A longitudinal study of epigenetic variation in twins

References

• Jaenisch R, Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet 2003; 33:245 - 254
   PubMed Web of Science ®Google Scholar
• Henikoff S, Matzke MA. Exploring and explaining epigenetic effects. Trends Genet 1997; 13:293 - 295
   PubMed Web of Science ®Google Scholar
• Dolinoy DC, Weidman JR, Jirtle RL. Epigenetic gene regulation: linking early developmental environment to adult disease. Reprod Toxicol 2007; 23:297 - 307
   PubMed Web of Science ®Google Scholar
• Kerkel K, Spadola A, Yuan E, Kosek J, Jiang L, Hod E, et al. Genomic surveys by methylation-sensitive SNP analysis identify sequence-dependent allele-specific DNA methylation. Nat Genet 2008; 40:904 - 908
   PubMed Web of Science ®Google Scholar
• Schalkwyk LC, Meaburn EL, Smith R, Dempster EL, Jeffries AR, Davies MN, et al. Allelic Skewing of DNA Methylation Is Widespread across the Genome. Am J Hum Genet 2010; 86:196 - 212
   PubMed Web of Science ®Google Scholar
• Ushijima T, Watanabe N, Okochi E, Kaneda A, Sugimura T, Miyamoto K. Fidelity of the methylation pattern and its variation in the genome. Genome Res 2003; 13:868 - 874
   PubMed Web of Science ®Google Scholar
• Chow JC, Yen Z, Ziesche SM, Brown CJ. Silencing of the mammalian X chromosome. Annu Rev Genomics Hum Genet 2005; 6:69 - 92
   PubMed Web of Science ®Google Scholar
• Delaval K, Feil R. Epigenetic regulation of mammalian genomic imprinting. Curr Opin Genet Dev 2004; 14:188 - 195
   PubMed Web of Science ®Google Scholar
• Jahner D, Stuhlmann H, Stewart CL, Harbers K, Lohler J, Simon I, et al. De novo methylation and expression of retroviral genomes during mouse embryogenesis. Nature 1982; 298:623 - 628
   PubMed Web of Science ®Google Scholar
• Hatchwell E, Greally JM. The potential role of epigenomic dysregulation in complex human disease. Trends Genet 2007; 23:588 - 595
   PubMed Web of Science ®Google Scholar
• Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007; 128:683 - 692
   PubMed Web of Science ®Google Scholar
• Feinberg AP. Phenotypic plasticity and the epigenetics of human disease. Nature 2007; 447:433 - 440
   PubMed Web of Science ®Google Scholar
• Mill J, Tang T, Kaminsky Z, Khare T, Yazdanpanah S, Bouchard L, et al. Epigenomic profiling reveals DNAmethylation changes associated with major psychosis. Am J Hum Genet 2008; 82:696 - 711
   PubMed Web of Science ®Google Scholar
• Mill J, Petronis A. Molecular studies of major depressive disorder: the epigenetic perspective. Mol Psychiatry 2007; 12:799 - 814
   PubMed Web of Science ®Google Scholar
• Renthal W, Nestler EJ. Epigenetic mechanisms in drug addiction. Trends Mol Med 2008; 14:341 - 350
   PubMed Web of Science ®Google Scholar
• Mill J, Petronis A. Pre- and peri-natal environmental risks for attention-deficit hyperactivity disorder (ADHD): the potential role of epigenetic processes in mediating susceptibility. J Child Psychol Psychiatry 2008; 49:1020 - 1030
   PubMed Web of Science ®Google Scholar
• Schanen NC. Epigenetics of autism spectrum disorders. Hum Mol Genet 2006; 15:138 - 150
   PubMed Web of Science ®Google Scholar
• Plomin R, DeFries JC, McClearn GE, McGuffin P. Behavioral Genetics 2008; New York Worth Publishers
   Google Scholar
• Kaminsky ZA, Tang T, Wang SC, Ptak C, Oh GH, Wong AH, et al. DNA methylation profiles in monozygotic and dizygotic twins. Nat Genet 2009; 41:240 - 245
   PubMed Web of Science ®Google Scholar
• Boks MP, Derks EM, Weisenberger DJ, Strengman E, Janson E, Sommer IE, et al. The relationship of DNA methylation with age, gender and genotype in twins and healthy controls. PLoS One 2009; 4:6767
   PubMed Web of Science ®Google Scholar
• Duhl DM, Vrieling H, Miller KA, Wolff GL, Barsh GS. Neomorphic agouti mutations in obese yellow mice. Nat Genet 1994; 8:59 - 65
   PubMed Web of Science ®Google Scholar
• Morgan HD, Sutherland HG, Martin DI, Whitelaw E. Epigenetic inheritance at the agouti locus in the mouse. Nat Genet 1999; 23:314 - 318
