Sulforaphane causes a major epigenetic repression of myostatin in porcine satellite cells

References

• Lunney JK. Advances in swine biomedical model genomics. Int J Biol Sci 2007; 3:179 - 84; http://dx.doi.org/10.7150/ijbs.3.179; PMID: 17384736
   PubMed Web of Science ®Google Scholar
• Wagers AJ, Conboy IM. Cellular and molecular signatures of muscle regeneration: current concepts and controversies in adult myogenesis. Cell 2005; 122:659 - 67; http://dx.doi.org/10.1016/j.cell.2005.08.021; PMID: 16143100
   PubMed Web of Science ®Google Scholar
• Kuang S, Gillespie MA, Rudnicki MA. Niche regulation of muscle satellite cell self-renewal and differentiation. Cell Stem Cell 2008; 2:22 - 31; http://dx.doi.org/10.1016/j.stem.2007.12.012; PMID: 18371418
   PubMed Web of Science ®Google Scholar
• Guerrero-Beltrán CE, Calderón-Oliver M, Pedraza-Chaverri J, Chirino YI. Protective effect of sulforaphane against oxidative stress: recent advances. Exp Toxicol Pathol 2012; 64:503 - 8; http://dx.doi.org/10.1016/j.etp.2010.11.005; PMID: 21129940
   PubMed Web of Science ®Google Scholar
• Myzak MC, Karplus PA, Chung FL, Dashwood RH. A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase. Cancer Res 2004; 64:5767 - 74; http://dx.doi.org/10.1158/0008-5472.CAN-04-1326; PMID: 15313918
   PubMed Web of Science ®Google Scholar
• Myzak MC, Hardin K, Wang R, Dashwood RH, Ho E. Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells. Carcinogenesis 2006; 27:811 - 9; http://dx.doi.org/10.1093/carcin/bgi265; PMID: 16280330
   PubMed Web of Science ®Google Scholar
• Myzak MC, Dashwood WM, Orner GA, Ho E, Dashwood RH. Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice. FASEB J 2006; 20:506 - 8; PMID: 16407454
   PubMed Web of Science ®Google Scholar
• Myzak MC, Tong P, Dashwood WM, Dashwood RH, Ho E. Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects. Exp Biol Med (Maywood) 2007; 232:227 - 34; PMID: 17259330
   PubMed Web of Science ®Google Scholar
• McPherron AC, Lee SJ. Double muscling in cattle due to mutations in the myostatin gene. Proc Natl Acad Sci U S A 1997; 94:12457 - 61; http://dx.doi.org/10.1073/pnas.94.23.12457; PMID: 9356471
   PubMed Web of Science ®Google Scholar
• McCroskery S, Thomas M, Maxwell L, Sharma M, Kambadur R. Myostatin negatively regulates satellite cell activation and self-renewal. J Cell Biol 2003; 162:1135 - 47; http://dx.doi.org/10.1083/jcb.200207056; PMID: 12963705
   PubMed Web of Science ®Google Scholar
• Joulia-Ekaza D, Cabello G. The myostatin gene: physiology and pharmacological relevance. Curr Opin Pharmacol 2007; 7:310 - 5; http://dx.doi.org/10.1016/j.coph.2006.11.011; PMID: 17374508
   PubMed Web of Science ®Google Scholar
• Perdiguero E, Sousa-Victor P, Ballestar E, Muñoz-Cánoves P. Epigenetic regulation of myogenesis. Epigenetics 2009; 4:541 - 50; http://dx.doi.org/10.4161/epi.4.8.10258; PMID: 20009536
   PubMed Web of Science ®Google Scholar
• Kelly TK, De Carvalho DD, Jones PA. Epigenetic modifications as therapeutic targets. Nat Biotechnol 2010; 28:1069 - 78; http://dx.doi.org/10.1038/nbt.1678; PMID: 20944599
   PubMed Web of Science ®Google Scholar
• Drummond MJ, Glynn EL, Fry CS, Dhanani S, Volpi E, Rasmussen BB. Essential amino acids increase microRNA-499, -208b, and -23a and downregulate myostatin and myocyte enhancer factor 2C mRNA expression in human skeletal muscle. J Nutr 2009; 139:2279 - 84; http://dx.doi.org/10.3945/jn.109.112797; PMID: 19828686
   PubMed Web of Science ®Google Scholar
• Allen DL, Loh AS. Posttranscriptional mechanisms involving microRNA-27a and b contribute to fast-specific and glucocorticoid-mediated myostatin expression in skeletal muscle. Am J Physiol Cell Physiol 2011; 300:C124 - 37; http://dx.doi.org/10.1152/ajpcell.00142.2010; PMID: 20980549
