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Brief Report

HARP preferentially co-purifies with RPA bound to DNA-PK and blocks RPA phosphorylation

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Pages 693-697 | Received 06 Feb 2014, Accepted 20 Feb 2014, Published online: 24 Feb 2014

References

  • Yusufzai T, Kadonaga JT. HARP is an ATP-driven annealing helicase. Science 2008; 322:748 - 50; http://dx.doi.org/10.1126/science.1161233; PMID: 18974355
  • Lao Y, Lee CG, Wold MS. Replication protein A interactions with DNA. 2. Characterization of double-stranded DNA-binding/helix-destabilization activities and the role of the zinc-finger domain in DNA interactions. Biochemistry 1999; 38:3974 - 84; http://dx.doi.org/10.1021/bi982371m; PMID: 10194309
  • Yusufzai T, Kong X, Yokomori K, Kadonaga JT. The annealing helicase HARP is recruited to DNA repair sites via an interaction with RPA. Genes Dev 2009; 23:2400 - 4; http://dx.doi.org/10.1101/gad.1831509; PMID: 19793863
  • Yuan J, Ghosal G, Chen J. The annealing helicase HARP protects stalled replication forks. Genes Dev 2009; 23:2394 - 9; http://dx.doi.org/10.1101/gad.1836409; PMID: 19793864
  • Ciccia A, Bredemeyer AL, Sowa ME, Terret ME, Jallepalli PV, Harper JW, Elledge SJ. The SIOD disorder protein SMARCAL1 is an RPA-interacting protein involved in replication fork restart. Genes Dev 2009; 23:2415 - 25; http://dx.doi.org/10.1101/gad.1832309; PMID: 19793862
  • Bansbach CE, Bétous R, Lovejoy CA, Glick GG, Cortez D. The annealing helicase SMARCAL1 maintains genome integrity at stalled replication forks. Genes Dev 2009; 23:2405 - 14; http://dx.doi.org/10.1101/gad.1839909; PMID: 19793861
  • Postow L, Woo EM, Chait BT, Funabiki H. Identification of SMARCAL1 as a component of the DNA damage response. J Biol Chem 2009; 284:35951 - 61; http://dx.doi.org/10.1074/jbc.M109.048330; PMID: 19841479
  • Boerkoel CF, Takashima H, John J, Yan J, Stankiewicz P, Rosenbarker L, André JL, Bogdanovic R, Burguet A, Cockfield S, et al. Mutant chromatin remodeling protein SMARCAL1 causes Schimke immuno-osseous dysplasia. Nat Genet 2002; 30:215 - 20; http://dx.doi.org/10.1038/ng821; PMID: 11799392
  • Simon AJ, Lev A, Jeison M, Borochowitz ZU, Korn D, Lerenthal Y, Somech R. Novel SMARCAL1 Bi-allelic Mutations Associated with a Chromosomal Breakage Phenotype in a Severe SIOD Patient. J Clin Immunol 2013; Forthcoming PMID: 24197801
  • Din S, Brill SJ, Fairman MP, Stillman B. Cell-cycle-regulated phosphorylation of DNA replication factor A from human and yeast cells. Genes Dev 1990; 4:968 - 77; http://dx.doi.org/10.1101/gad.4.6.968; PMID: 2200738
  • Dutta A, Stillman B. cdc2 family kinases phosphorylate a human cell DNA replication factor, RPA, and activate DNA replication. EMBO J 1992; 11:2189 - 99; PMID: 1318195
  • Fotedar R, Roberts JM. Cell cycle regulated phosphorylation of RPA-32 occurs within the replication initiation complex. EMBO J 1992; 11:2177 - 87; PMID: 1318194
  • Brush GS, Anderson CW, Kelly TJ. The DNA-activated protein kinase is required for the phosphorylation of replication protein A during simian virus 40 DNA replication. Proc Natl Acad Sci U S A 1994; 91:12520 - 4; http://dx.doi.org/10.1073/pnas.91.26.12520; PMID: 7809070
  • Boubnov NV, Weaver DT. scid cells are deficient in Ku and replication protein A phosphorylation by the DNA-dependent protein kinase. Mol Cell Biol 1995; 15:5700 - 6; PMID: 7565721
  • Henricksen LA, Carter T, Dutta A, Wold MS. Phosphorylation of human replication protein A by the DNA-dependent protein kinase is involved in the modulation of DNA replication. Nucleic Acids Res 1996; 24:3107 - 12; http://dx.doi.org/10.1093/nar/24.15.3107; PMID: 8760901
  • Liaw H, Lee D, Myung K. DNA-PK-dependent RPA2 hyperphosphorylation facilitates DNA repair and suppresses sister chromatid exchange. PLoS One 2011; 6:e21424; http://dx.doi.org/10.1371/journal.pone.0021424; PMID: 21731742
  • Shao RG, Cao CX, Zhang H, Kohn KW, Wold MS, Pommier Y. Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexes. EMBO J 1999; 18:1397 - 406; http://dx.doi.org/10.1093/emboj/18.5.1397; PMID: 10064605
  • Wang Y, Zhou XY, Wang H, Huq MS, Iliakis G. Roles of replication protein A and DNA-dependent protein kinase in the regulation of DNA replication following DNA damage. J Biol Chem 1999; 274:22060 - 4; http://dx.doi.org/10.1074/jbc.274.31.22060; PMID: 10419533
  • Oakley GG, Patrick SM, Yao J, Carty MP, Turchi JJ, Dixon K. RPA phosphorylation in mitosis alters DNA binding and protein-protein interactions. Biochemistry 2003; 42:3255 - 64; http://dx.doi.org/10.1021/bi026377u; PMID: 12641457
  • Couch FB, Bansbach CE, Driscoll R, Luzwick JW, Glick GG, Bétous R, Carroll CM, Jung SY, Qin J, Cimprich KA, et al. ATR phosphorylates SMARCAL1 to prevent replication fork collapse. Genes Dev 2013; 27:1610 - 23; http://dx.doi.org/10.1101/gad.214080.113; PMID: 23873943
  • Carroll C, Bansbach CE, Zhao R, Jung SY, Qin J, Cortez D. Phosphorylation of a C-terminal auto-inhibitory domain increases SMARCAL1 activity. Nucleic Acids Res 2014; 42:918 - 25; http://dx.doi.org/10.1093/nar/gkt929; PMID: 24150942
  • Bétous R, Glick GG, Zhao R, Cortez D. Identification and characterization of SMARCAL1 protein complexes. PLoS One 2013; 8:e63149; http://dx.doi.org/10.1371/journal.pone.0063149; PMID: 23671665
  • Vidal-Eychenié S, Décaillet C, Basbous J, Constantinou A. DNA structure-specific priming of ATR activation by DNA-PKcs. J Cell Biol 2013; 202:421 - 9; http://dx.doi.org/10.1083/jcb.201304139; PMID: 23897887
  • Nakatani Y, Ogryzko V. Immunoaffinity purification of mammalian protein complexes. Methods Enzymol 2003; 370:430 - 44; http://dx.doi.org/10.1016/S0076-6879(03)70037-8; PMID: 14712665