   PubMed Web of Science ®Google Scholar
• Fraga MF, Ballestar E, Paz MF, Ropero S, Setien F, Ballestar ML, et al. Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci USA 2005; 102:10604 - 10609
   PubMed Web of Science ®Google Scholar
• Mill J, Dempster E, Caspi A, Williams B, Moffitt T, Craig I. Evidence for monozygotic twin (MZ) discordance in methylation level at two CpG sites in the promoter region of the catechol-O-methyltransferase (COMT) gene. Am J Med Genet B Neuropsychiatr Genet 2006; 141:421 - 425
   Web of Science ®Google Scholar
• Petronis A, Gottesman II, Kan P, Kennedy JL, Basile VS, Paterson AD, et al. Monozygotic twins exhibit numerous epigenetic differences: clues to twin discordance?. Schizophr Bull 2003; 29:169 - 178
   PubMed Web of Science ®Google Scholar
• Heijmans BT, Tobi EW, Stein AD, Putter H, Blauw GJ, Susser ES, et al. Persistent epigenetic differences associated with prenatal exposure to famine in humans. Proc Natl Acad Sci USA 2008; 105:17046 - 17049
   PubMed Web of Science ®Google Scholar
• Bjornsson HT, Sigurdsson MI, Fallin MD, Irizarry RA, Aspelund T, Cui H, et al. Intra-individual change over time in DNA methylation with familial clustering. Jama 2008; 299:2877 - 2883
   PubMed Web of Science ®Google Scholar
• Craig IW. The importance of stress and genetic variation in human aggression. Bioessays 2007; 29:227 - 236
   PubMed Web of Science ®Google Scholar
• Li D, Sham PC, Owen MJ, He L. Meta-analysis shows significant association between dopamine system genes and attention deficit hyperactivity disorder (ADHD). Hum Mol Genet 2006; 15:2276 - 2284
   PubMed Web of Science ®Google Scholar
• Lotrich FE, Pollock BG. Meta-analysis of serotonin transporter polymorphisms and affective disorders. Psychiatr Genet 2004; 14:121 - 129
   PubMed Web of Science ®Google Scholar
• Thapar A, Langley K, Asherson P, Gill M. Gene-environment interplay in attention-deficit hyperactivity disorder and the importance of a developmental perspective. Br J Psychiatry 2007; 190:1 - 3
   PubMed Web of Science ®Google Scholar
• Caspi A, Sugden K, Moffitt TE, Taylor A, Craig IW, Harrington H, et al. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 2003; 301:386 - 389
   PubMed Web of Science ®Google Scholar
• Caspi A, McClay J, Moffitt TE, Mill J, Martin J, Craig IW, et al. Role of genotype in the cycle of violence in maltreated children. Science 2002; 297:851 - 854
   PubMed Web of Science ®Google Scholar
• Plath K, Mlynarczyk-Evans S, Nusinow DA, Panning B. Xist RNA and the mechanism of X chromosome inactivation. Annu Rev Genet 2002; 36:233 - 278
   PubMed Web of Science ®Google Scholar
• Caspi A, Hariri AR, Holmes A, Uher R, Moffitt TE. Genetic sensitivity to the environment: The case of the serotonin transporter gene and its implications for studying complex diseases and traits. Am J Psychiatry 2010; 167:509 - 527
   PubMed Web of Science ®Google Scholar
• Docherty S, Mill J. Epigenetic mechanisms as mediators of environmental risks for psychiatric disorders. Psychiatry 2008; 7:500 - 506
   Google Scholar
• Riggs AD, Xiong Z, Wang L, LeBon JM. Methylation dynamics, epigenetic fidelity and X chromosome structure. Novartis Found Symp 1998; 214:214 - 225
   PubMedGoogle Scholar
• Hendriks RW, Chen ZY, Hinds H, Schuurman RK, Craig IW. An X chromosome inactivation assay based on differential methylation of a CpG island coupled to a VNTR polymorphism at the 5′ end of the monoamine oxidase A gene. Hum Mol Genet 1992; 1:187 - 194
   PubMed Web of Science ®Google Scholar
• Avner P, Heard E. X-chromosome inactivation: counting, choice and initiation. Nat Rev Genet 2001; 2:59 - 67
   PubMed Web of Science ®Google Scholar
• Carrel L, Willard HF. X-inactivation profile reveals extensive variability in X-linked gene expression in females. Nature 2005; 434:400 - 404
   PubMed Web of Science ®Google Scholar