   PubMedGoogle Scholar
• Allen DL, Unterman TG. Regulation of myostatin expression and myoblast differentiation by FoxO and SMAD transcription factors. Am J Physiol Cell Physiol 2007; 292:C188 - 99; http://dx.doi.org/10.1152/ajpcell.00542.2005; PMID: 16885393
   PubMed Web of Science ®Google Scholar
• Ma K, Mallidis C, Artaza J, Taylor W, Gonzalez-Cadavid N, Bhasin S. Characterization of 5′-regulatory region of human myostatin gene: regulation by dexamethasone in vitro. Am J Physiol Endocrinol Metab 2001; 281:E1128 - 36; PMID: 11701425
   PubMed Web of Science ®Google Scholar
• Krauss RS. Evolutionary conservation in myoblast fusion. Nat Genet 2007; 39:704 - 5; http://dx.doi.org/10.1038/ng0607-704; PMID: 17534361
   PubMed Web of Science ®Google Scholar
• Singh SV, Srivastava SK, Choi S, Lew KL, Antosiewicz J, Xiao D, et al. Sulforaphane-induced cell death in human prostate cancer cells is initiated by reactive oxygen species. J Biol Chem 2005; 280:19911 - 24; http://dx.doi.org/10.1074/jbc.M412443200; PMID: 15764812
   PubMed Web of Science ®Google Scholar
• Pledgie-Tracy A, Sobolewski MD, Davidson NE. Sulforaphane induces cell type-specific apoptosis in human breast cancer cell lines. Mol Cancer Ther 2007; 6:1013 - 21; http://dx.doi.org/10.1158/1535-7163.MCT-06-0494; PMID: 17339367
   PubMed Web of Science ®Google Scholar
• Utriainen P, Liu J, Kuulasmaa T, Voutilainen R. Inhibition of DNA methylation increases follistatin expression and secretion in the human adrenocortical cell line NCI-H295R. J Endocrinol 2006; 188:305 - 10; http://dx.doi.org/10.1677/joe.1.06392; PMID: 16461556
   PubMed Web of Science ®Google Scholar
• Iezzi S, Cossu G, Nervi C, Sartorelli V, Puri PL. Stage-specific modulation of skeletal myogenesis by inhibitors of nuclear deacetylases. Proc Natl Acad Sci U S A 2002; 99:7757 - 62; http://dx.doi.org/10.1073/pnas.112218599; PMID: 12032356
   PubMed Web of Science ®Google Scholar
• Iezzi S, Di Padova M, Serra C, Caretti G, Simone C, Maklan E, et al. Deacetylase inhibitors increase muscle cell size by promoting myoblast recruitment and fusion through induction of follistatin. Dev Cell 2004; 6:673 - 84; http://dx.doi.org/10.1016/S1534-5807(04)00107-8; PMID: 15130492
   PubMed Web of Science ®Google Scholar
• Gomyo Y, Sasaki J, Branch C, Roth JA, Mukhopadhyay T. 5-aza-2′-deoxycytidine upregulates caspase-9 expression cooperating with p53-induced apoptosis in human lung cancer cells. Oncogene 2004; 23:6779 - 87; http://dx.doi.org/10.1038/sj.onc.1207381; PMID: 15273730
   PubMed Web of Science ®Google Scholar
• Singh AV, Xiao D, Lew KL, Dhir R, Singh SV. Sulforaphane induces caspase-mediated apoptosis in cultured PC-3 human prostate cancer cells and retards growth of PC-3 xenografts in vivo. Carcinogenesis 2004; 25:83 - 90; http://dx.doi.org/10.1093/carcin/bgg178; PMID: 14514658
   PubMed Web of Science ®Google Scholar
• Lee SJ. Regulation of muscle mass by myostatin. Annu Rev Cell Dev Biol 2004; 20:61 - 86; http://dx.doi.org/10.1146/annurev.cellbio.20.012103.135836; PMID: 15473835
   PubMed Web of Science ®Google Scholar
• Amthor H, Nicholas G, McKinnell I, Kemp CF, Sharma M, Kambadur R, et al. Follistatin complexes Myostatin and antagonises Myostatin-mediated inhibition of myogenesis. Dev Biol 2004; 270:19 - 30; http://dx.doi.org/10.1016/j.ydbio.2004.01.046; PMID: 15136138
   PubMed Web of Science ®Google Scholar
• Valencia-Sanchez MA, Liu J, Hannon GJ, Parker R. Control of translation and mRNA degradation by miRNAs and siRNAs. Genes Dev 2006; 20:515 - 24; http://dx.doi.org/10.1101/gad.1399806; PMID: 16510870
   PubMed Web of Science ®Google Scholar
