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Research Paper

HP1α is not necessary for the structural maintenance of centromeric heterochromatin

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Pages 380-387 | Received 02 Aug 2010, Accepted 04 Oct 2010, Published online: 01 Mar 2011

References

  • James TC, Elgin SC. Identification of a nonhistone chromosomal protein associated with heterochromatin in Drosophila melanogaster and its gene. Mol Cell Biol 1986; 6:3862 - 3872
  • Eissenberg JC, James TC, Foster-Hartnett DM, Hartnett T, Ngan V, Elgin SC. Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster. Proc Natl Acad Sci USA 1990; 87:9923 - 9927
  • Eissenberg JC, Elgin SC. The HP1 protein family: getting a grip on chromatin. Curr Opin Genet Dev 2000; 10:204 - 210
  • Kwon SH, Workman JL. The heterochromatin protein 1 (HP1) family: put away a bias toward HP1. Mol Cells 2008; 26:217 - 227
  • Wreggett KA, Hill F, James PS, Hutchings A, Butcher GW, Singh PB. A mammalian homologue of Drosophila heterochromatin protein 1 (HP1) is a component of constitutive heterochromatin. Cytogenet Cell Genet 1994; 66:99 - 103
  • Wang G, Ma A, Chow CM, Horsley D, Brown NR, Cowell IG, et al. Conservation of heterochromatin protein 1 function. Mol Cell Biol 2000; 20:6970 - 6983
  • de Wit E, Greil F, van Steensel B. High-resolution mapping reveals links of HP1 with active and inactive chromatin components. PLoS Genet 2007; 3:38
  • Nonaka N, Kitajima T, Yokobayashi S, Xiao G, Yamamoto M, Grewal SI, et al. Recruitment of cohesin to heterochromatic regions by Swi6/HP1 in fission yeast. Nat Cell Biol 2002; 4:89 - 93
  • Inoue A, Hyle J, Lechner MS, Lahti JM. Perturbation of HP1 localization and chromatin binding ability causes defects in sister-chromatid cohesion. Mutat Res 2008; 657:48 - 55
  • Perrini B, Piacentini L, Fanti L, Altieri F, Chichiarelli S, Berloco M, et al. HP1 controls telomere capping, telomere elongation and telomere silencing by two different mechanisms in Drosophila. Mol Cell 2004; 15:467 - 476
  • Ayoub N, Jeyasekharan AD, Venkitaraman AR. Mobilization and recruitment of HP1: a bimodal response to DNA breakage. Cell Cycle 2009; 8:2945 - 2950
  • Ayoub N, Jeyasekharan AD, Bernal JA, Venkitaraman AR. HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response. Nature 2008; 453:682 - 686
  • Luijsterburg MS, Dinant C, Lans H, Stap J, Wiernasz E, Lagerwerf S, et al. Heterochromatin protein 1 is recruited to various types of DNA damage. J Cell Biol 2009; 185:577 - 586
  • Minc E, Allory Y, Worman HJ, Courvalin JC, Buendia B. Localization and phosphorylation of HP1 proteins during the cell cycle in mammalian cells. Chromosoma 1999; 108:220 - 234
  • Ma J, Hwang KK, Worman HJ, Courvalin JC, Eissenberg JC. Expression and functional analysis of three isoforms of human heterochromatin-associated protein HP1 in Drosophila. Chromosoma 2001; 109:536 - 544
  • Festenstein R, Pagakis SN, Hiragami K, Lyon D, Verreault A, Sekkali B, et al. Modulation of heterochromatin protein 1 dynamics in primary Mammalian cells. Science 2003; 299:719 - 721
  • Lomberk G, Wallrath L, Urrutia R. The Heterochromatin Protein 1 family. Genome Biol 2006; 7:228
  • Norwood LE, Grade SK, Cryderman DE, Hines KA, Furiasse N, Toro R, et al. Conserved properties of HP1(Hsalpha). Gene 2004; 336:37 - 46
  • Lachner M, O'Carroll D, Rea S, Mechtler K, Jenuwein T. Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature 2001; 410:116 - 120