• Pinsonneault JK, Papp AC, Sadee W. Allelic mRNA expression of X-linked monoamine oxidase a (MAOA) in human brain: dissection of epigenetic and genetic factors. Hum Mol Genet 2006; 15:2636 - 2649
   PubMed Web of Science ®Google Scholar
• Craig IW, Harper E, Loat CS. The genetic basis for sex differences in human behaviour: role of the sex chromosomes. Ann Hum Genet 2004; 68:269 - 284
   PubMed Web of Science ®Google Scholar
• Belmont JW. Genetic control of X inactivation and processes leading to X-inactivation skewing. Am J Hum Genet 1996; 58:1101 - 1108
   PubMed Web of Science ®Google Scholar
• Hatakeyama C, Anderson CL, Beever CL, Penaherrera MS, Brown CJ, Robinson WP. The dynamics of X-inactivation skewing as women age. Clin Genet 2004; 66:327 - 332
   PubMed Web of Science ®Google Scholar
• Rosa A, Picchioni MM, Kalidindi S, Loat CS, Knight J, Toulopoulou T, et al. Differential methylation of the X-chromosome is a possible source of discordance for bipolar disorder female monozygotic twins. Am J Med Genet B Neuropsychiatr Genet 2008; 147:459 - 462
   Web of Science ®Google Scholar
• Anway MD, Skinner MK. Epigenetic transgenerational actions of endocrine disruptors. Endocrinology 2006; 147:43 - 49
   PubMed Web of Science ®Google Scholar
• Pembrey ME, Bygren LO, Kaati G, Edvinsson S, Northstone K, Sjostrom M, et al. Sex-specific, maleline transgenerational responses in humans. Eur J Hum Genet 2006; 14:159 - 166
   PubMed Web of Science ®Google Scholar
• Rakyan VK, Chong S, Champ ME, Cuthbert PC, Morgan HD, Luu KV, et al. Transgenerational inheritance of epigenetic states at the murine Axin(Fu) allele occurs after maternal and paternal transmission. Proc Natl Acad Sci USA 2003; 100:2538 - 2543
   PubMed Web of Science ®Google Scholar
• Weaver IC, Cervoni N, Champagne FA, D'Alessio AC, Sharma S, Seckl JR, et al. Epigenetic programming by maternal behavior. Nat Neurosci 2004; 7:847 - 854
   PubMed Web of Science ®Google Scholar
• Cooney CA, Dave AA, Wolff GL. Maternal methyl supplements in mice affect epigenetic variation and DNA methylation of offspring. J Nutr 2002; 132:2393 - 2400
   PubMed Web of Science ®Google Scholar
• Coolen MW, Statham AL, Gardiner-Garden M, Clark SJ. Genomic profiling of CpG methylation and allelic specificity using quantitative high-throughput mass spectrometry: critical evaluation and improvements. Nucleic Acids Res 2007; 35:119
   PubMed Web of Science ®Google Scholar
• Docherty SJ, Davis OS, Haworth CM, Plomin R, Mill J. Bisulfite-based epityping on pooled genomic DNA provides an accurate estimate of average group DNA methylation. Epigenetics Chromatin 2009; 2:3
   PubMed Web of Science ®Google Scholar
• Illingworth R, Kerr A, Desousa D, Jorgensen H, Ellis P, Stalker J, et al. A novel CpG island set identifies tissuespecific methylation at developmental gene loci. PLoS Biol 2008; 6:22
   PubMed Web of Science ®Google Scholar
• Rakyan VK, Down TA, Thorne NP, Flicek P, Kulesha E, Graf S, et al. An integrated resource for genomewide identification and analysis of human tissue-specific differentially methylated regions (tDMRs). Genome Res 2008; 18:1518 - 1529
   PubMed Web of Science ®Google Scholar
• Kitamura E, Igarashi J, Morohashi A, Hida N, Oinuma T, Nemoto N, et al. Analysis of tissue-specific differentially methylated regions (TDMs) in humans. Genomics 2007; 89:326 - 337
   PubMed Web of Science ®Google Scholar
• Moffitt TE. Teen-aged mothers in contemporary Britain. J Child Psychol Psychiatry 2002; 43:727 - 742
   PubMed Web of Science ®Google Scholar
• Trouton A, Spinath FM, Plomin R. Twins early development study (TEDS): a multivariate, longitudinal genetic investigation of language, cognition and behavior problems in childhood. Twin Res 2002; 5:444 - 448
   PubMedGoogle Scholar
• Freeman B, Smith N, Curtis C, Huckett L, Mill J, Craig IW. DNA from buccal swabs recruited by mail: evaluation of storage effects on long-term stability and suitability for multiplex polymerase chain reaction genotyping. Behav Genet 2003; 33:67 - 72
   PubMed Web of Science ®Google Scholar