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Commentary

Estrogen receptor (ER)-mediated activation by endocrine disrupting chemicals (EDCs)

A comparison between synthetic and natural compounds

, &
Article: e27197 | Received 06 Sep 2013, Accepted 13 Nov 2013, Published online: 22 Nov 2013

References

  • Henley DV, Korach KS. Physiological effects and mechanisms of action of endocrine disrupting chemicals that alter estrogen signaling. Hormones (Athens) 2010; 9:191 - 205; PMID: 20688617
  • Diamanti-Kandarakis E, Bourguignon JP, Giudice LC, Hauser R, Prins GS, Soto AM, Zoeller RT, Gore AC. Endocrine-disrupting chemicals: an Endocrine Society scientific statement. Endocr Rev 2009; 30:293 - 342; http://dx.doi.org/10.1210/er.2009-0002; PMID: 19502515
  • Golden RJ, Noller KL, Titus-Ernstoff L, Kaufman RH, Mittendorf R, Stillman R, Reese EA. Environmental endocrine modulators and human health: an assessment of the biological evidence. Crit Rev Toxicol 1998; 28:109 - 227; http://dx.doi.org/10.1080/10408449891344191; PMID: 9557209
  • Hughes CL Jr.. Phytochemical mimicry of reproductive hormones and modulation of herbivore fertility by phytoestrogens. Environ Health Perspect 1988; 78:171 - 4; http://dx.doi.org/10.1289/ehp.8878171; PMID: 3203635
  • Omiecinski CJ, Vanden Heuvel JP, Perdew GH, Peters JM. Xenobiotic metabolism, disposition, and regulation by receptors: from biochemical phenomenon to predictors of major toxicities. Toxicol Sci 2011; 120:Suppl 1 S49 - 75; http://dx.doi.org/10.1093/toxsci/kfq338; PMID: 21059794
  • Hall JM, McDonnell DP. Coregulators in nuclear estrogen receptor action: from concept to therapeutic targeting. Mol Interv 2005; 5:343 - 57; http://dx.doi.org/10.1124/mi.5.6.7; PMID: 16394250
  • Li Y, Luh CJ, Burns KA, Arao Y, Jiang Z, Teng CT, Tice RR, Korach KS. Endocrine-Disrupting Chemicals (EDCs): In Vitro Mechanism of Estrogenic Activation and Differential Effects on ER Target Genes. Environ Health Perspect 2013; 121:459-66, 66e1-6.
  • Wetherill YB, Akingbemi BT, Kanno J, McLachlan JA, Nadal A, Sonnenschein C, Watson CS, Zoeller RT, Belcher SM. In vitro molecular mechanisms of bisphenol A action. Reprod Toxicol 2007; 24:178 - 98; http://dx.doi.org/10.1016/j.reprotox.2007.05.010; PMID: 17628395
  • Rubin BS. Bisphenol A: an endocrine disruptor with widespread exposure and multiple effects. J Steroid Biochem Mol Biol 2011; 127:27 - 34; http://dx.doi.org/10.1016/j.jsbmb.2011.05.002; PMID: 21605673
  • Matsushima A, Liu X, Okada H, Shimohigashi M, Shimohigashi Y. Bisphenol AF is a full agonist for the estrogen receptor ERalpha but a highly specific antagonist for ERbeta. Environ Health Perspect 2010; 118:1267 - 72; http://dx.doi.org/10.1289/ehp.0901819; PMID: 20427257
  • Hewitt SC, Korach KS. Estrogenic activity of bisphenol A and 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane (HPTE) demonstrated in mouse uterine gene profiles. Environ Health Perspect 2011; 119:63 - 70; http://dx.doi.org/10.1289/ehp.1002347; PMID: 20826375
  • Li Y, Burns KA, Arao Y, Luh CJ, Korach KS. Differential estrogenic actions of endocrine-disrupting chemicals bisphenol A, bisphenol AF, and zearalenone through estrogen receptor α and β in vitro. Environ Health Perspect 2012; 120:1029 - 35; http://dx.doi.org/10.1289/ehp.1104689; PMID: 22494775