  • Bannister AJ, Zegerman P, Partridge JF, Miska EA, Thomas JO, Allshire RC, et al. Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. Nature 2001; 410:120 - 124
  • Smothers JF, Henikoff S. The hinge and chromo shadow domain impart distinct targeting of HP1-like proteins. Mol Cell Biol 2001; 21:2555 - 2569
  • Smothers JF, Henikoff S. The HP1 chromo shadow domain binds a consensus peptide pentamer. Curr Biol 2000; 10:27 - 30
  • Brasher SV, Smith BO, Fogh RH, Nietlispach D, Thiru A, Nielsen PR, et al. The structure of mouse HP1 suggests a unique mode of single peptide recognition by the shadow chromo domain dimer. EMBO J 2000; 19:1587 - 1597
  • Stewart MD, Li J, Wong J. Relationship between histone H3 lysine 9 methylation, transcription repression and heterochromatin protein 1 recruitment. Mol Cell Biol 2005; 25:2525 - 2538
  • Fuks F, Hurd PJ, Deplus R, Kouzarides T. The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase. Nucleic Acids Res 2003; 31:2305 - 2312
  • Singh PB, Georgatos SD. HP1: facts, open questions and speculation. J Struct Biol 2002; 140:10 - 16
  • Nielsen AL, Oulad-Abdelghani M, Ortiz JA, Remboutsika E, Chambon P, Losson R. Heterochromatin formation in mammalian cells: interaction between histones and HP1 proteins. Mol Cell 2001; 7:729 - 739
  • Dimitri P, Caizzi R, Giordano E, Carmela Accardo M, Lattanzi G, Biamonti G. Constitutive heterochromatin: a surprising variety of expressed sequences. Chromosoma 2009; 118:419 - 435
  • Cheutin T, McNairn AJ, Jenuwein T, Gilbert DM, Singh PB, Misteli T. Maintenance of stable heterochromatin domains by dynamic HP1 binding. Science 2003; 299:721 - 725
  • Lavigne M, Eskeland R, Azebi S, Saint-Andre V, Jang SM, Batsche E, et al. Interaction of HP1 and Brg1/Brm with the globular domain of histone H3 is required for HP1-mediated repression. PLoS Genet 2009; 5:1000769
  • Minc E, Allory Y, Courvalin JC, Buendia B. Immunolocalization of HP1 proteins in metaphasic mammalian chromosomes. Methods Cell Sci 2001; 23:171 - 174
  • Smith MM. Centromeres and variant histones: what, where, when and why?. Curr Opin Cell Biol 2002; 14:279 - 285
  • Peters AH, O'Carroll D, Scherthan H, Mechtler K, Sauer S, Schofer C, et al. Loss of the Suv39 h histone methyltransferases impairs mammalian heterochromatin and genome stability. Cell 2001; 107:323 - 337
  • Metzger E, Wissmann M, Yin N, Muller JM, Schneider R, Peters AH, et al. LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription. Nature 2005; 437:436 - 439
  • Loh YH, Zhang W, Chen X, George J, Ng HH. Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells. Genes Dev 2007; 21:2545 - 2557
  • Shumaker DK, Dechat T, Kohlmaier A, Adam SA, Bozovsky MR, Erdos MR, et al. Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging. Proc Natl Acad Sci USA 2006; 103:8703 - 8708
  • Klochkov DB, Gavrilov AA, Vassetzky YS, Razin SV. Early replication timing of the chicken alpha-globin gene domain correlates with its open chromatin state in cells of different lineages. Genomics 2009; 93:481 - 486
  • Rudd MK, Willard HF. Analysis of the centromeric regions of the human genome assembly. Trends Genet 2004; 20:529 - 533
  • Finelli P, Antonacci R, Marzella R, Lonoce A, Archidiacono N, Rocchi M. Structural organization of multiple alphoid subsets coexisting on human chromosomes 1, 4, 5, 7, 9, 15, 18 and 19. Genomics 1996; 38:325 - 330
  • Pironon N, Puechberty J, Roizes G. Molecular and evolutionary characteristics of the fraction of human alpha satellite DNA associated with CENP-A at the centromeres of chromosomes 1, 5, 19 and 21. BMC Genomics 2010; 11:195
