629
Views
36
CrossRef citations to date
0
Altmetric
Brief Report

Heritability and role for the environment in DNA methylation in AXL receptor tyrosine kinase

, &
Pages 895-898 | Received 10 Jan 2011, Accepted 06 Apr 2011, Published online: 01 Jul 2011

References

  • O'Bryan JP, Frye RA, Cogswell PC, Neubauer A, Kitch B, Prokop C, et al. Axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase. Mol Cell Biol 1991; 11:5016 - 5031
  • Hafizi S, Dahlback B. Gas6 and protein s. Vitamin k-dependent ligands for the axl receptor tyrosine kinase subfamily. FEBS J 2006; 273:5231 - 5244
  • Grommes C, Lee CY, Wilkinson BL, Jiang Q, Koenigsknecht-Talboo JL, Varnum B, et al. Regulation of microglial phagocytosis and inflammatory gene expression by gas6 acting on the axl/mer family of tyrosine kinases. J Neuroimmune Pharmacol 2008; 3:130 - 140
  • Park IK, Giovenzana C, Hughes TL, Yu J, Trotta R, Caligiuri MA. The axl/gas6 pathway is required for optimal cytokine signaling during human natural killer cell development. Blood 2009; 113:2470 - 2477
  • Jacob ST, Motiwala T. Epigenetic regulation of protein tyrosine phosphatases: Potential molecular targets for cancer therapy. Cancer Gene Ther 2005; 12:665 - 672
  • Mudduluru G, Allgayer H. The human receptor tyrosine kinase axl gene—promoter characterization and regulation of constitutive expression by sp1, sp3 and cpg methylation. Biosci Rep 2008; 28:161 - 176
  • Boks MP, Derks EM, Weisenberger DJ, Strengman E, Janson E, Sommer IE, et al. The relationship of DNA methylation with age, gender and genotype in twins and healthy controls. PLoS One 2009; 4:6767
  • Choufani S, Shapiro JS, Susiarjo M, Butcher DT, Grafodatskaya D, Lou Y, et al. A novel approach identifies new differentially methylated regions (dmrs) associated with imprinted genes. Genome Res 2011;
  • Fraga MF, Ballestar E, Paz MF, Ropero S, Setien F, Ballestar ML, et al. Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci USA 2005; 102:10604 - 10609
  • Martin GM. Epigenetic drift in aging identical twins. Proc Natl Acad Sci USA 2005; 102:10413 - 10414
  • Peters JM, Avol E, Gauderman WJ, Linn WS, Navidi W, London SJ, et al. A study of twelve Southern california communities with differing levels and types of air pollution. Ii. Effects on pulmonary function. Am J Respir Crit Care Med 1999; 159:768 - 775
  • Peters JM, Avol E, Navidi W, London SJ, Gauderman WJ, Lurmann F, et al. A study of twelve Southern california communities with differing levels and types of air pollution. I. Prevalence of respiratory morbidity. Am J Respir Crit Care Med 1999; 159:760 - 767
  • Breton CV, Byun HM, Wenten M, Pan F, Yang A, Gilliland FD. Prenatal tobacco smoke exposure affects global and gene-specific DNA methylation. Am J Respir Crit Care Med 2009; 180:462 - 467
  • Jirtle RL, Skinner MK. Environmental epigenomics and disease susceptibility. Nat Rev Genet 2007; 8:253 - 262
  • Byun HM, Siegmund KD, Pan F, Weisenberger DJ, Kanel G, Laird PW, et al. Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns. Hum Mol Genet 2009; 18:4808 - 4817
  • Falconer DS, Mackay TFC. Longman Group, Ed. Heritability. Introduction to quantitative genetics 1996; Harlow Essex, UK Pearson Education Limited 160 - 183
  • Khoury MJ, Beaty TH, Cohen BH. Oxford University Press. Genetic Approaches to Familial Aggregation I. Analysis of Heritability. Fundamentals of genetic epidemiology 1993; New York Oxford University Press 200 - 232
  • Waterland RA, Lin JR, Smith CA, Jirtle RL. Post-weaning diet affects genomic imprinting at the insulin-like growth factor 2 (igf2) locus. Hum Mol Genet 2006; 15:705 - 716
  • Waterland RA, Jirtle RL. Transposable elements: Targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol 2003; 23:5293 - 5300

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.