  • Melnick R, Lucier G, Wolfe M, Hall R, Stancel G, Prins G, Gallo M, Reuhl K, Ho SM, Brown T, et al. Summary of the National Toxicology Program’s report of the endocrine disruptors low-dose peer review. Environ Health Perspect 2002; 110:427 - 31; http://dx.doi.org/10.1289/ehp.02110427; PMID: 11940462
  • Vandenberg LN, Colborn T, Hayes TB, Heindel JJ, Jacobs DR Jr., Lee DH, Shioda T, Soto AM, vom Saal FS, Welshons WV, et al. Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses. Endocr Rev 2012; 33:378 - 455; http://dx.doi.org/10.1210/er.2011-1050; PMID: 22419778
  • Hugo ER, Brandebourg TD, Woo JG, Loftus J, Alexander JW, Ben-Jonathan N. Bisphenol A at environmentally relevant doses inhibits adiponectin release from human adipose tissue explants and adipocytes. Environ Health Perspect 2008; 116:1642 - 7; http://dx.doi.org/10.1289/ehp.11537; PMID: 19079714
  • Makaji E, Raha S, Wade MG, Holloway AC. Effect of environmental contaminants on Beta cell function. Int J Toxicol 2011; 30:410 - 8; http://dx.doi.org/10.1177/1091581811405544; PMID: 21705745
  • Ohta R, Takagi A, Ohmukai H, Marumo H, Ono A, Matsushima Y, Inoue T, Ono H, Kanno J. Ovariectomized mouse uterotrophic assay of 36 chemicals. J Toxicol Sci 2012; 37:879 - 89; http://dx.doi.org/10.2131/jts.37.879; PMID: 23037998
  • Liao C, Liu F, Alomirah H, Loi VD, Mohd MA, Moon HB, Nakata H, Kannan K. Bisphenol S in urine from the United States and seven Asian countries: occurrence and human exposures. Environ Sci Technol 2012; 46:6860 - 6; http://dx.doi.org/10.1021/es301334j; PMID: 22620267
  • Golub MS, Wu KL, Kaufman FL, Li LH, Moran-Messen F, Zeise L, Alexeeff GV, Donald JM. Bisphenol A: developmental toxicity from early prenatal exposure. Birth Defects Res B Dev Reprod Toxicol 2010; 89:441 - 66; http://dx.doi.org/10.1002/bdrb.20275; PMID: 21136531
  • Dang ZC. Dose-dependent effects of soy phyto-oestrogen genistein on adipocytes: mechanisms of action. Obes Rev 2009; 10:342 - 9; http://dx.doi.org/10.1111/j.1467-789X.2008.00554.x; PMID: 19207876
  • Kuiper GG, Lemmen JG, Carlsson B, Corton JC, Safe SH, van der Saag PT, van der Burg B, Gustafsson JA. Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta. Endocrinology 1998; 139:4252 - 63; http://dx.doi.org/10.1210/en.139.10.4252; PMID: 9751507
  • Nagaraju GP, Zafar SF, El-Rayes BF. Pleiotropic effects of genistein in metabolic, inflammatory, and malignant diseases. Nutr Rev 2013; 71:562 - 72; http://dx.doi.org/10.1111/nure.12044; PMID: 23865800
  • Birt DF, Hendrich S, Wang W. Dietary agents in cancer prevention: flavonoids and isoflavonoids. Pharmacol Ther 2001; 90:157 - 77; http://dx.doi.org/10.1016/S0163-7258(01)00137-1; PMID: 11578656
  • Adjakly M, Ngollo M, Boiteux JP, Bignon YJ, Guy L, Bernard-Gallon D. Genistein and daidzein: different molecular effects on prostate cancer. Anticancer Res 2013; 33:39 - 44; PMID: 23267126
  • Si H, Liu D. Phytochemical genistein in the regulation of vascular function: new insights. Curr Med Chem 2007; 14:2581 - 9; http://dx.doi.org/10.2174/092986707782023325; PMID: 17979711