• Callis TE, Pandya K, Seok HY, Tang RH, Tatsuguchi M, Huang ZP, et al. MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice. J Clin Invest 2009; 119:2772 - 86; http://dx.doi.org/10.1172/JCI36154; PMID: 19726871
   PubMed Web of Science ®Google Scholar
• Bell ML, Buvoli M, Leinwand LA. Uncoupling of expression of an intronic microRNA and its myosin host gene by exon skipping. Mol Cell Biol 2010; 30:1937 - 45; http://dx.doi.org/10.1128/MCB.01370-09; PMID: 20154144
   PubMed Web of Science ®Google Scholar
• Bendixen E, Danielsen M, Larsen K, Bendixen C. Advances in porcine genomics and proteomics--a toolbox for developing the pig as a model organism for molecular biomedical research. Brief Funct Genomics 2010; 9:208 - 19; http://dx.doi.org/10.1093/bfgp/elq004; PMID: 20495211
   PubMed Web of Science ®Google Scholar
• Malaguti M, Angeloni C, Garatachea N, Baldini M, Leoncini E, Collado PS, et al. Sulforaphane treatment protects skeletal muscle against damage induced by exhaustive exercise in rats. J Appl Physiol 2009; 107:1028 - 36; http://dx.doi.org/10.1152/japplphysiol.00293.2009; PMID: 19713431
   PubMed Web of Science ®Google Scholar
• Zhou H, Brockington M, Jungbluth H, Monk D, Stanier P, Sewry CA, et al. Epigenetic allele silencing unveils recessive RYR1 mutations in core myopathies. Am J Hum Genet 2006; 79:859 - 68; http://dx.doi.org/10.1086/508500; PMID: 17033962
   PubMed Web of Science ®Google Scholar
• Meeran SM, Patel SN, Tollefsbol TO. Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines. PLoS One 2010; 5:e11457; http://dx.doi.org/10.1371/journal.pone.0011457; PMID: 20625516
   PubMed Web of Science ®Google Scholar
• Hsu A, Wong CP, Yu Z, Williams DE, Dashwood RH, Ho E. Promoter de-methylation of cyclin D2 by sulforaphane in prostate cancer cells. Clin Epigenetics 2011; 3:3; http://dx.doi.org/10.1186/1868-7083-3-3; PMID: 22303414
   PubMed Web of Science ®Google Scholar
• Ping Z, Liu W, Kang Z, Cai J, Wang Q, Cheng N, et al. Sulforaphane protects brains against hypoxic-ischemic injury through induction of Nrf2-dependent phase 2 enzyme. Brain Res 2010; 1343:178 - 85; http://dx.doi.org/10.1016/j.brainres.2010.04.036; PMID: 20417626
   PubMed Web of Science ®Google Scholar
• Dashwood RH, Ho E. Dietary histone deacetylase inhibitors: from cells to mice to man. Semin Cancer Biol 2007; 17:363 - 9; http://dx.doi.org/10.1016/j.semcancer.2007.04.001; PMID: 17555985
   PubMed Web of Science ®Google Scholar
• Park JH, Jung Y, Kim TY, Kim SG, Jong HS, Lee JW, et al. Class I histone deacetylase-selective novel synthetic inhibitors potently inhibit human tumor proliferation. Clin Cancer Res 2004; 10:5271 - 81; http://dx.doi.org/10.1158/1078-0432.CCR-03-0709; PMID: 15297431
   PubMed Web of Science ®Google Scholar
• Lee SJ, Lee YS, Zimmers TA, Soleimani A, Matzuk MM, Tsuchida K, et al. Regulation of muscle mass by follistatin and activins. Mol Endocrinol 2010; 24:1998 - 2008; http://dx.doi.org/10.1210/me.2010-0127; PMID: 20810712
   PubMed Web of Science ®Google Scholar
• Han DS, Huang HP, Wang TG, Hung MY, Ke JY, Chang KT, et al. Transcription activation of myostatin by trichostatin A in differentiated C2C12 myocytes via ASK1-MKK3/4/6-JNK and p38 mitogen-activated protein kinase pathways. J Cell Biochem 2010; 111:564 - 73; http://dx.doi.org/10.1002/jcb.22740; PMID: 20568119
   PubMed Web of Science ®Google Scholar
• Cho JS, Moon YM, Park IH, Um JY, Moon JH, Park SJ, et al. Epigenetic regulation of myofibroblast differentiation and extracellular matrix production in nasal polyp-derived fibroblasts. Clin Exp Allergy 2012; 42:872 - 82; http://dx.doi.org/10.1111/j.1365-2222.2011.03931.x; PMID: 22239687
   PubMed Web of Science ®Google Scholar
