dendritic spine morphogenesis. Nat Cell Biol 2006; 8:227 - 37; http://dx.doi.org/10.1038/ncb1368; PMID: 16474385
   PubMed Web of Science ®Google Scholar
• Suzuki A, Ohno S. The PAR-aPKC system: lessons in polarity. J Cell Sci 2006; 119:979 - 87; http://dx.doi.org/10.1242/jcs.02898; PMID: 16525119
   PubMed Web of Science ®Google Scholar
• Du D, Xu F, Yu L, Zhang C, Lu X, Yuan H, et al. The tight junction protein, occludin, regulates the directional migration of epithelial cells. Dev Cell 2010; 18:52 - 63; http://dx.doi.org/10.1016/j.devcel.2009.12.008; PMID: 20152177
   PubMed Web of Science ®Google Scholar
• Büther K, Plaas C, Barnekow A, Kremerskothen J. KIBRA is a novel substrate for protein kinase Czeta. Biochem Biophys Res Commun 2004; 317:703 - 7; http://dx.doi.org/10.1016/j.bbrc.2004.03.107; PMID: 15081397
   PubMed Web of Science ®Google Scholar
• Horikoshi Y, Suzuki A, Yamanaka T, Sasaki K, Mizuno K, Sawada H, et al. Interaction between PAR-3 and the aPKC-PAR-6 complex is indispensable for apical domain development of epithelial cells. J Cell Sci 2009; 122:1595 - 606; http://dx.doi.org/10.1242/jcs.043174; PMID: 19401335
   PubMed Web of Science ®Google Scholar
• Hirai T, Niino YS, Chida K. PKC ζ II, a small molecule of protein kinase C ζ, specifically expressed in the mouse brain. Neurosci Lett 2003; 348:151 - 4; http://dx.doi.org/10.1016/S0304-3940(03)00780-8; PMID: 12932816
   PubMed Web of Science ®Google Scholar
• Hernandez AI, Blace N, Crary JF, Serrano PA, Leitges M, Libien JM, et al. Protein kinase M ζ synthesis from a brain mRNA encoding an independent protein kinase C ζ catalytic domain. Implications for the molecular mechanism of memory. J Biol Chem 2003; 278:40305 - 16; http://dx.doi.org/10.1074/jbc.M307065200; PMID: 12857744
   PubMed Web of Science ®Google Scholar
• Ling DS, Benardo LS, Serrano PA, Blace N, Kelly MT, Crary JF, et al. Protein kinase Mzeta is necessary and sufficient for LTP maintenance. Nat Neurosci 2002; 5:295 - 6; http://dx.doi.org/10.1038/nn829; PMID: 11914719
   PubMed Web of Science ®Google Scholar
• Ling DS, Benardo LS, Sacktor TC. Protein kinase Mzeta enhances excitatory synaptic transmission by increasing the number of active postsynaptic AMPA receptors. Hippocampus 2006; 16:443 - 52; http://dx.doi.org/10.1002/hipo.20171; PMID: 16463388
   PubMed Web of Science ®Google Scholar
• Yao Y, Kelly MT, Sajikumar S, Serrano P, Tian D, Bergold PJ, et al. PKM ζ maintains late long-term potentiation by N-ethylmaleimide-sensitive factor/GluR2-dependent trafficking of postsynaptic AMPA receptors. J Neurosci 2008; 28:7820 - 7; http://dx.doi.org/10.1523/JNEUROSCI.0223-08.2008; PMID: 18667614
   PubMed Web of Science ®Google Scholar
• Burgess JD, Pedraza O, Graff-Radford NR, Hirpa M, Zou F, Miles R, et al. Association of common KIBRA variants with episodic memory and AD risk. Neurobiol Aging 2011; 32:557 e1-9.
   Google Scholar
• Corneveaux JJ, Liang WS, Reiman EM, Webster JA, Myers AJ, Zismann VL, et al. Evidence for an association between KIBRA and late-onset Alzheimer’s disease. Neurobiol Aging 2010; 31:901 - 9; http://dx.doi.org/10.1016/j.neurobiolaging.2008.07.014; PMID: 18789830
   PubMed Web of Science ®Google Scholar
• Balklava Z, Pant S, Fares H, Grant BD. Genome-wide analysis identifies a general requirement for polarity proteins in endocytic traffic. Nat Cell Biol 2007; 9:1066 - 73; http://dx.doi.org/10.1038/ncb1627; PMID: 17704769
   PubMed Web of Science ®Google Scholar
• Bryant DM, Datta A, Rodríguez-Fraticelli AE, Peränen J, Martín-Belmonte F, Mostov KE. A molecular network for de novo generation of the apical surface and lumen. Nat Cell Biol 2010; 12:1035 - 45; http://dx.doi.org/10.1038/ncb2106; PMID: 20890297
   PubMed Web of Science ®Google Scholar
• Chen XW, Leto D, Xiao J, Goss J, Wang Q, Shavit JA, et al. Exocyst function is regulated by effector phosphorylation. Nat Cell Biol 2011; 13:580 - 8; http://dx.doi.org/10.1038/ncb2226; PMID: 21516108
   PubMed Web of Science ®Google Scholar