  • Rizzi N, Denegri M, Chiodi I, Corioni M, Valgardsdottir R, Cobianchi F, et al. Transcriptional activation of a constitutive heterochromatic domain of the human genome in response to heat shock. Mol Biol Cell 2004; 15:543 - 551
  • Valgardsdottir R, Chiodi I, Giordano M, Rossi A, Bazzini S, Ghigna C, et al. Transcription of Satellite III non-coding RNAs is a general stress response in human cells. Nucleic Acids Res 2008; 36:423 - 434
  • Fanti L, Pimpinelli S. HP1: a functionally multifaceted protein. Curr Opin Genet Dev 2008; 18:169 - 174
  • Saunders WS, Chue C, Goebl M, Craig C, Clark RF, Powers JA, et al. Molecular cloning of a human homologue of Drosophila heterochromatin protein HP1 using anti-centromere autoantibodies with anti-chromo specificity. J Cell Sci 1993; 104:573 - 582
  • Mateos-Langerak J, Brink MC, Luijsterburg MS, van der Kraan I, van Driel R, Verschure PJ. Pericentromeric heterochromatin domains are maintained without accumulation of HP1. Mol Biol Cell 2007; 18:1464 - 1471
  • Verschure PJ, van der Kraan I, de Leeuw W, van der Vlag J, Carpenter AE, Belmont AS, et al. In vivo HP1 targeting causes large-scale chromatin condensation and enhanced histone lysine methylation. Mol Cell Biol 2005; 25:4552 - 4564
  • Fischer T, Cui B, Dhakshnamoorthy J, Zhou M, Rubin C, Zofall M, et al. Diverse roles of HP1 proteins in heterochromatin assembly and functions in fission yeast. Proc Natl Acad Sci USA 2009; 106:8998 - 9003
  • Grewal SI, Jia S. Heterochromatin revisited. Nat Rev Genet 2007; 8:35 - 46
  • Vassallo MF, Tanese N. Isoform-specific interaction of HP1 with human TAFII130. Proc Natl Acad Sci USA 2002; 99:5919 - 5924
  • Smallwood A, Black JC, Tanese N, Pradhan S, Carey M. HP1-mediated silencing targets Pol II coactivator complexes. Nat Struct Mol Biol 2008; 15:318 - 320
  • Smallwood A, Esteve PO, Pradhan S, Carey M. Functional cooperation between HP1 and DNMT1 mediates gene silencing. Genes Dev 2007; 21:1169 - 1178
  • Eymery A, Souchier C, Vourc'h C, Jolly C. Heat shock factor 1 binds to and transcribes satellite II and III sequences at several pericentromeric regions in heat-shocked cells. Exp Cell Res 2010; 316:1845 - 1855
  • Eskeland R, Eberharter A, Imhof A. HP1 binding to chromatin methylated at H3K9 is enhanced by auxiliary factors. Mol Cell Biol 2007; 27:453 - 465
  • Meehan RR, Kao CF, Pennings S. HP1 binding to native chromatin in vitro is determined by the hinge region and not by the chromodomain. EMBO J 2003; 22:3164 - 3174
  • Mateescu B, England P, Halgand F, Yaniv M, Muchardt C. Tethering of HP1 proteins to chromatin is relieved by phosphoacetylation of histone H3. EMBO Rep 2004; 5:490 - 496
  • Fischle W, Tseng BS, Dormann HL, Ueberheide BM, Garcia BA, Shabanowitz J, et al. Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylation. Nature 2005; 438:1116 - 1122
  • Dawson MA, Bannister AJ, Gottgens B, Foster SD, Bartke T, Green AR, et al. JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin. Nature 2009; 461:819 - 822
  • Behera R, Kumar V, Lohite K, Karnik S, Kundu GC. Activation of JAK2/STAT3 signaling by osteopontin promotes tumor growth in human breast cancer cells. Carcinogenesis 2010; 31:192 - 200
  • Cheng MB, Zhang Y, Zhong X, Sutter B, Cao CY, Chen XS, et al. Stat1 mediates an auto-regulation of hsp90beta gene in heat shock response. Cell Signal 2010; 22:1206 - 1213

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