• Liu X, Wang J, Li R, Yang X, Sun Q, Albrecht E, et al. Maternal dietary protein affects transcriptional regulation of myostatin gene distinctively at weaning and finishing stages in skeletal muscle of Meishan pigs. Epigenetics 2011; 6:899 - 907; http://dx.doi.org/10.4161/epi.6.7.16005; PMID: 21597337
   PubMed Web of Science ®Google Scholar
• Saito Y, Liang G, Egger G, Friedman JM, Chuang JC, Coetzee GA, et al. Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell 2006; 9:435 - 43; http://dx.doi.org/10.1016/j.ccr.2006.04.020; PMID: 16766263
   PubMed Web of Science ®Google Scholar
• Wiklund ED, Bramsen JB, Hulf T, Dyrskjøt L, Ramanathan R, Hansen TB, et al. Coordinated epigenetic repression of the miR-200 family and miR-205 in invasive bladder cancer. Int J Cancer 2011; 128:1327 - 34; http://dx.doi.org/10.1002/ijc.25461; PMID: 20473948
   PubMed Web of Science ®Google Scholar
• Scott GK, Mattie MD, Berger CE, Benz SC, Benz CC. Rapid alteration of microRNA levels by histone deacetylase inhibition. Cancer Res 2006; 66:1277 - 81; http://dx.doi.org/10.1158/0008-5472.CAN-05-3632; PMID: 16452179
   PubMed Web of Science ®Google Scholar
• Spiller MP, Kambadur R, Jeanplong F, Thomas M, Martyn JK, Bass JJ, et al. The myostatin gene is a downstream target gene of basic helix-loop-helix transcription factor MyoD. Mol Cell Biol 2002; 22:7066 - 82; http://dx.doi.org/10.1128/MCB.22.20.7066-7082.2002; PMID: 12242286
   PubMed Web of Science ®Google Scholar
• ZDS. Zentralverband der Deutschen Schweineproduktion (ZDS): Richtlinie für die Stationsprüfung auf Mastleistung, Schlachtkörperwert und Fleischbeschaffenheit beim Schwein. 2003.
   Google Scholar
• Mau M, Oksbjerg N, Rehfeldt C. Establishment and conditions for growth and differentiation of a myoblast cell line derived from the semimembranosus muscle of newborn piglets. In Vitro Cell Dev Biol Anim 2008; 44:1 - 5; http://dx.doi.org/10.1007/s11626-007-9069-6; PMID: 18074188
   PubMed Web of Science ®Google Scholar
• Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP, Burge CB. Prediction of mammalian microRNA targets. Cell 2003; 115:787 - 98; http://dx.doi.org/10.1016/S0092-8674(03)01018-3; PMID: 14697198
   PubMed Web of Science ®Google Scholar
• Rozen S, Skaletsky H. Primer3 on the WWW for general users and for biologist programmers. Methods Mol Biol 2000; 132:365 - 86; PMID: 10547847
   PubMedGoogle Scholar
• Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001; 25:402 - 8; http://dx.doi.org/10.1006/meth.2001.1262; PMID: 11846609
   PubMed Web of Science ®Google Scholar
• Uddin MJ, Cinar MU, Tesfaye D, Looft C, Tholen E, Schellander K. Age-related changes in relative expression stability of commonly used housekeeping genes in selected porcine tissues. BMC Res Notes 2011; 4:441; http://dx.doi.org/10.1186/1756-0500-4-441; PMID: 22023805
   PubMedGoogle Scholar
• Fan H, Cinar MU, Phatsara C, Tesfaye D, Tholen E, Looft C, et al. Molecular mechanism underlying the differential MYF6 expression in postnatal skeletal muscle of Duroc and Pietrain breeds. Gene 2011; 486:8 - 14; http://dx.doi.org/10.1016/j.gene.2011.06.031; PMID: 21749918
   PubMed Web of Science ®Google Scholar
• Li LC, Dahiya R. MethPrimer: designing primers for methylation PCRs. Bioinformatics 2002; 18:1427 - 31; http://dx.doi.org/10.1093/bioinformatics/18.11.1427; PMID: 12424112
   PubMed Web of Science ®Google Scholar
• Marshall OJ. PerlPrimer: cross-platform, graphical primer design for standard, bisulphite and real-time PCR. Bioinformatics 2004; 20:2471 - 2; http://dx.doi.org/10.1093/bioinformatics/bth254; PMID: 15073005
   PubMed Web of Science ®Google Scholar
• Kumaki Y, Oda M, Okano M. QUMA: quantification tool for methylation analysis. Nucleic Acids Res 2008; 36:Web Server issue W170-5; http://dx.doi.org/10.1093/nar/gkn294; PMID: 18487274
   PubMedGoogle Scholar